-
公开(公告)号：US20250049957A1
公开(公告)日：2025-02-13
申请号：US18722690
申请日：2022-12-22
Applicant: University of Rochester , University of Copenhagen , Karolinska Institutet
Inventor： Maiken Nedergaard , Barbara K. Mathiesen , Christopher R. Cederroth , Barbara Canlon
IPC: A61K48/00 , A61P27/16 , C07K14/705 , C12N15/86
Abstract: This disclosure relates to delivery of various agents to the inner ear of a subject.
-
公开(公告)号：US20250025049A1
公开(公告)日：2025-01-23
申请号：US18765983
申请日：2024-07-08
Applicant: UNIVERSITY OF ROCHESTER
Inventor： Kevin PARKER
Abstract: A reverberant shear wave field in an object such as a patient's body or organ causes deformations in one or more selected directions measured with an imaging modality such as ultrasound or MR equipment or other imaging equipment, to estimate displacements in one or more selected directions over time increments and then viscoelastic properties such as stiffness or other parameters of the ROI.
-
公开(公告)号：US20250019702A1
公开(公告)日：2025-01-16
申请号：US18708790
申请日：2022-11-07
Applicant: University of Rochester
Inventor： Peng YAO , Omar HEDAYA
IPC: C12N15/113 , A61P9/00
Abstract: The present application provides compositions and methods for treating cardiac hypertrophy. In one embodiment, the composition comprises an antisense oligonucleotide 10-50 nucleotides in length, wherein the antisense oligonucleotide is capable of forming a double-stranded structure with a target region downstream of a start codon of an upstream open reading frame (uORF) resided within an mRNA of GATA4, wherein the target region spans a double-stranded stem of a stem-loop structure downstream of the GATA4 uORF start codon
-
公开(公告)号：US20240390399A1
公开(公告)日：2024-11-28
申请号：US18778820
申请日：2024-07-19
Applicant: Indiana University Research and Technology Corporation , University of Rochester , The U.S.A. of America As Represented by the Department of Veterans Affairs Office of General Council
Inventor： Teresita M. Bellido , G. David Roodman , Jesus Delgado-Calle , Robert K. Boeckman , Frank H. Ebetino
IPC: A61K31/664 , A61K38/29 , A61K45/06 , A61P35/00 , C07F9/38
Abstract: Various aspects and embodiments disclosed herein relate generally to the modelling, treatment, reducing resistence to the treatment, prevention, and diagnosis of diseases/symptoms induced by multiple myeloma. Embodiments include methods of treating a bone related disease, comprising the steps of: administering to a subject at least one therapeutically effective dose of a compound disclosed herein.
-
公开(公告)号：US20240346735A1
公开(公告)日：2024-10-17
申请号：US18633750
申请日：2024-04-12
Applicant: University of Rochester
Inventor： Luchuan Song , Chenliang Xu
CPC classification number: G06T13/40 , G06T3/18 , G06T7/20 , G06T7/70 , G06T17/20 , G06V10/44 , G06V40/174 , H04N21/816
Abstract: Features described herein pertain to generative machine learning, and more particularly, to machine learning techniques for generating virtual characters. A video that depicts a first subject and includes an audio component that corresponds to speech spoken by the first subject and an image that depicts a second subject are provided to and used by one or more machine learning models to generate a video that depicts the second subject. The second subject can blink and exhibit emotional characteristic and reactions that are responsive to the speech spoken by the first subject and/or a characteristic of the first subject such as a facial expression and/or head pose motion. The generated video can be displayed and/or stored where it can be later retrieved.
-
Patent Agency Ranking
6.发明公开公开(公告)号：US20240342717A1
公开(公告)日：2024-10-17
申请号：US18607405
申请日：2024-03-15
Applicant: SiMPore Inc. , University of Rochester
Inventor： James A. Roussie , James L. McGrath , Richard E. Waugh , Kilean S. Lucas , Joshua J. Miller
IPC: B01L3/00 , G01N1/40 , G01N33/537
CPC classification number: B01L3/502753 , G01N1/4077 , G01N33/537 , B01L2300/0681 , G01N2001/4088
Abstract: Provided are methods, devices, and kits for the isolation and detection of one or more analytes of interest from a biological sample using microslit filter membranes. In various examples, the methods use capture particles and binding agents for specific recognition of one or more analytes of interest.
-
公开(公告)号：US12096193B2
公开(公告)日：2024-09-17
申请号：US18341248
申请日：2023-06-26
Applicant: UNIVERSITY OF ROCHESTER
CPC classification number: H04R3/14 , H04R3/04 , H04R7/045 , H04R9/06 , H04R17/00 , H04R2440/05 , H04R2440/07
Abstract: Systems and methods of driving plate loudspeakers with different parameters based on frequency region in a way similar to typical cone driver crossover networks are described. These systems and methods may be implemented using arrays of independently controlled drivers which allow a designer to emphasize or de-emphasize certain modes in certain frequency bands. Tuning the characteristics of the plate's motion can also affect the acoustical properties in a larger space rather than just at a single location. The systems and methods described herein can grant a designer a degree of control over the characteristics and performance of the plate.
-
公开(公告)号：US12083168B2
公开(公告)日：2024-09-10
申请号：US17719580
申请日：2022-04-13
Applicant: University of Miami , University of Rochester , UCL Business LTD
Inventor： Stephan L. Zuchner , Adriana Rebelo , Andrea Cortese , Rong Grace Zhai , David N. Herrmann
IPC: A61K38/44 , A61K31/198 , A61K31/352 , A61K31/4184 , A61K31/4188 , A61K31/426 , A61K31/428 , A61K31/473 , A61K31/499 , A61K31/502 , A61K31/517 , A61K31/7105 , A61K38/46 , A61K48/00 , A61P25/28 , C12N9/04 , C12N15/113 , C12N15/86 , C12Q1/6883 , G01N33/66
CPC classification number: A61K38/443 , A61K31/198 , A61K31/352 , A61K31/4184 , A61K31/4188 , A61K31/426 , A61K31/428 , A61K31/473 , A61K31/499 , A61K31/502 , A61K31/517 , A61K31/7105 , A61K38/465 , A61K48/005 , A61P25/28 , C12N9/0006 , C12N15/1137 , C12N15/86 , C12Q1/6883 , C12Y101/01014 , G01N33/66 , C12N2310/11 , C12N2750/14143 , C12Q2600/156
Abstract: The present disclosure relates to methods of detecting and treating inherited neuropathy.
-
公开(公告)号：US20240277868A1
公开(公告)日：2024-08-22
申请号：US18560828
申请日：2022-05-13
Applicant: UNIVERSITY OF ROCHESTER , THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , ALBERT EINSTEIN COLLEGE OF MEDICINE
Inventor： Vera GORBUNOVA , Andrei SELUANOV , Yousin SUH
CPC classification number: A61K48/0016 , A61K38/45 , A61P35/00 , A61P39/00 , C12N9/1029
Abstract: An isolated nucleic acid molecule encoding a variant of sirtuin 6 (SIRT6) having at least 75% identity with sequence SEQ ID NO: 1, the variant having at least one mutation selected from a N308K substitution and a A313S substitution with respect to sequence SEQ ID NO: 1. Also, means for the regulation of ageing, and/or senescence, and/or lifespan in an individual. Further, means for the repair of double strand breaks in a cell. Finally, means for the prevention and/or the treatment of an age-related disease.
-
10.发明公开公开(公告)号：US20240240205A1
公开(公告)日：2024-07-18
申请号：US18560338
申请日：2022-05-20
Applicant: UNIVERSITY OF ROCHESTER
Inventor： Brian M. WARD , Stephanie MONTICELLl , Peter BRYK
IPC: C12N15/86 , A61K39/00 , A61K39/215 , A61P31/14
CPC classification number: C12N15/86 , A61K39/215 , A61P31/14 , A61K2039/5254 , A61K2039/5256
Abstract: A method for inducing an immune response to an antigen in a subject is disclosed. The method comprises the step of administering to the subject an effective amount of a recombinant vaccinia virus in which the coding sequence for the extracellular virion protein F13 has been replaced with the coding sequence for MC021, a molluscum contagiosum virus homolog of F13, wherein the recombinant vaccinia virus comprises a nucleic acid encoding an immunogenic epitope of the antigen.
-
-
-
-
-
-
-
-
-
Search Results
780
records
(took 0.032 seconds)
