公开(公告)号：US20180080824A1

公开(公告)日：2018-03-22

申请号：US15607087

申请日：2017-05-26

Applicant: University of Hawaii

Inventor： Paul Lucey

IPC: G01J3/26 ,  G01J3/14 ,  G01J3/453

Abstract: A spatial Fourier transform spectrometer is disclosed. The Fourier transform spectrometer includes a Fabry-Perot interferometer with first and second optical surfaces. The gap between the first and second optical surfaces spatially varies in a direction that is orthogonal to the optical axis of the Fourier transform spectrometer. The Fabry-Perot interferometer creates an interference pattern from input light. An image of the interference pattern is captured by a detector, which is communicatively coupled to a processor. The processor is configured to process the interference pattern image to determine information about the spectral content of the input light.

公开(公告)号：US09861286B1

公开(公告)日：2018-01-09

申请号：US15686198

申请日：2017-08-25

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  A61B5/00 ,  G01N33/49 ,  G01N33/44 ,  G01N33/15 ,  G01N33/02 ,  G01N21/88 ,  G01N21/3563 ,  G01N21/359 ,  G01J3/453 ,  A61B5/145 ,  A61B5/1455 ,  H01S3/30 ,  G01N21/39 ,  G01M3/38 ,  G01J3/28 ,  G01J3/10 ,  G01J3/18 ,  G01J3/14

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device for use with a smart phone or tablet includes LEDs for measuring physiological parameters by modulating the LEDs and generating a near-infrared multi-wavelength optical beam. At least one LED emits at a first wavelength having a first penetration depth and at least another LED emits at a second wavelength having a second penetration depth into tissue. The device includes lenses that deliver the optical beam to the tissue, which reflects the first and second wavelengths. A receiver is configured to capture light while the LEDs are off and while at least one of the LEDs is on and to difference corresponding signals to improve a signal-to-noise ratio of the optical beam reflected from the tissue. The signal-to-noise ratio is further increased by increasing light intensity of at least one of the LEDs. The device generates an output signal representing a non-invasive measurement on blood within the tissue.

公开(公告)号：US20170350763A1

公开(公告)日：2017-12-07

申请号：US15524119

申请日：2015-11-05

Applicant: Carl Zeiss Microscopy GmbH

Inventor： David SHAFER ,  Tiemo ANHUT ,  Matthias WALD

IPC: G01J3/44 ,  G02B21/36 ,  G01J3/14 ,  G02B27/00 ,  G01N21/64 ,  G01J3/18 ,  G01J3/02 ,  G02B21/16

CPC classification number: G01J3/4406 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/14 ,  G01J3/18 ,  G01J3/36 ,  G01N21/6458 ,  G01N2021/6421 ,  G01N2201/068 ,  G02B21/0064 ,  G02B21/0076 ,  G02B21/16 ,  G02B21/361 ,  G02B27/0025 ,  G02B27/1013 ,  G02B27/126

Abstract: A detection device (113) for a microscope comprises a dispersive element (211) in the beam path (290) of light and a selection element (212). The selection element (212) separates a beam path (291) of a spectral portion of the light from the beam path (290) of the light. The detector device (113) furthermore comprises a focusing optical unit (213) configured to focus the beam path (291) of the spectral portion of the light onto a sensor (214). By way of example, the microscope may be a confocal microscope.

公开(公告)号：US09726541B2

公开(公告)日：2017-08-08

申请号：US14975792

申请日：2015-12-20

Applicant: AB Elektronik Sachsen GmbH

Inventor： Aldo Bojarski ,  Klaus Erler ,  Katrin Künzelmann ,  Andre Legner ,  Paul Smith ,  Tobby Straβberger

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/14 ,  G01J3/10 ,  G01N21/41 ,  G01N21/27

CPC classification number: G01J3/2803 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/14 ,  G01N21/27 ,  G01N21/4133 ,  G01N2201/0221 ,  G01N2201/0627

Abstract: A sensor for monitoring a medium has an electromagnetic radiation source, mirrors, and a detector for electromagnetic radiation arranged inside a cup-shaped housing part. The cup-shaped part has flat, angularly arranged wall areas defining a cavity in which, outside of the housing, the medium is contained. The flat wall areas are transparent for electromagnetic radiation and arranged in the beam path from the electromagnetic radiation source to the detector so that the electromagnetic radiation passes through first wall, medium in the cavity, and second wall. The first and second wall areas and the medium form a refracting prism. A cover closes off the cup-shaped part so that electromagnetic radiation source, detector, and mirrors are enclosed in the housing. A data processing system is connected to electromagnetic radiation source and detector so that electromagnetic radiation of different wavelengths is refracted in the prism and the resulting spectra are detected and evaluated.

公开(公告)号：US09651533B2

公开(公告)日：2017-05-16

申请号：US14875709

申请日：2015-10-06

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J5/20 ,  G01N33/15 ,  A61B5/1455 ,  A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  A61B5/145 ,  G01N33/49 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A measurement system includes a wearable measurement device for measuring one or more physiological parameters, including a light source comprising a plurality of light emitting diodes (LEDs) configured to generate an output optical beam with a near-infrared wavelength between 700 nanometers and 2500 nanometers. The light source is configured to increase signal-to-noise ratio by increasing a light intensity and pulse rate of the LEDs. The system includes a plurality of lenses configured to receive the output optical beam and to deliver an analysis output beam to a sample. The wearable measurement device includes a receiver configured to process the analysis output beam reflected or transmitted from the sample and to generate an output signal that may be transmitted to a remote device configured to process the received output status to generate processed data and to store the processed data.

公开(公告)号：US09599510B2

公开(公告)日：2017-03-21

申请号：US14488684

申请日：2014-09-17

Applicant: Cymer, LLC ,  ASML Netherlands B.V.

Inventor： Thomas P. Duffey ,  Herman Philip Godfried

IPC: G03B27/32 ,  G03B27/54 ,  G03B27/74 ,  H01S3/10 ,  H01S3/13 ,  G01J3/28 ,  G03F7/20 ,  G01J11/00 ,  G01J9/00 ,  G01J3/14 ,  G01J3/26 ,  G01J3/02

CPC classification number: G01J3/28 ,  G01J3/027 ,  G01J3/14 ,  G01J3/26 ,  G01J9/00 ,  G01J11/00 ,  G01J2003/2853 ,  G03F7/70041 ,  G03F7/70058 ,  G03F7/70575

Abstract: A method is described for estimating a spectral feature of a pulsed light beam produced by an optical source and directed toward a wafer of a lithography apparatus. The method includes receiving a set of N optical spectra of pulses of the light beam; saving the received N optical spectra to a saved set; transforming the optical spectra in the saved set to form a set of transformed optical spectra; averaging the transformed optical spectra to form an averaged spectrum; and estimating a spectral feature of the pulsed light beam based on the averaged spectrum.

公开(公告)号：US09200961B2

公开(公告)日：2015-12-01

申请号：US14067244

申请日：2013-10-30

Applicant: University of South Carolina

Inventor： Stanley Michael Angel ,  Jerry Chance Carter

IPC: G01J3/45 ,  G01J3/44 ,  G01J3/14 ,  G01J3/453 ,  G01N21/65

CPC classification number: G01J3/44 ,  G01J3/14 ,  G01J3/4531 ,  G01J2003/451 ,  G01N21/65

Abstract: The present subject matter is directed to a device for spectroscopy. The device includes an excitation source and a first spatial heterodyne spectrometer configured to receive wavelengths from the excitation source and filter the wavelengths to produce fringes on a sample. The device also includes a second heterodyne spectrometer configured to receive Raman wavelengths from the sample.

Abstract translation: 本发明涉及用于光谱学的装置。 该装置包括激发源和第一空间外差光谱仪，其被配置为接收来自激发源的波长并过滤波长以在样品上产生条纹。 该装置还包括配置成从样品接收拉曼波长的第二外差光谱仪。

公开(公告)号：US08922776B2

公开(公告)日：2014-12-30

申请号：US13988784

申请日：2011-11-22

Applicant: Reiner Rygiel

Inventor： Reiner Rygiel

IPC: G01N21/00 ,  G01J3/02 ,  G01J3/14 ,  G01J3/36 ,  G02B21/00 ,  G02B27/14

CPC classification number: G01J3/0205 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/14 ,  G01J3/36 ,  G02B21/0076 ,  G02B21/008 ,  G02B27/141

Abstract: A confocal laser scanning microscope for examining a sample has a light source, which generates an illumination light beam, and a scanning unit which deflects the illumination light beam such that it optically scans the sample. A main beam splitter separates the illumination light beam from detection light emerging from the sample. The detection light separated from the illumination light beam passes at least partially through a detection pinhole diaphragm. At least two detector units detect the detection light passing through the detection pinhole diaphragm. An optical element is arranged in the beam direction between the detection pinhole diaphragm and the detector units and splits the detection light into at least two beam bundles and spectrally decomposes it within the beam bundles.

Abstract translation: 用于检查样品的共聚焦激光扫描显微镜具有产生照明光束的光源和使照明光束偏转以使其光学扫描样品的扫描单元。 主分束器将照明光束与从样品出射的检测光分离。 与照明光束分离的检测光至少部分地通过检测针孔膜片。 至少两个检测器单元检测通过检测针孔隔膜的检测光。 在检测针孔光阑和检测器单元之间沿光束方向布置光学元件，并将检测光分裂成至少两束光束束，并在束束内对其进行光谱分解。

公开(公告)号：US08873048B2

公开(公告)日：2014-10-28

申请号：US13518797

申请日：2010-12-13

Applicant: Stefan Florek ,  Michael Okruss ,  Helmut Becker-Ross

Inventor： Stefan Florek ,  Michael Okruss ,  Helmut Becker-Ross

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/18 ,  G01J3/14

CPC classification number: G01J3/1809 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0235 ,  G01J3/14 ,  G01J3/2803 ,  G01J2003/1828

Abstract: A spectrometer assembly (10), comprising an Echelle grating (18; 46) for dispersing radiation entering the spectrometer assembly (10) in a main dispersion direction, and a dispersion assembly (16; 40) for dispersing a parallel radiation bundle generated from the radiation entering the spectrometer assembly in a lateral dispersion direction, is characterized in that the dispersion assembly (16; 40) is reflective, and the dispersion assembly (16; 40) is arranged relative to the Echelle grating (18; 46) in such a way that the parallel radiation bundle is reflected in the direction of the Echelle grating. The Echelle grating (18; 46) may be arranged in such a way that the dispersed radiation is reflected back to the dispersion assembly (16; 40).

Abstract translation: 一种光谱仪组件（10），包括用于分散在主分散方向上进入光谱仪组件（10）的辐射的梯形光栅（18; 46）和用于分散从所述分散体组件（10; 40）产生的平行辐射束 辐射进入光谱仪组件的横向分散方向，其特征在于分散体组件（16; 40）是反射性的，分散体组件（16; 40）相对于Echelle光栅（18; 46） 平行辐射束在Echelle光栅的方向上反射的方式。 可以将梯形光栅（18; 46）布置成使得分散的辐射被反射回到分散体组件（16; 40）。

公开(公告)号：US07319520B2

公开(公告)日：2008-01-15

申请号：US10924422

申请日：2004-08-24

Applicant: Frank Olschewski

Inventor： Frank Olschewski

IPC: G06F7/16 ,  G01J3/30 ,  G01J3/433 ,  G01J3/14 ,  G01J3/18

CPC classification number: G01N21/6458 ,  G01J3/4406 ,  G01J2003/2833 ,  G01N21/6428 ,  G01N2021/6417 ,  G01N2021/6423 ,  G02B21/0064 ,  G02B21/0076

Abstract: A system and a method for setting a fluorescence spectrum measurement system for microscopy is disclosed. Using illuminating light (3) from at least one laser that emits light of one wavelength, a continuous wavelength region is generated. Dyes are stored, with the pertinent excitation and emission spectra, in a database of a computer system (23). For each dye present in the specimen (15), a band of the illuminating light (3) and a band of the detected light (17) are calculated, the excitation and emission spectra read out from the database being employed. Setting of the calculated band in the illuminating light and in the detected light is performed on the basis of the calculation. Lastly, data acquisition is accomplished with the spectral microscope (100).

Abstract translation: 公开了一种用于设置用于显微镜的荧光光谱测量系统的系统和方法。 使用来自发射一个波长的光的至少一个激光器的照明光（3），产生连续的波长区域。 将染料与相关的激发和发射光谱一起存储在计算机系统（23）的数据库中。 对于样品（15）中存在的每种染料，计算照明光（3）的带和检测光（17）的带，从采用数据库读出的激发和发射光谱。 在计算的基础上进行照明光和检测光中的计算频带的设定。 最后，用光谱显微镜（100）完成数据采集。