SEPARATION/DETECTION COLUMN AND KIT THEREOF
    4.
    发明申请
    SEPARATION/DETECTION COLUMN AND KIT THEREOF 有权
    分离/检测柱及其套件

    公开(公告)号:US20130089468A1

    公开(公告)日:2013-04-11

    申请号:US13703475

    申请日:2011-07-08

    IPC分类号: G01N21/64 G01N30/02

    摘要: Disclosed is a separation/detection column that can detect a component separated by a separating agent having optical responsivity which is the same as that of a component in a sample. The separation/detection column is configured by filling one end of a tube 1, having ultraviolet transparency, with a first filler that has ultraviolet responsivity and a separation ability to separate the component in the sample, and by filling the other end of the tube 1 with a second filler that has ultraviolet responsivity which is different from that of the first filler and does not have the separation ability via a spacer 4 constituted by quartz wool, and moreover by inserting an end cap 5 constituted by quartz wool into the other end of the tube 1.

    摘要翻译: 公开了一种分离/检测柱,其可以检测由具有与样品中的组分相同的光学响应性的分离剂分离的组分。 分离/检测柱通过将具有紫外线透明度的管1的一端填充有具有紫外线响应性的第一填料和分离样品中的组分的分离能力以及通过填充管1的另一端而构成 具有与第一填料不同的紫外线响应性的第二填料,并且不具有通过由石英棉构成的间隔物4的分离能力,而且通过将由石英棉构成的端盖5插入到石英棉的另一端 管1。

    Cast membrane structures for sample preparation
    5.
    发明授权
    Cast membrane structures for sample preparation 有权
    用于样品制备的铸膜结构

    公开(公告)号:US06635201B1

    公开(公告)日:2003-10-21

    申请号:US09291355

    申请日:1999-04-14

    IPC分类号: B29C6500

    摘要: A method for casting-in-place composite and/or non-filled structures which are useful as sorptive or reactive media or for size-based separations. Any particular housing size or configuration can be used, and the inclusion of a large amount of adsorptive particles in polymer is achieved while still maintaining the membrane three dimensional structure. In a first preferred embodiment, the composite structures comprise particles entrapped within a porous polymeric substrate, and are cast in-place into a housing such as a pipette tip, thereby providing an effective platform for micromass handling. With the appropriate selection of particle chemistry, virtually any separation or purification operation can be conducted, including selective bind/elute chromatography operations, on sample mass loads less than 1 microgram in volumes of a few microliters, as well as larger mass loads and volumes. The present invention also encompasses the composite structures as well as sample preparation devices containing the same. In a second structures are cast in situ in a suitable housing and can be used for size-based separations wherein the cast structure acts as a semi-permeable barrier. The present invention also encompasses these structures as well as housings containing these structures.

    摘要翻译: 用于现浇复合和/或非填充结构的方法,其可用作吸附或反应介质或基于尺寸的分离。 可以使用任何特定的壳体尺寸或构型,并且在保持膜三维结构的同时实现在聚合物中包含大量吸附颗粒。 在第一优选实施方案中,复合结构包括捕获在多孔聚合物基底内的颗粒,并且被放置在诸如移液管尖端的壳体中,从而为微粒处理提供有效的平台。 通过适当的颗粒化学选择,可以进行任何分离或纯化操作,包括选择性结合/洗脱色谱操作,样品质量负载小于1微克体积的几微升,以及较大的质量负载和体积。 本发明还包括复合结构以及含有该结构的样品制备装置。 在第二结构中,在合适的壳体中原位铸造,并且可以用于基于尺寸的间隔,其中铸造结构用作半渗透屏障。 本发明还包括这些结构以及包含这些结构的壳体。