公开(公告)号：US12110347B2

公开(公告)日：2024-10-08

申请号：US17680581

申请日：2022-02-25

申请人： NUTRITION & BIOSCIENCES USA 4, INC.

发明人： Qiong Cheng ,  Robert DiCosimo ,  Arthur Ouwehand ,  Zheng You ,  Mark S. Payne ,  Jian Ping Lai ,  Kristin Ruebling-Jass ,  Steven Cary Rothman

IPC分类号： C08B37/00 ,  A21D13/45 ,  A21D13/80 ,  A23C9/13 ,  A23G3/36 ,  A23G9/32 ,  A23L2/52 ,  A23L7/126 ,  A23L7/135 ,  A23L21/10 ,  A23L29/30 ,  A23L33/21 ,  A61K31/716 ,  C08L5/00 ,  C12N9/10 ,  C12N9/44 ,  C12P19/04 ,  C12P19/08 ,  C12P19/18

CPC分类号： C08B37/0009 ,  A21D13/45 ,  A21D13/80 ,  A23C9/13 ,  A23G3/36 ,  A23G9/32 ,  A23L2/52 ,  A23L7/126 ,  A23L7/135 ,  A23L21/10 ,  A23L29/37 ,  A23L33/21 ,  A61K31/716 ,  C08L5/00 ,  C12N9/1051 ,  C12N9/246 ,  C12P19/04 ,  C12P19/08 ,  C12P19/18 ,  C12Y204/00 ,  C12Y204/01002 ,  C12Y204/01005 ,  C12Y302/01 ,  C12Y302/01068 ,  A23V2002/00 ,  C08L2203/02 ,  C08L2203/12 ,  C08L2205/16 ,  A61K31/716 ,  A61K2300/00

摘要： An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.

公开(公告)号：US20240325337A1

公开(公告)日：2024-10-03

申请号：US18654403

申请日：2024-05-03

申请人： Probioticsmart, LLC

发明人： Daniel J. DuBourdieu ,  Rajiv Lall

IPC分类号： A61K31/315 ,  A23K10/16 ,  A23K20/111 ,  A23K20/20 ,  A23K50/75 ,  A23L33/00 ,  A23L33/105 ,  A23L33/16 ,  A61K31/192 ,  A61K31/198 ,  A61K31/353 ,  A61K31/385 ,  A61K31/7008 ,  A61K31/716 ,  A61K33/04 ,  A61K35/748 ,  A61P3/02 ,  A61P37/06 ,  A61P39/06 ,  C07F3/06

CPC分类号： A61K31/315 ,  A23K10/16 ,  A23K20/111 ,  A23K20/30 ,  A23K50/75 ,  A23L33/105 ,  A23L33/16 ,  A23L33/40 ,  A61K31/192 ,  A61K31/198 ,  A61K31/353 ,  A61K31/385 ,  A61K31/7008 ,  A61K31/716 ,  A61K33/04 ,  A61K35/748 ,  A61P3/02 ,  A61P37/06 ,  A61P39/06 ,  C07F3/06 ,  A23V2002/00

摘要： The invention is directed to tetrahydrocurcuminoid-metal complexes. The complexes can be included in compositions that further include additional nutraceutical antimicrobials, antioxidants, and immune boosters. The tetrahydrocurcuminoid-metal complexes can be administered to animals to increase animal health, reduce stress, reduce oxidative stress, maintain health, improve health, improve immunity, improve vaccination efficacy, increase feed conversion rate, decrease pro-inflammatory cytokine levels, or any combination thereof in an animal. The tetrahydrocurcuminoid-metal complexes of the invention exhibit enhanced bioavailability relative to the individual, non-complexed components.

公开(公告)号：US12036233B2

公开(公告)日：2024-07-16

申请号：US15780214

申请日：2018-03-22

申请人： OPTERION Health AG

发明人： Guido Grentzmann ,  Hjalmar Steinhauer

IPC分类号： A61K31/716 ,  A61K47/26 ,  A61M1/28 ,  A61K9/08

CPC分类号： A61K31/716 ,  A61K47/26 ,  A61M1/287 ,  A61K9/08

摘要： Carbohydrate compositions for dialysis and methods of making and using them are provided.

公开(公告)号：US20240226135A1

公开(公告)日：2024-07-11

申请号：US18289021

申请日：2022-04-20

申请人： Asahi Group Holdings, Ltd.

发明人： Yu SHIMADA ,  Jumpei YOSHIDA ,  Taichi MINAMI ,  Tetsuya ISHIDA ,  Takeshi SHIRAI ,  Yu IMAI

IPC分类号： A61K31/716 ,  A61K31/715 ,  A61K31/736 ,  A61K36/064 ,  A61P37/04 ,  C12P19/04

CPC分类号： A61K31/716 ,  A61K31/715 ,  A61K31/736 ,  A61K36/064 ,  A61P37/04 ,  C12P19/04 ,  A61K2236/13 ,  A61K2236/19 ,  A61K2236/53

摘要： Provided is an immunostimulator that contains β-glucan derived from yeast cell walls and has a high immunostimulating effect. The immunostimulator contains β-glucan derived from yeast cell walls and the β-glucan content is from 25% by mass to 45% by mass.

公开(公告)号：US12029752B2

公开(公告)日：2024-07-09

申请号：US16484002

申请日：2015-07-06

申请人： Koye Pharmaceuticals Private Limited

发明人： Ajay Nilawar

IPC分类号： A61K31/718 ,  A23L29/219 ,  A23L29/238 ,  A23L33/00 ,  A23L33/21 ,  A61K31/716 ,  A61K31/721 ,  A61K31/736 ,  A61K45/06 ,  A61P1/00 ,  A61P1/10 ,  A61P3/00 ,  A61P3/06 ,  A61P3/10

CPC分类号： A61K31/718 ,  A23L29/219 ,  A23L29/238 ,  A23L33/21 ,  A23L33/30 ,  A61K31/716 ,  A61K31/721 ,  A61K31/736 ,  A61K45/06 ,  A61P1/00 ,  A61P1/10 ,  A61P3/00 ,  A61P3/06 ,  A61P3/10

摘要： A water soluble dietary fibre composition and use thereof is disclosed. The composition comprises: (a) partially hydrolysed and re-polymerized starch, and (b) partially hydrolysed Guar gum.

公开(公告)号：US11951122B2

公开(公告)日：2024-04-09

申请号：US17390048

申请日：2021-07-30

申请人： Chao-Cheng Chen

发明人： Chao-Cheng Chen

IPC分类号： A61K31/716 ,  A61K9/00 ,  A61K45/06 ,  A61P1/12 ,  C12P19/04 ,  C12R1/02

CPC分类号： A61K31/716 ,  A61K9/0053 ,  A61K45/06 ,  A61P1/12 ,  C12P19/04 ,  C12R2001/02

摘要： Provided is a use of fibers formed of β-1-4-glucan in manufacturing a composition for preventing or treating diarrhea, constipation or irritable bowel syndrome, wherein the fibers have a diameter between 15 nm to 35 nm and a mean length of between 1.5 μm and 3.5 μm. Also provided is a method for preventing or treating diarrhea, constipation or irritable bowel syndrome with the fibers formed of β-1-4-glucan.

公开(公告)号：US20230365721A1

公开(公告)日：2023-11-16

申请号：US18028627

申请日：2021-09-27

申请人： CASE WESTERN RESERVE UNIVERSITY

发明人： Mei ZHANG

IPC分类号： C08B37/00 ,  A61K31/716 ,  A61K36/899

CPC分类号： C08B37/0024 ,  C08B37/0003 ,  A61K31/716 ,  A61K36/899 ,  A61K2236/37 ,  A61K2236/30

摘要： A composition comprising an oat derived, salt precipitated β-(1,3)-(1,4) glucan having a molecular weight from about 150 kDa to about 250 kDa, a Mw/Mn ratio of about 1.0 to about 1.25, and a D3/D4 ratio of about 1.5 to less than about 2.0.

公开(公告)号：US11815435B2

公开(公告)日：2023-11-14

申请号：US16488911

申请日：2018-02-23

申请人： HiberCell, Inc.

发明人： Nandita Bose ,  Nadine Ottoson ,  Ben Harrison ,  Jamie Lowe ,  Mark Uhlik ,  Jeremy Graff ,  Richard Huhn

IPC分类号： G01N33/68 ,  A61K31/716

CPC分类号： G01N33/6854 ,  A61K31/716 ,  G01N2400/24 ,  G01N2800/52

摘要： This disclosure provides, in one aspect, dosing strategies for soluble β-glucan immunotherapy to optimize acute immunopharmacodynamic responses for the immunotherapy and/or subject. It also provides a method for analyzing a sample from a subject for a biomarker to identify the appropriate dosing strategy for soluble β-glucan immunotherapy. Generally, the method includes obtaining a biological sample from a subject, analyzing the sample for a biomarker anti-β-glucan antibody level or immunopharmacodynamic response level, classifying the subject into a subgroup based on the biomarker anti-β-glucan antibody level or immunopharmacodynamic response level and identifying the appropriate dosing strategy based on the subgroup classification.

公开(公告)号：US11779620B2

公开(公告)日：2023-10-10

申请号：US17221411

申请日：2021-04-02

申请人： TURTLE BEAR HOLDINGS, LLC

发明人： Paul E. Stamets

IPC分类号： A61K36/074 ,  A61K36/07 ,  A61K47/10 ,  A61P31/12 ,  A61K45/06 ,  A61K31/716 ,  A61P37/06 ,  A61K47/02

CPC分类号： A61K36/074 ,  A61K31/716 ,  A61K36/07 ,  A61K45/06 ,  A61K47/02 ,  A61K47/10 ,  A61P31/12 ,  A61P37/06

摘要： Described herein are combined fungal compositions for treating, prophylaxis of, or ameliorating symptoms of one or more adverse reactions triggered by an infectious disease or condition that causes an inflammatory response. In one aspect the composition comprises an aqueous or solid fraction of Trametes versicolor and Fomitopsis officinalis mycelium, fermented substrates thereof, or combinations thereof.

公开(公告)号：US11744847B2

公开(公告)日：2023-09-05

申请号：US17156146

申请日：2021-01-22

申请人： KEMIN INDUSTRIES, INC.

发明人： Geoffrey Paul Horst ,  Robert Bernard Levine

IPC分类号： A61K31/716 ,  A61K45/06 ,  A61K35/68 ,  A61K9/14 ,  A61K33/30 ,  A61K39/39 ,  A23L33/125 ,  A61P37/04 ,  A61P39/00 ,  A61P3/00 ,  A61P3/06 ,  A61P31/04 ,  A61P1/00 ,  A61K39/00

CPC分类号： A61K31/716 ,  A23L33/125 ,  A61K9/14 ,  A61K33/30 ,  A61K35/68 ,  A61K39/39 ,  A61K45/06 ,  A61P1/00 ,  A61P3/00 ,  A61P3/06 ,  A61P31/04 ,  A61P37/04 ,  A61P39/00 ,  A23V2002/00 ,  A61K2039/55583 ,  A61K31/716 ,  A61K2300/00 ,  A61K33/30 ,  A61K2300/00

摘要： The present application relates to beta-1,3-glucan and uses thereof to modulate immunity in the human body. Also provided are methods for treatment and/or prevention of high cholesterol, diabetes, and allergies. Also provided are methods for treatment and/or prevention of intestinal inflammation.