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公开(公告)号：US20230193332A1
公开(公告)日：2023-06-22
申请号：US17883115
申请日：2022-08-08
发明人： Ryan M. Summers , Shelby Mills , Meredith Mock
CPC分类号： C12P17/14 , C12N9/0071 , C12Y114/00
摘要： The present disclosure relates to mutant enzymes and bacterial strains constructed to produce paraxanthine and 7-methylxanthine from caffeine and methods for the manufacture and use thereof.
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公开(公告)号：US20180346953A1
公开(公告)日：2018-12-06
申请号：US15974429
申请日：2018-05-08
申请人： EVOLVA SA
发明人： Yaoquan Liu , Jorgen Hansen , Jens Houghton-Larsen , Muthuswamy Panchapagesa Murali , Sathish Kumar , Nina Nicoline Rasmussen
IPC分类号： C12P33/20 , C12N9/02 , C12P33/12 , C12P33/08 , C12P33/00 , C12P19/56 , C12P19/18 , C12N9/90 , C12N9/14 , C12N9/10 , C12N15/80
CPC分类号： C12P33/20 , C12N9/0071 , C12N9/0073 , C12N9/1048 , C12N9/14 , C12N9/90 , C12N15/80 , C12P19/18 , C12P19/56 , C12P33/00 , C12P33/08 , C12P33/12 , C12Y114/00 , C12Y114/13132 , C12Y303/00 , C12Y504/99033
摘要： The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
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公开(公告)号：US20170369896A2
公开(公告)日：2017-12-28
申请号：US15469731
申请日：2017-03-27
CPC分类号： C12N15/8251 , A01H3/04 , C07K14/415 , C12N7/00 , C12N9/0071 , C12N9/0077 , C12N15/67 , C12N15/8218 , C12N15/8243 , C12P17/188 , C12Q1/6876 , C12Q2600/156 , C12Q2600/158 , C12Y114/00
摘要： This disclosure relates to the isolation and sequencing of nucleic acid molecules that encode cytochrome P450 polypeptides from a Papaver somniferum cultivar; uses in the production of noscapine and identification of poppy cultivars that include genes that comprise said nucleic acid molecules.
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4.发明申请公开(公告)号：US20170226122A1
公开(公告)日：2017-08-10
申请号：US15492180
申请日：2017-04-20
发明人： Rudi Fasan , Kai-Dong Zhang
IPC分类号： C07D493/18 , C12P17/18 , C12N9/02
CPC分类号： C07D493/18 , C07D491/18 , C12N9/0042 , C12N9/0071 , C12P17/181 , C12Y106/02004 , C12Y114/00
摘要： Derivatives of the antimalarial agent artemisinin, compositions comprising the derivatives, methods for preparing the derivatives, and their uses in pharmaceutical compositions intended for the treatment of parasitic infections are provided. Methods are provided for the production of artemisinin derivatives via functionalization of positions C7 and C6a, and optionally, in conjunction with modifications at positions C10 and C9, via chemoenzymatic methods. Recombinant cytochrome P450 polypeptides are also provided for use in the methods. The artemisinin derivatives can be used for the treatment of malaria and other parasitic infections, alone or in combination with other antiparasitic drugs.
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公开(公告)号：US20170198299A1
公开(公告)日：2017-07-13
申请号：US15469731
申请日：2017-03-27
CPC分类号： C12N15/8251 , A01H3/04 , C07K14/415 , C12N7/00 , C12N9/0071 , C12N9/0077 , C12N15/67 , C12N15/8218 , C12N15/8243 , C12P17/188 , C12Q1/6876 , C12Q2600/156 , C12Q2600/158 , C12Y114/00
摘要： This disclosure relates to the isolation and sequencing of nucleic acid molecules that encode cytochrome P450 polypeptides from a Papaver somniferum cultivar; uses in the production of noscapine and identification of poppy cultivars that include genes that comprise said nucleic acid molecules.
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6.发明授权公开(公告)号：US09663532B2
公开(公告)日：2017-05-30
申请号：US14438833
申请日：2013-10-28
发明人： Rudi Fasan , Kai-Dong Zhang
IPC分类号： C07D491/18 , C07D493/18 , C12N9/00 , C12N9/02
CPC分类号： C07D493/18 , C07D491/18 , C12N9/0042 , C12N9/0071 , C12P17/181 , C12Y106/02004 , C12Y114/00
摘要： Derivatives of the antimalarial agent artemisinin, compositions comprising the derivatives, methods for preparing the derivatives, and their uses in pharmaceutical compositions intended for the treatment of parasitic infections are provided. Methods are provided for the production of artemisinin derivatives via functionalization of positions C7 and C6a, and optionally, in conjunction with modifications at positions C10 and C9, via chemoenzymatic methods. Recombinant cytochrome P450 polypeptides are also provided for use in the methods. The artemisinin derivatives can be used for the treatment of malaria and other parasitic infections, alone or in combination with other antiparasitic drugs.
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公开(公告)号：US09447428B2
公开(公告)日：2016-09-20
申请号：US13945741
申请日：2013-07-18
发明人： Ronald J. Brinker , Wen C. Burns , Paul C. C. Feng , Anju Gupta , Sio-Wai Hoi , Marianne Malven , Kunsheng Wu
CPC分类号： C12N15/8274 , A23D9/00 , A23L11/03 , C12N9/0071 , C12Q1/6895 , C12Y114/00
摘要： The invention provides a transgenic soybean event MON 87708 plant and plants, plant cells, seeds, plant parts, and commodity products derived from event MON 87708. The invention also provides polynucleotides specific for event MON 87708 and plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides specific for event MON 87708. The invention also provides methods related to event MON 87708.
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公开(公告)号：US20150322473A1
公开(公告)日：2015-11-12
申请号：US14442694
申请日：2013-12-04
申请人： EVOLVA SA
发明人： Yaoquan Liu , Jorgen Hansen , Jens Houghton-Larsen , Muthuswamy Panchapagesa Murali , Sathish Kumar , Nina Nicoline Rasmussen
CPC分类号： C12P33/20 , C12N9/0071 , C12N9/0073 , C12N9/1048 , C12N9/14 , C12N9/90 , C12N15/80 , C12P19/18 , C12P19/56 , C12P33/00 , C12P33/08 , C12P33/12 , C12Y114/00 , C12Y114/13132 , C12Y303/00 , C12Y504/99033
摘要： The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
摘要翻译： 本发明涉及借助于酶的方法来生产芒果苷。 特别地，本发明提出了可用于罗汉果苷生产的各种生物合成途径，并提供了可用于罗汉果苷生产的酶。 此外，本发明提供可用于实施本发明方法的重组宿主。
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公开(公告)号：US11949878B2
公开(公告)日：2024-04-02
申请号：US18097019
申请日：2023-01-13
发明人： Michael Horowitz
IPC分类号： H04N19/174 , C12N9/02 , C12P17/14 , H04N19/103 , H04N19/105 , H04N19/117 , H04N19/137 , H04N19/139 , H04N19/159 , H04N19/172 , H04N19/176 , H04N19/196 , H04N19/436 , H04N19/44 , H04N19/46 , H04N19/50 , H04N19/61 , H04N19/70 , H04N19/80 , H04N19/82 , H04N19/91
CPC分类号： H04N19/139 , C12N9/0071 , C12P17/14 , C12Y114/00 , H04N19/103 , H04N19/105 , H04N19/117 , H04N19/137 , H04N19/159 , H04N19/172 , H04N19/174 , H04N19/196 , H04N19/436 , H04N19/44 , H04N19/46 , H04N19/50 , H04N19/61 , H04N19/70 , H04N19/80 , H04N19/82 , H04N19/91
摘要： Described is picture segmentation through columns and slices in video encoding and decoding. A video picture is divided into a plurality of columns, each column covering only a part of the video picture in a horizontal dimension. All coded tree blocks (“CTBs”) belonging to a slice may belong to one or more columns. The columns may be used to break the same or different prediction or in-loop filtering mechanisms of the video coding, and the CTB scan order used for encoding and/or decoding may be local to a column. Column widths may be indicated in a parameter set and/or may be adjusted at the slice level. At the decoder, column width may be parsed from the bitstream, and slice decoding may occur in one or more columns.
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公开(公告)号：US20230242954A1
公开(公告)日：2023-08-03
申请号：US18097019
申请日：2023-01-13
发明人： Michael Horowitz
CPC分类号： C12P17/14 , C12N9/0071 , C12Y114/00
摘要： Described is picture segmentation through columns and slices in video encoding and decoding. A video picture is divided into a plurality of columns, each column covering only a part of the video picture in a horizontal dimension. All coded tree blocks (“CTBs”) belonging to a slice may belong to one or more columns. The columns may be used to break the same or different prediction or in-loop filtering mechanisms of the video coding, and the CTB scan order used for encoding and/or decoding may be local to a column. Column widths may be indicated in a parameter set and/or may be adjusted at the slice level. At the decoder, column width may be parsed from the bitstream, and slice decoding may occur in one or more columns.
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