公开(公告)号：US20240398887A1

公开(公告)日：2024-12-05

申请号：US18799967

申请日：2024-08-09

Applicant: Beijing Chuanglian Huitong Biotechnology Co., Ltd.

Inventor： Jing Wang

IPC: A61K36/88 ,  A61K36/232 ,  A61K36/258 ,  A61K36/80

Abstract: The present invention discloses a traditional Chinese medicine composition for tonifying qi and nourishing blood. The traditional Chinese medicine composition includes, by mass, the following components: 8-12 parts of saffron, 200-300 parts of Chinese angelica, 200-300 parts of ginseng, 200-300 parts of pipewort, and 200-300 parts of butterflybush flowers. The traditional Chinese medicine composition is used for eye care and health protection. The traditional Chinese medicine composite is applicable to symptoms including: dry eyes, astringent eyes, itchy eyes, eyestrain, foreign body sensation, pterygium, blurred vision, photophobia, epiphora induced by wind, macular degeneration, prevention of myopia, conjunctival concretion, and cataracts. The traditional Chinese medicine composition for tonifying qi and nourishing blood provided by the present invention is extracted from pure traditional Chinese medicines without hormones or irritation and is used by means of atomizing with cool feeling; the provided traditional Chinese medicine composition is capable of dredging meridians around an eye, improving a blood supply of the eye, removing congestion, tonifying qi, and nourishing blood, thus improving an self-healing ability of eye tissue and repairing a damaged optic nerve. On the basis of practice of 5,000-year-long traditional Chinese medicine ophthalmology culture, the inventor believes that the eye can see things clearly based on enriched blood. The provided traditional Chinese medicine composition has advantages of being simple, comfortable and convenient to use.

公开(公告)号：US20220000964A1

公开(公告)日：2022-01-06

申请号：US17169490

申请日：2021-02-07

Applicant: Unigen, Inc.

Inventor： Mesfin Yimam ,  Mei Hong ,  Ping Jiao ,  Teresa Horm ,  Kelly Dawkins ,  Alexandria O'Neal ,  Qi Jia

IPC: A61K36/9062 ,  A61K36/575 ,  A61K36/21 ,  A61K36/19 ,  A61K36/80 ,  A61K36/25 ,  A61K36/13 ,  A61K36/282 ,  A61K36/75 ,  A61K36/57 ,  A61K36/185 ,  A61K36/53 ,  A61K36/67 ,  A61K31/05 ,  A61K31/352 ,  A61K31/12 ,  A61K36/906 ,  A61K35/60 ,  A61K36/82 ,  A61K36/87 ,  A61K31/165 ,  A61K31/375 ,  A61K31/593 ,  A61K31/355 ,  A61P19/02

Abstract: Medicinal plant extracts and their bioactives from Alpinia, Magnolia, Kochia and Piper/Pepper are disclosed herein in combination or alone in regulating homeostasis of chondrocytes, extracellular matrix, articular cartilage, and phenotype of arthritis that lead to enhanced anabolic functions of chondrocytes, increased renewal/rebuilding/regeneration of extracellular matrix and articular cartilage, and improved phenotype of osteoarthritis and rheumatoid arthritis.

公开(公告)号：US10912742B2

公开(公告)日：2021-02-09

申请号：US16330676

申请日：2017-09-07

Applicant: The University of Sydney

Inventor： Colin Charles Duke ,  Rujee Kyokajee Duke ,  Van Hoan Tran

IPC: A61K31/122 ,  A61P35/02 ,  A61K31/05 ,  A61K31/352 ,  A61K36/80 ,  C07C69/18 ,  A61P17/00 ,  A61K47/26 ,  C07C43/196 ,  C07C50/14 ,  A61P31/00 ,  C07C69/78 ,  C07C39/23 ,  C07C39/38 ,  A61P25/00 ,  C07C50/20 ,  C07D311/92 ,  A61P3/00 ,  A61P35/00 ,  A61K47/32 ,  C07C69/017 ,  A61K9/00

Abstract: The invention relates to terpenes and uses thereof.

公开(公告)号：US10406136B2

公开(公告)日：2019-09-10

申请号：US14908544

申请日：2014-07-25

Applicant: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY ,  GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ki Hun Park ,  Soo Hyun Eom ,  Young Bae Ryu ,  Jung Keun Cho

IPC: A61K36/00 ,  A61K31/353 ,  A61K36/80 ,  A61K36/185 ,  A61K45/06

Abstract: The present invention relates to a composition for suppressing neuraminidase activity comprising a geranylated flavonoid derived from Paulownia tomentosa as an active ingredient. The Paulownia tomentosa extract and the geranylated flavonoid isolated therefrom exhibit an effect in significantly suppressing neuraminidase, which is an enzyme that plays an important role in the occurrence of pathogenic viral and bacterial infections and of the inflammation that accompanies such infection, and thus the Paulownia tomentosa extract or the geranylated flavonoid isolated therefrom can advantageously be used as an active ingredient in a composition for inhibiting neuraminidase activity.

公开(公告)号：US20190247456A1

公开(公告)日：2019-08-15

申请号：US16336876

申请日：2016-09-27

Applicant: Beijing Zhendong Guangming Pharmaceutical Research Institute Co., LTD

Inventor： Siju ZHANG ,  Jinhua WANG ,  Wenjie QIN ,  Xiaoning YANG ,  Juanjuan LIANG ,  Hongjiang HAO ,  Hongyu WANG

IPC: A61K36/70 ,  A61K36/489 ,  A61K36/80 ,  A61K36/71 ,  A61P17/06

CPC classification number: A61K36/70 ,  A61K36/282 ,  A61K36/48 ,  A61K36/489 ,  A61K36/71 ,  A61K36/80 ,  A61K2236/333 ,  A61K2236/51 ,  A61K2236/53 ,  A61P17/06

Abstract: The invention relates to the field of traditional Chinese medicine, in particular to provides traditional Chinese medicine compositions for the treatment of psoriasis, their preparations and their preparation methods. The Chinese medicine compositions of the invention are consisted of 20-80 parts of Rumex madaio, 20-80 parts of Radix sophora flavescens, 10-50 parts of Herba Siphonostegiae, 10-40 parts of Chinese pulsatilla chinensis, and 5-30 parts of Acacia catechu, by weight. The invention also includes the preparation methods of the traditional Chinese medicine compositions and the preparations containing the traditional Chinese medicine compositions and method for preparing the same. The pharmacological experiments and clinical experiments proved that the traditional Chinese medicine compositions of the invention have remarkable curative effects on psoriasis vulgaris, high cure rate, no toxic and side effects of hormones, and is suitable for the characteristics of psoriasis having long-term use due to the long-course of the diseases.

公开(公告)号：US10137164B2

公开(公告)日：2018-11-27

申请号：US14986846

申请日：2016-01-04

Applicant: Melaleuca, Inc.

Inventor： Alexander B. Rabovsky ,  Stephanie Y. Nielson

IPC: A61K36/9066 ,  A61K36/68 ,  A61K36/185 ,  A61K36/80 ,  A61K9/20 ,  A61K9/48 ,  A61K31/12 ,  A61K31/14 ,  A61K31/355 ,  A61K31/4748 ,  A61K31/519 ,  A61K31/221 ,  A23L33/10 ,  A23L33/105 ,  A23L33/15 ,  A23L33/175

Abstract: This document provides dietary supplement compositions. For example, dietary supplement compositions having an acetylcholinesterase inhibitor (e.g., huperzine A), a Bacopa monnieri extract, acetyl-L-carnitine or acetyl CoA, and a curcuminoid (e.g., curcumin) are provided.

公开(公告)号：US09592263B2

公开(公告)日：2017-03-14

申请号：US14653852

申请日：2013-12-23

Applicant: YUNGJIN PHARMACEUTICAL CO., LTD ,  KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

Inventor： Yongnam Lee ,  Ji-seok Yoo ,  Dae-hee Shin ,  Byung-hwan Ryoo ,  Sei-ryang Oh ,  Kyung-seop Ahn ,  Hyeongkyu Lee ,  Ok-kyoung Kwon ,  Doo-young Kim ,  Jung-hee Kim ,  Hyuk-hwan Song

IPC: A61K36/00 ,  A61K36/68 ,  A61K36/80 ,  A23L1/29 ,  A61K31/192 ,  A61K31/7048

CPC classification number: A61K36/68 ,  A23L1/296 ,  A23L27/10 ,  A23L33/105 ,  A23V2002/00 ,  A61K9/0056 ,  A61K31/192 ,  A61K31/7048 ,  A61K36/80 ,  A61K2236/15 ,  A61K2236/33 ,  A61K2236/331 ,  A61K2236/333 ,  A61K2236/39 ,  A61K2236/51 ,  A61K2236/55

Abstract: A method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of Pseudolysimachion rotundum var subintegrum than that prepared by the conventional preparation method disclosed in the prior art and the therapeutics or functional health food comprising the purified extract for treating and preventing inflammatory, allergic or asthmatic disease. The purified extract showed more potent anti-inflammatory, anti-allergy and anti-asthma activity than that prepared by the conventional preparation method disclosed in the prior art through various in vivo tests such as inhibition test on the reproduction of eosinophil, the release of immunoglobulin and inflammatory chemokines in plasma and bronchoalveolar fluid as well as the suppression of airway hyperresponsiveness and goblet cell hyperplasia in a OVA-sensitized/challenged mouse model.

Abstract translation: 一种制备纯化提取物的方法，该纯化提取物含有比现有技术中公开的常规制备方法制备的含有更丰富活性成分如萜类衍生物的提取物，其含有纯化的提取物，其用于治疗和/ 预防炎症，过敏性或哮喘性疾病。 纯化的提取物比通过各种体内试验例如现有技术公开的常规制备方法制备的抗炎，抗过敏和抗哮喘活性更强，如嗜酸性粒细胞的再生抑制试验，免疫球蛋白的释放 和血浆和支气管肺泡液中的炎性趋化因子以及在OVA致敏/攻击小鼠模型中抑制气道高反应性和杯状细胞增生。

公开(公告)号：US08679553B2

公开(公告)日：2014-03-25

申请号：US13727188

申请日：2012-12-26

Applicant: Aadvantics Pharmaceuticals, Inc.

Inventor： Brian M. Levine ,  William E. Berger

IPC: A61K36/53 ,  A61K36/736 ,  A61K36/80

CPC classification number: A61K36/53 ,  A61K36/185 ,  A61K36/324 ,  A61K36/736 ,  A61K36/80 ,  A61K2300/00

Abstract: An herbal composition for providing a beneficial effect to the respiratory tract. The composition includes Thyme Leaf, Wild Cherry Bark, Cocoa Extract, Mullein Leaf Extract, and Boswellia Serrata. In particular, the composition may prevent or treat cough, specifically caused by exposure to smoke. Also described are methods of using the herbal composition.

Abstract translation: 用于为呼吸道提供有益效果的草药组合物。 组合物包括百里香叶，野樱桃树皮，可可提取物，多毛叶提取物和乳香乳杆菌。 特别地，组合物可以预防或治疗咳嗽，特别是由暴露于烟雾引起的咳嗽。 还描述了使用草药组合物的方法。

公开(公告)号：US20080138446A1

公开(公告)日：2008-06-12

申请号：US11631218

申请日：2004-07-02

Applicant: Karina Anna Hilterman

Inventor： Karina Anna Hilterman

IPC: A61K36/00 ,  A61K36/15 ,  A61K36/23 ,  A61K36/268 ,  A61K36/328 ,  A61K36/38 ,  A61K36/50 ,  A61P17/00 ,  A61K36/54 ,  A61K36/66 ,  A61K36/71 ,  A61K36/80 ,  A61K36/86 ,  A61K36/886

CPC classification number: A61K36/28 ,  A61K36/13 ,  A61K36/185 ,  A61K36/48 ,  A61K36/66 ,  A61K36/86 ,  A61K2300/00

Abstract: The invention relates to a herbal composition comprising extracts from Thuja, Poke, Sweet violet, Red clover, Greater celandine and Calendula; formulations containing the herbal composition; and use of the herbal composition for preventing and/or treating skin conditions and/or abnormalities.

Abstract translation: 本发明涉及一种草药组合物，其中含有从Thuja，Poke，甜紫，红三叶草，大白ine和金盏花提取物; 含有草药组合物的制剂; 以及使用草药组合物来预防和/或治疗皮肤病症和/或异常。

公开(公告)号：US20070134193A1

公开(公告)日：2007-06-14

申请号：US11546588

申请日：2006-10-12

Applicant: Gilles Pauly ,  Philippe Moser ,  Louis Danoux ,  Olga Freis ,  Florence Henry ,  Muriel Pauly-Florentiny ,  Anne Guezennec ,  Joelle Guesnet

Inventor： Gilles Pauly ,  Philippe Moser ,  Louis Danoux ,  Olga Freis ,  Florence Henry ,  Muriel Pauly-Florentiny ,  Anne Guezennec ,  Joelle Guesnet

IPC: A61K8/97 ,  A61K36/899 ,  A61K36/80

CPC classification number: A61K8/645 ,  A61K8/60 ,  A61K8/602 ,  A61K8/73 ,  A61K8/97 ,  A61K36/00 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q19/004 ,  A61Q19/007 ,  A61Q19/08 ,  A61K2300/00

Abstract: A cosmetic or pharmaceutical composition containing an extract of a resurrection plant.

Abstract translation: 含有复活植物提取物的化妆品或药物组合物。