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    CELLULOSE AND/OR HEMICELLULOSES DEGRADING ENZYMES FROM MACROPHOMINA PHASEOLINA AND USES THEREOF
    9.
    发明申请
    CELLULOSE AND/OR HEMICELLULOSES DEGRADING ENZYMES FROM MACROPHOMINA PHASEOLINA AND USES THEREOF 有权
    纤维素和/或致细胞毒素降解大蒜素的酶及其用途

    公开(公告)号：US20150291945A1

    公开(公告)日：2015-10-15

    申请号：US14421774

    申请日：2013-08-15

    申请人： Bangladesh Jute Research Institute

    发明人： Maqsudul Alam ,  Mohammed S. Islam ,  Mohammed M. Hossen ,  Mohammed S. Haque ,  Mohammed M. Alam

    IPC分类号： C12N9/24 ,  C12N9/38 ,  C12N9/88 ,  C12N9/34 ,  C12N9/42 ,  C12N9/26

    CPC分类号： C12N9/2402 ,  C12N9/2408 ,  C12N9/2428 ,  C12N9/2437 ,  C12N9/244 ,  C12N9/2445 ,  C12N9/2471 ,  C12N9/2482 ,  C12N9/2494 ,  C12N9/88 ,  C12Y302/01037 ,  C12Y302/01051 ,  C12Y302/01055 ,  C12Y302/01059 ,  C12Y302/01075 ,  C12Y302/01089 ,  C12Y302/0113 ,  C12Y302/01177

    摘要： The present invention provides nucleotide sequences of Macrophomina phaseolina (“M. phaseolina”) that encodes proteins/enzymes with cellulolytic activity, including a cellulase activity, a endoglucanase, a cellobiohydrolase, a β-glucosidase, a a-glucosidase, a xylanase, a mannanse, a β-xylosidase, a a-xylosidase, a galactosidase, an arabinofuranosidase, a a-fucosidases, a β-galactanase, an unsaturated β-glucuronyl hydrolase and/or oligomerase activity. Vectors, expression constructs and host cells comprising and/or consisting of the nucleotide sequences of the enzyme genes are also provided. The invention further provides methods for producing the enzymes and methods for modifying the enzymes in order to improve their desirable characteristics. The enzymes of the invention can be used in a variety of, but not limited to, pharmaceutical, agricultural, food and feed processing, biofuel, energy efficiency and industrial contexts. These enzymes are also useful for complete hydrolysis of lignocellulosic biomass into simple sugar that can then be fermented to liquid fuels and chemical feedstocks.

    摘要翻译： 本发明提供了编码具有纤维素分解活性的蛋白质/酶的Macrophomina phaseolina（“M. phaseolina”）的核苷酸序列，包括纤维素酶活性，内切葡聚糖酶，纤维二糖水解酶，葡糖苷酶，α-葡糖苷酶，木聚糖酶， 甘露聚糖，α-木糖苷酶，α-木糖苷酶，半乳糖苷酶，阿拉伯呋喃糖苷酶，α-岩藻糖苷酶，β-半乳糖苷酶，不饱和的 - 葡萄糖醛酸水解酶和/或寡聚酶活性。 也提供了包含和/或由该酶基因的核苷酸序列组成的载体，表达构建体和宿主细胞。 本发明还提供了用于生产酶的方法和用于改变酶的方法，以便改善其期望的特性。 本发明的酶可以多种但不限于制药，农业，食品和饲料加工，生物燃料，能源效率和工业环境。 这些酶也可用于将木质纤维素生物质完全水解成单糖，然后将其发酵成液体燃料和化学原料。

    Mutanase
    10.
    发明授权
    Mutanase 失效
    转谷氨酰胺酶

    公开(公告)号：US4353891A

    公开(公告)日：1982-10-12

    申请号：US190621

    申请日：1971-10-19

    申请人： Bernhard Guggenheim ,  Hans-Rudolf Muhlemann

    发明人： Bernhard Guggenheim ,  Hans-Rudolf Muhlemann

    IPC分类号： A61K8/66 ,  A61Q11/00 ,  C12N9/24 ,  A61K7/28

    CPC分类号： C12Y302/01059 ,  A61K8/66 ,  A61Q11/00 ,  C12N9/2428 ,  C12Y302/01084 ,  Y10S435/885

    摘要： This invention relates to a class of .alpha.1,3 glucan 3-glucanohydrolase named mutanase. The .alpha.1,3 glucosidic bonded polysaccharides hydrolyzed by these enzymes, herein termed mutan, forms part of the matrix material of dental plaque.Mutanase may be produced by culturing microorganisms such as, Trichoderma, Penicillium, or Streptococcus on a glucan characterized by at least 50% alpha -1, 3 glucosidic bonds.Mutanase containing compositions are adapted for disintegrating in vivo essential structural components of dental plaque.

    摘要翻译： 本发明涉及一类称为齿斑葡聚糖酶的α1,3葡聚糖3-葡聚糖水解酶。 由这些酶水解的α1,3糖苷键合的多糖，这里称为mutan，形成牙斑基质材料的一部分。 变种酶可以通过以特征在于至少50％的α-1,3-糖苷键的葡聚糖培养微生物如木霉属，青霉属或链球菌来产生。 含有变种酶的组合物适于在体内分解牙菌斑的基本结构组分。