公开(公告)号：US20170232434A1

公开(公告)日：2017-08-17

申请号：US15501049

申请日：2015-04-07

申请人： AIRTECK JAPAN, LTD. ,  JAPAN TISSUE ENGINEERING CO., LTD.

发明人： Hiroshi GOTO ,  Yosuke OTSUKA ,  Shinya HIRASAWA ,  Ken-ichiro HATA ,  Yukio MORI ,  Makoto SUGIURA

IPC分类号： B01L1/02

CPC分类号： B01L1/025 ,  B01L1/04 ,  B01L2300/0681 ,  B01L2300/10 ,  B08B15/023 ,  B25H1/20 ,  F24F7/06

摘要： A safety cabinet has a second operation chamber in a first operation chamber and into which clean air is supplied, a second suction opening for sucking in air in the second operation chamber and a portion of the air in the first operation chamber, and a second operation opening part that is provided facing a first operation opening part and communicates the second operation chamber with the first operation chamber. Airflow containment (air barrier) is doubled with respect to the outside of a safety cabinet. In cases where decontamination and disinfection operations are carried out according to the changeover procedures, intensive decontamination and disinfection of the second operation chamber is sufficient, and decontamination and disinfection of the first operation chamber is hardly required. Decontamination and disinfection operations in the changeover procedures and the like can be carried out in a greatly reduced time.

公开(公告)号：US20140178990A1

公开(公告)日：2014-06-26

申请号：US14163371

申请日：2014-01-24

申请人： JAPAN TISSUE ENGINEERING CO., LTD. ,  TOAGOSEI CO. LTD.

发明人： Tetsuhiko YOSHIDA ,  Nahoko KOBAYASHI ,  Mikio NIWA ,  Chikara SHINOHARA ,  Masatoki WATANABE ,  Ken-ichiro HATA

IPC分类号： C12N5/0775 ,  C07K7/08 ,  C07K7/06 ,  C07K14/00

CPC分类号： C12N5/0662 ,  A61K38/00 ,  C07K7/06 ,  C07K7/08 ,  C07K14/001 ,  C07K14/475 ,  C07K2319/10 ,  C07K2319/21 ,  C07K2319/23 ,  C12N5/0018 ,  C12N2501/998

摘要： A method for manufacturing at least one kind of eukaryotic cells or a biosynthetic substance derived from the eukaryotic cells by proliferating the cells, which includes preparing an artificially synthesized peptide for promoting proliferation of the at least one kind of eukaryotic cells, incubating the eukaryotic cells in a culture medium, and adding the synthesized peptide at least once to the culture medium during the incubation process. The synthesized peptide includes an amino acid sequence selected from SEQ ID NOS: 1 to 18, and an amino acid sequence selected from SEQ ID NOS: 19 to 97.

摘要翻译： 一种用于通过增殖细胞来制造至少一种真核细胞或源自真核细胞的生物合成物质的方法，其包括制备用于促进至少一种真核细胞增殖的人造合成肽，将真核细胞孵育 培养基，并且在孵育过程中将合成的肽至少一次加入到培养基中。 合成的肽包括选自SEQ ID NO：1至18的氨基酸序列和选自SEQ ID NO：19至97的氨基酸序列。

公开(公告)号：US20160298867A1

公开(公告)日：2016-10-13

申请号：US14914796

申请日：2014-10-23

申请人： JAPAN TISSUE ENGINEERING CO., LTD.

发明人： Ken-ichiro HATA ,  Makoto SUGIURA

IPC分类号： F24F7/08 ,  B01L1/00 ,  B01L9/00 ,  F24F9/00

CPC分类号： F24F7/08 ,  B01L1/00 ,  B01L1/04 ,  B01L9/06 ,  B01L9/543 ,  B01L2200/141 ,  C12M39/00 ,  F24F3/1607 ,  F24F9/00

摘要： A work area is disposed in a conveyance path for cells and has an inlet and an outlet, with a downflow air curtain provided at least at the inlet and the outlet. A conveyor repeatedly performs an operation that moves a placement surface having a culture vessel thereon from the inlet side into the area, moves the placement surface from the outlet side to the outside of the area, and, subsequently, moves back the placement surface to the inlet side. The cleaning device cleans the placement surface during the period from when the conveyor in the work area moves the placement surface to the outside of the area until the conveyor moves back the placement surface to the inlet side of the area.

摘要翻译： 工作区域设置在用于单元的输送路径中，并且具有入口和出口，至少设置在入口和出口处具有下流式气帘。 输送机重复执行将入口侧的培养容器的放置面从入口侧移动到该区域的动作，将放置面从出口侧移动到该区域的外侧，并且随后将放置面向后移动到 入口侧。 在从工作区域中的传送带将放置表面移动到该区域的外部的时间段期间，清洁装置清洁放置表面，直到传送器将放置表面移回到该区域的入口侧。

公开(公告)号：US20150290359A1

公开(公告)日：2015-10-15

申请号：US14751511

申请日：2015-06-26

申请人： FUJIFILM CORPORATION ,  JAPAN TISSUE ENGINEERING CO., LTD.

发明人： Kazutaka OGIWARA ,  Kazuhiro YAMAGUCHI ,  Tasuku SASAKI ,  Eiko GOTO ,  Katsura SUGAWARA ,  Ken-ichiro HATA

IPC分类号： A61L27/22 ,  A61F2/10 ,  A61L27/58 ,  A61L27/60 ,  A61L27/56

CPC分类号： A61L27/222 ,  A61F2/105 ,  A61F2210/0076 ,  A61L27/56 ,  A61L27/58 ,  A61L27/60 ,  A61L2430/34

摘要： Artificial dermis for transplantation includes a wound contact layer that includes a porous sheet consisting of a biodegradable material, the porous sheet satisfying the following Equation, Equation: X2/X1≦0.8. In the porous sheet, when a line parallel to a wound contact face and a line perpendicular to a wound contact face of equal length are drawn, X1 represents a number of points of intersection between the line parallel to the wound contact face and pore walls; and X2 represents a number of points of intersection between the line perpendicular to the wound contact face and pore walls.

摘要翻译： 用于移植的人造真皮包括伤口接触层，其包括由可生物降解材料组成的多孔片，满足以下等式的多孔片，等式：X2 / X1＆N1; 0.8。 在多孔片材中，当绘制平行于伤口接触面的线和垂直于相同长度的伤口接触面的线时，X1表示平行于伤口接触面的线与孔壁之间的交点数; X2表示与伤口接触面垂直的线与孔壁的交点数。