公开(公告)号：US11918620B2

公开(公告)日：2024-03-05

申请号：US17802380

申请日：2021-01-20

Applicant: Suzhou Regen-PharmaTech Co., Ltd.

Inventor： Be Xie ,  Xuefeng Ren

IPC: A61K36/9068 ,  A61K35/618 ,  A61K35/62 ,  A61K36/062 ,  A61K36/233 ,  A61K36/284 ,  A61K36/344 ,  A61K36/484 ,  A61K36/54 ,  A61K36/65 ,  A61K36/69 ,  A61K36/752 ,  A61K36/8888 ,  A61K36/899 ,  A61P3/06 ,  A61P9/10

CPC classification number: A61K36/9068 ,  A61K35/618 ,  A61K35/62 ,  A61K36/062 ,  A61K36/233 ,  A61K36/284 ,  A61K36/344 ,  A61K36/484 ,  A61K36/54 ,  A61K36/65 ,  A61K36/69 ,  A61K36/752 ,  A61K36/8888 ,  A61K36/899 ,  A61P3/06 ,  A61P9/10

Abstract: A traditional Chinese medicine composition, and preparation method, and application thereof. The traditional Chinese medicine composition includes the following raw medicines in parts by weight: 10-35 parts of root of Chinese thorowax, 5-25 parts of immature bitter orange, 3-20 parts of fresh root and rhizome of sorrel rhubarb, 3-20 parts of root of baikal skullcap, 3-20 parts of white peony root, 3-15 parts of dried ginger, 5-20 parts of leech, 3-20 parts of root of ural licorice, 3-20 parts of root pilose asiabell, 3-20 parts of rhizome of largehead atractylodes, and 3-25 parts of tuber of pinellia. The traditional Chinese medicine composition has excellent effects in lowering blood lipids and cholesterol levels, particularly in lowering blood triglyceride. The traditional Chinese medicine composition also has excellent effects in slowing formation of atherosclerotic plaques, clearing the atherosclerotic plaques, and preventing and treating atherosclerosis.

公开(公告)号：US09951148B2

公开(公告)日：2018-04-24

申请号：US14114461

申请日：2012-04-27

Applicant: Jari Helin ,  Jean Hypolites Koek

Inventor： Jari Helin ,  Jean Hypolites Koek

IPC: A61K36/24 ,  C08B37/00 ,  A61K31/732 ,  A61K36/748 ,  A61K36/896 ,  A61K36/8966 ,  A61K36/074 ,  A61K36/344 ,  A61K36/41 ,  A61K36/481 ,  A61K36/539 ,  A23L33/105

CPC classification number: C08B37/006 ,  A23L33/105 ,  A61K31/732 ,  A61K36/074 ,  A61K36/24 ,  A61K36/344 ,  A61K36/41 ,  A61K36/481 ,  A61K36/539 ,  A61K36/748 ,  A61K36/896 ,  A61K36/8966 ,  C08B37/0045 ,  C08B37/0048 ,  A61K2300/00

Abstract: The invention relates to a method for production of a preparation from a vegetable material, said preparation being enriched in a polysaccharide with a backbone comprising rhamnogalacturonan-I cores, said methodcomprising the steps: mixing the vegetable material with a polar alcoholic solvent; and separating a solid residue obtained in step a) from the solvent; and mixing the solid residue obtained in step b) with a buffered aqueous solution having a pH between 7 and 8. Also provided is a preparation containing rhamnogalacturonan-I pectins that can be obtained by this method and the use of such a preparation to modulate immune response.

公开(公告)号：US20180028591A1

公开(公告)日：2018-02-01

申请号：US15224991

申请日：2016-08-01

Applicant: Shaobin Ke

Inventor： Shaobin Ke

IPC: A61K36/9066 ,  A61K36/537 ,  A61K36/752 ,  A61K36/70 ,  A61K36/296 ,  A61K36/185 ,  A61K36/73 ,  A61K36/481 ,  A61K36/8945 ,  A61K36/65 ,  A61K36/28 ,  A61K36/605 ,  A61K36/39 ,  A61K36/344

CPC classification number: A61K36/9066 ,  A61K36/185 ,  A61K36/28 ,  A61K36/296 ,  A61K36/344 ,  A61K36/39 ,  A61K36/481 ,  A61K36/537 ,  A61K36/605 ,  A61K36/65 ,  A61K36/70 ,  A61K36/73 ,  A61K36/752 ,  A61K36/8945 ,  A61K2236/00 ,  A61K2300/00

Abstract: An herbal composition that enhances and promotes fertility in both males and females by nourishing the kidney, regulating the liver and spleen, improving circulation of Qi and blood, and balancing the Yin and Yang through a unique composition consisting of natural herbs known in traditional Chinese medicine. The herbs create a synergy between each other that works to enhance fertility for both males and females. The composition consists of the following herbal ingredients mixed in varying weight percentages. goji berry, dodder seed, red sage root, green orange peel, processed fleece flower root, horny goat weed, codonopsis, raspberry, astragalus root, Chinese yam, white peony root, false daisy, mulberry, curcuma tuber, and cynomorium. The herbal ingredients are cleaned, purified and/or processed prior to formulation. The formulation process is at least partially dependent on the desired means of preparation and administering the composition.

公开(公告)号：US09861671B2

公开(公告)日：2018-01-09

申请号：US14403990

申请日：2013-05-27

Applicant: JIANGZHONG PHARMACEUTICAL CO., LTD.

Inventor： Hongguang Zhong ,  Minzhi Yi ,  Jianzhong Lu

IPC: A61K36/00 ,  A61K36/481 ,  A61K36/068 ,  A61K36/074 ,  A61K36/258 ,  A61K36/344 ,  A61K36/36 ,  A61K36/73 ,  A61K9/08 ,  A61K9/00 ,  A61K9/14 ,  A61K9/16 ,  A61K9/20 ,  A61K9/48

CPC classification number: A61K36/481 ,  A61K9/0056 ,  A61K9/0095 ,  A61K9/08 ,  A61K9/141 ,  A61K9/1605 ,  A61K9/2004 ,  A61K9/4841 ,  A61K36/068 ,  A61K36/074 ,  A61K36/258 ,  A61K36/344 ,  A61K36/36 ,  A61K36/73 ,  A61K2300/00

Abstract: The present invention relates to a pharmaceutical composition made from the following raw materials or from water and/or alcohol extracts of the following raw materials in parts by weight: 5 to 200 parts of Ganoderma, 5 to 150 parts of Radix Panacis Quinquefolii or Radix Et Rhizoma Ginseng, 1 to 90 parts of fermented Cordyceps sinensis powder and/or 1 to 120 parts of Cordyceps, and optionally one or more of 5 to 90 parts of Flos Rosae Rugosae, 5 to 150 parts of Ganoderma spore powder, 10 to 400 parts of Radix Pseudostellariae, 3 to 400 parts of Radix Codonopsis and 3 to 400 parts of Radix Astragali. Clinical trials demonstrate that the composition can significantly reduce HIV virus load in patients, increase the number of CD4+ cells, enhance the immunity of patients, has no considerable toxic and side effects, and is suitable for long-term use.

公开(公告)号：US09744203B2

公开(公告)日：2017-08-29

申请号：US14403978

申请日：2013-05-27

Applicant: JIANGZHONG PHARMACEUTICAL CO., LTD.

Inventor： Hongguang Zhong ,  Minzhi Yi ,  Jianzhong Lu

IPC: A61K36/00 ,  A61K36/738 ,  A61K36/068 ,  A61K36/074 ,  A61K36/258 ,  A61K36/344 ,  A61K36/36 ,  A61K36/481 ,  A61K36/73 ,  A61K36/062 ,  A61K9/00 ,  A61K9/20 ,  A61K9/08 ,  A61K9/14 ,  A61K9/16 ,  A61K9/48

CPC classification number: A61K36/738 ,  A61K9/0056 ,  A61K9/0095 ,  A61K9/08 ,  A61K9/141 ,  A61K9/1605 ,  A61K9/2004 ,  A61K9/4841 ,  A61K36/062 ,  A61K36/068 ,  A61K36/074 ,  A61K36/258 ,  A61K36/344 ,  A61K36/36 ,  A61K36/481 ,  A61K36/73 ,  A61K2300/00

Abstract: The present invention relates to use of a composition in the manufacture of a health care product or medicament for preventing and treating leucopenia induced by radiotherapy or chemotherapy. The composition is made from raw materials comprising 5 to 200 parts by weight of Ganoderma, 5 to 150 parts by weight of Radix Panacis Quinquefolii or Radix Et Rhizoma Ginseng, 1 to 90 parts by weight of fermented Cordyceps sinensis powder and/or 1 to 120 parts by weight of Cordyceps, or is a composition consisting of water and/or alcohol extracts of the above raw materials as active components.

公开(公告)号：US09724416B2

公开(公告)日：2017-08-08

申请号：US14401773

申请日：2013-05-08

Applicant: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Darren Williams ,  Da-Woon Jung ,  Soon-Ho Yim

IPC: A61K38/06 ,  A61K41/00 ,  A61K36/344 ,  A61K36/539 ,  A61K36/71 ,  A61K47/48 ,  A61K8/41 ,  A61K8/64 ,  A61Q7/00

CPC classification number: A61K41/0061 ,  A61K8/41 ,  A61K8/64 ,  A61K36/344 ,  A61K36/539 ,  A61K36/71 ,  A61K38/06 ,  A61K47/542 ,  A61K47/64 ,  A61K2800/57 ,  A61K2800/81 ,  A61Q7/00 ,  A61K2300/00

Abstract: The present invention relates to a composition for improving or promoting hair growth, which contains, as an active ingredient, a photosensitizer-peptide conjugate, and to a method for screening for the hair growth promoter using the active ingredients. ALA, which is the photosensitizer of the present invention, is preferably activated by LED radiation, and more preferably activated by radiation having a long wavelength of 650 to 675 nm. The peptide of the present invention is a peptide in which 3 to 7 amino acid residues are incorporated (most preferably, glycine-histidine-lysine), and may cooperate with the photosensitizer to enable very superior hair growth improving or promoting effects using light radiation. Further, the composition of the present invention may exhibit further superior effects when natural extracts (for example, Cimicifuga heracleifolia extracts, Scutellaria baicalensis extracts or Codonopsis lanceolata extracts) are added. Thus, the composition of the present invention can be significantly advantageously applied to drugs, quasi-drugs, and cosmetics.

公开(公告)号：US20150290275A1

公开(公告)日：2015-10-15

申请号：US14403978

申请日：2013-05-27

Applicant: JIANGZHONG PHARMACEUTICAL CO., LTD.

Inventor： Hongguang Zhong ,  Minzhi Yi ,  Jianzhong Lu

IPC: A61K36/738 ,  A61K36/36 ,  A61K36/062 ,  A61K36/074 ,  A61K36/258

CPC classification number: A61K36/738 ,  A61K9/0056 ,  A61K9/0095 ,  A61K9/08 ,  A61K9/141 ,  A61K9/1605 ,  A61K9/2004 ,  A61K9/4841 ,  A61K36/062 ,  A61K36/068 ,  A61K36/074 ,  A61K36/258 ,  A61K36/344 ,  A61K36/36 ,  A61K36/481 ,  A61K36/73 ,  A61K2300/00

Abstract: The present invention relates to use of a composition in the manufacture of a health care product or medicament for preventing and treating leucopenia induced by radiotherapy or chemotherapy. The composition is made from raw materials comprising 5 to 200 parts by weight of Ganoderma, 5 to 150 parts by weight of Radix Panacis Quinquefolii or Radix Et Rhizoma Ginseng, 1 to 90 parts by weight of fermented Cordyceps sinensis powder and/or 1 to 120 parts by weight of Cordyceps, or is a composition consisting of water and/or alcohol extracts of the above raw materials as active components.

Abstract translation: 本发明涉及组合物在制备用于预防和治疗由放射治疗或化学疗法诱导的白细胞减少症的保健产品或药物中的用途。 该组合物由包含5至200重量份灵芝的原料制成，5至150重量份的甘草或人参，1至90重量份的发酵冬虫夏草粉和/或1至120 重量的冬虫夏草，或者是由上述原料的水和/或醇提取物作为活性成分组成的组合物。

公开(公告)号：US20150231163A1

公开(公告)日：2015-08-20

申请号：US14421770

申请日：2013-08-14

Applicant: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY

Inventor： Dong-Hyun Kim ,  Myung Joo Han ,  Se Eun Jang

IPC: A61K31/7048 ,  A61K31/7032 ,  A61K31/4745 ,  A61K31/704 ,  A61K36/344 ,  A61K36/718 ,  A61K36/88 ,  A61K35/64

CPC classification number: A61K31/7048 ,  A23L33/105 ,  A61K9/08 ,  A61K9/19 ,  A61K31/4745 ,  A61K31/7032 ,  A61K31/704 ,  A61K35/63 ,  A61K35/64 ,  A61K36/22 ,  A61K36/344 ,  A61K36/718 ,  A61K36/88 ,  A61K36/8964 ,  A61K2300/00

Abstract: The present invention relates to a novel use of an Anemarrhena asphodeloides Bunge extract and the like, and provides a composition for preventing or treating colitis, including an Anemarrhena asphodeloides Bunge extract, a fraction thereof or a compound isolated therefrom as an active ingredient. In addition, the present invention relates to a novel use of a combined extract of medicinal herbs, and provides a composition for preventing or treating colitis, including an Anemarrhena asphodeloides Bunge extract, a Galla Rhois extract, a Codonopsis lancellata extract, and the like as active ingredients, or including an Anemarrhena asphodeloides Bunge extract, a Coptis japonica Makino extract, and the like as active ingredients. According to the present invention, the Anemarrhena asphodeloides Bunge extract and the like or the combined extract can be used as a food or medical materials constituting a pharmaceutical composition or a nutraceutical composition. The pharmaceutical composition or the nutraceutical composition can be used for preventing or treating acute colitis or chronic colitis, and particularly, can effectively prevent, delay, alleviate or treat inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and the like.

Abstract translation: 本发明涉及一种Anemarrhena asphodeloides Bunge提取物的新用途，并提供一种预防或治疗结肠炎的组合物，包括Anemarrhena asphodeloides Bunge提取物，其分数或其分离的化合物作为活性成分。 此外，本发明涉及药草组合提取物的新用途，提供了预防或治疗结肠炎的组合物，包括Anemarrhena asphodeloides Bunge提取物，Galla Rhois提取物，Codonopsis lancellata提取物等作为 活性成分，或者包括Anemarrhena asphodeloides Bunge提取物，黄连提取物等作为有效成分。 根据本发明，可以将Anemarrhena asphodeloides Bunge提取物等或组合的提取物用作构成药物组合物或营养药物组合物的食品或医疗材料。 药物组合物或营养药物组合物可用于预防或治疗急性结肠炎或慢性结肠炎，特别是可有效预防，延缓，缓解或治疗炎性肠病（IBD），肠易激综合征（IBS）等。

公开(公告)号：US20150079128A1

公开(公告)日：2015-03-19

申请号：US14029963

申请日：2013-09-18

Applicant: Hong Kong Baptist University

Inventor： Zhaoxiang Bian ,  Siu Wai Tsang ,  Siu Po Ip ,  Che Yuen Justin Wu ,  Aiping Lu ,  Albert Sun Chi Chan

IPC: A61K36/9068 ,  A61K36/718 ,  A61K36/076 ,  A61K36/71 ,  A61K36/344 ,  A61K36/284

CPC classification number: A61K36/9068 ,  A61K36/076 ,  A61K36/284 ,  A61K36/344 ,  A61K36/65 ,  A61K36/71 ,  A61K36/718 ,  A61K2300/00

Abstract: This invention relates to a Chinese medicinal formulation for the treatment of inflammatory bowel diseases, and a method of preparation thereof. The formulation comprises herbal components selected from a group consisting of Radix Codonopsis (Dangshen), Rhizoma Atractylodis Macrocephalae (Bai Zhu), Sclerotium Poriae Cocos (Fu Ling), Rhizoma Zingiberis Officinalis (Gan Jiang), Radix Paeoniae Alba (Bai Shao) and Rhizoma Coptidis (Huanglian).

Abstract translation: 本发明涉及一种治疗炎性肠病的中药制剂及其制备方法。 该制剂包含选自由党参（Dangshen），白术（白芍），茯苓（Fu Ling），an姜（Gan Jiang），白芍（Bai Shao），白芍（Rhizoma） 黄连（黄连）。

公开(公告)号：US08628806B2

公开(公告)日：2014-01-14

申请号：US12441899

申请日：2007-09-26

Applicant: Like Tang ,  Dianwu Guo ,  Chunxia Wu ,  Kai Tang ,  Tianjia Xu

Inventor： Like Tang ,  Dianwu Guo ,  Chunxia Wu ,  Kai Tang ,  Tianjia Xu

IPC: A61K36/00

CPC classification number: A61K36/344 ,  A61K36/65 ,  A61K2300/00

Abstract: The present invention provides a hypolipidemic composition comprising peony extract and Codonopsis extract, or comprising water coextract of peony and Codonopsis, the weight ratio of the peony extract to Codonopsis extract in the composition is between 0.5 and 19:1. The advantages of the hypolipidemic composition are: substantially decreasing triglyceride and cholesterol, while increasing high density lipoprotein. It suggested of a favourable prospect of application.

Abstract translation: 本发明提供了含有牡丹提取物和党参提取物的降血脂成分，或者包含牡丹和党参的水共提取物，组合物中牡丹提取物与党参提取物的重量比为0.5〜19:1。 降血脂组合物的优点是：大大降低甘油三酯和胆固醇，同时增加高密度脂蛋白。 提出有利的应用前景。