公开(公告)号：US20230321400A1

公开(公告)日：2023-10-12

申请号：US18044424

申请日：2021-09-02

申请人： JANSSEN BIOTECH, INC.

发明人： Rudolph CEDRO, Jr. ,  Anthony R. DIUBALDI ,  James A. FLEMING ,  Daniel OLSEN

IPC分类号： A61M25/01 ,  A61M25/00

CPC分类号： A61M25/0136 ,  A61M25/0084 ,  A61M2025/0089 ,  A61B2017/003

摘要： The deflectable tip catheters can be used with a primary delivery system (e.g., a bronchoscope, endoscope, or other surgical access device) to access a certain target tissue, such as a tumor (e.g., a lung tumor). The primary access device provides initial access and the deflectable tip catheter can be passed through the primary access device to reach the target tissue which is not otherwise accessible by the primary access device. The deflectable tip catheters have an internal bore free of obstructions such that a drug delivery device (e.g., a needle) or a diagnostic tool can be passed therethrough to directly access the target tissue.

公开(公告)号：US10080875B2

公开(公告)日：2018-09-25

申请号：US14955384

申请日：2015-12-01

申请人： Medtronic Vascular, Inc.

发明人： Jeffery Argentine ,  Samuel Robaina

IPC分类号： A61M25/10 ,  A61M39/10 ,  A61B17/12 ,  A61F2/958 ,  A61B17/22

CPC分类号： A61M25/10185 ,  A61B17/12113 ,  A61B17/12136 ,  A61B17/12186 ,  A61B2017/00539 ,  A61B2017/1205 ,  A61B2017/22001 ,  A61B2017/22062 ,  A61B2017/22069 ,  A61B2090/0807 ,  A61F2/958 ,  A61F2002/9517 ,  A61M5/178 ,  A61M25/0097 ,  A61M25/10182 ,  A61M25/10187 ,  A61M25/104 ,  A61M39/105 ,  A61M2025/0089 ,  A61M2025/109 ,  A61M2205/0266 ,  A61M2205/581 ,  A61M2205/583

摘要： A handle component of a medical device is disclosed for delivering a material to an enclosed cavity or space. The handle component includes a self-contained mechanism for holding the material and for providing or releasing the material to the enclosed cavity. The handle component also includes a pressure relief valve in fluid communication with the mechanism and the enclosed cavity. The pressure relief valve is configured to indicate when delivery of the material to the enclosed cavity reaches a preselected or set pressure and to thereby assure precise filling of the enclosed cavity with the material.

公开(公告)号：US20170333130A1

公开(公告)日：2017-11-23

申请号：US15526945

申请日：2015-11-17

申请人： MedVASC AB

发明人： Michael ÅKESSON

IPC分类号： A61B18/24 ,  A61M25/00 ,  A61M25/01 ,  A61B18/00

CPC分类号： A61B18/24 ,  A61B2018/00345 ,  A61B2018/00404 ,  A61B2018/00577 ,  A61M25/008 ,  A61M25/0084 ,  A61M25/01 ,  A61M2025/0034 ,  A61M2025/0089 ,  A61M2025/0188

摘要： A medical device to be inserted in a defect blood vessel, body cavity, or body duct for treatment thereof is disclosed, wherein it comprises an essentially cylindrically formed elongated resilient sheath device (2) wherein it has a distal end (3) and a proximal end (4), wherein said sheath device (2) along its circumferential surface in the axial direction is provided with a slotted opening (5) having connection with a first bore (6) arranged in the axial direction of said sheath device (2), said first bore (6) having the ability to house an elongated fiber body (7), wherein said sheath device (2) has the ability to be clamped around a major part of the perimeter of said fiber body (7), and wherein said sheath device (2) in its axial direction also is provided with a second bore (8) having the ability to house an injection means (9), as well as a kit containing said medical device, and a method for treatment of defective blood vessels, body cavities, and body ducts by use of said medical device.

公开(公告)号：US09795763B2

公开(公告)日：2017-10-24

申请号：US14427031

申请日：2013-09-04

申请人： EMORY UNIVERSITY ,  CELL PRECISION, LLC

发明人： Michael L. Wach ,  Raymond P. Vito ,  Jack Griffis ,  W. Robert Taylor

IPC分类号： A61M5/178 ,  A61M25/00 ,  A61B17/3205 ,  A61M5/32

CPC分类号： A61M25/0084 ,  A61B17/3205 ,  A61M5/3204 ,  A61M25/0082 ,  A61M2025/0087 ,  A61M2025/0089 ,  A61M2025/0096 ,  A61M2210/125

摘要： Delivery devices, systems, and methods are configured to enhance retention of a therapeutic agent delivered at a treatment site, for example, via impeding agent backflow. A device may include sheath having a first end, a second end, and a length between the first end and the second end. The sheath may include an outer diameter and an inner channel between the first end and the second end, and at least one penetrating member configured to form a channel at the treatment site. The device may include an elongate member having a first end, a second end, and a length between the first end and the second end, the elongate member being configured to move relative to the sheath. The elongate member may be configured to control the movement of the penetrating member with respect to the sheath.

公开(公告)号：US20170157035A1

公开(公告)日：2017-06-08

申请号：US14714131

申请日：2015-05-15

申请人： Mercator MedSystems, Inc. ,  Abraxis BioScience, LLC

发明人： Kirk SEWARD ,  Neil P. DESAI

IPC分类号： A61K9/00 ,  A61M25/00 ,  A61M25/10 ,  A61K31/436

CPC分类号： A61K9/0019 ,  A61K31/436 ,  A61K38/38 ,  A61K38/385 ,  A61K47/643 ,  A61K47/6921 ,  A61K47/6931 ,  A61M25/0084 ,  A61M25/104 ,  A61M2025/0089

摘要： The present invention provides methods of delivering a composition comprising nanoparticles that comprise a macrolide and an albumin by directly injecting the nanoparticle composition into the blood vessel wall or the tissue surrounding the blood vessel wall. The methods can be used for inhibiting negative remodeling or vascular fibrosis in the blood vessel and are useful for treating various diseases.

公开(公告)号：US20170151029A1

公开(公告)日：2017-06-01

申请号：US15283667

申请日：2016-10-03

申请人： UNIVERSITY OF IOWA RESEARCH FOUNDATION

发明人： Steven Richard Mickelsen

IPC分类号： A61B34/00 ,  A61M25/09 ,  A61M25/06 ,  A61B18/14 ,  A61M25/01

CPC分类号： A61M39/10 ,  A61B5/0538 ,  A61B5/4833 ,  A61B17/22004 ,  A61B18/02 ,  A61B18/1206 ,  A61B18/1492 ,  A61B18/1815 ,  A61B18/20 ,  A61B34/73 ,  A61B2017/00876 ,  A61B2018/00363 ,  A61B2018/00375 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/00839 ,  A61B2018/128 ,  A61B2018/1467 ,  A61B2034/731 ,  A61B2217/005 ,  A61B2218/002 ,  A61M25/0127 ,  A61M25/0169 ,  A61M25/0606 ,  A61M25/09 ,  A61M2025/0089

摘要： A percutaneous catheter system for use within the human body and an ablation catheter for ablating a selected tissue region within the body of a subject. The percutaneous catheter system can include two catheters that are operatively coupled to one another by magnetic coupling through a tissue structure. The ablation catheter can include electrodes positioned within a central portion. The ablation catheter is positioned such that the central portion of a flexible shaft at least partially surrounds the selected tissue region. Each electrode of the ablation catheter can be activated independently to apply ablative energy to the selected tissue region. The ablation catheter can employ high impedance structures to change the current density at specific points. Methods of puncturing through a tissue structure using the percutaneous catheter system are disclosed. Also disclosed are methods for ablating a selected tissue region using the ablation catheter.

公开(公告)号：US20170143317A1

公开(公告)日：2017-05-25

申请号：US15402544

申请日：2017-01-10

申请人： Spiration, Inc. d.b.a. Olympus Respiratory America

发明人： Peter Hoffman

IPC分类号： A61B10/04 ,  A61B1/018 ,  A61B8/08 ,  A61B8/00 ,  A61B10/02 ,  A61B1/267 ,  A61B8/12

CPC分类号： A61B10/04 ,  A61B1/018 ,  A61B1/2676 ,  A61B8/0841 ,  A61B8/12 ,  A61B8/445 ,  A61B10/0233 ,  A61B10/0266 ,  A61B17/3417 ,  A61B2010/045 ,  A61B2018/00023 ,  A61B2018/00095 ,  A61B2018/00208 ,  A61B2018/00541 ,  A61B2018/00577 ,  A61B2018/00595 ,  A61B2018/00982 ,  A61B2018/046 ,  A61B2090/376 ,  A61B2090/3966 ,  A61M2025/0087 ,  A61M2025/0089

摘要： Systems, methods, and devices for providing real-time imaging of tissue sampling. An ultrasound probe is received with a first lumen of a catheter and a tissue sampling device is received with a second lumen of the catheter. The catheter is received within a working channel of a bronchoscope. The ultrasound probe is a radial ultrasound probe that generates real-time ultrasound images of the tissue sampling device and surrounding tissue.

公开(公告)号：US20160256705A1

公开(公告)日：2016-09-08

申请号：US15158513

申请日：2016-05-18

申请人： Abbott Cardiovascular Systems Inc.

发明人： William E. WEBLER, JR. ,  Richard R. Newhauser

IPC分类号： A61N5/06 ,  A61B18/18 ,  A61M25/00

CPC分类号： A61N5/062 ,  A61B1/00163 ,  A61B1/00165 ,  A61B18/18 ,  A61B2018/1807 ,  A61M25/0084 ,  A61M25/0662 ,  A61M2025/0089 ,  A61M2025/0681 ,  A61N5/0601 ,  A61N2005/0602 ,  A61N2005/0612 ,  A61N2005/063

摘要： A delivery catheter for delivery, then photo-activation of photo sensitive material has a photo-sensitive substance-delivery part and an activation part. The catheter delivers substances such as biomaterials to a target site, followed by illumination of the target using optics located at the distal tip of the catheter which are optically coupled to an extracorporeal light source. The light may be delivered by a single or multi-lumen needle, or a separate light guide passed over the catheter.

摘要翻译： 用于递送的输送导管，然后感光材料的光激活具有光敏物质递送部分和激活部分。 该导管将诸如生物材料的物质输送到目标部位，随后使用位于导管的远侧末端的光学器件照射目标，其光学耦合到体外光源。 光可以由单个或多个针管或通过导管的独立导光器递送。

公开(公告)号：US20160114136A1

公开(公告)日：2016-04-28

申请号：US14986966

申请日：2016-01-04

申请人： B. Braun Melsungen AG

发明人： Kevin Woehr

IPC分类号： A61M25/06 ,  A61M25/00

CPC分类号： A61M25/0606 ,  A61M5/3232 ,  A61M25/0075 ,  A61M25/0084 ,  A61M25/0097 ,  A61M25/0631 ,  A61M39/1011 ,  A61M2025/0089

摘要： The present disclosure relates to a catheter device comprising a catheter hub in which a valve member is disposed, a needle fixed in a needle hub, the needle extending through the valve member in the catheter hub in a ready position, and a tubular receptacle in which the needle hub is displaceably guided and biased by a spring in a proximal direction relative to the receptacle, wherein the needle hub is releasably held in the ready position in the receptacle against the force of the spring by frictional force between needle circumference and catheter or catheter hub, which frictional force is reduced on retraction of the needle through the catheter hub such that the force of the spring prevails.

摘要翻译： 本公开内容涉及一种导管装置，其包括导管座，其中设置有阀构件，固定在针座中的针，针在导管座中的阀构件延伸到就绪位置，以及管状容器，其中 针座可相对于插座在近端方向上由弹簧可移位地引导和偏置，其中，针座通过针圆周与导管或导管之间的摩擦力克服弹簧的力而可释放地保持在容器中的就绪位置 轮毂，当通过导管座回缩针时摩擦力减小，使得弹簧的力占优势。

公开(公告)号：US20150231368A1

公开(公告)日：2015-08-20

申请号：US14501635

申请日：2014-09-30

申请人： BioCardia, Inc.

发明人： Wai Hsueh ,  Olin Jay Palmer ,  Scott Comiso ,  James B. Ross ,  Ken Vien ,  Julio Argentieri ,  Peter Altman

IPC分类号： A61M25/06 ,  A61M25/09

CPC分类号： A61M25/0084 ,  A61B2017/00247 ,  A61B2090/036 ,  A61M2025/0089

摘要： A needle-injection catheter includes a catheter body having a distal end, a proximal end, a stiff proximal portion, a flexible distal portion, and a delivery lumen extending therethrough. In a first embodiment, a straight injection needle extends coaxially from a distal tip of the flexible portion of the catheter body, and a plurality of penetration limiting elements positioned circumferentially about a base of the straight injection needle and configured to fold radially inwardly against a shaft of the needle when constrained in a tubular lumen and to extend radially outwardly when unconstrained. In a second embodiment, a helical needle extends from the distal tip of the flexible portion of the catheter body. The helical needle has at least one helical delivery lumen connected to receive an injectable substance from the delivery lumen of the catheter body.

摘要翻译： 针注射导管包括具有远端，近端，刚性近端部分，柔性远端部分和延伸通过其的输送腔的导管体。 在第一实施例中，直注射针从导管主体的柔性部分的远侧末端同轴延伸，以及多个穿透限制元件，其围绕直线注射针的基部周向定位，并被构造成径向向内折叠抵靠轴 当被限制在管状内腔中并且当不受约束时径向向外延伸。 在第二实施例中，螺旋针从导管主体的柔性部分的远端延伸。 螺旋针具有至少一个螺旋输送腔，其连接以从导管体的输送腔接收可注射物质。