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    Two-dimensional spectral imaging system
    3.
    发明授权
    Two-dimensional spectral imaging system 有权
    二维光谱成像系统

    公开(公告)号：US07817273B2

    公开(公告)日：2010-10-19

    申请号：US11479962

    申请日：2006-06-30

    申请人： Dar Bahatt ,  Chirag Patel ,  Derek K. Prothro ,  Roy H. Tan

    发明人： Dar Bahatt ,  Chirag Patel ,  Derek K. Prothro ,  Roy H. Tan

    IPC分类号： G01J3/28

    CPC分类号： G01N21/253 ,  G01N21/0332 ,  G01N21/276 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N21/763 ,  G01N2021/0325 ,  G01N2021/6417 ,  G01N2021/6432

    摘要： Systems, including methods, apparatus, and algorithms, for spectrally imaging a two-dimensional array of samples are disclosed. In one such system, a method of sample analysis includes directing light from a two-dimensional array of examination sites onto a detection area such that dispersed light of known spectral composition from each site falls on the detection area. The method further includes assigning a corresponding two-dimensional array of regions of the detection area for detecting spectra from the examination sites based, at least in part, on the known spectral composition. The method also includes placing samples into the two dimensional array of examination sites and obtaining spectral data for each sample based on the detection area.

    摘要翻译： 公开了用于对二维样本阵列进行光谱成像的系统，包括方法，装置和算法。 在一个这样的系统中，样本分析的方法包括将来自检查点的二维阵列的光引导到检测区域，使得来自每个位置的已知光谱组成的分散光落在检测区域上。 该方法还包括至少部分地基于已知的光谱组成，分配用于检测来自检查位点的光谱的检测区域的对应的二维阵列。 该方法还包括将样本置于检查点的二维阵列中，并基于检测区域获得每个样本的光谱数据。

    Devices and Methods for Positioning Dried Reagent In Microfluidic Devices
    4.
    发明申请
    Devices and Methods for Positioning Dried Reagent In Microfluidic Devices 审中-公开
    微流控装置中干燥试剂定位的装置和方法

    公开(公告)号：US20070280857A1

    公开(公告)日：2007-12-06

    申请号：US11422058

    申请日：2006-06-02

    申请人： Maengseok Song ,  Joon Mo Yang ,  Julie C. Lee ,  Nigel P. Beard ,  Yuh-Min Chiang ,  Roy H. Tan ,  Carol Schembri

    发明人： Maengseok Song ,  Joon Mo Yang ,  Julie C. Lee ,  Nigel P. Beard ,  Yuh-Min Chiang ,  Roy H. Tan ,  Carol Schembri

    IPC分类号： B01L3/02

    CPC分类号： B01L3/502723 ,  B01L3/502746 ,  B01L3/502784 ,  B01L2200/0642 ,  B01L2200/0673 ,  B01L2200/0684 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0487 ,  B01L2400/086 ,  C12Q1/6806 ,  Y10T436/2575

    摘要： A microfluidic device may include a sample distribution network including a plurality of sample chambers configured to be loaded with biological sample for biological testing of the biological sample while in the sample chambers, the biological sample having a meniscus that moves within the sample chambers during loading. The sample distribution network may further include a plurality of inlet channels, each inlet channel being in flow communication with and configured to flow biological sample to a respective sample chamber, and a plurality of outlet channels, each outlet channel being in flow communication and configured to flow biological sample from a respective sample chamber. At least some of the sample chambers may include a physical modification configured to control the movement of the meniscus so as to control bubble formation within the at least some sample chambers. At least some of the sample chambers may include a dried reagent positioned within the at least some sample chambers proximate the inlet channels in flow communication with the at least some sample chambers.

    摘要翻译： 微流体装置可以包括样品分配网络，其包括多个样品室，其被配置为装载用于生物样品的生物样品的生物样品，而在样品室中，生物样品具有在加载期间在样品室内移动的弯液面。 样品分配网络还可以包括多个入口通道，每个入口通道与生物样品流动连通并配置成将生物样品流动到相应的样品室，以及多个出口通道，每个出口通道流动连通并且被配置为 从相应的样品室流动生物样品。 至少一些样品室可以包括物理修改，其被配置为控制弯液面的运动，以便控制至少一些样品室内的气泡形成。 至少一些样品室可以包括位于与至少一些样品室流动连通的入口通道附近的至少一些样品室内的干燥试剂。