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    MICROFLUIDIC SYSTEM
    84.
    发明申请
    MICROFLUIDIC SYSTEM 有权
    微流体系

    公开(公告)号：US20100008834A1

    公开(公告)日：2010-01-14

    申请号：US11989177

    申请日：2006-07-24

    申请人： Astrid Lohf ,  Waldemar Wenzel

    发明人： Astrid Lohf ,  Waldemar Wenzel

    IPC分类号： B01J19/00 ,  B01F15/06

    CPC分类号： B01J19/0093 ,  B01F13/0059 ,  B01J2219/00783 ,  B01J2219/00873 ,  B01J2219/00952 ,  B01J2219/00961 ,  B01J2219/00963 ,  B01L3/5027 ,  B01L2200/08 ,  B01L2200/143

    摘要： There is described a microfluid system with a microchannel structure for the passage of fluids and a further channel structure separated from the microstructure by means of at least one separating wall for the passage of a heat transfer fluid. The risk of internal leakage in the microfluid system can be recognized in time, by separation of the microchannel structure from a cavity of at least one point by a further separating wall, said separating wall being at least locally weaker than the separating wall between the microchannel structure and the further channel structure and said cavity is connected to a detector device for detection of ingressing fluid.

    摘要翻译： 描述了具有用于流体通过的微通道结构的微流体系统和通过至少一个用于传热流体通过的分离壁与微结构分离的另一通道结构。 微流体系统中的内部泄漏的风险可以通过将微通道结构与至少一个点的空腔分开通过另外的分隔壁来及时识别，所述分隔壁至少局部地弱于微通道之间的分隔壁 结构和另外的通道结构，并且所述空腔连接到用于检测进入流体的检测器装置。

    Microfluidic System
    86.
    发明申请
    Microfluidic System 有权
    微流体系统

    公开(公告)号：US20090126504A1

    公开(公告)日：2009-05-21

    申请号：US11992803

    申请日：2006-09-28

    申请人： Astrid Lohf ,  Reinhold Schneeberger ,  Waldemar Wenzel

    发明人： Astrid Lohf ,  Reinhold Schneeberger ,  Waldemar Wenzel

    IPC分类号： G01F1/56 ,  G01L9/00

    CPC分类号： B01J19/0093 ,  B01J2219/0081 ,  B01J2219/00867 ,  B01J2219/00871 ,  B01J2219/00873 ,  B01J2219/00959 ,  B01J2219/00963 ,  B01J2219/00986 ,  B01L1/50 ,  B01L3/5027 ,  B01L99/00 ,  G01N2035/00277 ,  G01N2035/00326

    摘要： The microfluidic system is constituted of modules that comprise one microfluidic unit and one corresponding electric control unit each and that are retained on a rear panel unit next to each other in a row. To prevent the formation of accumulation of ignitable or toxic gas mixtures a fluid conduit for a rinsing fluid extends through the rear panel unit. Branches lead from said fluid conduit to the modules, and said branches flowing into respective distributor compartments that extend vertically across the module height in the modules. Said distributor compartments are delimited in relation to the interior of the respective module by a distributor panel that is provide with openings. The interior of the respective module comprises, on its lower or rear surface, an exit opening for the rinsing fluid.

    摘要翻译： 微流体系统由包括一个微流体单元和一个相应的电气控制单元的模块构成，并且彼此相邻地保持在后面板单元上。 为了防止可燃或有毒气体混合物的堆积的形成，用于冲洗流体的流体导管延伸穿过后面板单元。 分支从所述流体导管引导到模块，并且所述分支流入相应的分配器隔间，其横跨模块中的模块高度垂直延伸。 所述分配器隔室通过提供开口的分配器面板相对于相应模块的内部限定。 相应模块的内部在其下表面或后表面上包括用于冲洗流体的出口。

    Inlet channel volume in a reactor
    89.
    发明申请
    Inlet channel volume in a reactor 审中-公开
    反应器中的入口通道体积

    公开(公告)号：US20070036690A1

    公开(公告)日：2007-02-15

    申请号：US11146922

    申请日：2005-06-07

    申请人： Scott Miller ,  A. Russo ,  Sean LeBlanc ,  Timothy Johnson

    发明人： Scott Miller ,  A. Russo ,  Sean LeBlanc ,  Timothy Johnson

    IPC分类号： B01J19/00 ,  B01L3/00

    CPC分类号： B01J19/0093 ,  B01J2219/00837 ,  B01J2219/00862 ,  B01J2219/00869 ,  B01J2219/00907 ,  B01J2219/00952 ,  B01J2219/00963 ,  B01J2219/0097 ,  B01L3/5025 ,  B01L3/502715 ,  B01L3/502746 ,  B01L2200/027 ,  B01L2200/0668 ,  B01L2200/0684 ,  B01L2300/0816 ,  B01L2300/0825 ,  B01L2300/0877 ,  B01L2300/0887 ,  B01L2300/10 ,  B01L2400/0457 ,  B01L2400/0688 ,  B01L2400/086

    摘要： The present invention generally relates to chemical, biological, and/or biochemical reactor microreactors and other reaction systems such as microreactor systems, as well as systems and methods for constructing and using such devices. In one aspect, a reactor on a chip has a container in fluid communication with a channel, and the channel is in fluid communication with a port for connecting the container to a source of fluid to be introduced into the container. The container can be very small, for example, with a volume of less than about 2 milliliters, and the fluid channel can have a channel volume of less than 1.5 percent of the container volume. According to another aspect, the combined volume of the port volume and the channel volume can be less than about 10 percent of the container volume. Such a configuration may increase the percentage of added fluid that reaches the container. In fed-batch operations, species may be added and removed via the same channel so that a gas headspace can be maintained within the reactor.

    摘要翻译： 本发明一般涉及化学，生物和/或生化反应器微反应器和其它反应系统，例如微反应器系统，以及用于构建和使用这些装置的系统和方法。 在一个方面，芯片上的反应器具有与通道流体连通的容器，并且通道与用于将容器连接到待引入容器的流体源的端口流体连通。 容器可以非常小，例如，体积小于约2毫升，并且流体通道可以具有小于容器体积的1.5％的通道体积。 根据另一方面，端口容积和通道容积的组合体积可以小于容器体积的约10％。 这种构造可以增加到达容器的添加流体的百分比。 在补料分批操作中，可以通过相同的通道添加和除去物质，使得可以在反应器内保持气体顶部空间。