公开(公告)号：US20150231163A1

公开(公告)日：2015-08-20

申请号：US14421770

申请日：2013-08-14

Applicant: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY

Inventor： Dong-Hyun Kim ,  Myung Joo Han ,  Se Eun Jang

IPC: A61K31/7048 ,  A61K31/7032 ,  A61K31/4745 ,  A61K31/704 ,  A61K36/344 ,  A61K36/718 ,  A61K36/88 ,  A61K35/64

CPC classification number: A61K31/7048 ,  A23L33/105 ,  A61K9/08 ,  A61K9/19 ,  A61K31/4745 ,  A61K31/7032 ,  A61K31/704 ,  A61K35/63 ,  A61K35/64 ,  A61K36/22 ,  A61K36/344 ,  A61K36/718 ,  A61K36/88 ,  A61K36/8964 ,  A61K2300/00

Abstract: The present invention relates to a novel use of an Anemarrhena asphodeloides Bunge extract and the like, and provides a composition for preventing or treating colitis, including an Anemarrhena asphodeloides Bunge extract, a fraction thereof or a compound isolated therefrom as an active ingredient. In addition, the present invention relates to a novel use of a combined extract of medicinal herbs, and provides a composition for preventing or treating colitis, including an Anemarrhena asphodeloides Bunge extract, a Galla Rhois extract, a Codonopsis lancellata extract, and the like as active ingredients, or including an Anemarrhena asphodeloides Bunge extract, a Coptis japonica Makino extract, and the like as active ingredients. According to the present invention, the Anemarrhena asphodeloides Bunge extract and the like or the combined extract can be used as a food or medical materials constituting a pharmaceutical composition or a nutraceutical composition. The pharmaceutical composition or the nutraceutical composition can be used for preventing or treating acute colitis or chronic colitis, and particularly, can effectively prevent, delay, alleviate or treat inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and the like.

Abstract translation: 本发明涉及一种Anemarrhena asphodeloides Bunge提取物的新用途，并提供一种预防或治疗结肠炎的组合物，包括Anemarrhena asphodeloides Bunge提取物，其分数或其分离的化合物作为活性成分。 此外，本发明涉及药草组合提取物的新用途，提供了预防或治疗结肠炎的组合物，包括Anemarrhena asphodeloides Bunge提取物，Galla Rhois提取物，Codonopsis lancellata提取物等作为 活性成分，或者包括Anemarrhena asphodeloides Bunge提取物，黄连提取物等作为有效成分。 根据本发明，可以将Anemarrhena asphodeloides Bunge提取物等或组合的提取物用作构成药物组合物或营养药物组合物的食品或医疗材料。 药物组合物或营养药物组合物可用于预防或治疗急性结肠炎或慢性结肠炎，特别是可有效预防，延缓，缓解或治疗炎性肠病（IBD），肠易激综合征（IBS）等。