Glycosylated indolocarbazole synthesis
    7.
    发明授权
    Glycosylated indolocarbazole synthesis 失效
    糖基化吲哚并咔唑合成

    公开(公告)号:US07038043B1

    公开(公告)日:2006-05-02

    申请号:US09482235

    申请日:2000-01-13

    IPC分类号: C07D273/00

    CPC分类号: C07D498/22 C07C45/68

    摘要: Indolocarbazoles are furanosylated (e.g., 7) with acetals (e.g., 8) or their open chain congeners (e.g., 9) under conditions known to promote acetal exchange or formation, such as protic or Lewis acids. Furanosylated indolocarbazoles (e.g., 10) are also prepared via ring contraction of pyranosylated indolocarbazoles (e.g., 11) under conditions know to effect oxidation and benzylic acid type rearrangements, and pyranosylated indolocarbazoles (e.g., 11) are prepared via ring expansion of the furanosylated congeners (e.g., 10)

    摘要翻译: 在已知可促进乙缩醛交换或形成的条件下,例如质子酸或路易斯酸,吲哚并吡唑类化合物(例如7)具有缩醛(例如8)或其开链同系物(例如9)。 呋喃糖基化吲哚并唑(例如,10)也是通过吡喃糖基化吲哚并唑(例如11)在已知有效氧化和苄酸型重排的条件下通过环收缩来制备的,吡喃糖基化的吲哚并唑(例如,11)是通过呋喃糖基化同系物 (例如10)