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公开(公告)号:US20240327838A1
公开(公告)日:2024-10-03
申请号:US18492683
申请日:2023-10-23
IPC分类号: C12N15/113 , A61K9/00 , A61K31/404 , A61K31/47 , A61K31/7105 , A61K31/713 , A61M11/00 , A61P11/00
CPC分类号: C12N15/113 , A61K9/0019 , A61K9/0075 , A61K9/0078 , A61K31/404 , A61K31/47 , A61K31/7105 , A61K31/713 , A61P11/00 , A61M11/005 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/3231 , C12N2310/3341 , C12N2310/341 , C12N2310/345 , C12N2310/346 , C12N2320/31 , C12N2320/32 , C12N2320/35
摘要: The present embodiments provide methods, compounds, and compositions useful for inhibiting ENaC expression, which may be useful for treating, preventing, or ameliorating a disease associated with ENaC.
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公开(公告)号:US12083268B2
公开(公告)日:2024-09-10
申请号:US18057486
申请日:2022-11-21
发明人: Janis Kay Shute
IPC分类号: A61M15/00 , A61K9/00 , A61K31/137 , A61K31/537 , A61K31/573 , A61K31/727 , A61K45/06 , A61M11/00 , A61P11/00
CPC分类号: A61M15/0085 , A61K9/0078 , A61K31/137 , A61K31/573 , A61K31/727 , A61K45/06 , A61M11/005 , A61P11/00 , A61M2209/06 , A61K31/727 , A61K2300/00 , A61K31/137 , A61K2300/00 , A61K31/573 , A61K2300/00
摘要: The present invention relates to a handheld vibrating mesh nebuliser for delivery of a medicament to the respiratory system in therapy. The present invention also relates to a supply container for loading the nebuliser with liquid medicament. The present invention also relates to a kit for delivery of a medicament to a respiratory system and a method of loading a vibrating mesh nebuliser with liquid medicament from a supply container. The present invention also relates to compositions for use in a method of treatment of a respiratory disease in a patient by therapy.
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公开(公告)号:US20240269401A1
公开(公告)日:2024-08-15
申请号:US18609789
申请日:2024-03-19
发明人: Mohammed Alshaiba Saleh Ghannam Almazrouei , Sajid Bhatti , Jeff Machovec , Clement Lamoureux , Imad Lahoud
IPC分类号: A61M15/00 , A24B15/167 , A24F40/05 , A24F40/10 , A24F40/44 , A24F40/48 , A24F40/50 , A24F40/51 , A24F40/53 , A24F40/65 , A61M11/00 , A61M15/06 , B05B17/00 , B05B17/06
CPC分类号: A61M15/0085 , A24B15/167 , A24F40/05 , A24F40/10 , A24F40/44 , A24F40/48 , A24F40/50 , A24F40/51 , A24F40/53 , A24F40/65 , A61M11/005 , A61M15/06 , B05B17/063 , B05B17/0661 , B05B17/0669 , B05B17/0684 , A61M15/0021 , A61M15/0081 , A61M2205/0294 , A61M2205/276 , A61M2205/3331 , A61M2205/3592 , A61M2205/50 , A61M2205/52 , A61M2205/60 , A61M2205/8206 , A61M2205/8212 , A61M2205/8237 , A61M2230/40 , B05B17/0646 , B06B2201/77
摘要: A mist inhaler device (200) for generating a mist for inhalation by a user. The device includes a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).
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公开(公告)号:US20240269397A1
公开(公告)日:2024-08-15
申请号:US18382637
申请日:2023-10-23
发明人: Charles Eric Hunter , Michael Scoggin , Jeffrey Miller , Jose Salazar , Brian Beach , Caley Modlin , Matthew Culpepper , Jianqiang Li , Chengjie Li , Shi Bo Wang , Chao-Ping Lee , Gregory Rapp , Judson Sidney Clements
CPC分类号: A61M11/003 , A61M11/005 , A61M15/0001 , A61M15/002 , A61M15/0085 , A61M2206/11
摘要: A droplet delivery device includes a housing with a mouthpiece port or outlet from a nasal device for releasing fluid droplets, a fluid reservoir, and an ejector bracket having a membrane positioned between a mesh with a plurality of openings and a vibrating member that is coupled to an electronic transducer, such as an ultrasonic transducer. The transducer vibrates the vibrating member which causes the membrane to push fluid supplied by the reservoir through the mesh to generate droplets in an ejected stream released through the outlet.
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公开(公告)号:US12053577B2
公开(公告)日:2024-08-06
申请号:US17253499
申请日:2019-06-17
发明人: Bruno Brandimarte
CPC分类号: A61M15/06 , A61M11/005 , A61M11/042 , A61M15/0085 , A61M15/0086
摘要: A system (1) is configured to deliver a liquid substance in the form of dry steam in the context of respiratory therapy. The system (1) comprises: —a reservoir (2) for containing the substance; —dispensing means (6) of the substance in fluid connection with said reservoir (2); —first vibration type electromechanical vaporization means (3), configured to apply vibrations to the substance contained within said reservoir (2) in such a way as to bring the substance into a dry steam state; —second heating vaporization means (4) configured to release thermal energy to the substance contained in said reservoir (2), in such a way as to bring the substance into a dry steam state; —a control unit (7) configured to control the actuation of said first mechanical vaporization means (3) and/or said second heating vaporization means (4) according to a predetermined delivery program.
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公开(公告)号:US12042598B2
公开(公告)日:2024-07-23
申请号:US17320026
申请日:2021-05-13
申请人: GoFire, Inc.
CPC分类号: A61M11/042 , A61M11/005 , G06F1/28 , A61M2205/3327 , A61M2205/3553 , A61M2205/3584 , A61M2205/52 , A61M2205/8206
摘要: Provided is a system and method for a vaporizer journaling device. The journaling adapter has a housing providing a first coupler at a first end for engaging a hand-held vaporizer device and a second coupler at a second end for engaging a removable power supply. The housing encloses a first electrical pathway structured and arranged to interconnect an engaged vaporizer device and the removable power supply. A wireless transceiver is also enclosed and structured and arranged for wireless communication with at least one remote computing device. A control system having at least one processor is structured and arranged to sense a flow of current through the first electrical pathway to the vaporizer device, detect a vaporizing event, and communicate by the wireless transceiver each vaporizing event to the at least one remote computing device. An associated method of use is also provided.
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公开(公告)号:US20240226463A9
公开(公告)日:2024-07-11
申请号:US18327363
申请日:2023-06-01
发明人: Simon Robinson , Justin Esterberg , Brad Douglass
IPC分类号: A61M11/04 , A24B15/167 , A24F40/05 , A24F40/10 , A24F40/30 , A24F40/42 , A24F40/46 , A24F40/48 , A24F40/50 , A24F40/65 , A61K9/00 , A61K36/185 , A61M11/00 , A61M15/00 , A61M15/06 , A61M15/08
CPC分类号: A61M11/041 , A24B15/167 , A24F40/05 , A24F40/10 , A24F40/30 , A24F40/42 , A24F40/46 , A24F40/48 , A24F40/50 , A24F40/65 , A61K9/0078 , A61K36/185 , A61M11/005 , A61M15/0021 , A61M15/0085 , A61M15/06 , A61M15/08 , A61M2205/502
摘要: A nebulizer device for administering aerosol cannabinoid mixtures to a user includes a mouthpiece, a first reservoir, a second reservoir, and a nebulizer device. The nebulizer module is configured to receive a first dosage of the first liquid from the first reservoir and a second dosage of a second liquid from the second reservoir. The nebulizer module is also configured to transform the first liquid into an inhalant and the second liquid into an aerosol that are provided to the user through the mouthpiece. The device further includes a dosage module configured to independently control the delivery of the first liquid and the second liquid to the nebulizer module to set a ratio between the first dosage of the first liquid and the second dosage of the second liquid. The dosage module thereby controls a composition of an aerosol cannabinoid mixture administered to the user.
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公开(公告)号:US20240226462A1
公开(公告)日:2024-07-11
申请号:US18408349
申请日:2024-01-09
发明人: Charles Eric Hunter , Gregory Rapp
IPC分类号: A61M11/00
CPC分类号: A61M11/005 , A61M2205/18 , A61M2205/33
摘要: A droplet delivery device includes a high dose confidence mode that monitors a user's inhalation of a composition and activates and deactivates aerosol generation via monitoring the user's inhalation to assist the user to complete a full dosage when a user does not inhale a full dosage of the composition when using the device.
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公开(公告)号:US20240198016A1
公开(公告)日:2024-06-20
申请号:US18594799
申请日:2024-03-04
发明人: Shaun Porter , Louise Sweeney , Ronan MacLoughlin , Jim Fink , Aidan Duffy , Claire Lillis , Conor Duffy , Fran Keating
IPC分类号: A61M11/00 , A61M15/00 , A61M15/08 , A61M16/00 , A61M16/04 , A61M16/06 , A61M16/08 , A61M16/14 , A61M16/16 , B05B12/08 , B05B17/00
CPC分类号: A61M11/005 , A61M11/001 , A61M15/0085 , A61M15/08 , A61M16/0003 , A61M16/022 , A61M16/026 , A61M16/0465 , A61M16/0488 , A61M16/0666 , A61M16/0672 , A61M16/0816 , A61M16/14 , B05B17/0646 , A61M2016/0018 , A61M2016/0021 , A61M2016/0027 , A61M2016/0033 , A61M2016/0039 , A61M2016/0042 , A61M16/04 , A61M16/16 , A61M2202/0488 , A61M2205/17 , A61M2205/3303 , A61M2205/332 , A61M2205/3327 , A61M2205/3334 , A61M2205/3368 , A61M2205/3375 , A61M2205/3569 , A61M2205/3592 , A61M2205/505 , A61M2209/045 , A61M2209/084 , A61M2230/40 , A61M2230/432 , A61M2230/50 , A61M2230/63 , A61M2240/00 , B05B12/08
摘要: An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor that emits a signal as the patient breathes. A controller couples to the aerosol generator, the pump, and the breath sensor. In operation, the controller receives the signal from the breath sensor, controls a flow of fluid to the aerosol generator in response to the signal, and controls the aerosol generator to start aerosolizing the fluid before the patient inhales.
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公开(公告)号:US20240148987A1
公开(公告)日:2024-05-09
申请号:US18411786
申请日:2024-01-12
发明人: Nirav Mehta , Palkesh Agrawal
CPC分类号: A61M11/005 , H04R17/00 , A61M2202/04 , A61M2210/1021
摘要: A device, for delivery of aerosolized drug in a portion of a body, comprising: a nozzle (100) comprising a head portion extending, distally, into an elongate shaft (108), said head portion comprising: piezoelectric transducers (104, 106) mounted between electrically conductive electrode discs (103, 105), said piezoelectric transducers (104, 106) creating capillary waves in a liquid film causing atomization of drug/s while passing through said nozzle (100); an aperture (101) on said nozzle (100), through which tubing (112) is connected, said aperture (101) follows through with a passage (300) ensconced in said elongate shaft (108), and passing through said piezoelectric transducers (104, 106) and said electrically conductive electrode discs (103, 105) in order to allow passage of drug received through said tubing (112); and said elongate shaft (108) supporting a body member (107) at its operative proximal end and having an opening (109), said drug being dispensed through said opening (109).
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