公开(公告)号：US11692873B2

公开(公告)日：2023-07-04

申请号：US17400233

申请日：2021-08-12

Applicant: PerkinElmer Health Sciences, Inc.

Inventor： Mahsa Farsad ,  David Aikens

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/18 ,  G02B23/02 ,  G01J3/12

CPC classification number: G01J3/0256 ,  G01J3/0208 ,  G01J3/1809 ,  G02B23/02 ,  G01J2003/1208

Abstract: A spectrometer with a Schmidt reflector is described. The spectrometer may include a Schmidt corrector and a dispersive element as separate components. Alternatively, the Schmidt corrector and dispersive element may be combined into a single optical component. The spectrometer may further include a field-flattener lens.

公开(公告)号：US20190017871A1

公开(公告)日：2019-01-17

申请号：US16031409

申请日：2018-07-10

Applicant: NANOLAMBDA KOREA

Inventor： Byung IL Choi

IPC: G01J3/02 ,  G01J3/28 ,  G01J3/18

CPC classification number: G01J3/0254 ,  G01J3/0213 ,  G01J3/0218 ,  G01J3/0297 ,  G01J3/14 ,  G01J3/18 ,  G01J3/28 ,  G01J3/2803 ,  G01J3/2823 ,  G01J2003/1208 ,  G01J2003/2806

Abstract: Spectrum sensors can be continuously calibrated in a manufacturing environment employing a continuously moving platform that carries the spectrum sensors in combination with spatially separated light spectra illuminating a region of the platform. A plurality of spectrum sensors, each including multiple sensor pixels, can be placed on the platform. The spatially separated light spectra can be illuminated over an area of the platform. The plurality of spectrum sensors can be moved with the platform through a region of the spatially separated light spectrum. Each sensor pixel for each of the plurality of spectrum sensors can be calibrated based on response of each spectral channel during passage through the spatially separated light spectra. The entire spectra from a light source can be employed simultaneously to calibrate multiple spectrum sensors in the manufacturing environment.

公开(公告)号：US20180296097A1

公开(公告)日：2018-10-18

申请号：US16015737

申请日：2018-06-22

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/28 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/39 ,  G06F19/00 ,  G01N21/88 ,  G16H40/67 ,  G01J3/02 ,  G01J3/10 ,  G01J3/14 ,  G01N33/02 ,  G01N21/359 ,  G01N21/3563 ,  G01N21/35 ,  G01N33/49 ,  G01N33/44 ,  G01N33/15 ,  G01J3/453 ,  G01J3/42 ,  G01J3/18 ,  G01J3/12 ,  G01M3/38 ,  G01N21/85 ,  G01N21/95 ,  H01S3/00 ,  H01S3/30 ,  H01S3/067

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302 ,  Y02A90/26

Abstract: A measurement system includes a light source having semiconductor sources, a multiplexer, and one or more fused silica fibers configured to form an output optical beam having one or more optical wavelengths modulated at a modulation frequency. A light beam set-up includes a monochromator forming a filtered optical beam. A measurement apparatus delivers the filtered optical beam to a sample. A receiver receives a spectroscopy output beam generated from the sample by the filtered optical beam. The receiver is configured to use a lock-in technique that detects the modulation frequency, and to generate first and second signals responsive to light received while the light source is off and on, respectively. The measurement system improves a signal-to-noise ratio of the spectroscopy output beam by differencing the first and second signals. The receiver processes the spectroscopy output beam using chemometrics or multivariate analysis to permit identification of materials within the sample.

公开(公告)号：US20180120086A1

公开(公告)日：2018-05-03

申请号：US15341104

申请日：2016-11-02

Applicant: Matthias Lenzner

Inventor： Matthias Lenzner

IPC: G01B9/02 ,  G01N21/33 ,  G01N21/35 ,  G01N21/31 ,  G01N33/00

CPC classification number: G01N33/0004 ,  G01J3/00 ,  G01J3/1804 ,  G01J3/45 ,  G01J3/4532 ,  G01J3/4537 ,  G01J2003/1208 ,  G01N2033/0093

Abstract: A technique and device to determine the spectrum of electromagnetic radiation in a certain range of wavelengths comprising: splitting said radiation into more than one beam; let these beams counter-propagate in a Sagnac-type ring interferometer; and imprinting a wavelength-dependent angular tilt onto the wavefront of each beam by at least one dispersive element which preferably is a transmission grating or grism; and re-combining the multiple beams on a detector that exhibits spatial resolution and can therefore resolve the fringes formed by interference; and perform the mathematical operations to determine the spectrum of said radiation from the obtained interferogram, wherein the dispersive element is mounted on a stage providing linear and/or rotational movement.

公开(公告)号：US09861286B1

公开(公告)日：2018-01-09

申请号：US15686198

申请日：2017-08-25

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  A61B5/00 ,  G01N33/49 ,  G01N33/44 ,  G01N33/15 ,  G01N33/02 ,  G01N21/88 ,  G01N21/3563 ,  G01N21/359 ,  G01J3/453 ,  A61B5/145 ,  A61B5/1455 ,  H01S3/30 ,  G01N21/39 ,  G01M3/38 ,  G01J3/28 ,  G01J3/10 ,  G01J3/18 ,  G01J3/14

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device for use with a smart phone or tablet includes LEDs for measuring physiological parameters by modulating the LEDs and generating a near-infrared multi-wavelength optical beam. At least one LED emits at a first wavelength having a first penetration depth and at least another LED emits at a second wavelength having a second penetration depth into tissue. The device includes lenses that deliver the optical beam to the tissue, which reflects the first and second wavelengths. A receiver is configured to capture light while the LEDs are off and while at least one of the LEDs is on and to difference corresponding signals to improve a signal-to-noise ratio of the optical beam reflected from the tissue. The signal-to-noise ratio is further increased by increasing light intensity of at least one of the LEDs. The device generates an output signal representing a non-invasive measurement on blood within the tissue.

公开(公告)号：US09677932B2

公开(公告)日：2017-06-13

申请号：US15335315

申请日：2016-10-26

Applicant: Burt J. Beardsley

Inventor： Burt J. Beardsley

IPC: G01J3/28 ,  G01J3/02 ,  G02B17/08 ,  G02B5/00 ,  G02B27/30 ,  G02B5/04 ,  G02B5/18 ,  G01J3/18 ,  G01N21/25 ,  G01N21/71 ,  G01J3/12

CPC classification number: G01J3/021 ,  G01J3/0208 ,  G01J3/1809 ,  G01J2003/1208 ,  G01N21/718 ,  G02B5/005 ,  G02B5/04 ,  G02B5/1842 ,  G02B17/0848 ,  G02B27/30

Abstract: A spectrograph that includes a first mirror having flat a mirror reflective surface and positioned to reflect light traversing a prism, a second mirror having a concave-shaped reflective mirror surface and positioned to reflect light received from the first mirror, a third mirror having a convex-shaped reflective mirror surface and positioned to receive light reflected by the second mirror, a fourth mirror having a spheroidal reflective mirror surface and positioned to receive light reflected by the third mirror, and a field lens comprising a concave mirror surface in combination with a convex mirror surface, wherein light received by said field lens from said fourth mirror enters said convex mirror surface, traverses said field lens, and exits from said concave mirror surface. The fifth mirror is positioned such that the second mirror, third mirror, fourth mirror, and fifth mirror share a common vertex axis.

公开(公告)号：US09651533B2

公开(公告)日：2017-05-16

申请号：US14875709

申请日：2015-10-06

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J5/20 ,  G01N33/15 ,  A61B5/1455 ,  A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  A61B5/145 ,  G01N33/49 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A measurement system includes a wearable measurement device for measuring one or more physiological parameters, including a light source comprising a plurality of light emitting diodes (LEDs) configured to generate an output optical beam with a near-infrared wavelength between 700 nanometers and 2500 nanometers. The light source is configured to increase signal-to-noise ratio by increasing a light intensity and pulse rate of the LEDs. The system includes a plurality of lenses configured to receive the output optical beam and to deliver an analysis output beam to a sample. The wearable measurement device includes a receiver configured to process the analysis output beam reflected or transmitted from the sample and to generate an output signal that may be transmitted to a remote device configured to process the received output status to generate processed data and to store the processed data.

公开(公告)号：US20150241280A1

公开(公告)日：2015-08-27

申请号：US14631376

申请日：2015-02-25

Applicant: Matthias Lenzner

Inventor： Matthias Lenzner

IPC: G01J3/45 ,  G01J3/02 ,  G01J3/18

CPC classification number: G01J3/0208 ,  G01J3/1804 ,  G01J3/4531 ,  G01J2003/1208

Abstract: A technique and device to determine the spectrum of electromagnetic radiation in a certain range of wavelengths comprising: splitting said radiation into more than one beam; and imprinting a wavelength-dependent angular tilt onto the wavefront of each beam by two dispersive elements; and re-combining the multiple beams on a detector that exhibits spatial resolution and can therefore resolve the fringes formed by interference; and perform the mathematical operations to determine the spectrum of said radiation from the obtained interferogram, wherein the dispersive elements of one beam are mounted on a common stage providing linear and/or rotational movement

Abstract translation: 一种用于确定特定波长范围内的电磁辐射频谱的技术和装置，包括：将所述辐射分成多于一个光束; 并且通过两个色散元件将波长相关的角度倾斜压印在每个光束的波前上; 并且在显示空间分辨率的检测器上重新组合多个光束，并且因此可以解决由干涉形成的条纹; 并且执行数学运算以从所获得的干涉图中确定所述辐射的光谱，其中一个光束的色散元件安装在公共平台上，提供线性和/或旋转运动

公开(公告)号：US20140183362A1

公开(公告)日：2014-07-03

申请号：US14108986

申请日：2013-12-17

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01N21/35

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A system and method for using near-infrared or short-wave infrared (SWIR) light sources for identification of counterfeit drugs may perform spectroscopy using a super-continuum laser to provide detection in a non-contact and non-destructive manner at stand-off or remote distances with minimal sample preparation. Also, near-infrared or SWIR light may penetrate through plastic containers and packaging, permitting on-line inspection and rapid scanning. The near-infrared or SWIR spectroscopy may also be used to detect illicit drugs and their chemical composition. Moreover, the spectroscopic techniques may also be applied to quality assessment and control in pharmaceutical manufacturing, thus permitting the implementation of smart manufacturing with feedback control. Fiber super-continuum lasers may emit light in the near-infrared or SWIR between approximately 1.4-1.8 microns, 2-2.5 microns, 1.4-2.4 microns, 1-1.8 microns. In particular embodiments, the detection system may be a dispersive spectrometer, a Fourier transform infrared spectrometer, or a hyper-spectral imaging detector or camera.

Abstract translation: 使用近红外或短波红外（SWIR）光源识别假冒药物的系统和方法可以使用超连续激光器进行光谱，以在非接触和非破坏性方式提供检测 或距离最小的样品制备。 此外，近红外或SWIR光可以穿透塑料容器和包装，允许在线检查和快速扫描。 近红外或SWIR光谱也可用于检测非法药物及其化学成分。 此外，光谱技术还可以应用于药物制造中的质量评估和控制，从而允许通过反馈控制实现智能制造。 光纤超连续激光器可以在大约1.4-1.8微米，2-2.5微米，1.4-2.4微米，1-1.8微米之间的近红外或者SWIR发光。 在具体实施例中，检测系统可以是色散光谱仪，傅里叶变换红外光谱仪或超光谱成像检测器或照相机。

公开(公告)号：US07663750B2

公开(公告)日：2010-02-16

申请号：US11480287

申请日：2006-06-30

Applicant: Dar Bahatt ,  Chirag Patel ,  Roy H. Tan ,  Derek Prothro

Inventor： Dar Bahatt ,  Chirag Patel ,  Roy H. Tan ,  Derek Prothro

IPC: G01J3/28

CPC classification number: G01N21/31 ,  G01J3/10 ,  G01J3/12 ,  G01J3/18 ,  G01J3/189 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/4406 ,  G01J2003/1204 ,  G01J2003/1208 ,  G01J2003/1213 ,  G01J2003/1226 ,  G01N21/0332 ,  G01N21/253 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/76 ,  G01N2021/6421 ,  G01N2021/6432 ,  G01N2201/06113 ,  G01N2201/0621 ,  G01N2201/0697

Abstract: Systems, including methods, apparatus, and algorithms, for spectrally imaging a two-dimensional array of samples.

Abstract translation: 用于对二维样本阵列进行光谱成像的系统，包括方法，装置和算法。