公开(公告)号：US12121537B2

公开(公告)日：2024-10-22

申请号：US17936361

申请日：2022-09-28

申请人： RHA INVESTMENT LIMITED

发明人： Shawn J. Green

IPC分类号： A61K36/00 ,  A23L33/00 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A61K9/00 ,  A61K9/20 ,  A61K31/375 ,  A61K31/51 ,  A61K31/519 ,  A61K31/714 ,  A61K33/00 ,  A61K33/06 ,  A61K36/185 ,  A61K36/21 ,  A61K36/74 ,  A61K47/02 ,  A61K47/12 ,  A61K47/38 ,  A61K47/46

CPC分类号： A61K33/00 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A23L33/30 ,  A61K9/0056 ,  A61K9/0095 ,  A61K9/2054 ,  A61K9/2068 ,  A61K31/375 ,  A61K31/51 ,  A61K31/519 ,  A61K31/714 ,  A61K33/06 ,  A61K36/185 ,  A61K36/21 ,  A61K36/74 ,  A61K47/02 ,  A61K47/12 ,  A61K47/38 ,  A61K47/46 ,  A23V2002/00 ,  A61K36/74 ,  A61K2300/00 ,  A61K36/185 ,  A61K2300/00

摘要： Compositions and methods for improving nitric oxide levels in a subject, comprising administering to a subject, a composition comprising dietary nitrate derived from potassium nitrate, beet root (whole plant, powder, plant extract), and/or nitrate-rich leafy green portions (whole plant, powder, plant extract) that improve functional nitric oxide levels in subjects as shown by increasing salivary bioconversion of nitrate to nitrite, a necessary a required step for nitric oxide mediated health benefits. The disclosed novel compositions improve cardiac health, lowers blood pressure, intraocular pressure, and LDL and restores nitric oxide mediated cardiovascular benefits, including but not limited, restoring endothelium function and improving flow mediated dilation.

公开(公告)号：US12109036B2

公开(公告)日：2024-10-08

申请号：US17675903

申请日：2022-02-18

申请人： Gravitas Medical, Inc.

发明人： Daniel R. Burnett ,  Marcie Hamilton ,  Evan S. Luxon ,  Alexander Vergara ,  Saheel Sutaria

IPC分类号： A61B5/00 ,  A23L33/00 ,  A23L35/00 ,  A61B1/273 ,  A61B5/01 ,  A61B5/03 ,  A61B5/107 ,  A61B5/145 ,  A61J15/00

CPC分类号： A61B5/4238 ,  A23L33/30 ,  A23L35/00 ,  A61B1/2736 ,  A61B5/01 ,  A61B5/036 ,  A61B5/1073 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/4848 ,  A61B5/486 ,  A61B5/6847 ,  A61B5/6852 ,  A61B5/6865 ,  A61B5/6871 ,  A61B5/742 ,  A61J15/008 ,  A61B2562/0204

摘要： Devices and methods to measure gastric residual volume (GRV) are described where at least one additive component (a GRV indicator) may be dispersed in a body lumen such as a stomach. The GRV indicator may changes a physical (chemical, electrical, thermal, mechanical, optical, etc.) characteristic within the stomach by a measureable degree. This degree of change and/or the rate of return to the previous state, may be used to determine the GRV of a patient. The determined GRV can also be used to automatically or semi-automatically control the patient's feeding rate and/or volume and/or frequency to adequately nourish the patient but avoid complications. The physical characteristic(s) may also be used to detect that the feeding catheter or tube is in the correct location (ie stomach vs lung or esophagus.

公开(公告)号：US20240245735A1

公开(公告)日：2024-07-25

申请号：US18364151

申请日：2023-08-02

申请人： DUPONT NUTRITION BIOSCIENCES APS

发明人： Heli Putaala ,  Sofia Forssten ,  Sampo Lahtinen ,  Arthur Ouwehand ,  Jaana Mättö ,  Harri Mäkivuokko ,  Janne Nikkilä

IPC分类号： A61K35/747 ,  A23L33/00 ,  A23L33/135 ,  A61K35/745 ,  A61P1/04 ,  A61P1/12 ,  A61P1/14

CPC分类号： A61K35/747 ,  A23L33/135 ,  A23L33/30 ,  A61K35/745 ,  A61P1/04 ,  A61P1/12 ,  A61P1/14

摘要： The present invention relates to bacteria and metabolites thereof that are capable of binding to A, B and/or O blood type antigens or which are acid and/or bile tolerant, their use in probiotic compositions and food products, and methods for their selection. The invention also relates to the use of said bacteria and metabolites for the prevention and/or treatment of gastrointestinal disorders.

公开(公告)号：US12029752B2

公开(公告)日：2024-07-09

申请号：US16484002

申请日：2015-07-06

申请人： Koye Pharmaceuticals Private Limited

发明人： Ajay Nilawar

IPC分类号： A61K31/718 ,  A23L29/219 ,  A23L29/238 ,  A23L33/00 ,  A23L33/21 ,  A61K31/716 ,  A61K31/721 ,  A61K31/736 ,  A61K45/06 ,  A61P1/00 ,  A61P1/10 ,  A61P3/00 ,  A61P3/06 ,  A61P3/10

CPC分类号： A61K31/718 ,  A23L29/219 ,  A23L29/238 ,  A23L33/21 ,  A23L33/30 ,  A61K31/716 ,  A61K31/721 ,  A61K31/736 ,  A61K45/06 ,  A61P1/00 ,  A61P1/10 ,  A61P3/00 ,  A61P3/06 ,  A61P3/10

摘要： A water soluble dietary fibre composition and use thereof is disclosed. The composition comprises: (a) partially hydrolysed and re-polymerized starch, and (b) partially hydrolysed Guar gum.

公开(公告)号：US20240215627A1

公开(公告)日：2024-07-04

申请号：US18428005

申请日：2024-01-31

申请人： SOCIÉTÉ DES PRODUITS NESTLÉ S.A.

发明人： Denis Breuille ,  Etienne Pouteau ,  Simina Florentina Popa Nita ,  Laurence Donato-Capel

IPC分类号： A23L33/19 ,  A23C9/13 ,  A23K20/147 ,  A23K20/163 ,  A23L33/00 ,  A23L33/21 ,  A61K35/20 ,  A61K38/01

CPC分类号： A23L33/19 ,  A23C9/1307 ,  A23K20/147 ,  A23K20/163 ,  A23L33/21 ,  A23L33/30 ,  A23L33/40 ,  A61K35/20 ,  A61K38/018 ,  A23V2002/00 ,  A23V2200/00

摘要： The present invention relates to the treatment or prevention of conditions linked to reduced muscle mass or reduced muscle protein synthesis rate. A subject matter of the invention is a composition comprising complexes of whey protein micelles and pectin for use in the treatment or prevention of a condition selected from the group consisting of sarcopenia, muscle atrophy and negative nitrogen balance. Further aspects of the invention relate to the non-therapeutic use of a composition comprising complexes of whey protein micelles and pectin and a food composition.

公开(公告)号：US11980215B2

公开(公告)日：2024-05-14

申请号：US17749828

申请日：2022-05-20

申请人： SOCIÉTÉ DES PRODUITS NESTLÉ S.A.

发明人： Carlos Antonio DeCastro ,  Cristina Cruz-Hernandez ,  Frederic Destaillats ,  Francesca Giuffrida ,  Sagar Thakkar ,  Rajat Mukherjee

IPC分类号： A23L33/00 ,  A23L33/115 ,  A23L33/12 ,  A23L33/17

CPC分类号： A23L33/40 ,  A23L33/115 ,  A23L33/12 ,  A23L33/17 ,  A23L33/30 ,  A23V2002/00 ,  A23V2002/00 ,  A23V2200/332 ,  A23V2250/1846 ,  A23V2250/1848 ,  A23V2250/185

摘要： Synthetic nutritional formulations, particularly milk based compositions, for infants and children are especially adapted to the age of the child. They are adapted to fulfill the nutritional needs of the child, ensuring balanced growth and development and thereby reducing the risk of obesity.

公开(公告)号：US20240115630A1

公开(公告)日：2024-04-11

申请号：US18317443

申请日：2023-05-15

申请人： Dupont Nutrition Biosciences Aps

发明人： Lotta Stenman ,  Sampo Lahtinen

IPC分类号： A61K35/745 ,  A23L33/00 ,  A23L33/135 ,  A23L33/26 ,  A61K47/36 ,  A61P3/00 ,  C12N1/20

CPC分类号： A61K35/745 ,  A23L33/135 ,  A23L33/26 ,  A23L33/30 ,  A61K47/36 ,  A61P3/00 ,  C12N1/20 ,  C12N1/205 ,  A23V2002/00 ,  A23V2200/3204 ,  A23V2200/332 ,  C12R2001/01

摘要： This invention relates to the use of a bacterium of the genus Bifidobacterium, particularly, but not exclusively, a bacterium of the Bifidobacterium animalis ssp. lactis strain 420 (B420) for use in reducing food, energy and/or fat intake.

公开(公告)号：US11883445B2

公开(公告)日：2024-01-30

申请号：US16980712

申请日：2019-03-14

申请人： Emory University

发明人： Rheinallt Jones ,  Trevor Michael Darby

IPC分类号： A61K35/744 ,  A61K35/747 ,  A61K39/09 ,  A61K35/00 ,  A61K9/00 ,  A23L33/00

CPC分类号： A61K35/744 ,  A23L33/30 ,  A61K9/0095 ,  A61K39/09 ,  A23V2400/231 ,  A61K35/747 ,  A61K2035/115

摘要： This disclosure relates to methods of using beneficial bacterial such as, a Lactococcus lactis strain, to manage, treat, or prevent obesity, fatty liver disease, harmful ionizing radiation, and other conditions or aliments. In certain embodiments, the subject is at risk or, susceptible to, exhibiting symptoms of, or diagnosed with a disease or conditions disclosed herein. In certain embodiments, methods comprise administering an effective amount of a Lactococcus lactis strain to a subject in need thereof. In certain embodiments, the Lactococcus lactis strain is Lactococcus lactis subsp. cremoris ATCC® 19257 or a mutant thereof.

公开(公告)号：US11826394B2

公开(公告)日：2023-11-28

申请号：US17336816

申请日：2021-06-02

申请人： Kodimule Shyam Prasad

发明人： Kodimule Shyam Prasad

IPC分类号： A61K36/00 ,  A61K36/53 ,  A61K31/19 ,  A61K31/045 ,  A61K9/68 ,  A61P3/04 ,  A61K9/20 ,  A61K9/48 ,  A23L33/00 ,  A23L33/105 ,  A61K9/00

CPC分类号： A61K36/53 ,  A23L33/105 ,  A23L33/30 ,  A61K9/006 ,  A61K9/0058 ,  A61K9/20 ,  A61K9/4808 ,  A61K31/045 ,  A61K31/19 ,  A61P3/04

摘要： A method of modulating body weight using a composition of rosemary extract having a pre-determined amount of ursolic acid.

公开(公告)号：US11806381B2

公开(公告)日：2023-11-07

申请号：US17172650

申请日：2021-02-10

申请人： Naglaa Hussein

发明人： Naglaa Hussein

IPC分类号： A61K36/8962 ,  A23L33/105 ,  A61K9/00 ,  A61P19/02 ,  A23L33/00

CPC分类号： A61K36/8962 ,  A23L33/105 ,  A23L33/30 ,  A61K9/0053 ,  A61P19/02

摘要： Methods for treating knee osteoarthritis in a patient are disclosed. In one embodiment, a method for treating a knee osteoarthritis patient using an oral dried garlic supplement, wherein the treating comprises administering 900 mg of the oral dried garlic supplement on a daily basis. In one embodiment, 1800 mg of the oral dried garlic supplement is used.