公开(公告)号：US20240307466A1

公开(公告)日：2024-09-19

申请号：US18589142

申请日：2024-02-27

申请人： Pendulum Therapeutics, Inc.

发明人： Colleen Cutcliffe ,  John S. Eid ,  James H. Bullard ,  Marcus F. Schicklberger

IPC分类号： A61K35/745 ,  A23L33/135 ,  A61K9/00 ,  A61K9/28 ,  A61K9/48 ,  A61K31/00 ,  A61K31/733 ,  A61K35/00 ,  A61K35/74 ,  A61K35/741 ,  A61K35/742 ,  A61K45/06 ,  C12N1/20 ,  C12Q1/689 ,  G01N33/66

CPC分类号： A61K35/745 ,  A23L33/135 ,  A61K9/0053 ,  A61K9/2846 ,  A61K9/48 ,  A61K9/4816 ,  A61K9/4891 ,  A61K31/00 ,  A61K31/733 ,  A61K35/74 ,  A61K35/741 ,  A61K35/742 ,  A61K45/06 ,  C12N1/20 ,  C12Q1/689 ,  G01N33/66 ,  A23V2002/00 ,  A61K2035/115 ,  G01N2333/605 ,  G01N2800/04

摘要： The present disclosure provides methods, systems, compositions, and kits to address the need for microbiome-related treatment of health conditions and disease. The present disclosure provides for treatment of metabolic conditions using microbial compositions.

公开(公告)号：US11938107B1

公开(公告)日：2024-03-26

申请号：US16120205

申请日：2018-08-31

申请人： BIOVET, S.A.

发明人： Jaime Valls Borrell

IPC分类号： A61K36/00 ,  A23K10/30 ,  A23K40/10 ,  A23K50/75 ,  A61K9/00 ,  A61K31/05 ,  A61K31/198 ,  A61K31/733 ,  A61K36/28 ,  A61K36/53 ,  A61K36/88 ,  A61K47/44 ,  A61P33/00

CPC分类号： A61K31/198 ,  A23K10/30 ,  A23K40/10 ,  A23K50/75 ,  A61K9/0056 ,  A61K31/05 ,  A61K31/733 ,  A61K36/28 ,  A61K36/53 ,  A61K36/88 ,  A61K47/44 ,  A61P33/00

摘要： A production procedure for procedure for Alquernat Coneb, a poultry feed (broiler breeders and turkeys) based on alliin, carvacrol, cimenol and inulin from vegetable extracts, and its use in the prevention of parasitic infestations.

公开(公告)号：US20240024353A1

公开(公告)日：2024-01-25

申请号：US18476119

申请日：2023-09-27

申请人： Longevica Therapeutics Inc.

发明人： Alexey Ryazanov ,  Alexander Chikunov ,  Yuriy Shymkiv

IPC分类号： A61K31/733 ,  A61K33/06 ,  A23L33/105 ,  A61K31/194 ,  A61K31/198 ,  A61K31/216 ,  A61K33/14 ,  A61K45/06

CPC分类号： A61K31/733 ,  A61K33/06 ,  A23L33/105 ,  A61K31/194 ,  A61K31/198 ,  A61K31/216 ,  A61K33/14 ,  A61K45/06 ,  A23V2002/00 ,  A23V2250/032 ,  A23V2250/161 ,  A23V2250/21 ,  A23V2250/5062 ,  A61K2300/00

摘要： The present invention relates to methods for attenuating aging, of health maintenance, and/or treating, or delaying the onset of, an age-related condition or disorder, in a subject comprising administering to the subject an effective amount of (a) one or more compounds that sustain pharmacological activation of xenobiotic metabolism or induce fermentation by gut bacteria to produce substances that activate xenobiotic metabolism enzymes and/or stimulate xenobiotic excretion and (b) one or more chelators. A further aspect of the invention is a composition comprising (a) and (b).

公开(公告)号：US11878040B2

公开(公告)日：2024-01-23

申请号：US17823530

申请日：2022-08-31

申请人： GlaxoSmithKline Consumer Healthcare S.R.L.

发明人： Valeria Longoni ,  Marisa Penci

IPC分类号： A61K35/745 ,  A23L33/135 ,  A23L33/16 ,  A23L33/19 ,  A23L33/21 ,  A61K35/747 ,  A61K38/06 ,  A61K38/40 ,  A61K9/00 ,  A61K47/26 ,  A61K47/42 ,  A61K47/20 ,  A61K31/733 ,  A61K47/02 ,  A61K36/064 ,  A61K47/36 ,  A61K35/00

CPC分类号： A61K35/745 ,  A23L33/135 ,  A23L33/16 ,  A23L33/19 ,  A23L33/21 ,  A61K9/0095 ,  A61K31/733 ,  A61K35/747 ,  A61K36/064 ,  A61K38/063 ,  A61K38/40 ,  A61K47/02 ,  A61K47/20 ,  A61K47/26 ,  A61K47/36 ,  A61K47/42 ,  A23V2002/00 ,  A61K2035/11 ,  A61K35/745 ,  A61K35/747 ,  A61K38/06 ,  A61K38/40

摘要： The present invention relates to compositions comprising probiotic and prebiotic components, mineral salts, lactoferrin, and possibly saccharomycetes, which perform correct, effective colonisation of the probiotic components administered, with enteric consequences which involve maintaining and/or restoring intestinal health and preventing the consequences of common dysbioses of the digestive tract caused by stress, incorrect dietary habits and antibiotic treatments. Said compositions also have a concomitant anti-inflammatory and immunomodulating action.

公开(公告)号：US20240000869A1

公开(公告)日：2024-01-04

申请号：US18252804

申请日：2021-11-12

申请人： SYNBIOTICS AB

发明人： Catharina LAVEBRATT ,  Joëlle RÜEGG ,  Martin SCHALLING

IPC分类号： A61K35/747 ,  A61K31/716 ,  A61K31/732 ,  A61K31/733 ,  A61K31/718 ,  A61P25/26 ,  A61P25/24

CPC分类号： A61K35/747 ,  A61K31/716 ,  A61K31/732 ,  A61K31/733 ,  A61K31/718 ,  A61P25/26 ,  A61P25/24 ,  A61K2035/115

摘要： A synbiotic composition for use in the amelioration, treatment, reductions of symptoms of a neuropsychiatric disorder and/or the reduction of side effects of a pharmacological treatment of a neuropsychiatric disorder. The synbiotic composition includes at least two bacterial strains chosen from the group consisting of Lactobacillus plantarum, Lactobacillus paracasei, Pediococcus pentosaceus, Leuconostoc mesenteroides, and Bifidobacterium breve; and at least one dietary fibers chosen from the group consisting of inulin, pectin, beta-glucan, resistant starch, a galacto-oligosaccharide, an isomalto-oligosaccharide and a rice fiber.

公开(公告)号：US20230233643A1

公开(公告)日：2023-07-27

申请号：US17674834

申请日：2022-02-17

申请人： TCI CO., LTD.

发明人： YUNG-HSIANG LIN ,  CHU-HAN HUANG

IPC分类号： A61K36/87 ,  A61K31/702 ,  A61K31/733 ,  A61K31/7032 ,  A61P1/14

CPC分类号： A61K36/87 ,  A61K31/702 ,  A61K31/733 ,  A61K31/7032 ,  A61P1/14 ,  A61K2236/19

摘要： Prebiotic composition including grape ferment, a first component, and a second component is provided. The first component is lactitol or xylooligosaccharide, and the second component is fructooligosaccharide, xylooligosaccharide, or inulin. The first component is different from the second component, and a weight ratio of the grape ferment, the first component and the second component falls within the range of 1-2:1-2:1-2. Based on this, the prebiotic composition prepared by grape ferment can be used to promote intestinal health of a subject in need thereof and enhance antioxidation in the subject.

公开(公告)号：US11547744B2

公开(公告)日：2023-01-10

申请号：US16315132

申请日：2017-07-06

申请人： Building Block Nutritionals, LLC

发明人： James McGrath ,  Paul Manning ,  Eugene Scavola

IPC分类号： A61K38/38 ,  A23L33/12 ,  A23L33/26 ,  A23L33/125 ,  A23L33/18 ,  A23L33/19 ,  A23L33/00 ,  A23L33/17 ,  A23L33/10 ,  A23L33/115 ,  A23L33/13 ,  A23L33/16 ,  A23L33/155 ,  A61K9/00 ,  A61K31/015 ,  A61K31/05 ,  A61K31/122 ,  A61K31/14 ,  A61K31/185 ,  A61K31/194 ,  A61K31/197 ,  A61K31/201 ,  A61K31/202 ,  A61K31/203 ,  A61K31/205 ,  A61K31/355 ,  A61K31/375 ,  A61K31/4188 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/593 ,  A61K31/685 ,  A61K31/7004 ,  A61K31/7016 ,  A61K31/702 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  A61K31/708 ,  A61K31/714 ,  A61K31/718 ,  A61K31/733 ,  A61K33/00 ,  A61K33/04 ,  A61K33/14 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61K33/42 ,  A61K38/17 ,  A61K38/40

摘要： The present disclosure provides a nutritional formula comprising alpha-lactalbumin enriched whey protein concentrate; beta-casein enriched milk protein; mildly hydrolyzed milk protein; osteopontin; lactoferrin; oleic acid-palmitic acid-oleic acid triglyceride, wherein palmitic acid is at the SN-2 position of the glycerol backbone of the triglyceride; lactose, wherein the lactose is reduced lactose; lutein; docosahexanoic acid; arachidonic acid; galactooligosaccharides; and polydextrose. The provided nutritional formulas may be useful in providing nutrition and/or promoting postnatal development of a subject (e.g., promoting postnatal development of an infant's gastrointestinal functions, nutrient absorption, immune system development, etc.). Also provided are powder forms, reconstituted formulas, kits, methods, and uses that include or involve a nutritional formula described herein.

公开(公告)号：US20210386798A1

公开(公告)日：2021-12-16

申请号：US17411983

申请日：2021-08-25

申请人： Pendulum Therapeutics, Inc.

发明人： Colleen CUTCLIFFE ,  John S. EID ,  James H. BULLARD ,  Marcus F. SCHICKLBERGER

IPC分类号： A61K35/745 ,  A23L33/135 ,  A61K45/06 ,  A61K35/74 ,  C12N1/20 ,  A61K31/00 ,  A61K9/00 ,  A61K9/28 ,  A61K9/48 ,  A61K31/733 ,  A61K35/741 ,  A61K35/742 ,  C12Q1/689 ,  G01N33/66

摘要： The present disclosure provides methods, systems, compositions, and kits to address the need for microbiome-related treatment of health conditions and disease. The present disclosure provides for treatment of metabolic conditions using microbial compositions.

公开(公告)号：US20210283173A1

公开(公告)日：2021-09-16

申请号：US17328624

申请日：2021-05-24

申请人： Longevica Therapeutics Inc.

发明人： Alexey Ryazanov ,  Alexander Chikunov ,  Yuriy Shymkiv

IPC分类号： A61K31/733 ,  A61K33/06 ,  A23L33/105 ,  A61K31/194 ,  A61K31/198 ,  A61K31/216 ,  A61K33/14 ,  A61K45/06

摘要： The present invention relates to methods for attenuating aging, of health maintenance, and/or treating, or delaying the onset of, an age-related condition or disorder, in a subject comprising administering to the subject an effective amount of (a) one or more compounds that sustain pharmacological activation of xenobiotic metabolism or induce fermentation by gut bacteria to produce substances that activate xenobiotic metabolism enzymes and/or stimulate xenobiotic excretion and (b) one or more chelators. A further aspect of the invention is a composition comprising (a) and (b).

公开(公告)号：US11058649B2

公开(公告)日：2021-07-13

申请号：US16384546

申请日：2019-04-15

申请人： Mark Tuffley

发明人： Mark Tuffley

IPC分类号： A61K31/155 ,  A61K31/375 ,  A61K31/51 ,  A61K31/525 ,  A61K33/18 ,  A61K33/24 ,  A61K45/06 ,  A61K31/164 ,  A61K31/185 ,  A61K31/198 ,  A61K31/205 ,  A61K31/4188 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/519 ,  A61K31/714 ,  A61K33/04 ,  A61K33/06 ,  A61K33/10 ,  A61K33/14 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61K9/00 ,  A61K31/145 ,  A61K31/19 ,  A61K31/197 ,  A61K31/555 ,  A61K31/59 ,  A61K31/7004 ,  A61K31/733 ,  A61K33/00

摘要： The invention relates to a composition for enhancing wound healing and/or for reducing pain and inflammation, comprising a first active ingredient and a second active ingredient, wherein the first active ingredient comprises an antiseptic and the second active ingredient comprises an admixture of at least one vitamin, at least one mineral and at least one amino acid, and to use of the composition for enhancing wound healing.