公开(公告)号：US20240358650A1

公开(公告)日：2024-10-31

申请号：US18751870

申请日：2024-06-24

申请人： Pinata Holdings Inc.

发明人： Michael OGBURN ,  Christopher PRICE

IPC分类号： A61K9/50 ,  A61K9/48 ,  A61K38/26

CPC分类号： A61K9/5042 ,  A61K9/4808 ,  A61K9/4858 ,  A61K38/26

摘要： Provided herein are pharmaceutical compositions, kits comprising pharmaceutical compositions, methods of treating disease, and methods of making compositions and kits described herein. The pharmaceutical compositions described herein are powdery pharmaceutical compositions. The powdery pharmaceutical compositions may be administered by an inhaler device described herein. The powdery pharmaceutical compositions may be administered by gummies described herein.

公开(公告)号：US12128056B2

公开(公告)日：2024-10-29

申请号：US17365949

申请日：2021-07-01

申请人： Natals, Inc.

发明人： Luke Bucci ,  Katerina Schneider ,  Mastaneh Sharafi ,  Nima Alamdari

IPC分类号： A61K31/593 ,  A23D9/007 ,  A23L5/00 ,  A23L33/00 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A61K9/16 ,  A61K9/48 ,  A61K31/122 ,  A61K31/202 ,  A61K31/355 ,  A61K31/519 ,  A61K31/714 ,  A61K33/06 ,  A61K33/22 ,  A61K33/26 ,  A61K36/02 ,  A61K36/31 ,  B65D25/54 ,  B65D81/20

CPC分类号： A61K31/593 ,  A23D9/007 ,  A23L5/00 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L33/40 ,  A61K9/1652 ,  A61K9/1664 ,  A61K9/1676 ,  A61K9/4808 ,  A61K31/122 ,  A61K31/202 ,  A61K31/355 ,  A61K31/519 ,  A61K31/714 ,  A61K33/06 ,  A61K33/22 ,  A61K33/26 ,  A61K36/02 ,  A61K36/31 ,  B65D25/54 ,  B65D81/2076 ,  A23V2002/00 ,  B65D2203/12 ,  A23V2002/00 ,  A23V2200/224 ,  A23V2200/30 ,  A23V2250/1572 ,  A23V2250/1592 ,  A23V2250/161 ,  A23V2250/1642 ,  A23V2250/1882 ,  A23V2250/202 ,  A23V2250/5054 ,  A23V2250/51084 ,  A23V2250/702 ,  A23V2250/7056 ,  A23V2250/706 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/714 ,  A23V2002/00 ,  A23V2200/224 ,  A23V2200/30 ,  A23V2250/1572 ,  A23V2250/1592 ,  A23V2250/161 ,  A23V2250/1882 ,  A23V2250/202 ,  A23V2250/5054 ,  A23V2250/51084 ,  A23V2250/7056 ,  A23V2250/706 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/714

摘要： Provided herein are dietary supplement compositions comprising a plurality of beadlets and an oil. Provided herein are also dietary supplement compositions comprising a plurality of mini-tabs and oil. The beadlets or mini-tabs comprise at least one nutrient that is miscible in aqueous solution, and the oil comprises at least one fat-soluble nutrient. The composition may be contained within one or more capsules, and be packaged with a scented insert.

公开(公告)号：US20240325312A1

公开(公告)日：2024-10-03

申请号：US18576218

申请日：2022-07-13

申请人： Incannex Healthcare Limited

发明人： Mark Robert Bleackley ,  Joel Bradley Latham

IPC分类号： A61K9/48 ,  A61K31/00 ,  A61K31/4706 ,  A61P29/00

CPC分类号： A61K9/4808 ,  A61K9/4825 ,  A61K31/4706 ,  A61K31/658 ,  A61P29/00

摘要： The present disclosure relates generally to compositions comprising a synergistic combination of cannabidiol (CBD) or a pharmaceutically acceptable salt or derivative thereof and hydroxychloroquine or a pharmaceutically acceptable salt thereof, which beneficially enables simultaneous administration of the two active pharmaceutical ingredients (APIs) in a single dosage form. In an embodiment, the present disclosure also relates to methods and uses of the composition for the treatment of an inflammatory condition.

公开(公告)号：US20240307315A1

公开(公告)日：2024-09-19

申请号：US18624588

申请日：2024-04-02

申请人： Gel Cap Technologies, LLC

发明人： John PUCKETT

IPC分类号： A61K9/48 ,  A61J3/07 ,  A61K31/00 ,  A61K45/06

CPC分类号： A61K9/4808 ,  A61J3/07 ,  A61J3/074 ,  A61J3/077 ,  A61K9/4833 ,  A61K9/4858 ,  A61K9/4891 ,  A61K31/00 ,  A61K45/06 ,  A61K9/4816

摘要： Capsule forming machines that form a dual dosage capsule have superimposed upper and lower plates that are each rotatable about an axis of rotation. Each of the upper and lower plates define a plurality of voids for receiving a shell body or a capsule member of a capsule that are positioned to define a plurality of stations. A first distribution device is operatively positioned at one of the plurality of stations of each of the upper and lower plates and an actuator is operatively connected to either of the upper or lower plates. The actuator moves the upper plate or the lower plate relative to the other plate and/or pivots the upper plate or the lower plate relative to the other plate transverse to the rotational axis to move a capsule assembly station thereof toward to the other plate and then away from the other plate at predetermined times.

公开(公告)号：US20240299306A1

公开(公告)日：2024-09-12

申请号：US18437368

申请日：2024-02-09

申请人： CHEMOCENTRYX, INC.

发明人： Manmohan Reddy LELETI ,  Jay P. POWERS

IPC分类号： A61K9/48 ,  A61K31/4412

CPC分类号： A61K9/4858 ,  A61K9/4808 ,  A61K9/4825 ,  A61K9/4833 ,  A61K31/4412

摘要： The present disclosure provides solid solution capsule formulations of Compound 1




and methods of making the same. Also provided herein are methods of treating individuals suffering from or susceptible to a disease or disorder involving pathologic activation of C5a receptors by administering an effective amount of one or more solid solution capsules comprising Compound 1. Further provided herein are singe unit dosage capsules comprising certain amounts of Compound 1, and kits comprising a solid solution capsule comprising Compound 1.

公开(公告)号：US20240189224A1

公开(公告)日：2024-06-13

申请号：US18236721

申请日：2023-08-22

申请人： FEDSON, INC.

发明人： Rajesh A. PATEL ,  Sunil SREEDHARAN ,  Sunil R. BHONSLE

IPC分类号： A61K9/00 ,  A61K9/48 ,  A61K31/197 ,  A61K31/4045 ,  A61K31/4458 ,  A61K31/485 ,  A61K31/506 ,  A61K38/26 ,  B29C48/06 ,  B29C48/21 ,  B29K1/00 ,  B29K23/00 ,  B29K105/00 ,  B29L31/00

CPC分类号： A61K9/0024 ,  A61K9/4808 ,  A61K9/4816 ,  A61K9/4833 ,  A61K31/197 ,  A61K31/4045 ,  A61K31/4458 ,  A61K31/485 ,  A61K31/506 ,  A61K38/26 ,  B29C48/06 ,  B29C48/21 ,  B29K2001/08 ,  B29K2023/083 ,  B29K2105/0035 ,  B29K2995/006 ,  B29L2031/753

摘要： The invention provides implantable drug delivery devices comprising a core comprising a polymer (or polymer blend) and one or more drugs or pharmaceutical substances, and an outer shell comprising a polymer (or polymer blend) and one or more porogen materials. The invention reduces burst release of drug. Pharmaceuticals such as triiodothyronine (T3) or ropinirole can be delivered by the devices.

公开(公告)号：US11975107B2

公开(公告)日：2024-05-07

申请号：US17856682

申请日：2022-07-01

申请人： Capsugel Belgium NV

发明人： Hugues Straub ,  Stefaan Jaak Vanquickenborne

IPC分类号： A61K9/48 ,  A23P10/30 ,  A23P30/10 ,  B29C41/00 ,  B29C41/14 ,  B29K1/00 ,  B29K105/00 ,  B29L31/00

CPC分类号： A61K9/4816 ,  A23P10/30 ,  A23P30/10 ,  A61K9/4808 ,  A61K9/4883 ,  B29C41/003 ,  B29C41/14 ,  B29K2001/08 ,  B29K2105/0032 ,  B29K2995/0092 ,  B29L2031/7174

摘要： An aqueous composition for making dip-molded comestible hard capsules comprising a film forming capsule base material and one or more colorants each consisting of a hydrophilic coloring foodstuff concentrate.

公开(公告)号：US20240122920A1

公开(公告)日：2024-04-18

申请号：US18394475

申请日：2023-12-22

申请人： Collegium Pharmaceutical, Inc.

发明人： Said SAIM ,  Alison B. FLEMING ,  Ravi K. VARANASI

IPC分类号： A61K31/485 ,  A61K9/16 ,  A61K9/48 ,  A61K47/12 ,  A61K47/26 ,  A61K47/44

CPC分类号： A61K31/485 ,  A61K9/1617 ,  A61K9/1694 ,  A61K9/4808 ,  A61K9/4833 ,  A61K9/4858 ,  A61K9/4875 ,  A61K47/12 ,  A61K47/26 ,  A61K47/44

摘要： The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.

公开(公告)号：US20240122862A1

公开(公告)日：2024-04-18

申请号：US17766722

申请日：2020-10-13

申请人： Julius-Maximilians-Universitaet Wuerzburg

发明人： Cornelius HERMANN ,  Lorenz MEINEL ,  Wolfgang SCHMEHL ,  Kevin POPP ,  Simon REILAENDER

IPC分类号： A61K9/48 ,  A61K33/04

CPC分类号： A61K9/485 ,  A61K9/4808 ,  A61K9/4816 ,  A61K33/04

摘要： The present invention discloses a therapeutic gas release system for oral administration comprising a therapeutic gas releasing compound A, and a therapeutic gas release triggering compound B, wherein compound A and B are separated from each other by an inner septum during storage of the system, wherein compound A and B are surrounded by an outer membrane, which is a gas-permeable and water- and solid-impermeable membrane, preferably a silicone membrane, and wherein therapeutic gas release from the system is activated before oral administration by breaking the inner septum. The therapeutic gas released from the system of the present invention is suitable for the treatment of (inflammatory) diseases of the gastrointestinal tract.

公开(公告)号：US11944707B2

公开(公告)日：2024-04-02

申请号：US16448074

申请日：2019-06-21

申请人： Gel Cap Technologies, LLC

发明人： John Puckett

IPC分类号： A61K9/48 ,  A61J3/07 ,  A61K31/00 ,  A61K45/06

CPC分类号： A61K9/4808 ,  A61J3/07 ,  A61J3/074 ,  A61J3/077 ,  A61K9/4833 ,  A61K9/4858 ,  A61K9/4891 ,  A61K31/00 ,  A61K45/06 ,  A61K9/4816

摘要： Capsule forming machines that form a dual dosage capsule have superimposed upper and lower plates that are each rotatable about an axis of rotation. Each of the upper and lower plates define a plurality of voids for receiving a shell body or a capsule member of a capsule that are positioned to define a plurality of stations. A first distribution device is operatively positioned at one of the plurality of stations of each of the upper and lower plates and an actuator is operatively connected to either of the upper or lower plates. The actuator lifts and lowers the upper plate or the lower plate relative to the other plate and/or pivots the upper plate or the lower plate relative to the other plate transverse to the rotational axis to move a capsule assembly station thereof toward to the other plate and then away from the other plate at predetermined times.