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    Method for producing glycogens for use in cosmetics by culturing yeast cells in two phases
    3.
    发明授权
    Method for producing glycogens for use in cosmetics by culturing yeast cells in two phases 失效
    通过两相培养酵母细胞生产用于化妆品的糖原的方法

    公开(公告)号：US6146857A

    公开(公告)日：2000-11-14

    申请号：US43830

    申请日：1998-06-15

    Applicant: Gilles Pauly ,  Marc Pauly ,  Jean-Marc Engasser ,  Mohamed Ghoul

    Inventor： Gilles Pauly ,  Marc Pauly ,  Jean-Marc Engasser ,  Mohamed Ghoul

    IPC: A61K8/00 ,  A61K8/11 ,  A61K8/72 ,  A61K8/73 ,  A61K8/99 ,  A61Q17/04 ,  A61Q19/00 ,  C08B37/18 ,  C12N1/00 ,  C12N1/06 ,  C12N1/14 ,  C12P19/04 ,  C12R1/86 ,  A61K7/035 ,  C12P1/02

    CPC classification number: A61K8/73 ,  A61Q19/00 ,  C12N1/063 ,  C12P19/04 ,  A61Q17/04 ,  Y10S435/911 ,  Y10S435/921 ,  Y10S435/94

    Abstract: A process is provided for the production of glycogens or an extract rich in glycogens from yeast cells, and a cosmetic composition containing them. A given quantity of yeast cells, from a specific culture or recovered as residues of a fermentation process, is subjected to an operation of enrichment in intracellular glycogens by culturing in two phases in the presence of a carbon source. The metabolism of the yeast cells is then stopped. The membranes of the yeast cells are then at least partially disintegrated to free intracellular substances, and the freed intracellular substances are subjected to at least one precipation to precipitate glycogens. A cosmetic composition comprising the glycogens is formulated in admixture with a dermatologically acceptable excipient.

    Abstract translation: PCT No.PCT / FR96 / 02008 Sec。 371日期1998年6月15日第 102（e）1998年6月15日PCT PCT 1996年12月13日PCT公布。 公开号WO97 / 21828 日期1996年6月19日提供了用于从酵母细胞中制备糖原或富含糖原的提取物的方法和含有它们的化妆品组合物的方法。 给定量的来自特定培养物的酵母细胞或作为发酵过程的残留物回收的酵母细胞通过在碳源的存在下在两相中培养来进行细胞内糖原的富集操作。 然后停止酵母细胞的代谢。 然后将酵母细胞的膜至少部分地分解成游离细胞内物质，并且释放的细胞内物质经历至少一个沉淀以沉淀糖原。 含有糖原的化妆品组合物与皮肤病学可接受的赋形剂混合配制。

    Highly purified tocopheryl phosphate, process for producing the same, analytical method therefor and cosmetic
    4.
    发明授权
    Highly purified tocopheryl phosphate, process for producing the same, analytical method therefor and cosmetic 有权
    高纯度生育磷酸酯，其生产方法，分析方法和化妆品

    公开(公告)号：US6046181A

    公开(公告)日：2000-04-04

    申请号：US342228

    申请日：1999-06-29

    Applicant: Yutaka Oonishi ,  Tsutomu Nozawa ,  Takami Ooe ,  Keisuke Mano ,  Naoaki Misu ,  Yohei Kurata ,  Shinobu Ito ,  Eiji Ogata

    Inventor： Yutaka Oonishi ,  Tsutomu Nozawa ,  Takami Ooe ,  Keisuke Mano ,  Naoaki Misu ,  Yohei Kurata ,  Shinobu Ito ,  Eiji Ogata

    IPC: A61K8/02 ,  A61K8/67 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q5/02 ,  A61Q7/00 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/10 ,  C07F9/655 ,  G01N30/02 ,  G01N30/88 ,  G01N33/82 ,  A61K7/035 ,  A61K7/00 ,  A61K7/02 ,  A61K7/021 ,  A61K7/027

    CPC classification number: G01N33/82 ,  A61K8/0212 ,  A61K8/678 ,  A61Q19/00 ,  C07F9/65522 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q11/00 ,  A61Q19/10 ,  A61Q5/02 ,  A61Q7/00 ,  G01N2030/884 ,  G01N30/02 ,  Y10S514/846

    Abstract: Disclosed herein are a highly purified tocopheryl phosphate and/or a salt thereof (tocopheryl phosphates) wherein a P,P'-bistocopheryl hypophosphate and/or a salt thereof (P,P'-bistocopheryl diphoshates) is contained in a proportion of not higher than 3% by weight; a process for producing a highly purified tocopheryl phosphate and/or a salt thereof, which comprises the steps of reacting a tocopherol with an oxyphosphorus trihalide followed by treating with an acid or basic aqueous solution to thereby form tocopheryl phosphates (i) in which P,P'-bistocopheryl diphoshates (ii) formed as by-products are contained, hydrolyzing the P,P'-bistocopheryl diphoshates (ii) under acid condition, and, optionally, rendering the hydrolyzate neutral or basic under basic condition; and a method of analyzing tocopheryl phosphates, comprising analyzing a sample containing components (i) and (ii) with the use of a high-performance liquid chromatograph column packed with a gel of a polymethacrylate having, bonded thereto, long-chain alkyl groups. None or only an extremely minute amount of P,P'-bistocopheryl diphoshates are contained in the highly purified tocopheryl phosphates, so that the highly purified tocopheryl phosphates exhibit antioxidant and blood circulation promoting effects, have excellent water solubility, are powdery so that the handling thereof is extremely easy, are free from cutaneous irritation and allergenecity and ensure dermal safety. Therefore, the highly purified tocopheryl phosphates are useful as cosmetic ingredients. The amounts of components (i) and (ii) can be simply measured with high accuracy by the above method.

    Abstract translation: 本文公开了高纯度的生育磷酸酯和/或其盐（生育磷酸酯），其中P，P'-二生育酚低磷酸盐和/或其盐（P，P'-二生育基二磷酸酯）的含量不高于 超过3％重量; 一种生产高纯度生育磷酸酯和/或其盐的方法，其包括使生育酚与三卤氧磷反应，然后用酸或碱性水溶液处理，从而形成生育磷酸酯（i），其中P， 含有作为副产物形成的P'-二生育基二磷酸酯（ⅱ），在酸性条件下水解P，P'-二生育基二磷酸酯（ⅱ），任选地在碱性条件下使水解产物中性或碱性。 以及分析生育磷酸酯的方法，包括使用填充有与其键合的聚甲基丙烯酸酯的凝胶的高效液相色谱柱分析含有成分（i）和（ii）的样品的长链烷基。 高纯度的生育磷酸酯中没有或仅有非常少量的P，P'-二生育基二磷酸酯，因此高纯度的生育磷酸酯表现出抗氧化和促进血液循环的作用，具有优异的水溶性，是粉末状的， 它非常容易，没有皮肤刺激和过敏原，并确保皮肤安全。 因此，高纯度的生育磷酸酯可用作化妆品成分。 组分（i）和（ii）的量可以通过上述方法以高精度简单地测量。

    Sand removing body powder
    7.
    发明授权
    Sand removing body powder 失效
    除砂体粉

    公开(公告)号：US5824294A

    公开(公告)日：1998-10-20

    申请号：US950689

    申请日：1997-10-15

    Applicant: Trevor David Abramson ,  Adele Abramson

    Inventor： Trevor David Abramson ,  Adele Abramson

    IPC: A61K8/73 ,  A61Q1/12 ,  A61K7/035 ,  A61K33/00 ,  A61K33/42 ,  A61K47/00

    CPC classification number: A61Q1/12 ,  A61K8/732

    Abstract: A body powder composition useful for removing sand adhered to a user's body. The composition comprises a major amount of cornstarch. A related method for removing sand off the body is also disclosed comprising the steps of liberally applying a powder composition containing a major amount of cornstarch to an area of the body having sand adhered thereto; rubbing said composition on said area; and wiping said composition and said sand off the area using one's hands or a towel or the like.

    Abstract translation: 用于去除附着在使用者身上的沙子的身体粉末组合物。 该组合物包含主要量的玉米淀粉。 还公开了一种从身体上除去沙子的相关方法，包括以下步骤：将含有大量玉米淀粉的粉末组合物自由施加到具有粘附在其上的沙子的身体区域; 在所述区域上摩擦所述组合物; 并用手或毛巾等将所述组合物和所述沙子擦去所述区域。

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