公开(公告)号：US20230407412A1

公开(公告)日：2023-12-21

申请号：US18251528

申请日：2021-11-04

Applicant: Becton, Dickinson and Company

Inventor： Qiufeng Zhang ,  Manliang FU ,  Chuanhui Zhang

IPC: C12Q1/689 ,  C12Q1/686

CPC classification number: C12Q1/689 ,  C12Q1/686 ,  C12Q2600/16

Abstract: Methods and compositions for detection of common bacterial pathogens causing respiratory infections are disclosed herein. In some embodiments, the presence or absence of Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Moraxella (Branhamella) catarrhalis, Neisseria meningitides, and/or Klebsiella pneumoniae in a sample is determined using multiplex nucleic acid-based testing methods.

公开(公告)号：US11845919B2

公开(公告)日：2023-12-19

申请号：US15573266

申请日：2016-05-13

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Mei Yang-Woytowitz ,  Song Shi ,  Xiaofei Chang ,  James Y. Zhou ,  Michael A. Brasch

IPC: C12M1/24 ,  C12M1/34 ,  C12N5/078 ,  C12M1/00

CPC classification number: C12M23/08 ,  C12M23/00 ,  C12M41/46 ,  C12N5/0634 ,  C12N2501/999

Abstract: A container for culturing a blood sample. The container has a reservoir that is no larger than about 40 ml in volume with culture media therein varying in amount by volume 0.5 ml to about 20 ml. The container is adapted to receive a blood sample drawn from a patient, wherein the blood volume is about 1 ml to about 20 ml. In some embodiments the ratio of blood volume to culture media volume is about 2:1 to about 1:2 and the volume of blood does not exceed about 10 ml. In some embodiments, the media is lytic media. A method for using the container to culture a blood sample is also contemplated. In such method, the container is inoculated with the blood sample. In certain embodiments, the volume of the blood sample does not exceed 10 mls.

公开(公告)号：US20230397860A1

公开(公告)日：2023-12-14

申请号：US18033967

申请日：2021-11-09

Applicant: Becton, Dickinson and Company

Inventor： Yueqiang Xue ,  Bo Yan ,  Jonathan Karl Burkholz ,  Mohankumar Natesan ,  Kiat Jin Cheng

IPC: A61B5/15 ,  A61M25/06

CPC classification number: A61B5/150992 ,  A61M25/0606 ,  A61B5/15003

Abstract: A catheter system may include a catheter assembly, which may include a catheter adapter and a catheter extending distally from the catheter adapter. The catheter system may include a needle assembly, which may include a needle hub and an introducer needle extending distally from the needle hub. The introducer needle may extend through the catheter. The needle assembly may also include an extension tube, which may include a distal end integrated with the needle hub and a proximal end integrated with a cannula hub. A cannula may extend proximally from the cannula hub. An elastomeric sheath may be coupled to the cannula hub, and a proximal end of the cannula may be enveloped within the elastomeric sheath. In response to the blood collection tube pushing the elastomeric sheath distally, the cannula may pierce the elastomeric sheath, and the cannula may insert into the blood collection tube.

公开(公告)号：US11840719B2

公开(公告)日：2023-12-12

申请号：US16926926

申请日：2020-07-13

Applicant: BECTON DICKINSON AND COMPANY

Inventor： Mei Yang-Woytowitz ,  Brent Pohl ,  Gary F. Hershner ,  Dwight Livingston ,  Eric Ursprung ,  Gerard Lotz ,  Kevin Bailey ,  Ammon David Lentz ,  Michael A. Brasch ,  Ming-hsiung Yeh ,  Patrick Shawn Beaty ,  Charles C. Yu ,  Timothy M. Wiles ,  Liping Feng ,  Ben Turng ,  Xiaofei Chang ,  Patrick R. Murray

IPC: C12Q1/02 ,  A61J1/05 ,  C12M1/24 ,  A61J1/14 ,  A61J1/20 ,  B01L3/00 ,  C12C1/02 ,  C12M1/00

CPC classification number: C12Q1/02 ,  A61J1/05 ,  A61J1/1406 ,  A61J1/1418 ,  A61J1/2006 ,  A61J1/2089 ,  A61J1/2093 ,  B01L3/502 ,  C12C1/02 ,  C12M23/08 ,  C12M23/38 ,  C12M29/00 ,  B01L2200/0621 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/047 ,  B01L2300/087 ,  B01L2300/0832 ,  G01N2800/26

Abstract: An apparatus and associated methods of use for a controlled combination of reagents is disclosed. The apparatus includes a vessel 400, a vessel insert 220, and a cap element 200. The vessel 400 has a body portion 410 for receiving a biological sample. The vessel insert 220 receives at least one reagent therein. Preferably, the vessel insert 220 is received in a portion 420 of the vessel 400. The cap element 200 is attached to the vessel 400 to secure the vessel insert 220 in the vessel 400. During use, the vessel insert 220 is adapted to release its contents when the biological sample is introduced into the body portion 410 of the vessel 400 upon application of an intermixing force to the vessel insert 220. A variety of intermixing forces may be applied, depending upon the embodiment of the present invention and its associated methods of use.

公开(公告)号：US20230393047A1

公开(公告)日：2023-12-07

申请号：US18203500

申请日：2023-05-30

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Kyle Dembski ,  Pierce Norton

IPC: G01N15/14

CPC classification number: G01N15/1404 ,  G01N15/1459 ,  G01N2015/1461 ,  G01N2015/1409 ,  G01N2015/0065

Abstract: Fluidic resistance units are provided. Fluidic resistance units of interest include a plurality of valves and a plurality of resistors, where each resistor in the plurality of resistors is fluidically coupled to and co-located with a different valve in the plurality of valves. In one embodiment, fluidic resistance units include an inlet for receiving fluid, a valve line fluidically coupled to the inlet, a resistor line fluidically coupled to the inlet, a plurality of connectors fluidically coupling the valve line to the resistor line, and an outlet for emitting fluid. Valve lines of interest include a series of fluidically coupled valves, and resistor lines of interest include a series of fluidically coupled resistors. Methods and flow cytometers involving the subject fluidic resistance units are also provided.

公开(公告)号：US20230390505A1

公开(公告)日：2023-12-07

申请号：US18034114

申请日：2021-10-27

Applicant: Becton, Dickinson and Company

Inventor： Siddarth K. Shevgoor ,  Balaji Sadasivam ,  Nicole Jean DiStefano

IPC: A61M5/32 ,  A61M5/178 ,  A61M5/34

CPC classification number: A61M5/3291 ,  A61M5/1782 ,  A61M5/345

Abstract: A membrane for a closed system transfer device includes a body having a first end and a second end positioned opposite the first end, the body defining a passageway extending from the first end of the body to a position intermediate the first end of the body and the second end of the body, and a guide member positioned within the passageway of the body. The guide member having a first end and a second end positioned opposite the first end, with the guide member having a guide surface configured to engage a needle positioned within the passageway of the body.

公开(公告)号：US20230390503A1

公开(公告)日：2023-12-07

申请号：US18248031

申请日：2021-10-04

Applicant: Becton, Dickinson and Company

Inventor： Christopher MAUL ,  Christopher GILDEA ,  Andrew METTERS

IPC: A61M5/32

CPC classification number: A61M5/3286 ,  A61M2205/0238

Abstract: A medication delivery device is provided with a stainless steel needle or cannula where the patient end of the needle or cannula has a protective outer layer over the surface of the needle or cannula. The protective outer layer has a thickness and is oriented to prevent or minimize contact of the tissue of the patient with the stainless steel to prevent or inhibit allergic reactions by the tissue contact with the nickel in the stainless steel. The protective outer layer can be a metal coating of a non-allergenic metal, such as gold, or other coating material that is able to cover the exposed surface of the needle to prevent direct contact of the stainless steel with the patient.

公开(公告)号：US11826557B2

公开(公告)日：2023-11-28

申请号：US17192774

申请日：2021-03-04

Applicant: Becton, Dickinson and Company

Inventor： Shaun Staley ,  Weston O. Whitaker ,  Jon Larsen

IPC: A61M5/38 ,  A61M5/14 ,  A61M5/36 ,  A61M5/44 ,  B01D53/62

CPC classification number: A61M5/38 ,  A61M5/1411 ,  A61M5/36 ,  A61M5/44 ,  B01D53/62 ,  A61M5/385

Abstract: An intravenous delivery system may have a liquid source containing a liquid, tubing, and an anti-run-dry membrane positioned such that the liquid, flowing form the liquid source to the tubing, passes through the anti-run-dry membrane. The anti-run-dry membrane may have a plurality of pores through which the liquid flows, and may be formed of a hydrophilic material that resists passage of air through the pores. The intravenous delivery system may further have a bubble point raising component that raises the bubble point of the anti-run-dry membrane. The bubble point raising component may, in some embodiments, be a high surface energy coating or additive.

公开(公告)号：US11826522B2

公开(公告)日：2023-11-28

申请号：US15604244

申请日：2017-05-24

Applicant: Becton, Dickinson and Company

Inventor： Jonathan Karl Burkholz ,  Siddarth Shevgoor ,  Edward G. Henderson

IPC: A61M25/01 ,  A61B34/20 ,  A61B8/00 ,  A61B5/06 ,  A61B8/08 ,  A61M25/02 ,  A61M25/06 ,  A61M25/09 ,  A61M39/10

CPC classification number: A61M25/0127 ,  A61B5/062 ,  A61B8/0841 ,  A61B8/4254 ,  A61B34/20 ,  A61M25/0102 ,  A61M25/02 ,  A61M25/065 ,  A61M25/0618 ,  A61M25/09041 ,  A61M39/10 ,  A61B2034/2051 ,  A61M2025/0266 ,  A61M2039/1077

Abstract: Systems, methods and devices are described including a medical device subassembly including a magnetic feature. Systems include such a catheter adapter subassembly or needle subassembly or guidewire introducer subassembly and a wire including a magnetic feature, and relative movement of the catheter adapter subassembly or needle subassembly or guidewire introducer subassembly and the wire can be determined using an magnetometer.

公开(公告)号：US11826515B2

公开(公告)日：2023-11-28

申请号：US16229190

申请日：2018-12-21

Applicant: Becton, Dickinson and Company

Inventor： Ralph Lee Sonderegger ,  Weston Harding

IPC: A61M25/00 ,  A61M5/158 ,  B29C45/00 ,  A61M25/06 ,  B29C45/16 ,  B29L31/00

CPC classification number: A61M25/001 ,  A61M5/158 ,  A61M25/0009 ,  A61M25/0606 ,  B29C45/00 ,  A61M25/0097 ,  A61M2005/1581 ,  A61M2005/1585 ,  A61M2005/1587 ,  A61M2207/00 ,  B29C45/1615 ,  B29L2031/7542

Abstract: A one-piece catheter (30) and manufacturing method therefor are disclosed. The catheter (30) includes a catheter tube (33) and an adapter (31). The catheter catheter tube (33) includes a tip (331) at one end and an end portion (332) at another other end. The adapter (31) can be configured for receiving a septum (402). The adapter (31) includes a narrow opening. The end portion (332) of the catheter tube (33) is connected to the adapter (31) at the narrow opening for fluid communication between the catheter tube (33) and the adapter (31). The catheter tube (33) and adapter (31) are formed as a one-piece element that is preferably injection molded in a single-shot process. Additional elements, such as one or more retention tabs (313) for attaching to a base can be formed on the catheter (30). The one-piece catheter (30) can be made by a single-shot injection molding process. Additional structures, such as a base can be attached to the catheter (30) by a second-shot injection molding process.