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1.
公开(公告)号:US11931739B2
公开(公告)日:2024-03-19
申请号:US16639471
申请日:2018-08-16
IPC分类号: B01L3/00 , G01N1/40 , G01N33/537
CPC分类号: B01L3/502753 , G01N1/4077 , G01N33/537 , B01L2300/0681 , G01N2001/4088
摘要: Provided are methods, devices, and kits for the isolation and detection of one or more analytes of interest from a biological sample using microslit filter membranes. In various examples, the methods use capture particles and binding agents for specific recognition of one or more analytes of interest.
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2.
公开(公告)号:US20210129146A1
公开(公告)日:2021-05-06
申请号:US16639471
申请日:2018-08-16
IPC分类号: B01L3/00 , G01N1/40 , G01N33/537
摘要: Provided are methods, devices, and kits for the isolation and detection of one or more analytes of interest from a biological sample using microslit filter membranes. In various examples, the methods use capture particles and binding agents for specific recognition of one or more analytes of interest.
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3.
公开(公告)号:US20240342717A1
公开(公告)日:2024-10-17
申请号:US18607405
申请日:2024-03-15
IPC分类号: B01L3/00 , G01N1/40 , G01N33/537
CPC分类号: B01L3/502753 , G01N1/4077 , G01N33/537 , B01L2300/0681 , G01N2001/4088
摘要: Provided are methods, devices, and kits for the isolation and detection of one or more analytes of interest from a biological sample using microslit filter membranes. In various examples, the methods use capture particles and binding agents for specific recognition of one or more analytes of interest.
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公开(公告)号:US10668436B2
公开(公告)日:2020-06-02
申请号:US15772488
申请日:2016-10-31
申请人: SiMPore Inc.
IPC分类号: B01D67/00 , B01D69/02 , B01D61/24 , B01D69/12 , B01D71/02 , B81C1/00 , C12M1/12 , C12M1/26 , G01N1/34 , G03F7/00 , B01D61/18 , C23F1/04
摘要: Provided are monolithic structures comprising one or more suspended, nanoporous membranes that are in contact with one or more fluidic cavities, methods of making same, and exemplary uses of same. The monolithic structures can be formed using a transmembrane etch. The monolithic structures can be used, as examples, as filters and filtration modules in microfluidic devices, dialysis devices, and concentration devices in laboratory, industrial, and medical processes.
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公开(公告)号:US11119013B2
公开(公告)日:2021-09-14
申请号:US16600322
申请日:2019-10-11
申请人: SiMPore, Inc.
摘要: Provided are methods, devices, and kits for the isolation of extracellular vesicles using silicon nanomembranes. A method for EV isolation includes the steps of collecting a biofluid sample, contacting the biofluid sample with a pre-filtration membrane, thereby forming a first filtrate and a first retentate, optionally, washing the first retentate of the pre-filtration membrane, contacting the first filtrate from the pre-filtration membrane with a capture membrane, thereb forming a second filtrate and a second retentate, optionally, washing the second retentate, and eluting the second retentate from the capture membrane or lysing the second retentate to recover the contents.
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公开(公告)号:US11635357B2
公开(公告)日:2023-04-25
申请号:US17382505
申请日:2021-07-22
申请人: SiMPore Inc.
摘要: Provided are methods, devices, and kits for the isolation of extracellular vesicles using silicon nanomembranes. A method for EV isolation includes the steps of collecting a biofluid sample, contacting the biofluid sample with a pre-filtration membrane, thereby forming a first filtrate and a first retentate, optionally, washing the first retentate of the pre-filtration membrane, contacting the first filtrate from the pre-filtration membrane with a capture membrane, thereby forming a second filtrate and a second retentate, optionally, washing the second retentate, and eluting the second retentate from the capture membrane or lysing the second retentate to recover the contents.
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公开(公告)号:US20210215584A1
公开(公告)日:2021-07-15
申请号:US17268330
申请日:2019-08-16
申请人: SIMPORE INC.
发明人: Jared A. Carter , James A. Roussie
摘要: Provided are methods, devices, and kits for the isolation and enumeration of one or more components of interest within a liquid sample using microslit filter membranes. This disclosure relates to the enumeration of components within a sample of interest, and more particularly, the capture of such components by efficient isolation using microslit filters with high permeation capacity and precision molecular cut-off characteristics.
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