公开(公告)号：US12128179B2

公开(公告)日：2024-10-29

申请号：US17895867

申请日：2022-08-25

申请人： RAI Strategic Holdings, Inc.

发明人： David Allan Brammer ,  David Jackson ,  Nigel Flynn ,  Eric T. Hunt ,  Stephen Benson Sears ,  Dennis Lee Potter

IPC分类号： A61M15/02 ,  A24F40/10 ,  A24F40/42 ,  A24F40/44 ,  A24F40/48 ,  A24F40/485 ,  A24F40/50 ,  A61M11/00 ,  A61M11/04 ,  A61M15/06 ,  A61M16/00 ,  F24H1/00 ,  H05B3/02

CPC分类号： A61M15/025 ,  A24F40/42 ,  A24F40/44 ,  A24F40/48 ,  A24F40/485 ,  A24F40/50 ,  A61M11/007 ,  A61M15/06 ,  F24H1/0018 ,  H05B3/02 ,  A24F40/10 ,  A61M11/042 ,  A61M2016/0024 ,  A61M2205/8206

摘要： The present disclosure relates to aerosol delivery devices. The aerosol delivery devices include mechanisms configured to deliver an aerosol precursor composition from a reservoir to an atomizer including a vaporization heating element to produce a vapor. For example, a bubble jet head may be configured to dispense the aerosol precursor composition to the atomizer. The bubble jet head may be fixedly coupled to the atomizer. The bubble jet head may include a precursor inlet, an ejection heating element, and a precursor nozzle. The atomizer may include a vaporization heating element.

公开(公告)号：US12128175B2

公开(公告)日：2024-10-29

申请号：US16668026

申请日：2019-10-30

申请人： CannaKorp, Inc.

发明人： Michael Patrick Bourque

IPC分类号： A61M15/00 ,  A61M11/00 ,  A61M11/02 ,  A61M11/04 ,  G16H40/63 ,  A61L9/03

CPC分类号： A61M15/0023 ,  A61M11/003 ,  A61M11/02 ,  A61M11/042 ,  A61M15/0003 ,  A61M15/0005 ,  A61M15/0016 ,  A61M15/002 ,  A61M15/0028 ,  A61M15/0035 ,  A61M15/0043 ,  A61M15/0086 ,  A61M15/0098 ,  G16H40/63 ,  A61L9/03 ,  A61M15/0066 ,  A61M2205/276 ,  A61M2205/3306 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/3653 ,  A61M2205/368 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2205/6072 ,  A61M2205/702 ,  A61M2205/8206 ,  A61M2205/8275 ,  A61M2205/8293 ,  A61M2209/045

摘要： The present disclosure relates to systems and methods for producing a consistent and effective herbal vapor. A sealed container pod may include a chamber wall defining an internal volume within which a pre-processed herbal composition (e.g., cannabis) is located. The container pod may include filters for the vapor produced from the herbal composition. The container pod may also include a support member for holding and evenly distributing the herbal composition within the internal volume during vaporization. A vaporizer may be configured to obtain information regarding the contents of the herbal composition. The vaporizer may expose the herbal composition to an automated series of timed temperature adjustments specifically tailored for producing a desirable herbal vapor. The herbal vapor may be collected into a bag and/or canister for subsequent consumption.

公开(公告)号：US12121667B2

公开(公告)日：2024-10-22

申请号：US17674067

申请日：2022-02-17

申请人： NEBU-TEC MED. PRODUKTE EIKE KERN GMBH

发明人： Stefan Kern

IPC分类号： A61M15/00 ,  A61M11/00 ,  A61M16/00 ,  A61M16/14

CPC分类号： A61M16/14 ,  A61M11/00 ,  A61M11/005 ,  A61M15/0021 ,  A61M15/0085 ,  A61M15/0086 ,  A61M16/0069 ,  A61M16/024 ,  A61M2016/0018 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M2205/3365

摘要： A method for performing an inhalation using a nebulizer includes filling a reservoir with a medication fluid or connecting a medication container to a designated connecting piece; connecting a nebulizer unit to a control unit and a mouthpiece, at least temporarily activating the nebulizer unit; atomizing the medication fluid into a fine particulate aerosol which is emitted into an aerosol chamber formed by the nebulizer unit and the mouthpiece during activation of the nebulizer unit; performing the inhalation, with a user enclosing the mouthpiece with the lips and during inhalation, drawing air from outside into the aerosol chamber, where the air mixes with the aerosol, and then passes further through the mouthpiece as an air stream and into the respiratory tract and, possibly into the user's lung; measuring a pressure within the aerosol chamber and/or a flow rate through the aerosol chamber or the mouthpiece using the control unit; activating the nebulizer unit with each breath on occurrence of at least one activation criterion detected using the control unit; and deactivating the nebulizer unit with fulfilment of at least one stop criterion, wherein from a degree of fulfilment of the at least one activation and/or stop criterion, a weighted average value is formed and the inhalation is started when the weighted average value exceeds a threshold value.

公开(公告)号：US20240344226A1

公开(公告)日：2024-10-17

申请号：US18411467

申请日：2024-01-12

申请人： Stamford Devices Limited

发明人： Hong XU

IPC分类号： C25D7/00 ,  A61M11/00 ,  B05B17/00 ,  B41J2/16 ,  C25D1/00 ,  C25D3/38 ,  C25D3/46 ,  C25D3/48 ,  C25D3/54 ,  C25D5/00 ,  C25D5/02 ,  C25D5/10 ,  C25D5/34 ,  C25D5/48 ,  C25D5/54

CPC分类号： C25D7/00 ,  A61M11/005 ,  B05B17/0646 ,  B41J2/162 ,  B41J2/1625 ,  B41J2/1629 ,  B41J2/1631 ,  C25D1/003 ,  C25D3/38 ,  C25D3/46 ,  C25D3/48 ,  C25D3/54 ,  C25D5/022 ,  C25D5/10 ,  C25D5/34 ,  C25D5/48 ,  C25D5/54 ,  C25D5/611

摘要： In one embodiment, a method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described according to other embodiments.

公开(公告)号：US20240342450A1

公开(公告)日：2024-10-17

申请号：US18638604

申请日：2024-04-17

申请人： Children's National Medical Center ,  University of Maryland, College Park

发明人： Anthony Sandler ,  Reza Monfaredi ,  Tyler Salvador ,  Michele Saruwatari ,  Peter Kofinas

IPC分类号： A61M35/00 ,  A61L26/00 ,  A61M11/00

CPC分类号： A61M35/003 ,  A61L26/0052 ,  A61L26/0057 ,  A61L26/0076 ,  A61L26/0095 ,  A61M11/007

摘要： A solution blow spin device includes a syringe pump assembly, an airbrush adapter, and a handle base. The syringe pump assembly, airbrush adapter, and handle base are reversibly coupled to one another and configured to work in tandem to address wound dressing using a polymer solution and autologous skin cell suspension co-spray. The airbrush adapter includes multiple nozzles for deposition of multiple solutions sequentially or simultaneously in order to improve would dressing efficacy. The syringe pump assembly includes multiple syringes holding the multiple solutions, and the syringes can be emptied by individually addressable lead screws configured to translate blocks to depress syringe plungers when the lead screws are rotated via corresponding actuators.

公开(公告)号：US20240342408A1

公开(公告)日：2024-10-17

申请号：US18634022

申请日：2024-04-12

申请人： Aptar Radolfzell GmbH

发明人： Leonard WELSCH

IPC分类号： A61M15/08 ,  A24F42/20 ,  A24F42/60 ,  A61M11/00 ,  A61M11/04 ,  A61M15/00 ,  A61M15/06 ,  B65D83/28

CPC分类号： A61M15/08 ,  A24F42/20 ,  A24F42/60 ,  A61M11/006 ,  A61M11/04 ,  A61M15/009 ,  A61M15/06 ,  B65D83/28 ,  A61M2205/123

摘要： A liquid dispenser having a liquid reservoir, a liquid applicator and a conveying device for conveying liquid from the liquid reservoir) to the liquid applicator. The liquid dispenser has an applicator unit, on which the liquid applicator is provided, and a protective unit having a protective cover for protecting the applicator unit. The protective unit and the applicator unit can be displaced with respect to one another between a protective position and a use position. The liquid dispenser has an operating handle, via which operating handle the protective unit can be displaced from the protective position into the use position with respect to the applicator unit, and by which, in the use position, the conveying device can be actuated and liquid can be conveyed from the liquid reservoir to the liquid applicator.

公开(公告)号：US20240342404A1

公开(公告)日：2024-10-17

申请号：US18751627

申请日：2024-06-24

申请人： Norton (Waterford) Limited

发明人： Mark Milton-Edwards ,  Guilherme Safioti ,  Lena Granovsky ,  Michael Reich

IPC分类号： A61M15/00 ,  A61B5/00 ,  A61B5/08 ,  A61K31/138 ,  A61M11/00 ,  C07K16/24 ,  C07K16/28 ,  C07K16/42 ,  G16H20/10 ,  G16H20/13 ,  G16H50/30 ,  G16H50/70

CPC分类号： A61M15/009 ,  A61B5/0826 ,  A61B5/4848 ,  A61B5/7275 ,  A61K31/138 ,  A61M15/0001 ,  A61M15/0025 ,  A61M15/003 ,  A61M15/008 ,  A61M15/0091 ,  C07K16/244 ,  C07K16/247 ,  C07K16/2866 ,  C07K16/4291 ,  G16H20/10 ,  G16H20/13 ,  G16H50/30 ,  G16H50/70 ,  A61M11/00 ,  A61M15/0026 ,  A61M2202/064 ,  A61M2205/05 ,  A61M2205/18 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/3358 ,  A61M2205/3584 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2230/30 ,  A61M2230/40 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/52

摘要： Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.

公开(公告)号：US12115309B2

公开(公告)日：2024-10-15

申请号：US17118616

申请日：2020-12-11

申请人： BMC MEDICAL CO., LTD.

发明人： Lijun Liu ,  Jianxin Zhi ,  Zhi Zhuang ,  Min Chang

IPC分类号： A61M16/00 ,  A61L9/20 ,  A61M11/00 ,  A61M16/04 ,  A61M16/06 ,  A61M16/08 ,  A61M16/10 ,  A61M16/16 ,  G16H20/40 ,  G16H40/63

CPC分类号： A61M16/0066 ,  A61L9/20 ,  A61M16/1075 ,  A61M16/109 ,  A61M16/16 ,  A61M16/161 ,  G16H20/40 ,  A61L2209/12 ,  A61M2016/0027 ,  A61M2016/003 ,  A61M16/0465 ,  A61M16/06 ,  A61M16/0616 ,  A61M16/0666 ,  A61M16/1055 ,  A61M16/107 ,  A61M2205/3306 ,  A61M2205/3368 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/42 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/587 ,  A61M2209/10 ,  A61M2230/42

摘要： A respiratory ventilation apparatus configured to deliver a respiratory gas to a patient interface is provided. The apparatus may include a gas pressurization unit configured to generate a pressurized respiratory gas, a gas inlet port configured to introduce the respiratory gas into the respiratory ventilation apparatus, a gas outlet port configured to discharge the pressurized respiratory gas to a respiration tube, a detection module configured to detect the pressure of the pressurized respiratory gas, at least one non-volatile memory configured to store a plurality of parameters and a plurality of programs, and one or more controllers. The one or more controllers may be configured to initiate the respiratory ventilation apparatus upon a boot operation, and/or initiate a program that constantly reads information from the detection module, and controls the pressure of the pressurized respiratory gas using the information read from the detection module and at least one parameter.

公开(公告)号：US20240335625A1

公开(公告)日：2024-10-10

申请号：US18579626

申请日：2022-07-15

申请人： Yaowu DING

发明人： Yaowu DING

IPC分类号： A61M11/00

CPC分类号： A61M11/007 ,  A61M2202/0007 ,  A61M2205/583 ,  A61M2210/0618

摘要： A spray drug administration apparatus includes: a sleeve forming with a lumen that is capable of containing a cylinder of a syringe; and at least one nozzle provided at a front end of the sleeve and being in communication with the lumen of the sleeve. A direction of axis of the nozzle is angled with respect to a direction of axis of the sleeve. A finger plate can be formed at or adjacent to a rear end of the sleeve. Two nozzles can be provided at a front end of the sleeve. The spray drug administration apparatus can realize complete spraying of medicinal liquid, even drug administration, and leakage prevention. And further disclosed is a spray drug administration including this apparatus.

公开(公告)号：US20240335623A1

公开(公告)日：2024-10-10

申请号：US18743548

申请日：2024-06-14

申请人： Altria Client Services LLC

发明人： Srinivasan JANARDHAN ,  Georgios D. KARLES ,  Yezdi B. PITHAWALLA ,  Christopher SIMPSON

IPC分类号： A61M11/00 ,  A24F40/10 ,  A24F40/40 ,  A24F40/48 ,  A24F40/485 ,  A24F40/57 ,  A61M11/04 ,  A61M15/00 ,  A61M15/06 ,  A61M16/20

CPC分类号： A61M11/002 ,  A24F40/40 ,  A24F40/485 ,  A24F40/57 ,  A61M11/042 ,  A61M15/0021 ,  A61M15/06 ,  A24F40/10 ,  A24F40/48 ,  A61M11/008 ,  A61M15/002 ,  A61M16/202 ,  A61M2205/3368 ,  A61M2205/3606 ,  A61M2205/3653 ,  A61M2205/8206 ,  A61M2206/14 ,  A61M2206/16

摘要： An electronic smoking article includes an aerosol generator and a mouth end insert. The mouth end insert includes a mechanical aerosol converter surface having the capacity to improve characteristics of aerosol produced by the aerosol generator, including sensory attributes.