公开(公告)号：US11911744B2

公开(公告)日：2024-02-27

申请号：US17339416

申请日：2021-06-04

申请人： SIMEON INVESTMENT, INC.

发明人： Lijun Sun

IPC分类号： B01J20/24 ,  A61K31/736 ,  B01J20/30

CPC分类号： B01J20/24 ,  A61K31/736 ,  B01J20/3021 ,  B01J20/3078

摘要： Provided are superabsorbent materials composed of agar, and one or more water-soluble natural polysaccharides, and dietary compositions containing such superabsorbent materials. The disclosed superabsorbent materials have various food and therapeutic applications and can be used as loading vehicles for nutrients and therapeutic agents. Also provided are methods for preparing such superabsorbent materials.

公开(公告)号：US11690801B2

公开(公告)日：2023-07-04

申请号：US17344062

申请日：2021-06-10

申请人： Steven J. Edwards

发明人： Steven J. Edwards

IPC分类号： A61F13/00 ,  A61K9/00 ,  A61K35/742 ,  A61K31/047 ,  A61K35/747 ,  A61K31/736 ,  A61K35/745

CPC分类号： A61K9/006 ,  A61K31/047 ,  A61K31/736 ,  A61K35/742 ,  A61K35/745 ,  A61K35/747

摘要： An oral pharmabiotic system is disclosed for improving oral, dental, and systemic health by repopulating and reshaping the flora within a patient's oral environment in a manner that overcomes the deficiencies of prior oral probiotic products. By formulating the pharmabiotic system as a strip for adhesive placement within a patients' oral cavity, preferably against the buccal mucosa, alveolar mucosa, oral labial mucosa, or a dental appliance, and configuring the parameters of the strip such that neither disadhesion nor complete dissolution occurs for at least a period of at least three hours during daytime use and at least six hours during nighttime use, the probiotic payload contained within may remain in the oral cavity for a sufficient length of time required for the probiotics to activate, replicate, and displace existing harmful oral pathobiotics.

公开(公告)号：US20180133242A1

公开(公告)日：2018-05-17

申请号：US15870199

申请日：2018-01-12

申请人： OmniGen Research, L.L.C.

发明人： James D. Chapman ,  David Calabotta ,  Neil E. Forsberg ,  Steven B. Puntenney

IPC分类号： A61K31/716 ,  A23K50/70 ,  A23K50/30 ,  A61K31/715 ,  A61K33/00 ,  A61K31/736 ,  A61K33/06 ,  A61K35/00 ,  A23K20/163 ,  A23K20/20 ,  A23K20/28 ,  A61K38/47 ,  A23K50/40 ,  A23K50/10 ,  A23K50/20 ,  A61K35/02 ,  A61K45/06

CPC分类号： A61K31/716 ,  A23K20/163 ,  A23K20/20 ,  A23K20/28 ,  A23K50/10 ,  A23K50/20 ,  A23K50/30 ,  A23K50/40 ,  A23K50/70 ,  A61K31/715 ,  A61K31/736 ,  A61K33/00 ,  A61K33/06 ,  A61K35/00 ,  A61K35/02 ,  A61K38/47 ,  A61K45/06 ,  A61K2300/00

摘要： Disclosed herein is a method for promoting reduction of heat stress in animals, as well as a composition for use in the disclosed method. The composition comprises a glucan, silica, mineral clay, mannan, and optionally an endoglucanohydrolase, and may be administered to an animal that is susceptible to or suffers from heat stress.

公开(公告)号：US09943559B2

公开(公告)日：2018-04-17

申请号：US15106409

申请日：2014-12-19

申请人： NESTEC S.A.

发明人： Abby Klosterbuer ,  Zamzam Kabiry (Fariba) Roughead

IPC分类号： A61K36/48 ,  A61K31/733 ,  A61K31/702 ,  A23L29/25 ,  A23L33/10 ,  A23L33/22 ,  A23L33/105 ,  A61K9/00 ,  A61K31/736

CPC分类号： A61K36/48 ,  A23L29/25 ,  A23L33/10 ,  A23L33/105 ,  A23L33/22 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/0095 ,  A61K31/702 ,  A61K31/733 ,  A61K31/736 ,  A23V2200/3202 ,  A23V2250/5022 ,  A23V2250/5028 ,  A23V2250/5046 ,  A23V2250/5062 ,  A61K2300/00

摘要： The present disclosure relates to nutritional compositions containing a fiber blend that includes soluble fibers that are fructo-oligosaccharide (FOS), acacia gum and inulin and also includes insoluble fibers that are outer pea fibers. In an embodiment, the fiber blend includes about 50% soluble fibers and about 50% insoluble fibers, and the soluble fibers are FOS in an amount of about 41% by weight of the soluble fibers, acacia gum in an amount of about 41% by weight of the soluble fibers, and inulin in an amount of about 18% by weight of the soluble fibers. In such an embodiment, the insoluble fibers are outer pea fibers. The present disclosure also relates to methods that include administering a therapeutically effective amount of a fiber blend that includes FOS, acacia gum, inulin and outer pea fibers to a patient after antibiotic treatment.

公开(公告)号：US20180008661A1

公开(公告)日：2018-01-11

申请号：US15623246

申请日：2017-06-14

申请人： Herbalife International, Inc.

发明人： Michael Yatcilla ,  Wenjie Li ,  Andrea Bertocco ,  Joosang Park

IPC分类号： A61K36/886

CPC分类号： A61K36/886 ,  A23L2/02 ,  A23L2/08 ,  A23L2/39 ,  A23L2/52 ,  A23L2/56 ,  A23L2/58 ,  A23L2/68 ,  A23L2/70 ,  A23L2/72 ,  A23L2/80 ,  A23L19/01 ,  A23L29/20 ,  A23L29/206 ,  A23L29/212 ,  A23L29/238 ,  A23L29/25 ,  A23L29/262 ,  A23L29/275 ,  A23L29/294 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/7028 ,  A61K31/736 ,  A61K2236/10 ,  A23V2200/02 ,  A23V2200/324 ,  A23V2250/2102

摘要： Disclosed herein is a method for improving the health of animal or human microflora using aloe vera. A method of purifying decolorized dried aloe vera leaf juice is also disclosed. The method may include removing an aloe vera leaf from an aloe vera plant, washing and/or sanitizing the leaf, and grinding the leaf into a slurry and subsequently purifying with activated carbon. The method may remove pigmented substances including the undesirable phenolic compounds present in aloe vera latex, and in particular the anthrones aloin A and aloin B, aloesin (a chromone) and aloe-emodin (an anthraquinone). Following purification, the liquid juice may then be spray-dried to form a final dry juice powder.

公开(公告)号：US09782431B2

公开(公告)日：2017-10-10

申请号：US14856397

申请日：2015-09-16

申请人： Chang Gung Biotechnology Corp.

发明人： Yun-Fei Ko ,  Jan Martel ,  Jian-Ching Liau ,  I-Te Chang ,  Chien-Sheng Lee ,  Wei-Chang Wang ,  Chen-Yaw Chiu ,  Chih-Jung Chang ,  Chuan-Sheng Lin ,  Tsung-Ru Wu ,  Chia-Chen Lu ,  David Marcelo Ojcius ,  Hsin-Chih Lai ,  Ding-E Young

IPC分类号： A61K31/736 ,  A61K36/062 ,  C08B37/00

CPC分类号： A61K31/736 ,  A61K36/062 ,  A61K45/06 ,  A61K2236/53 ,  C08B37/0003 ,  C08B37/0087

摘要： The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides reduce body weight and fat accumulation in laboratory animals, and can therefore be used to prevent and treat obesity.

公开(公告)号：US09757345B2

公开(公告)日：2017-09-12

申请号：US14430046

申请日：2013-09-20

申请人： ABBOTT LABORATORIES

发明人： Joseph Walton ,  Emily Stepp ,  Amy Devitt-Maicher ,  David Wolf ,  Vikkie Mustad ,  Jeffrey Baxter ,  Terrence Mazer ,  Amy Marchio

IPC分类号： A61K31/19 ,  A61K36/889 ,  A61K38/01 ,  A61K31/202 ,  A61K31/22 ,  A61K33/00 ,  A61K33/42 ,  A61K36/28 ,  A61K36/286 ,  A61K36/31 ,  A61K36/48 ,  A61K9/00 ,  A23L2/38 ,  A23L2/66 ,  A61K31/7004 ,  A61K31/736 ,  A61K33/06 ,  A61K36/899 ,  A61K38/28 ,  A23L33/12 ,  A23L33/16 ,  A23L33/18 ,  A23L33/185 ,  A23L33/19 ,  A23L33/21

CPC分类号： A61K31/19 ,  A23L2/38 ,  A23L2/66 ,  A23L33/12 ,  A23L33/16 ,  A23L33/18 ,  A23L33/185 ,  A23L33/19 ,  A23L33/21 ,  A23V2002/00 ,  A61K9/0095 ,  A61K31/202 ,  A61K31/22 ,  A61K31/7004 ,  A61K31/702 ,  A61K31/715 ,  A61K31/736 ,  A61K33/00 ,  A61K33/06 ,  A61K33/42 ,  A61K36/28 ,  A61K36/286 ,  A61K36/31 ,  A61K36/48 ,  A61K36/889 ,  A61K36/899 ,  A61K38/011 ,  A61K38/018 ,  A61K38/28 ,  A61K2300/00

摘要： Disclosed are nutritional compositions, and methods of using and making the nutritional compositions, that include calcium beta-hydroxy-beta-methylbutyrate and protein. The calcium beta-hydroxy-beta-methylbutyrate is in sequestered or ion-exchanged form to reduce the interaction of the calcium with the protein in the nutritional composition and improve the overall stability of the nutritional composition.

公开(公告)号：US20170224613A1

公开(公告)日：2017-08-10

申请号：US15515409

申请日：2014-09-30

申请人： CHONGQING MJ MEDICAL DEVICES CO., LTD.

发明人： Jun WU ,  Gaoxing LUO ,  Johnson Yiu-Nam LAU ,  Manson FOK ,  Chun-Ho WONG ,  Meinrad FLURY ,  Benjamin Tak-Kwong LEE

IPC分类号： A61K9/00 ,  A61K9/06 ,  A61K47/36 ,  A61K31/736 ,  A61K31/738 ,  A61K9/51 ,  A61K31/045

CPC分类号： A61K9/0014 ,  A61K9/06 ,  A61K9/5161 ,  A61K31/045 ,  A61K31/736 ,  A61K31/738 ,  A61K47/36 ,  A61K2300/00

摘要： Disclosed are hydrogel composition, method for preparing the same and use thereof. The hydrogel composition comprises a guar gum derivative which is crosslinked, a mint-based component, water, and optionally, an amphiphilic core-shell nanoparticle having a hydrophobic core and a hydrophilic shell, wherein the amount of the mint-based component is in the range of 1-6 wt % and the amount of the water is in the range of 65-95 wt %, based on the total weight of the hydrogel composition. The hydrogel composition is safe and can provide symptomatic relief for patients with symptoms such as severe and intractable pruritus associated with hypertrophic scars. The symptomatic relief effect of the hydrogel composition is reproducible, and is independent of the etiology of the burn trauma, extent of the scarring and duration of the scar formation, while tachyphylaxis is not observed. Also disclosed is a medical device comprising the hydrogel composition.

公开(公告)号：US20170028011A1

公开(公告)日：2017-02-02

申请号：US15303021

申请日：2015-04-12

申请人： MARMAR INVESTMENT SP. Z O.O.

发明人： Marek ORLOWSKI ,  Marcin KROTKIEWSKI ,  Katarzyna BILLING-MARCZAK

IPC分类号： A61K36/74 ,  A61K36/48 ,  A61K31/7004 ,  A61K31/736 ,  A61K31/733 ,  A23L33/21 ,  A61K9/08 ,  A23L2/52 ,  A23L7/109 ,  A23L23/00 ,  A23L33/105 ,  A61K36/605 ,  A61K9/00

CPC分类号： A61K36/74 ,  A23L2/52 ,  A23L7/109 ,  A23L23/00 ,  A23L33/105 ,  A23L33/21 ,  A23L33/30 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/08 ,  A61K31/7004 ,  A61K31/733 ,  A61K31/736 ,  A61K36/48 ,  A61K36/605 ,  A61K47/46 ,  A61K2300/00

摘要： The present invention provides dietary compositions comprising mulberry extract, coffee extract, bean extract, optionally, dietary fibers, and a nutraceutically acceptable carrier. The present invention further provides methods for preventing the increase in postprandial hyperglycemia and hypoglycemia, hyperinsulinemia and diseases and disorders associated therewith, including, endothelial dysfunction, inflammatory conditions, oxidative stress, hyperlipidemia, and consecutive pathologies like insulin resistance, diabetes, visceral obesity, hypertension and cardiovascular diseases.

摘要翻译： 本发明提供了包含桑叶提取物，咖啡提取物，豆提取物，任选的膳食纤维和营养可接受的载体的饮食组合物。 本发明还提供了防止餐后高血糖和低血糖，高胰岛素血症及其相关疾病和病症增加的方法，包括内皮功能障碍，炎性病症，氧化应激，高脂血症和连续病理如胰岛素抵抗，糖尿病，内脏肥胖，高血压 和心血管疾病。

公开(公告)号：US20160346314A1

公开(公告)日：2016-12-01

申请号：US15234971

申请日：2016-08-11

申请人： OmniGen Research, L.L.C. ,  The Arizona Board of Regents on Behalf of the University of Arizona

发明人： James D. Chapman ,  David Calabotta ,  Neil E. Forsberg ,  Steven B. Puntenney ,  Robert Collier ,  Laun Hall

IPC分类号： A61K31/716 ,  A61K35/02 ,  A61K31/736 ,  A61K45/06 ,  A23K50/30 ,  A23K20/28 ,  A23K50/70 ,  A23K50/10 ,  A23K50/20 ,  A23K50/40 ,  A61K33/00 ,  A23K20/163

CPC分类号： A61K31/716 ,  A23K20/163 ,  A23K20/20 ,  A23K20/28 ,  A23K50/10 ,  A23K50/20 ,  A23K50/30 ,  A23K50/40 ,  A23K50/70 ,  A61K31/715 ,  A61K31/736 ,  A61K33/00 ,  A61K33/06 ,  A61K35/00 ,  A61K35/02 ,  A61K38/47 ,  A61K45/06 ,  A61K2300/00

摘要： Disclosed herein is a method for promoting reduction of heat stress in animals, as well as a composition for use in the disclosed method. The composition comprises a glucan, silica, mineral clay, mannan, and optionally an endoglucanohydrolase, and may be administered to an animal that is susceptible to or suffers from heat stress.