公开(公告)号：US12019083B2

公开(公告)日：2024-06-25

申请号：US17834165

申请日：2022-06-07

申请人： EMULATE, Inc.

发明人： Josiah Sliz ,  Daniel Levner ,  Brian Zuckerman ,  Norman Wen ,  Jonathan Rubins ,  Tanvi Shroff ,  Christopher David Hinojosa ,  Grace Ahn ,  Victor Antontsev ,  Jefferson Puerta ,  David Conegliano ,  S. Jordan Kerns

IPC分类号： G01N35/00 ,  B01L3/00 ,  C12Q3/00 ,  G01N15/06 ,  G01N33/50

CPC分类号： G01N35/00584 ,  B01L3/502761 ,  C12Q3/00 ,  G01N15/06 ,  G01N33/5008 ,  B01L3/502707 ,  B01L2200/0647 ,  B01L2200/148 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/10 ,  B01L2400/0406 ,  G01N2035/00544 ,  G01N2035/0097

摘要： The present invention is related to the field of microfluidics and compound distribution within microfluidic devices and their associated systems. In one embodiment, present invention aims to solve the problem of molecule and compound absorbency into the materials making up laboratory equipment, microfluidic devices and their related infrastructure, without unduly restricting gas transport within microfluidic devices.

公开(公告)号：US20240091777A1

公开(公告)日：2024-03-21

申请号：US18468941

申请日：2023-09-18

申请人： Parhelia Biosciences Corporation

发明人： Nikolay SAMUSIK

IPC分类号： B01L3/00

CPC分类号： B01L3/5085 ,  B01L2300/10 ,  B01L2300/1883

摘要： A histological container for histological samples is provided with a removable humidity control lid with portals for access into the container. The lid creates a humidified zone across the lid portals to allow processing steps inside the container while minimizing variations in the container humidity. A cover can be placed over the container for thermal control inside the container. The cover includes a top with portals aligned with the lid portals for access through the cover and top to inside the container. The cover can include a shutter slidably interfaced with the top. The shutter can include shutter portals selectively aligned with the top portals. Slidable alignment of the shutter portals with the top portals allows access to inside the container. Slidable nonalignment of the shutter portals with the top portals restricts access, essentially closing the container to control temperature levels and other ambient conditions inside the container.

公开(公告)号：US20180320913A1

公开(公告)日：2018-11-08

申请号：US15735016

申请日：2016-06-08

申请人： KOH YOUNG TECHNOLOGY INC.

发明人： Jang Il SER ,  Hyo Bin KIM ,  Yong Seung SHIN ,  Hong Ki KIM ,  Ho Jun LEE

IPC分类号： F24F6/12 ,  G01B11/25

CPC分类号： F24F6/12 ,  B01F3/022 ,  B01F5/0485 ,  B01L1/04 ,  B01L2200/147 ,  B01L2300/024 ,  B01L2300/10 ,  B01L2300/18 ,  B01L2300/1894 ,  F25B21/02 ,  F25B41/00 ,  F28C3/08 ,  G01B11/25 ,  G01B11/2513 ,  G01N21/958 ,  G01N2021/845

摘要： A humid air forming device, which cools an object to be measured to a predetermined temperature, and which sprays humid air having a predetermined temperature to the cooled object to be measured, thereby forming moisture particles on the surface of the object to be measured, and a measurement system including the same. The humid air forming device includes a cooling unit that cools the object to be measured to a first temperature or lower; and a humid air supply unit that forms humid air having a second temperature, which is higher than the first temperature, and spraying the humid air toward the surface of the cooled object to be measured, thereby forming moisture particles on the surface of the cooled object to be measured.

公开(公告)号：US20180264459A1

公开(公告)日：2018-09-20

申请号：US15982845

申请日：2018-05-17

申请人： PHC HOLDINGS CORPORATION

发明人： Ritaro OGUMA ,  Shinji SUGIMOTO

IPC分类号： B01L1/02 ,  B08B15/02

CPC分类号： B01L1/02 ,  B01L1/00 ,  B01L2200/08 ,  B01L2200/141 ,  B01L2300/10 ,  B01L2300/14 ,  B08B15/023 ,  F24F3/1607

摘要： A biological safety cabinet or the like according to an embodiment of the present disclosure includes: a bottom plate 4 provided in a body case 2; and a flexible portion provided to a front shutter protector 6 that is provided to a lower end of the front shutter 5, and is capable of ensure reliability by reducing the load of the front shutter such that outside air is drawn into the body case 2 through a gap 15 formed in a contact portion between the flexible portion 13 and the bottom plate 4.

公开(公告)号：US20180245133A1

公开(公告)日：2018-08-30

申请号：US15965155

申请日：2018-04-27

申请人： The Board of Trustees of the Leland Stanford Junior University

发明人： Matthew T. O'Keefe ,  Pamela K. Foreman

IPC分类号： C12Q1/686 ,  C12Q1/6883

CPC分类号： C12Q1/686 ,  B01F13/0059 ,  B01F13/0071 ,  B01F13/0084 ,  B01F15/0201 ,  B01F15/0232 ,  B01F2215/0431 ,  B01J2219/00286 ,  B01J2219/00317 ,  B01J2219/0072 ,  B01J2219/00722 ,  B01J2219/0074 ,  B01L3/5025 ,  B01L3/50857 ,  B01L3/5088 ,  B01L2200/0642 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/087 ,  B01L2300/10 ,  B01L2300/165 ,  B01L2400/0688 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  C40B40/06 ,  C40B60/14 ,  H01J49/0418 ,  Y02P20/582

摘要： Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

公开(公告)号：US09975124B2

公开(公告)日：2018-05-22

申请号：US14415858

申请日：2013-07-24

申请人： Genevac Limited

发明人： Symon Rose ,  Robert Hugh Douglas Darrington ,  John Michael Poole ,  Graham Broadbent ,  Donald Roger Lee-Smith ,  Richard John Smith

IPC分类号： B01L3/00 ,  B01L9/00 ,  B01L3/06

CPC分类号： B01L3/50825 ,  B01L3/06 ,  B01L3/5025 ,  B01L3/50853 ,  B01L9/00 ,  B01L2200/028 ,  B01L2200/0678 ,  B01L2200/0694 ,  B01L2300/047 ,  B01L2300/048 ,  B01L2300/10 ,  B01L2400/0409

摘要： Apparatus and methods are provided relating to evaporation of solvents from samples and to prolonging the time taken to carry out an evaporation procedure. A cap for engaging with an open end of a sample container comprises an engaging surface for engaging with the open end, and a body portion which extends over the open end. The body portion is preformed to define an opening which provides a fluid pathway between the open end of the container and the surroundings of the container, such that the cap impedes vapor flow from a sample in the container to the surroundings of the container. A holder for receiving a plurality of such caps is also provided and a method of evaporating a solvent from a sample in a sample container is described.

公开(公告)号：US20180117589A1

公开(公告)日：2018-05-03

申请号：US15857754

申请日：2017-12-29

申请人： University of Maryland, College Park

发明人： Ian M. White ,  Srinivasa Raghavan ,  KunaI R. Pandit

IPC分类号： B01L3/00

CPC分类号： B01L3/502715 ,  B01L3/502784 ,  B01L2200/0621 ,  B01L2200/0642 ,  B01L2200/0673 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0858 ,  B01L2300/0864 ,  B01L2300/088 ,  B01L2300/10 ,  B01L2300/14 ,  B01L2300/18 ,  B01L2400/0487 ,  B01L2400/0666 ,  B01L2400/0688

摘要： The invention relates to a method and system for generating droplets of an aqueous solution on a microfluidic chip with an air continuous phase. Specifically, the droplet generator according to the present invention is integrated into a microfluidic chip to generate and introduce droplets of an aqueous solution into the microfluidic chip. The droplets travelling in a network of chip channels may be captured in on-chip traps in a manner defined by hydrodynamic resistances of chip channels. A biological reaction may be performed on a droplet trapped on the microfluidic chip.

公开(公告)号：US20180029033A1

公开(公告)日：2018-02-01

申请号：US15660616

申请日：2017-07-26

申请人： Ancera Corp.

发明人： Hur KOSER ,  G. Thomas ROTH ,  William M. SUTTER

IPC分类号： B01L3/00 ,  B07B1/46 ,  B03C1/32 ,  G01N15/10 ,  B01D19/00

CPC分类号： B01L3/502707 ,  B01D19/0031 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2300/0627 ,  B01L2300/0681 ,  B01L2300/10 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/0622 ,  B01L2400/082 ,  B03C1/0335 ,  B03C1/288 ,  B03C1/32 ,  B03C2201/18 ,  B03C2201/20 ,  B03C2201/26 ,  B07B1/4636 ,  G01N15/1031 ,  G01N15/1056 ,  G01N21/6452 ,  G01N35/1097 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1081

摘要： The disclosed embodiments relate to method, system and apparatus for assay testing. In an exemplary embodiment, the disclosure relates to a cartridge for testing an assay. The cartridge includes a sample reservoir to receive a mixture of a plurality of target particles and a ferrofluidic solution; a capture region formed on the cartridge; a fluidic channel to communicate the mixture between the sample reservoir and the capture region; a magnetic ferrofluidic solution positioned inside the fluidic channel; and at least one pneumatic valve to communicate a quantity of the mixture from the sample reservoir. The magnetic ferrofluidic solution is excitable in response to an externally applied electromagnetic field to affect the ferrofluidic solution in the mixture.

公开(公告)号：US20170232434A1

公开(公告)日：2017-08-17

申请号：US15501049

申请日：2015-04-07

申请人： AIRTECK JAPAN, LTD. ,  JAPAN TISSUE ENGINEERING CO., LTD.

发明人： Hiroshi GOTO ,  Yosuke OTSUKA ,  Shinya HIRASAWA ,  Ken-ichiro HATA ,  Yukio MORI ,  Makoto SUGIURA

IPC分类号： B01L1/02

CPC分类号： B01L1/025 ,  B01L1/04 ,  B01L2300/0681 ,  B01L2300/10 ,  B08B15/023 ,  B25H1/20 ,  F24F7/06

摘要： A safety cabinet has a second operation chamber in a first operation chamber and into which clean air is supplied, a second suction opening for sucking in air in the second operation chamber and a portion of the air in the first operation chamber, and a second operation opening part that is provided facing a first operation opening part and communicates the second operation chamber with the first operation chamber. Airflow containment (air barrier) is doubled with respect to the outside of a safety cabinet. In cases where decontamination and disinfection operations are carried out according to the changeover procedures, intensive decontamination and disinfection of the second operation chamber is sufficient, and decontamination and disinfection of the first operation chamber is hardly required. Decontamination and disinfection operations in the changeover procedures and the like can be carried out in a greatly reduced time.

公开(公告)号：US20170128934A1

公开(公告)日：2017-05-11

申请号：US15345079

申请日：2016-11-07

申请人： NEOTERYX, LLC

发明人： Stuart A. KUSHON ,  Gene ZAMBA ,  James Byron RUDGE ,  Carolyn JARING

IPC分类号： B01L3/00 ,  B01D15/10 ,  B01D15/26 ,  A61B5/15 ,  G01N1/34

CPC分类号： B01L3/5023 ,  A61B5/150022 ,  A61B5/150061 ,  A61B5/150099 ,  A61B5/150221 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150343 ,  A61B5/150755 ,  B01D15/10 ,  B01D15/26 ,  B01L3/502 ,  B01L3/5029 ,  B01L2200/0605 ,  B01L2200/0631 ,  B01L2200/0678 ,  B01L2200/0689 ,  B01L2300/021 ,  B01L2300/044 ,  B01L2300/069 ,  B01L2300/0832 ,  B01L2300/10 ,  B01L2400/0406 ,  B01L2400/049 ,  G01N1/34 ,  G01N33/491

摘要： The present invention discloses a plasma extraction device for generating fixed, predetermined quantity of plasma and for dry-transport of obtained plasma for automated assay. Plasma extraction device includes a plasma extractor assembly comprising an absorbent probe that wicks a predetermined volume of a liquid sample from a liquid source, a separator that generates plasma from the wicked liquid sample, and an absorbent reservoir that stores fixed, predetermined quantity of the generated plasma for dry-transport and automated assay thereof.