公开(公告)号：US10335430B2

公开(公告)日：2019-07-02

申请号：US12822749

申请日：2010-06-24

Applicant: Anne Frippiat ,  Jan Van Loo ,  Georges Smits

Inventor： Anne Frippiat ,  Jan Van Loo ,  Georges Smits

IPC: A61K31/733 ,  C08B37/18 ,  A23L29/244

Abstract: Inulin products which consist of a particular mixture of an easily fermentable inulin (EFI) component and a hardly fermentable inulin (HFI) component are provided. The products have advantageous nutritional effects/benefits which include dietary fiber effects, improved mineral absorption, particularly calcium and magnesium, bone mineral density increase, reduction of bone mineral density loss, modulation of lipid metabolism, stimulation of the immune system, and anti-cancer effects.

公开(公告)号：US09717801B2

公开(公告)日：2017-08-01

申请号：US14376299

申请日：2013-02-21

Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.

Inventor： Vincenzo Russo ,  Elisa Liberati ,  Nicola Cazzolla

IPC: A61K47/46 ,  A61K47/48 ,  C08B37/00 ,  A61K31/716 ,  A61K31/713 ,  C08B37/18

CPC classification number: A61K47/4823 ,  A61K31/713 ,  A61K31/716 ,  A61K47/61 ,  A61K2201/324 ,  A61K2201/326 ,  C08B37/0009 ,  C08B37/18

Abstract: The present invention relates to glycogen-based cationic polymers, to complexes of the said cationic polymers with anionic compounds, to pharmaceutical compositions comprising the said complexes, and to the use of the said complexes for delivering or transfecting the said anionic compounds to a specific pharmacological target, such as, for instance an organ, a tissue or a cell.

公开(公告)号：US09139718B2

公开(公告)日：2015-09-22

申请号：US14107067

申请日：2013-12-16

Applicant: E I DU PONT DE NEMOURS AND COMPANY

Inventor： Jayme L Paullin ,  Andrea M Perticone ,  Rahul B Kasat ,  T Joseph Dennes

IPC: C08B37/00 ,  C08B37/18 ,  C08L5/00 ,  C12P19/18 ,  C12P19/04

CPC classification number: C08B37/0009 ,  C08L5/00 ,  C12P19/04 ,  C12P19/18

Abstract: Poly alpha-1,3-glucan ether compounds are disclosed herein with a degree of substitution of about 0.05 to about 3.0. Also disclosed are methods of producing poly alpha-1,3-glucan ether compounds.

Abstract translation: 本文公开了聚α-1,3-葡聚糖醚化合物，其取代度为约0.05至约3.0。 还公开了生产聚α-1,3-葡聚糖醚化合物的方法。

公开(公告)号：US08778326B2

公开(公告)日：2014-07-15

申请号：US13379843

申请日：2010-06-30

Applicant: Helen S. M. Lu ,  Steven W. Shuey

Inventor： Helen S. M. Lu ,  Steven W. Shuey

IPC: A61L24/08 ,  C08B37/02 ,  C08B37/18 ,  C08B15/10 ,  C08B37/08 ,  C08B37/12 ,  C08B37/00 ,  C08B31/00 ,  A61L26/00

CPC classification number: A61L26/0052 ,  A61L24/0031 ,  A61L24/0042 ,  A61L24/043 ,  A61L24/046 ,  A61L24/08 ,  A61L26/0023 ,  A61L26/008 ,  A61L26/009 ,  C08L5/02 ,  C08L71/02 ,  C08L5/00

Abstract: A hydrogel tissue adhesive formed by reacting an aldehyde-functionalized polysaccharide containing pendant aldehyde groups with a water-dispersible, multi-arm amine is described. The hydrogel may be useful as a tissue adhesive or sealant for medical applications that require a more rapid degradation time, such as the prevention of undesired tissue-to tissue adhesions resulting from trauma or surgery.

公开(公告)号：US08580950B2

公开(公告)日：2013-11-12

申请号：US12973967

申请日：2010-12-21

Applicant: Helen S. M. Lu ,  Steven W. Shuey

Inventor： Helen S. M. Lu ,  Steven W. Shuey

IPC: C08B1/00 ,  C08L1/02 ,  C08L1/28 ,  C08L5/02 ,  C08L5/08 ,  C08L5/12 ,  C08B11/02 ,  C08B11/04 ,  C08B11/08 ,  C08B11/12 ,  C08B31/18 ,  C08B37/02 ,  C08B37/12 ,  C08B37/18

CPC classification number: C08B15/02 ,  C08B31/18 ,  C08B37/00 ,  C08B37/0018 ,  C08B37/0021 ,  C08B37/0054 ,  C08B37/0072 ,  C08L1/04 ,  C08L3/10 ,  C08L5/00 ,  C08L5/02 ,  C08L5/08 ,  C08L5/12

Abstract: Novel aldehyde-functionalized polysaccharide compositions containing pendant dialdehyde groups are described that are more stable in aqueous solution than oxidized polysaccharides. The aldehyde-functionalized polysaccharides may be reacted with various amine-containing polymers to form hydrogel tissue adhesives and sealants that may be useful for medical applications such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, preventing leakage of fluids such as blood, bile, gastrointestinal fluid and cerebrospinal fluid, ophthalmic procedures, drug delivery, and preventing post-surgical adhesions.

Abstract translation: 描述了含有侧链二醛基团的新型醛官能化多糖组合物，其在水溶液中比氧化多糖更稳定。 醛官能化多糖可以与各种含胺聚合物反应以形成可用于医学应用的水凝胶组织粘合剂和密封剂，例如伤口闭合，补充或替换缝合或缝合在内部外科手术如肠吻合和血管吻合中 ，组织修复，防止流体如血液，胆汁，胃肠道液体和脑脊液的渗漏，眼科手术，药物递送和预防手术后粘连。

公开(公告)号：US20120041188A1

公开(公告)日：2012-02-16

申请号：US13256420

申请日：2010-03-11

Applicant: Günther Laufenberg ,  Friedrich Meuser

Inventor： Günther Laufenberg ,  Friedrich Meuser

IPC: C08B37/18

CPC classification number: C08B37/0054

Abstract: The invention describes a method for obtaining inulin which comprises: a) finely comminuting inulin-containing plant material, wherein particle sizes of the plant material are generated which are smaller than the size of the inulin-containing plant cells, b) suspending the finely comminuted plant material in a liquid, wherein inulin is released from the plant material and suspended in particulate form in the liquid, c) separating off plant particles from the liquid, wherein the inulin which is suspended in particulate form remains in the liquid, d) separating off the inulin which is suspended in particulate form from the liquid. The method is suitable in particular for obtaining inulin from artichoke roots.

Abstract translation: 本发明描述了一种获得菊粉的方法，其包括：a）细粉碎的含菊粉的植物材料，其中产生的植物材料的粒径小于含菊粉的植物细胞的大小，b）将细粉碎的 液体中的植物材料，其中菊粉从植物材料中释放并以颗粒形式悬浮在液体中，c）从液体中分离出植物颗粒，其中以颗粒形式悬浮的菊粉保留在液体中，d）分离 从液体中以颗粒形式悬浮的菊粉。 该方法特别适用于从朝鲜蓟根获得菊粉。

公开(公告)号：US20070298485A1

公开(公告)日：2007-12-27

申请号：US10580279

申请日：2003-11-26

Applicant: Keiichi Takagaki ,  Satoshi Kaneko ,  Atsushi Kuno

Inventor： Keiichi Takagaki ,  Satoshi Kaneko ,  Atsushi Kuno

IPC: C08B37/18 ,  C12S3/02

CPC classification number: C12P19/26 ,  C12P19/64

Abstract: A method for collection of intact glycosaminoglycan from proteoglycan by cleaving a linkage region of core protein

Abstract translation: 通过切割核心蛋白的连锁区域，从蛋白聚糖中收集完整的糖胺聚糖的方法

公开(公告)号：US20050048142A1

公开(公告)日：2005-03-03

申请号：US10497694

申请日：2002-12-06

Applicant: Kazuyoshi Matsunaga ,  Takafumi Ishihara

Inventor： Kazuyoshi Matsunaga ,  Takafumi Ishihara

IPC: C08B37/00 ,  C08B37/18 ,  A61K31/715 ,  A61K35/78

CPC classification number: C08B37/0009

Abstract: A method of producing glycogen is provided. The method comprises the step of heat- and pressure-treating a sugar-containing material under acidic conditions. The sugar-containing material is a polysaccharide or an oligosaccharide. Alternatively, the sugar-containing material is a plant material selected from the group consisting of Panax notoginseng, Yun Nan San-chi powder (trademark), Panax ginseng, wheat flour, soybean, soy flour, shiitake, and coffee extract residue. Representatively, the glycogen includes a molecule having a molecular weight of 10,000 or less. The glycogen has a specific rotation of [α]D+197° and anomeric proton peaks at 5.37 ppm and 4.95 to 5.33 ppm in 1H NMR spectra.

Abstract translation: 提供了制备糖原的方法。 该方法包括在酸性条件下对含糖材料进行加热和加压处理的步骤。 含糖材料是多糖或寡糖。 或者，含糖材料是选自三七，云南三奇粉（商标），人参，小麦粉，大豆，大豆粉，香菇和咖啡提取物残渣的植物材料。 代表性地，糖原包括分子量为10,000以下的分子。 在1 H NMR光谱中，糖原具有αD+ 197°的比旋光度和5.37ppm和4.95-5.33ppm的异质质子峰。

公开(公告)号：US06844022B2

公开(公告)日：2005-01-18

申请号：US09782815

申请日：2001-02-14

Applicant: Rudolf Klingler ,  Karl-Georg Busch

Inventor： Rudolf Klingler ,  Karl-Georg Busch

IPC: A23L29/30 ,  C08B30/12 ,  C08B30/18 ,  C08B37/18 ,  A23L1/0522 ,  C08B31/00

CPC classification number: C08B30/18 ,  A23L29/35 ,  C08B30/12

Abstract: The present invention is in the technical field of physicochemical starch modification and relates to a process for producing thermochemically modified starch, the thin-boiling starches which are obtainable by the inventive process and thermally reversible gel-forming dextrins, and to their use, in particular as gelatin substitute or fat substitute.

Abstract translation: 本发明属于化学淀粉改性的技术领域，涉及生产热化学改性淀粉的方法，本发明方法可获得的薄沸腾淀粉和热可逆凝胶形成糊精，特别是它们的用途 作为明胶替代品或脂肪代用品。

公开(公告)号：US6146857A

公开(公告)日：2000-11-14

申请号：US43830

申请日：1998-06-15

Applicant: Gilles Pauly ,  Marc Pauly ,  Jean-Marc Engasser ,  Mohamed Ghoul

Inventor： Gilles Pauly ,  Marc Pauly ,  Jean-Marc Engasser ,  Mohamed Ghoul

IPC: A61K8/00 ,  A61K8/11 ,  A61K8/72 ,  A61K8/73 ,  A61K8/99 ,  A61Q17/04 ,  A61Q19/00 ,  C08B37/18 ,  C12N1/00 ,  C12N1/06 ,  C12N1/14 ,  C12P19/04 ,  C12R1/86 ,  A61K7/035 ,  C12P1/02

CPC classification number: A61K8/73 ,  A61Q19/00 ,  C12N1/063 ,  C12P19/04 ,  A61Q17/04 ,  Y10S435/911 ,  Y10S435/921 ,  Y10S435/94

Abstract: A process is provided for the production of glycogens or an extract rich in glycogens from yeast cells, and a cosmetic composition containing them. A given quantity of yeast cells, from a specific culture or recovered as residues of a fermentation process, is subjected to an operation of enrichment in intracellular glycogens by culturing in two phases in the presence of a carbon source. The metabolism of the yeast cells is then stopped. The membranes of the yeast cells are then at least partially disintegrated to free intracellular substances, and the freed intracellular substances are subjected to at least one precipation to precipitate glycogens. A cosmetic composition comprising the glycogens is formulated in admixture with a dermatologically acceptable excipient.

Abstract translation: PCT No.PCT / FR96 / 02008 Sec。 371日期1998年6月15日第 102（e）1998年6月15日PCT PCT 1996年12月13日PCT公布。 公开号WO97 / 21828 日期1996年6月19日提供了用于从酵母细胞中制备糖原或富含糖原的提取物的方法和含有它们的化妆品组合物的方法。 给定量的来自特定培养物的酵母细胞或作为发酵过程的残留物回收的酵母细胞通过在碳源的存在下在两相中培养来进行细胞内糖原的富集操作。 然后停止酵母细胞的代谢。 然后将酵母细胞的膜至少部分地分解成游离细胞内物质，并且释放的细胞内物质经历至少一个沉淀以沉淀糖原。 含有糖原的化妆品组合物与皮肤病学可接受的赋形剂混合配制。