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    ROOM AIR CLEANSING USING HYDROPONIC PLANTS
    1.
    发明申请
    ROOM AIR CLEANSING USING HYDROPONIC PLANTS 有权
    室内空气清洁使用水电植物

    公开(公告)号：US20030224507A1

    公开(公告)日：2003-12-04

    申请号：US10157912

    申请日：2002-05-31

    发明人： Alan Blake Darlington

    IPC分类号： C12M001/14

    CPC分类号： F24F3/16 ,  A01G31/00 ,  B01D53/85 ,  B01D2257/708 ,  F24F2003/1653 ,  F24F2006/005 ,  Y02A50/2359

    摘要： The plants are disposed on a near-vertical matrix panel of porous or fibrous inert material, in which the roots of the plants are embedded. Hydroponic water trickles down the panel, keeping the roots wet. A fan draws the air to be treated horizontally through the panel. The unit freshens stale air in a room. It may be provided as a wall-mounted unit, or as a self-standing tower unit.

    摘要翻译： 将植物放置在多孔或纤维惰性材料的近垂直矩阵板上，植物的根部嵌入其中。 水培水浸在面板上，保持根部湿润。 风扇将空气通过面板水平地对待。 该单位更新室内陈旧的空气。 它可以被设置为壁挂式单元，或者作为自立塔单元。

    Method for inducing immunosuppressive cells and a culture device to be used therefor
    3.
    发明申请
    Method for inducing immunosuppressive cells and a culture device to be used therefor 审中-公开
    诱导免疫抑制细胞的方法和用于其的培养装置

    公开(公告)号：US20010024822A1

    公开(公告)日：2001-09-27

    申请号：US09756214

    申请日：2001-01-09

    发明人： Kenji Yamashita ,  Takeshi Fukuchi ,  Tomoko Nishino

    IPC分类号： C12N005/06 ,  C12N005/08 ,  C12M001/14 ,  C12M003/04

    CPC分类号： C12N5/0636 ,  A61K2035/122 ,  C12M25/00 ,  C12N2501/23 ,  C12N2501/515 ,  C12N2501/599

    摘要： The present invention provides a method for inducing immunosuppressive cells by cultivating human cells with the use of a culture device having an affinity for protein and the culture device to be used therefor. According to the present invention, immunosuppressive cells can be efficiently induced by using a solid culture and can provide an efficient therapeutic system for diseases caused by hypersensitivity of the immune system with less side effect.

    摘要翻译： 本发明提供通过使用对蛋白质具有亲和力的培养装置和用于其的培养装置培养人细胞来诱导免疫抑制细胞的方法。 根据本发明，可以通过使用固体培养物有效地诱导免疫抑制细胞，并且可以为免疫系统的超敏反应引起的疾病提供有效的治疗系统，而副作用较小。

    Novel porous vessel bioreactor
    4.
    发明申请
    Novel porous vessel bioreactor 失效
    新型多孔容器生物反应器

    公开(公告)号：US20040110280A1

    公开(公告)日：2004-06-10

    申请号：US10310495

    申请日：2002-12-05

    发明人： Nitin Wasantrao Fadnavis ,  Bankupalli Satyavathi ,  Gurrala Sheelu ,  Vasantha Madhuri Kallakunta ,  Trishool Namani

    IPC分类号： C12M001/34 ,  C12M001/14

    CPC分类号： C12M21/18 ,  C12M23/02 ,  C12M23/20 ,  C12M23/34 ,  C12M25/18 ,  C12M29/02 ,  C12M33/14 ,  C12M33/22 ,  C12M41/22 ,  Y10S435/813

    摘要： The present invention provides a porous vessel bioreactor apparatus for use in reaction with immobilized enzymes and/or microbial cells, said apparatus consisting of a vertically elongated reaction vessel having at least one liquid reactant inlet; at least one product outlet on the vessel; at least one porous vessel completely submerged in the reactant, said porous vessel having pore size ranging from 5 mm to 0.2 microns and a vertical length less than a level of the reactants to be maintained in the vessel, and immobilized bio-catalyst particles comprising the enzymes and/or microbial cells placed inside the porous vessel such that the liquid reactant is in contact with the bio-catalyst in both radial and axial directions.

    摘要翻译： 本发明提供一种用于与固定化酶和/或微生物细胞反应的多孔容器生物反应器装置，所述装置由具有至少一种液体反应物入口的垂直伸长的反应容器组成; 船上至少有一个产品出口; 至少一个多孔容器完全浸没在反应物中，所述多孔容器的孔径范围为5mm至0.2微米，垂直长度小于待保持在容器中的反应物的水平，以及固定的生物催化剂颗粒，其包含 酶和/或微生物细胞放置在多孔容器内，使得液体反应物在径向和轴向上与生物催化剂接触。

    Method and apparatus for multi-layer growth of anchorage dependent cells
    5.
    发明申请
    Method and apparatus for multi-layer growth of anchorage dependent cells 审中-公开
    锚固依赖细胞多层生长的方法和装置

    公开(公告)号：US20040023374A1

    公开(公告)日：2004-02-05

    申请号：US10416561

    申请日：2003-05-12

    发明人： Catherine Rappaport ,  Edward Trujillo ,  Yvonne Rensch ,  Masoud Abbasi ,  Michael Kempe ,  Christian Rocaboy ,  John Gladysz

    IPC分类号： C12N005/06 ,  C12M001/14 ,  C12M003/04

    CPC分类号： C12N5/0068 ,  C12M23/08 ,  C12M23/20 ,  C12M23/24 ,  C12M23/38 ,  C12M23/48 ,  C12M29/04 ,  C12N2533/50

    摘要： Anchorage-dependent cells are grown in a novel cell culture plate and on a novel substratum which increase the oxygenation of the cells. The cell culture plate is made by enclosing a growth chamber within a shell made of a solid sterilizable. One or more culture wells are positioned within the chamber. An inlet port and outlet port are fashioned within the shell for gas exchange. The wells have a well wall which allows for the diffusion of oxygen from the chamber into the well. A perfluorocarbon is placed within the well. A perfluoro-aldehyde is mixed with the perfluorocarbon, and the perfluoro-aldehyde re-orients so that the aldehyde head groups are at the interface. An attachment factor is bound to the perfluoro-aldehyde, which is sunk into the PFC substratum. Aqueous growth media is then added to the well, and anchorage-dependent cells added and allowed to grow.

    摘要翻译： 锚定依赖性细胞在新型细胞培养板和增加细胞氧合作用的新颖基质上生长。 细胞培养板通过将生长室包封在由固体灭菌的壳体内制成。 一个或多个培养孔位于室内。 入口端口和出口端口形成在壳体内用于气体交换。 井具有井壁，其允许氧从室扩散到井中。 将全氟化碳置于该孔内。 全氟醛与全氟化碳混合，全氟醛重新定向，使醛头基团在界面处。 附着因子与全氟醛结合，其被沉积到PFC底物中。 然后将水生长培养基加入到孔中，并且添加锚定依赖细胞并允许其生长。

    Bio-reactor device
    6.
    发明申请
    Bio-reactor device 失效
    生物反应器装置

    公开(公告)号：US20030180942A1

    公开(公告)日：2003-09-25

    申请号：US10380482

    申请日：2003-03-12

    发明人： Schalk Van Der Merwe ,  Francis Sean Moolman ,  Robert Paul Bond ,  Adriaan Jacobus Van Wyk

    IPC分类号： C12M001/14 ,  C12M003/04

    CPC分类号： C12M25/14 ,  C12M23/20 ,  C12M29/10 ,  C12M41/22

    摘要： The invention provides a bio-reactor device and a method of cultivating live cells. The device comprises a holder which contains a matrix of porous foam material in whose interior live cells are anchored, the device comprising also a liquid contained in the holder. The liquid is an oxygen carrier and satarates the matrix, the liquid comprising a synthetic or semi-synthetic constituent. The method involves perfusing the oxygen carrier liquid through the matrix to deliver oxygen to the cells and to absorb carbo-dioxide from the cells.

    摘要翻译： 本发明提供一种生物反应器装置和培养活细胞的方法。 该装置包括一个保持器，该支架包含多孔泡沫材料的基体，其内部的活细胞被锚定，该装置还包括容纳在支架中的液体。 液体是氧载体并使基质饱和，液体包含合成或半合成成分。 该方法包括通过基质灌注氧载体液体以将氧气输送到细胞并从细胞吸收二氧化碳。

    Fabrication of vascularized tissue using microfabricated two-dimensional molds
    7.
    发明申请
    Fabrication of vascularized tissue using microfabricated two-dimensional molds 审中-公开
    使用微细二维模具制造血管化组织

    公开(公告)号：US20030003575A1

    公开(公告)日：2003-01-02

    申请号：US10200955

    申请日：2002-07-22

    发明人： Joseph P. Vacanti ,  Jeffrey T. Borenstein ,  Homer Pien ,  Brian T. Cunningham

    IPC分类号： C12N005/08 ,  C12M001/14 ,  C12M003/04

    CPC分类号： A61L27/3604 ,  A61K35/12 ,  A61K35/44 ,  A61L27/38 ,  B33Y70/00 ,  C12N5/0671 ,  C12N5/0697 ,  C12N2502/14 ,  C12N2502/28 ,  C12N2535/10

    摘要： A method and materials to create complex vascularized living tissue in three dimensions from a two-dimension microfabricated mold has been developed. The method involved creating a two dimensional surface having a branching structure etched into the surface. The pattern begins with one or more large channels which serially branch into a large array of channels as small as individual capillaries, then converge to one or more large channels. The etched surface serves a template within a mold formed with the etched surface for the circulation of an individual tissue or organ. Living vascular cells are then seeded onto the mold, where they form living vascular channels based on the pattern etched in the mold. Once formed and sustained by their own matrix, the top of the mold is removed. The organ or tissue specific cells are then added to the etched surface, where they attach and proliferate to form a thin, vascularized sheet of tissue. The tissue can then be gently lifted from the mold using techniques such as fluid flow and other supporting material, as necessary. The tissue can then be systematically folded and compacted into a three-dimensional vascularized structure. This structure can then be implanted into animals or paitents by directly connecting the blood vessels to flow into and out of the device. Immediate perfusion of oxygenated blood occurs, which allows survival and function of the entire living mass.

    摘要翻译： 已经开发了从二维微加工模具在三维中产生复杂血管化活组织的方法和材料。 该方法涉及创建具有蚀刻到表面中的分支结构的二维表面。 该模式从一个或多个大的通道开始，该通道串行地分支成与单个毛细管一样小的通道的大阵列，然后收敛到一个或多个大通道。 被蚀刻的表面在形成有蚀刻表面的模具内形成模板，用于各个组织或器官的循环。 然后将活的血管细胞接种到模具上，基于在模具中蚀刻的图案形成活血管通道。 一旦通过自己的矩阵形成并维持，模具的顶部被移除。 然后将器官或组织特异性细胞加入到蚀刻的表面中，在那里它们附着和增殖以形成薄的，血管化的组织片。 然后可以根据需要使用诸如流体流动和其它支撑材料的技术从模具中轻轻地提起组织。 然后可以将组织系统地折叠并压实成三维血管结构。 然后可以通过直接连接血管流入和流出装置将该结构植入动物或药物中。 发生氧合血液的立即灌注，这允许整个生物体的存活和功能。

    Biological filter for the purification of waste gases
    9.
    发明申请
    Biological filter for the purification of waste gases 有权
    用于净化废气的生物过滤器

    公开(公告)号：US20030082794A1

    公开(公告)日：2003-05-01

    申请号：US09983224

    申请日：2001-10-23

    发明人： Ajit Haridas ,  Swachchha Majumdar

    IPC分类号： B01D053/85 ,  C12M001/14

    CPC分类号： B01D53/84 ,  B01D53/85 ,  Y02A50/2358 ,  Y02A50/2359

    摘要： The present invention relates to a biological filter for the purification of waste gases comprising a bed of biologically active carrier material consisting of pith extracted from coconut husks, the bed being contained such that the waste gases are brought in contact with the said bed and removed from the bed at points spatially separated from the inlet points.

    摘要翻译： 本发明涉及一种用于净化废气的生物过滤器，包括由椰子壳提取的由树脂提取的生物活性载体材料床，所述床被包含以使废气与所述床接触并从 在与入口点空间分离的点处的床。

    BIOLOGICAL FILTER STRUCTURES
    10.
    发明申请
    BIOLOGICAL FILTER STRUCTURES 有权
    生物滤池结构

    公开(公告)号：US20030040108A1

    公开(公告)日：2003-02-27

    申请号：US09938466

    申请日：2001-08-23

    发明人： Baron V. Adams ,  Paul C. John ,  Charles S. Swift

    IPC分类号： C12M001/14

    CPC分类号： B01D53/85 ,  Y02A50/2359

    摘要： A biological filter element includes a support element of generally ellipsoidal configuration. The support element has two opposite polar regions and includes a medial ring intermediate the two opposite polar regions and a plurality of arcuate ribs extending from the medial ring to each polar region. Adjacent arcuate ribs are angularly spaced to provide access to an interior space of the support element. A cohesive body of biologically active material surrounds the support element and penetrates the interior space of the support element.

    摘要翻译： 生物过滤元件包括通常椭圆形构造的支撑元件。 支撑元件具有两个相对的极性区域，并且包括在两个相对极性区域中间的中间环和从内侧环延伸到每个极性区域的多个弧形肋。 相邻的弓形肋是有角度地间隔开的，以提供到支撑元件的内部空间的通路。 生物活性物质的内聚体围绕支撑元件并穿透支撑元件的内部空间。