公开(公告)号：US20250018000A1

公开(公告)日：2025-01-16

申请号：US18902831

申请日：2024-09-30

Applicant: BEIJING WEHAND-BIO PHARMACEUTICAL CO., LTD ,  GUANGXI WEHAND-BIO PHARMACEUTICAL CO., LTD

Inventor： Yuling LIU ,  Jun YE ,  Dongdong LIU ,  Hongliang WANG ,  Mo WANG ,  Renjie LI ,  Yanfang YANG

IPC: A61K36/605 ,  A61P1/04

Abstract: The invention discloses a use of a mulberry (Morus alba L.) extract, including a method for treating ulcerative colitis, a method for preventing ulcerative colitis, and a method for reduction in Disease Activity Index, DAI. The use is application of a mulberry extract to the preparation of a product for treating and/or preventing ulcerative colitis. The invention experimentally demonstrated that positive drug group, SZ-A-1, SZ-A-2, SZ-A-3, SZ-A-4 and SZ-A-5 (pretreatment) could each significantly inhibit colonic atrophy in UC model mice, and the effects in SZ-A-2, SZ-A-3 and SZ-A-4 groups are comparable to that in positive drug group, with SZ-A-5 (pretreatment) achieving a superior effect to the positive drug. The mulberry extract of the invention, as a component derived from natural plants, has unique advantages of small toxic and side effects, mild and lasting actions etc.

公开(公告)号：US20240382546A1

公开(公告)日：2024-11-21

申请号：US18636644

申请日：2024-04-16

Applicant: Jihwan KIM

Inventor： Jihwan KIM

IPC: A61K36/258 ,  A61K36/33 ,  A61K36/45 ,  A61K36/484 ,  A61K36/605 ,  A61K36/725 ,  A61K36/8962 ,  A61K36/906

Abstract: The present invention relates to a method of preparing fermented herbal eye drops, and the method includes an herbal medicine washing process of mixing an herbal medicine mixture, vinegar, and coarse salt in purified water, allowing it to stand, and then washing it; a heating process of inputting the herbal medicine mixture washed through the herbal medicine washing process into a decoction pot, mixing the herbal medicine mixture with purified water, and heating the herbal medicine mixture mixed with purified water; a cooling and fermentation process of cooling decoction prepared through the heating process and then fermenting the decoction; an eye drop raw material extraction process of distilling a fermented product prepared through the cooling and fermentation process to extract raw materials for eye drops; and an alkaline water mixing process of mixing alkaline water with the raw materials for eye drops prepared through the eye drop raw material extraction process. The fermented herbal eye drops prepared through the above process do not contain chemical components, have low cytotoxicity, are safe for the human body, and have an excellent sterilizing effect, thereby improving eye diseases such as inflammation or redness.

公开(公告)号：US20230293616A1

公开(公告)日：2023-09-21

申请号：US17914407

申请日：2021-03-25

Applicant: BEIJING UNIVERSITY OF CHINESE MEDICINE THIRD AFFILIATED HOSPITAL

Inventor： Chengxiang WANG ,  Hongsheng CUI ,  Weiheng CHEN ,  Huiyong YU ,  Jianjun WU

IPC: A61K36/344 ,  A61K36/284 ,  A61K36/076 ,  A61K36/8968 ,  A61K36/79 ,  A61K36/73 ,  A61K36/535 ,  A61K36/605 ,  A61K36/346 ,  A61K36/736 ,  A61K36/484

CPC classification number: A61K36/344 ,  A61K36/284 ,  A61K36/076 ,  A61K36/8968 ,  A61K36/79 ,  A61K36/73 ,  A61K36/535 ,  A61K36/605 ,  A61K36/346 ,  A61K36/736 ,  A61K36/484 ,  A61K2236/15 ,  A61K2236/39

Abstract: A traditional Chinese medicine composition for recovery phase of exogenous fever and a preparation method therefor. The traditional Chinese medicine composition comprises the following raw materials: radix codonopsis, rhizoma atractylodis macrocephalae, poria cocos, radix ophiopogonis, schisandra chinensis, hairyvein agrimony, perilla seeds, cortex moriradicis, folium eriobotryae, radix platycodi, apricot kernels, and radix glycyrrhizae. According to the monarch, minister, assistant and guide theory of traditional Chinese medicines, the radix codonopsis is used as a monarch drug; fried rhizoma atractylodis macrocephalae, the poria cocos, the radix ophiopogonis, the schisandra chinensis, and the hairyvein agrimony are used as minister drugs; the perilla seeds, the cortex moriradicis, and the folium eriobotryae are used as assistant drugs; and the radix platycodi, the apricot kernels, and the radix glycyrrhizae are used as guide drugs. Also disclosed is use of the traditional Chinese medicine composition for rehabilitation treatment of novel coronavirus pneumonia and other exogenous fever in the recovery phase.

公开(公告)号：US11730749B2

公开(公告)日：2023-08-22

申请号：US15973501

申请日：2018-05-07

Applicant: Plexus Worldwide, LLC.

Inventor： Stephen Roman ,  Tianan Jiang ,  Marco Rebaza

IPC: A61K31/702 ,  A61K36/74 ,  A61K36/605 ,  A61K36/38 ,  A61K31/385 ,  A61K31/216

CPC classification number: A61K31/702 ,  A61K31/216 ,  A61K31/385 ,  A61K36/38 ,  A61K36/605 ,  A61K36/74 ,  A61K36/74 ,  A61K2300/00

Abstract: Various embodiments of a gut microbiome modulating composition comprises a blend of a polyphenol and an oligosaccharide. Various embodiments of the polyphenol may comprise at least approximately 5% by weight chlorogenic acid. Various embodiments of the oligosaccharides may be standardized to a degree of polymerization of at least three to reduce digestibility. Administration of an effective amount of the gut microbiome modulating composition to a person or animal may stimulate the growth of at least one of Akkermansia muciniphila, Lactobacillus, and Bifidobacterium bacteria in the colon, which may reduce permeability of the colon, increases short chain fatty acid production in the colon, and/or modulate causes immunomodulation of human colon cells. The gut microbiome modulating composition may provide protective effects against obesity-related chronic diseases.

公开(公告)号：US20230201295A1

公开(公告)日：2023-06-29

申请号：US18084009

申请日：2022-12-19

Applicant: Unigen, Inc.

Inventor： Qi Jia ,  Ping Jiao ,  Mesfin Yimam ,  Teresa Horm

IPC: A61K36/605 ,  A61K31/7034 ,  A61K36/48 ,  A61K31/352 ,  A61K31/353

CPC classification number: A61K36/605 ,  A61K31/7034 ,  A61K36/48 ,  A61K31/352 ,  A61K31/353 ,  A61K2300/00

Abstract: Compositions and methods for bone health, cartilage health or both, are disclosed that include preparing and utilizing a mixture of at least one Morus extract enriched for one or more prenylated flavonoids, at least one Scutellaria extract enriched for one or more free-B-ring flavonoids, and at least one Acacia extract enriched for one or more flavans.

公开(公告)号：US20210330730A1

公开(公告)日：2021-10-28

申请号：US17120207

申请日：2020-12-13

Applicant: Jinchang Ai

Inventor： Jinchang Ai

IPC: A61K36/73 ,  A61K36/899 ,  A61K36/11 ,  A61K36/258 ,  A61K36/53 ,  A61K36/605 ,  A61K36/82 ,  A61K36/185 ,  A61K36/288

Abstract: The application discloses a traditional Chinese medicine composition for treating of type 2 diabetes, comprising the following raw materials: wild Descolor Cinquefoil Herb, wild Rhizoma imperatae, wild Root and Rhizome of Japanese Climbing Fern, Ginseng leaf (over 7 years), wild Rough Melic, wild Vitex negundo L., Morus alba L., green tea, wild auricularia, corn silk, dandelion root. The traditional Chinese medicine composition of the application is suitable for patients with type 2 diabetes and complications of type 2 diabetes, which has no adverse reactions and stable curative effect.

公开(公告)号：US20210283158A1

公开(公告)日：2021-09-16

申请号：US16477052

申请日：2018-01-17

Applicant: SAFENAT S.R.L.

Inventor： Francesco Paolo BONINA

IPC: A61K31/7048 ,  A61K31/7034 ,  A61K36/899 ,  A61K36/752 ,  A61K36/605 ,  A61K36/73 ,  A61K36/63 ,  A61K36/80 ,  A61P27/02

Abstract: The present invention relates to nutraceutical or pharmaceutical compositions based on a combination of cyanidin-3-O-glucoside and verbascoside, or extracts of plant origin enriched in the two active ingredients, with a protective action on eyesight.

公开(公告)号：US20210227866A1

公开(公告)日：2021-07-29

申请号：US17011462

申请日：2020-09-03

Applicant: Melaleuca, Inc.

Inventor： Jeremy Ivie

IPC: A23L33/105 ,  A61K36/00 ,  A23L33/16 ,  A23L2/39 ,  A23L2/52 ,  A61K33/24 ,  A61K36/258 ,  A61K36/39 ,  A61K36/54 ,  A61K36/605 ,  A61K36/82 ,  A23L33/10 ,  A23L33/19 ,  A23L33/115 ,  A23L33/125 ,  A23L33/185 ,  A23L2/56 ,  A23L2/66

Abstract: This document provides dietary supplement compositions as well as methods for using dietary supplement compositions to control glucose levels. For example, a dietary supplement composition including chromium (e.g., Chromium Oligofructose Complex), a sweet potato extract, and one or more of a mulberry extract, a green tea extract, a cinnamon extract, or a ginseng extract (e.g., Korean Red Ginseng extract) are provided.

公开(公告)号：US10757961B2

公开(公告)日：2020-09-01

申请号：US16231200

申请日：2018-12-21

Applicant: WORLD PHARMACEUTICAL TECHNOLOGY, LLC.

Inventor： Yong Wu ,  Wei Cao ,  Jieqing Li ,  Huabing Yang ,  Ke Wu ,  Shiliu Tian

IPC: A61K31/375 ,  A23L33/105 ,  A23L33/16 ,  A61K36/481 ,  A61K36/73 ,  A61K36/605 ,  A61K36/63 ,  A61K36/42 ,  A61K31/4188 ,  A61K9/00 ,  A61P3/10 ,  A23L33/15

Abstract: A formulation for a dietary supplement includes standardized extracts of Astragalus root, phlorizin, root bark of white mulberry, olive leaf, and bitter melon. The formulation may further include chromium, 2-deoxy-D-glucose, biotin, vitamin D and vitamin C. A method of controlling postprandial blood glucose includes administering the formulation for the dietary supplement to a patient.

公开(公告)号：US20200206292A1

公开(公告)日：2020-07-02

申请号：US16812899

申请日：2020-03-09

Applicant: Unigen, Inc.

Inventor： Qi Jia ,  Ping Jiao ,  Mesfin Yimam ,  Teresa Horm

IPC: A61K36/605 ,  A61K31/352 ,  A61K36/48 ,  A61K31/7034 ,  A61K31/353

Abstract: Compositions and methods for bone health, cartilage health or both, are disclosed that include preparing and utilizing a mixture of at least one Morus extract enriched for one or more prenylated flavonoids, at least one Scutellaria extract enriched for one or more free-B-ring flavonoids, and at least one Acacia extract enriched for one or more flavans.