公开(公告)号：US20190074445A1

公开(公告)日：2019-03-07

申请号：US16119308

申请日：2018-08-31

Applicant: Samsung Electronics Co., Ltd. ,  Ewha University - Industry Collaboration Foundation

Inventor： Sooghang IHN ,  Youngmin YOU ,  Sonam KIM ,  Sinheui KIM ,  Seungyeon YI ,  Sunghan KIM ,  Changho NOH ,  Soohwan SUL ,  Myungsun SIM ,  Hasup LEE

IPC: H01L51/00 ,  C07D311/10 ,  C07C49/784 ,  C07C49/786 ,  C07C49/683

Abstract: An organic light-emitting device comprising: a first electrode; a second electrode facing the first electrode; and an organic layer disposed between the first electrode and the second electrode, wherein the organic layer comprises an emission layer and a fluorescent compound, wherein the fluorescent compound comprises a 3n-π*-to-1π-π* energy transition from a 3n-π* excited state to a 1π-π* excited state, an energy level in a 1n-π* excited state of the fluorescent compound is greater than an energy level in the 1π-π* excited state of the fluorescent compound, the fluorescent compound emits a fluorescent light by radiative energy transition of an exciton in the 1π-π* excited state to a ground state, and the energy level in the 1n-π* excited state, the energy level in the 1π-π* excited state, and the energy level in the 3n-π* excited state are each independently calculated by using a time dependent-Density Functional Theory method.

公开(公告)号：US09656256B2

公开(公告)日：2017-05-23

申请号：US14910456

申请日：2014-05-28

Applicant: Shanghai Research Institute of Chemical Industry

Inventor： An Shen ,  Yucai Cao ,  Xiangyang Wu ,  Xiaofeng Ye ,  Chen Ni ,  Yongqing Li

IPC: B01J31/08 ,  B01J31/10 ,  B01J35/08 ,  B01J21/18 ,  C07C201/14 ,  C07D301/12 ,  C01B31/02 ,  B01J31/22 ,  B01J31/28 ,  C07C67/343 ,  C07D333/16 ,  C07C45/68 ,  C07C49/67 ,  C07C49/784 ,  C07D295/096 ,  C07D307/36 ,  C07F15/00 ,  C07C209/10 ,  C07C1/26 ,  C07C1/32 ,  C07C213/08 ,  C07D213/16 ,  C07D265/30 ,  C07D333/10

CPC classification number: B01J31/2273 ,  B01J31/1805 ,  B01J31/2226 ,  B01J31/28 ,  B01J2231/4205 ,  B01J2231/4277 ,  B01J2531/824 ,  C07C1/26 ,  C07C1/321 ,  C07C1/325 ,  C07C1/326 ,  C07C45/68 ,  C07C49/67 ,  C07C49/784 ,  C07C67/343 ,  C07C209/10 ,  C07C213/08 ,  C07C2531/22 ,  C07C2601/14 ,  C07D213/16 ,  C07D265/30 ,  C07D295/096 ,  C07D307/36 ,  C07D333/10 ,  C07D333/16 ,  C07F15/006 ,  C07C69/734 ,  C07C69/618

Abstract: The present invention relates to an n-heterocyclic carbene (NHC) type palladium catalyst and its preparation method as well as applications. Its preparation process is as below: select glyoxal as the raw material to synthesize glyoxaldiimine in the presence of Lewis acid or Bronsted acid, and then react with paraformaldehyde to get the NHC type ligand. Use palladium(II) to react with the compound containing carbon-nitrogen double bonds to get palladium(II) cyclic dimer; make the palladium cyclic dimer and the NHC type ligand coordinated to get the NHC type palladium catalyst. The palladium catalyst with a brand new structure according to the present invention, boasts high activity and multi-purpose. In addition, it shows excellent reaction activity in a lot of catalytic-coupling reactions including Suzuki-Miyaura, Heck, Buchwald-Hartwig, Kumada-Tamao-Corriu, Sonogashira, Negishi and α-ketone arylation reactions, and some reactions even can be carried out with the presence of an extremely low concentration of catalyst, exhibiting favorable industrialization prospect.

公开(公告)号：US20170125676A1

公开(公告)日：2017-05-04

申请号：US15402750

申请日：2017-01-10

Applicant: Merck Patent GmbH

Inventor： Rémi Manouk ANÉMIAN ,  Susanne HEUN ,  Thomas EBERLE ,  Philipp STOESSEL

IPC: H01L51/00 ,  C09K11/02 ,  C07C15/38 ,  C07D251/24 ,  C07D403/04 ,  C07F15/00 ,  C09K11/06 ,  C07C49/784

CPC classification number: H01L51/005 ,  B32B2457/20 ,  C07C15/38 ,  C07C49/784 ,  C07C2603/24 ,  C07C2603/42 ,  C07D251/24 ,  C07D403/04 ,  C07F15/0033 ,  C09K11/02 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1029 ,  C09K2211/1059 ,  C09K2211/185 ,  H01L51/0003 ,  H01L51/0052 ,  H01L51/0054 ,  H01L51/0056 ,  H01L51/0058 ,  H01L51/0067 ,  H01L51/0072 ,  H01L51/0085 ,  H01L51/0508 ,  H01L51/42 ,  H01L51/5012 ,  H01L51/5016 ,  H01L51/5048 ,  H01L51/5056 ,  H01L51/5072 ,  H01L51/5088 ,  H01L51/5092 ,  H01L51/5096 ,  Y02E10/549 ,  Y10T428/10 ,  Y10T428/1036

Abstract: The present invention relates to a formula, comprising at least one solvent, and at least one functional composition of the general formula (I), wherein A is a functional structural element, B is a solvent-providing structural element, and k is an integer in the range of 1 to 20. The molecular weight of the functional composition is at least 550 g/mol, and the solvent-providing structural element B corresponds to the general formula ((L-I). Ar1, Ar2 JeWeUs, independently of each other, signify an aryl or heteroaryl group, which can be substituted with one or several discretionary residues R. Each X is, independently of one another, N or CR2, preferably CH. R1, R2, independently of one another, is hydrogen, a linear alkyl, alkoxy, or thioalkoxy group with 1 to 40 C atoms, or a branched or cyclic alkyl, alkoxy, or thioalkoxy group with 3 to 40 C atoms, or a silyl group, or a substituted keto group with 1 to 40 C atoms, an alkoxycarbonyl group with 2 to 40 C atoms, an aryloxycarbonyl group with 7 to 40 C atoms, a cyano group (—CN), a carbamoyl group (—C(═O)NH2), a haloformyl group (—C(═O)—X, wherein X signifies a halogen atom), a formyl group (—C(═O)—H), an isocyano group, an isocyanate group, a thiocyanate group or a thioisocyanate group, a hydroxy group, a nitro group, a CF3 group, Cl, Br, F, a cross-linkable group, or a substituted or non-substituted aromatic or heteroaromatic ring system with 5 to 60 ring atoms, or an aryloxy or heteroaryloxy group with 5 to 60 ring atoms, or a combination of these systems, wherein one or several of groups R1 and/or R2 can form a monocyclic or polycyclic, aliphatic or aromatic ring system with one another and/or with the ring to which group R1 is bound, and I is 0, 1, 2, 3 or 4, wherein the dashed linkage indicates the linkage to the functional structure element A. The present invention further relates to preferred compositions of the formula (I) and electronic devices containing said compositions.

公开(公告)号：US09303010B2

公开(公告)日：2016-04-05

申请号：US14547858

申请日：2014-11-19

Applicant: Samumed, LLC

Inventor： Sunil Kumar KC ,  David Mark Wallace ,  John Hood ,  Charlene F. Barroga

IPC: C07D409/06 ,  A61K31/357 ,  A61K31/381 ,  C07D319/16 ,  C07C49/784 ,  C07D213/50 ,  C07D319/18 ,  C07D405/06 ,  C07D405/10 ,  C07D407/10 ,  C07D409/10 ,  A61K9/00

CPC classification number: A61K31/4436 ,  A61K9/0014 ,  A61K31/12 ,  A61K31/357 ,  A61K31/381 ,  A61K31/4402 ,  A61K31/4433 ,  C07C49/784 ,  C07D213/50 ,  C07D319/16 ,  C07D319/18 ,  C07D405/06 ,  C07D405/10 ,  C07D407/10 ,  C07D409/06 ,  C07D409/10

Abstract: The present application discloses a compound which is which activates Wnt/β-catenin signaling and thus treats or prevents diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.

Abstract translation: 本申请公开了一种化合物，其活化Wnt / bgr-catenin信号传导，从而治疗或预防与信号转导相关的疾病，例如骨质疏松症和骨关节病; 成骨不全，骨缺损，骨折，牙周病，耳硬化症，伤口愈合，颅面缺损，溶瘤性骨病，与中枢神经系统分化和发育相关的创伤性脑损伤，包括帕金森病，中风，缺血性脑病，癫痫 ，阿尔茨海默病，抑郁症，双相性精神障碍，精神分裂症; 眼睛疾病如年龄相关性黄斑变性，糖尿病性黄斑水肿或视网膜色素变性以及与干细胞分化和生长相关的疾病，包括脱发，造血相关疾病和组织再生相关疾病。

公开(公告)号：US08975300B2

公开(公告)日：2015-03-10

申请号：US14100547

申请日：2013-12-09

Applicant: Esperion Therapeutics, Inc.

Inventor： Jean-Louis Henri Dasseux ,  Carmen Daniela Oniciu

IPC: A61K31/19 ,  C07C59/353 ,  C07C49/17 ,  C07C49/185 ,  C07C49/215 ,  C07C49/245 ,  C07C49/258 ,  C07C49/507 ,  C07C49/723 ,  C07C49/743 ,  C07C49/747 ,  C07C49/784 ,  C07C49/82 ,  C07C49/86 ,  C07C50/30 ,  C07C59/347 ,  C07C59/82 ,  C07C59/84 ,  C07C59/90 ,  C07C69/716 ,  C07C69/738 ,  C07C235/74 ,  C07C261/04 ,  C07C309/07 ,  C07C309/24 ,  C07D233/72 ,  C07D233/84 ,  C07D233/86 ,  C07D257/04 ,  C07D261/12 ,  C07D305/12 ,  C07D307/33 ,  C07D309/12 ,  C07D309/30 ,  C07D309/40 ,  C07F9/09 ,  C07F9/24 ,  C07F9/44

CPC classification number: C07C59/353 ,  C07C49/17 ,  C07C49/185 ,  C07C49/215 ,  C07C49/245 ,  C07C49/258 ,  C07C49/507 ,  C07C49/723 ,  C07C49/743 ,  C07C49/747 ,  C07C49/784 ,  C07C49/82 ,  C07C49/86 ,  C07C50/30 ,  C07C59/347 ,  C07C59/82 ,  C07C59/84 ,  C07C59/90 ,  C07C69/716 ,  C07C69/738 ,  C07C235/74 ,  C07C261/04 ,  C07C309/07 ,  C07C309/24 ,  C07C2601/08 ,  C07C2601/10 ,  C07C2601/14 ,  C07C2601/16 ,  C07D233/72 ,  C07D233/84 ,  C07D233/86 ,  C07D257/04 ,  C07D261/12 ,  C07D305/12 ,  C07D307/33 ,  C07D309/12 ,  C07D309/30 ,  C07D309/40 ,  C07F9/093 ,  C07F9/2425 ,  C07F9/4423

Abstract: The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising a ketone compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.

Abstract translation: 本发明涉及新颖的酮化合物，包含酮化合物的组合物，以及可用于治疗和预防心血管疾病，血脂异常，dysproteinemias和葡萄糖代谢紊乱的方法，包括施用包含酮化合物的组合物。 本发明的化合物，组合物和方法也可用于治疗和预防阿尔茨海默病，综合征X，过氧化物酶体增殖物激活受体相关病症，败血症，血栓形成障碍，肥胖症，胰腺炎，高血压，肾脏疾病，癌症，炎症和 阳。 在某些实施方案中，本发明的化合物，组合物和方法可用于与其它治疗剂如降胆固醇和降血糖药物组合治疗。

公开(公告)号：US08921413B2

公开(公告)日：2014-12-30

申请号：US14086529

申请日：2013-11-21

Applicant: Samumed, LLC

Inventor： Sunil Kumar KC ,  David Mark Wallace ,  John Hood ,  Charlene F. Barroga

IPC: C07D319/18 ,  A61K31/357 ,  C07C49/784 ,  C07D213/50 ,  C07D405/06 ,  C07D405/10 ,  C07D407/10 ,  C07D409/06 ,  C07D409/10

CPC classification number: A61K31/4436 ,  A61K9/0014 ,  A61K31/12 ,  A61K31/357 ,  A61K31/381 ,  A61K31/4402 ,  A61K31/4433 ,  C07C49/784 ,  C07D213/50 ,  C07D319/16 ,  C07D319/18 ,  C07D405/06 ,  C07D405/10 ,  C07D407/10 ,  C07D409/06 ,  C07D409/10

Abstract: The present invention discloses β-diketones, γ-diketones or γ-hydroxyketones or analogs thereof, that activate Wnt/β-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.

Abstract translation: 本发明公开了用于激活Wnt / / b-c-catenin信号传导的β-二酮，γ-二酮或γ-羟基酮或其类似物，从而治疗或预防与信号转导相关的疾病，如骨质疏松症和骨关节病; 成骨不全，骨缺损，骨折，牙周病，耳硬化症，伤口愈合，颅面缺损，溶瘤性骨病，与中枢神经系统分化和发育相关的创伤性脑损伤，包括帕金森病，中风，缺血性脑病，癫痫 ，阿尔茨海默病，抑郁症，双相性精神障碍，精神分裂症; 眼睛疾病如年龄相关性黄斑变性，糖尿病性黄斑水肿或视网膜色素变性以及与干细胞分化和生长相关的疾病，包括脱发，造血相关疾病和组织再生相关疾病。

公开(公告)号：US06958373B2

公开(公告)日：2005-10-25

申请号：US10333646

申请日：2001-07-25

Applicant: Walter Partenheimer

Inventor： Walter Partenheimer

IPC: C07D213/807 ,  B01J31/26 ,  C07B61/00 ,  C07C45/27 ,  C07C49/784 ,  C07C51/16 ,  C07C53/08 ,  C07C53/16 ,  C07C55/10 ,  C07C55/12 ,  C07C55/14 ,  C07C57/145 ,  C07C57/15 ,  C07C59/06 ,  C07C59/125 ,  C07C63/06 ,  C07C63/26 ,  C07C63/38 ,  C08F8/06 ,  C08J11/16

CPC classification number: C08J11/16 ,  C08F8/50 ,  C08J2323/00 ,  C08J2325/06 ,  C08J2327/06 ,  C08J2339/08 ,  C08J2367/00 ,  Y02W30/705 ,  C08F8/06 ,  C08F112/08 ,  C08F126/06 ,  C08F110/06 ,  C08F114/06 ,  C08F226/06

Abstract: Polymeric materials are recycled by transformation to useful chemicals by oxidization in the liquid phase using acetic acid as a solvent and a metal bromide catalyst.

Abstract translation: 通过使用乙酸作为溶剂和金属溴化物催化剂通过在液相中氧化转化成有用的化学物质来回收聚合材料。

公开(公告)号：US06933257B2

公开(公告)日：2005-08-23

申请号：US10680334

申请日：2003-10-07

Applicant: Mark Andrew Harmer ,  Qun Sun

Inventor： Mark Andrew Harmer ,  Qun Sun

IPC: C08J5/20 ,  B01J21/08 ,  B01J31/08 ,  B01J31/10 ,  B01J31/16 ,  B01J31/24 ,  B01J31/40 ,  B01J35/10 ,  C07B61/00 ,  C07C2/02 ,  C07C2/08 ,  C07C2/66 ,  C07C5/22 ,  C07C5/25 ,  C07C11/02 ,  C07C15/46 ,  C07C41/30 ,  C07C45/46 ,  C07C49/784 ,  C07C67/04 ,  C07C69/145 ,  C07C201/08 ,  C07C205/06 ,  C08G65/02 ,  C08G65/20 ,  B01J20/34 ,  B01J20/26

CPC classification number: B01J21/08 ,  B01J31/10 ,  B01J31/165 ,  B01J31/2419 ,  B01J31/4007 ,  B01J35/10 ,  B01J35/1019 ,  B01J35/1023 ,  B01J35/1038 ,  B01J35/1042 ,  B01J35/1047 ,  B01J35/1057 ,  B01J35/1061 ,  B01J35/1066 ,  B01J35/1071 ,  B01J35/109 ,  B01J2231/10 ,  B01J2231/323 ,  B01J2231/4205 ,  B01J2231/52 ,  B01J2231/54 ,  B01J2531/38 ,  B01J2531/821 ,  B01J2531/825 ,  B01J2531/842 ,  B01J2531/847 ,  C07C2/02 ,  C07C2/66 ,  C07C5/2266 ,  C07C5/2273 ,  C07C5/2562 ,  C07C41/30 ,  C07C45/46 ,  C07C67/04 ,  C07C201/08 ,  C07C2521/04 ,  C07C2521/06 ,  C07C2521/08 ,  C07C2521/12 ,  C07C2523/10 ,  C07C2523/14 ,  C07C2523/26 ,  C07C2523/28 ,  C07C2523/745 ,  C07C2531/08 ,  C07C2531/10 ,  C07C2531/20 ,  C07C2531/26 ,  C07C2531/34 ,  Y02P20/584 ,  C07C11/02 ,  C07C49/784 ,  C07C69/013 ,  C07C69/14 ,  C07C205/06 ,  C07C43/263

Abstract: Porous microcomposites have been prepared from perfluorinated ion-exchange polymer and metal oxides such as silica using the sol-gel process. Such microcomposites possess high surface area and exhibit extremely high catalytic activity.

公开(公告)号：US6139770A

公开(公告)日：2000-10-31

申请号：US857325

申请日：1997-05-16

Applicant: Kiyoshi Katsumoto ,  Ta Yen Ching ,  Joseph L. Goodrich ,  Drew Ve Speer

Inventor： Kiyoshi Katsumoto ,  Ta Yen Ching ,  Joseph L. Goodrich ,  Drew Ve Speer

IPC: A23L3/3463 ,  A23L3/3436 ,  B01J31/04 ,  B32B27/08 ,  B32B27/18 ,  B65D51/24 ,  B65D81/26 ,  C07C45/46 ,  C07C49/784 ,  C07C49/786 ,  C07C49/788 ,  C08K5/00 ,  C08K5/132 ,  C08L9/00 ,  C09K15/06 ,  C09K3/00

CPC classification number: C09K15/06 ,  A23L3/3436 ,  B32B27/08 ,  B65D81/266 ,  C07C45/46 ,  C07C49/784 ,  C07C49/788 ,  C08K5/0008 ,  C08K5/132

Abstract: An oxygen scavenging composition or system is provided comprising an oxygen scavenging material, a photoinitiator, and at least one catalyst effective in catalyzing an oxygen scavenging reaction, wherein the photoinitiator comprises a benzophenone derivative containing at least two benzophenone moieties. A film, a multi-phase composition, a multi-layer composition, a multi-layer film, an article comprising the oxygen scavenging composition, a method for preparing the oxygen scavenging composition, and a method for scavenging oxygen are also provided. Non-extractable benzophenone derivative photoinitiators and methods for preparing same are also provided.

Abstract translation: 提供了一种除氧组合物或系统，其包括除氧材料，光引发剂和至少一种有效催化除氧反应的催化剂，其中光引发剂包含含有至少两个二苯甲酮部分的二苯甲酮衍生物。 还提供了膜，多相组合物，多层组合物，多层膜，包含除氧组合物的制品，氧清除组合物的制备方法和清除氧气的方法。 还提供了不可萃取的二苯甲酮衍生物光引发剂及其制备方法。

公开(公告)号：US5576354A

公开(公告)日：1996-11-19

申请号：US463516

申请日：1995-06-05

Applicant: Andre Deflandre ,  Michel DuBois ,  Serge Forestier ,  Herve Richard

Inventor： Andre Deflandre ,  Michel DuBois ,  Serge Forestier ,  Herve Richard

IPC: A61K8/00 ,  A61K20060101 ,  A61K8/04 ,  A61K8/34 ,  A61K8/35 ,  A61K8/36 ,  A61K8/37 ,  A61K8/40 ,  A61K8/92 ,  A61K31/12 ,  A61K31/19 ,  A61Q17/04 ,  C07C49/784 ,  C07C69/618 ,  A61K7/40 ,  A61K7/42

CPC classification number: A61Q17/04 ,  A61K8/35 ,  A61K8/37 ,  A61K8/40 ,  A61K2800/52

Abstract: A photostable cosmetic screening composition and process for protection of the human epidermis against UV rays of wavelengths between 280 and 380 nm, the composition having, in a cosmetically acceptable vehicle containing at least one fatty phase, 1 to 5% by weight of a dibenzoylmethane derivative and at least 1% by weight of an alkyl .beta.-.beta.-diphenylacrylate or .alpha.-cyano-.beta.-.beta.-diphenylacrylate of formula (I), the mole ratio of the compound of formula (I) to the dibenzoylmethane derivative being not less than 0.8.

Abstract translation: 一种光稳定化妆品筛选组合物和用于保护人类表皮的抗紫外线波长在280和380nm之间的组合物，该组合物在含有至少一种脂肪相的化妆品可接受载体中含有1至5重量％的二苯甲酰甲烷衍生物 和至少1重量％的式（I）的β-β-二苯基丙烯酸烷基酯或α-氰基-β-β-二苯基丙烯酸酯，式（I）化合物与二苯甲酰甲烷衍生物的摩尔比不小于 0.8。