公开(公告)号：US20240337651A1

公开(公告)日：2024-10-10

申请号：US18631994

申请日：2024-04-10

Applicant: Ricovr Healthcare Inc. ,  Indian Institute of Technology Madras (IIT Madras)

Inventor： Venkata Raghavendra Sai Vemulakonda ,  Divagar Murugan ,  Himanshu Bhatia ,  Joseph Walter Seimetz ,  Elana Michelle Edery

IPC: G01N33/543 ,  G01N21/75 ,  G01N33/68

CPC classification number: G01N33/54346 ,  G01N21/75 ,  G01N33/68 ,  G01N2021/755 ,  G01N2021/757 ,  G01N2333/765 ,  G01N2333/77

Abstract: The disclosure provides methods of detecting a cannabinoid or metabolite thereof in a sample and test kits for the same. For example, the cannabinoid such as tetrahydrocannabinol (THC) bound to bovine serum albumin (BSA) may induce changes in optical properties of an optical biosensor employed for the said detection wherein the optical biosensor is immobilized with a suitable bioreceptor or through interactions with a bioreceptor-nanoparticle conjugate.

公开(公告)号：US20240287902A1

公开(公告)日：2024-08-29

申请号：US18239894

申请日：2023-08-30

Applicant: Halliburton Energy Services, Inc.

Inventor： Christopher Michael Jones ,  Colin Douglas Tisdale

IPC: E21B49/08 ,  G01N21/75 ,  G01N21/84

CPC classification number: E21B49/088 ,  E21B49/0875 ,  G01N21/75 ,  G01N21/84 ,  G01N2021/757 ,  G01N2021/7793 ,  G01N2021/8405

Abstract: A downhole fluid sampling tool may include an optical measurement tool and a viewing region disposed in the optical measurement tool. In examples, a bridge may be disposed in a transparent portion of the flow path between a light source and a light modifier and an optical detector. The bridge includes a structure comprising a substrate and a contrast agent, wherein the contrast agent is any molecule configured to interact with an analyte and alter a property of the analyte and/or contrast agent, wherein the property is detectable by the optical measurement tool.

公开(公告)号：US11703506B2

公开(公告)日：2023-07-18

申请号：US17000322

申请日：2020-08-23

Applicant: ACCELLIX LTD.

Inventor： Harvey Lee Kasdan ,  Julien Meissonnier ,  Yoav Zuta ,  Micha Rosen ,  Yael Himmel ,  Yehoshua Broder ,  Bruce Davis ,  Bruce Goldman ,  Boaz Giron ,  Zion Botesazan ,  Eliezer Blasberg ,  Ilan Semmel ,  Jacques Aschkenasy

IPC: B01L3/00 ,  G01N33/569 ,  G01N21/75 ,  G01N21/64 ,  G01N21/03 ,  G01N15/14 ,  G01N33/50 ,  G01N33/53 ,  G01N33/543 ,  G01N33/58 ,  G01N33/68 ,  G01N15/10 ,  G01N35/00

CPC classification number: G01N33/56972 ,  B01L3/502 ,  B01L3/5027 ,  B01L3/50273 ,  B01L3/502715 ,  B01L3/502761 ,  G01N15/1459 ,  G01N15/1484 ,  G01N21/03 ,  G01N21/6428 ,  G01N21/75 ,  G01N33/5091 ,  G01N33/5302 ,  G01N33/54386 ,  G01N33/569 ,  G01N33/582 ,  G01N33/68 ,  G01N33/6872 ,  B01L2200/025 ,  B01L2200/10 ,  B01L2300/041 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/0877 ,  B01L2300/0883 ,  B01L2300/123 ,  B01L2300/18 ,  B01L2400/0406 ,  B01L2400/0481 ,  B01L2400/0487 ,  G01N2015/1006 ,  G01N2021/0328 ,  G01N2021/6439 ,  G01N2021/6482 ,  G01N2035/00158 ,  G01N2333/70535 ,  G01N2333/70596 ,  G01N2800/26

Abstract: The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.

公开(公告)号：US20230175060A1

公开(公告)日：2023-06-08

申请号：US17939760

申请日：2022-09-07

Applicant: Pacific Biosciences of California, Inc.

Inventor： Adrian FEHR ,  Nathaniel Joseph MCCAFFREY ,  Stephen TURNER

IPC: C12Q1/6874 ,  B01L3/00 ,  G01N21/64 ,  B82Y20/00 ,  G01N33/543 ,  G02B6/122 ,  G01N21/03 ,  G01N21/05 ,  G01N21/75 ,  G01N21/77 ,  C12Q1/6825 ,  C12Q1/6869

CPC classification number: C12Q1/6874 ,  B01L3/502707 ,  G01N21/6452 ,  G01N21/648 ,  B82Y20/00 ,  G01N21/6456 ,  G01N21/6454 ,  G01N33/54373 ,  G02B6/1226 ,  G01N21/0303 ,  G01N21/05 ,  G01N21/75 ,  G01N21/64 ,  G01N21/77 ,  B01L3/502715 ,  C12Q1/6825 ,  G01N21/6428 ,  G01N21/03 ,  C12Q1/6869 ,  G01N21/645 ,  Y10T436/143333 ,  B01L2300/0654 ,  B01L2300/168 ,  G01N2021/0346 ,  G01N2021/757 ,  B01L2300/0663 ,  B01L2300/0816 ,  G01N2021/6434 ,  G01N2021/6441 ,  G01N2201/067 ,  G01N2021/6439 ,  G01N2021/6463 ,  G01N2201/08 ,  G01N2021/7786 ,  G01N2201/068

Abstract: Optics collection and detection systems are provided for measuring optical signals from an array of optical sources over time. Methods of using the optics collection and detection systems are also described.

公开(公告)号：US20190154567A1

公开(公告)日：2019-05-23

申请号：US16313719

申请日：2018-02-09

Applicant: Aquila Biolabs GmBH

Inventor： Konrad Herzog ,  David Frank

IPC: G01N21/25 ,  G01N21/51 ,  B01J19/28

CPC classification number: G01N21/253 ,  B01J19/28 ,  C12M41/06 ,  C12M41/42 ,  G01N15/0205 ,  G01N21/51 ,  G01N21/75 ,  G01N21/85 ,  G01N2015/0053 ,  G01N2021/0325 ,  G01N2021/8405 ,  G01N2035/00524

Abstract: A method for tuning optical measurements on continuously mixed reactors, wherein a content of the reactor has at least one optically detectable measured variable, which is carried out by at least one optical measuring arrangement, wherein at least one optical measurement is tuned to a form, distribution, or movement state of at least one phase of the reactor content, wherein mixing the reactor content causes local changes in the permittivity within the reactor, which is detected at at least one location having a known distance from the at least one optical measuring arrangement to be tuned based on a permittivity signal, and wherein the detected permittivity signal of at least one location having a known distance from the at least one optical measuring arrangement to be tuned is used to tune at least one optical measurement to the form, distribution, or movement state of the reactor content.

公开(公告)号：US20180328149A1

公开(公告)日：2018-11-15

申请号：US15779791

申请日：2016-01-20

Applicant: HALLIBURTON ENERGY SERVICES, INC.

Inventor： Shao Hwa LEE ,  Mine KAZANCI

IPC: E21B41/00

CPC classification number: E21B41/00 ,  B01J8/001 ,  B01J8/006 ,  B01J8/222 ,  B01J8/228 ,  B01J19/0006 ,  B01J19/18 ,  B01J19/1881 ,  B01J2208/00061 ,  B01J2208/00212 ,  B01J2208/00362 ,  B01J2208/00539 ,  B01J2208/00548 ,  B01J2208/00575 ,  B01J2208/00628 ,  B01J2208/00637 ,  B01J2208/00725 ,  B01J2208/00973 ,  B01J2219/0004 ,  B01J2219/00063 ,  B01J2219/00069 ,  B01J2219/00072 ,  B01J2219/00094 ,  B01J2219/00123 ,  B01J2219/00164 ,  B01J2219/00168 ,  B01J2219/00186 ,  B01J2219/002 ,  B01J2219/00216 ,  B01J2219/00218 ,  B01J2219/00225 ,  B01J2219/00231 ,  B01J2219/00236 ,  B01J2219/00238 ,  B01J2219/0024 ,  B01J2219/00243 ,  B01J2219/00272 ,  G01N11/08 ,  G01N21/19 ,  G01N21/21 ,  G01N21/23 ,  G01N21/272 ,  G01N21/33 ,  G01N21/35 ,  G01N21/47 ,  G01N21/64 ,  G01N21/65 ,  G01N21/75 ,  G01N21/84 ,  G01N2021/8416 ,  G01N2201/12

Abstract: An actuator is provided that includes a housing, a linear actuating shaft disposed within the housing, a piston coupled with the shaft, and a fluid barrier disposed on an end of the shaft and encircled by the piston. The piston is movable longitudinally between an extended configuration and a retracted configuration upon rotation of the shaft. The fluid barrier engages an inner surface of the piston preventing fluid communication across the fluid barrier. The fluid barrier has a shaft engaging side which receives the shaft and a fluid facing side. A cavity is formed between the piston and the fluid facing side and expands when the piston moves to the extended configuration and contracts when the piston moves to the retracted configuration. A port is disposed in the piston and extends from the cavity to external the piston thereby permitting fluid communication between the cavity and external the piston.

公开(公告)号：US20180252639A1

公开(公告)日：2018-09-06

申请号：US15910621

申请日：2018-03-02

Applicant: MAX Analytical Technologies, Inc.

Inventor： Martin L. Spartz ,  Peter Paul Behnke ,  Charles Mark Phillips ,  Adam R. Klempner ,  Anthony S. Bonanno

IPC: G01N21/3504 ,  G01N21/64 ,  G01N21/75 ,  G01N21/94

CPC classification number: G01N21/3504 ,  G01N21/031 ,  G01N21/0317 ,  G01N21/05 ,  G01N21/643 ,  G01N21/75 ,  G01N21/94 ,  G01N33/0013 ,  G01N33/0042 ,  G01N2021/1734 ,  G01N2021/174 ,  G01N2021/354 ,  G01N2021/3595 ,  G01N2021/8411

Abstract: A system and method for determining impurities in a beverage grade gas such as CO2 or N2 relies on a coupling of FTIR analysis and UV fluorescence detection. Conversion of reduced sulphur present in some impurities to SO2 can be conducted using a furnace. In some cases, CO2 % also is determined.

公开(公告)号：US10054520B2

公开(公告)日：2018-08-21

申请号：US14743170

申请日：2015-06-18

Applicant: STAT-DIAGNOSTICA & INNOVATION, S.L.

Inventor： Jordi Carrera Fabra ,  Rafael Bru Gibert ,  Anna Comengés Casas

IPC: C12Q1/68 ,  C12P19/34 ,  B01L3/00 ,  G01N1/10 ,  G01N21/75 ,  G01N1/38 ,  G01N1/02 ,  G01N1/40

CPC classification number: G01N1/10 ,  B01L3/502715 ,  B01L3/5029 ,  B01L2200/027 ,  B01L2300/0809 ,  B01L2300/1822 ,  B01L2300/1827 ,  B01L2400/0433 ,  B01L2400/0481 ,  B01L2400/0487 ,  G01N1/38 ,  G01N21/75 ,  G01N2001/028 ,  G01N2001/4061

Abstract: A system and method for eluting a sample from a swab are presented. The system includes a chamber dimensioned to receive at least a portion of the length of at least one swab, a fluidic channel connected to the chamber, and an actuator. The chamber has at least one wall being a flexible film. The fluidic channel is configured to at least one of introduce and expel liquids from the chamber. The actuator is configured to contact an outer surface of the flexible film such that movement of the actuator against the outer surface of the flexible film causes a respective movement of the at least one swab when the at least one swab is disposed next to an inner surface of the flexible film. The respective movement of the at least one swab elutes the sample from the at least one swab into the chamber.

公开(公告)号：US10006866B2

公开(公告)日：2018-06-26

申请号：US14372707

申请日：2013-01-17

Applicant: Hoffmann-La Roche Inc.

Inventor： Christof Fattinger

IPC: C12M1/34 ,  G01N21/75 ,  G01N21/552 ,  G01N21/77 ,  G01N33/543

CPC classification number: G01N21/75 ,  G01N21/552 ,  G01N21/7743 ,  G01N33/54373

Abstract: A device for use in the detection of binding affinities comprises a planar waveguide (2) arranged on a substrate (3), and an optical coupler (4) for coupling coherent light (1) of a predetermined wavelength into the planar waveguide. The coherent light propagates through the planar waveguide (2) with an evanescent field (6) propagating along an outer surface (5) of the planar waveguide. The outer surface (5) of the planar waveguide comprises binding sites (7) thereon capable of binding target samples (8) to the binding sites (7) such that light of the evanescent field (6) is scattered by target samples (8) bound to the binding sites (7). The binding sites (7) are arranged along a plurality of predetermined lines (9) which are arranged such that the scattered light constructively interferes at a predetermined detection location with a difference in optical path length which is an integer multiple of the predetermined wavelength.

公开(公告)号：US20180164220A1

公开(公告)日：2018-06-14

申请号：US15889484

申请日：2018-02-06

Applicant: Samsung Electronics Co., Ltd.

Inventor： Jin-young Park ,  Youn-suk Choi ,  Hye-jung Seo ,  Jae-yeon Jung ,  Young-ki Hahn ,  Hyo-young Jeong ,  Joon-hyung Lee ,  Soo-suk Lee

IPC: G01N21/75 ,  G01N21/78 ,  G01N21/77

CPC classification number: G01N21/75 ,  G01N21/78 ,  G01N2021/7796

Abstract: Provided is a device for measuring electrolyte ions that is capable of providing a uniform pH environment in the region of an optode, and a method of measuring electrolyte ion concentration using the device.