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公开(公告)号：US20230233805A1
公开(公告)日：2023-07-27
申请号：US18130237
申请日：2023-04-03
Applicant: BioCardia, Inc.
Inventor： Wai Hsueh , Ken Vien , James B. Ross
IPC: A61M25/01
CPC classification number: A61M25/0136 , A61M25/0147 , A61B18/1492
Abstract: A bi-directional steerable catheter adapted for delivery into a patient's vasculature. The pull wires which are used to tension the deflectable segment of the steerable catheter are wound in parallel around the axis of the steerable catheter on opposite sides of the steerable catheter.
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公开(公告)号：US11357463B2
公开(公告)日：2022-06-14
申请号：US14793594
申请日：2014-01-08
Applicant: BioCardia, Inc.
Inventor： Cheryl Wong Po Foo , David Sanderson , Peter Altman
Abstract: Fluoroscopic imaging of a patient's heart is performed by positioning a patient in a sterile field and imaging the heart using a x-ray fluoroscopy system within the sterile to produce a two-dimensional image. The two-dimensional image is simultaneously displayed on an operative display within or adjacent the sterile filed and on a display of a remote image processor outside the operative field. The two-dimensional image of the remote display is manually marked or annotated to show anatomical or treatment information which is simultaneously shown on the operative display.
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公开(公告)号：US20220168544A1
公开(公告)日：2022-06-02
申请号：US17472629
申请日：2021-09-11
Applicant: BioCardia, Inc.
Inventor： Wai Hsueh , Ken Vien , James B. Ross
IPC: A61M25/01
Abstract: A bi-directional steerable catheter adapted for delivery into a patient's vasculature. The pull wires which are used to tension the deflectable segment of the steerable catheter are wound in parallel around the axis of the steerable catheter on opposite sides of the steerable catheter.
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公开(公告)号：US20210315532A1
公开(公告)日：2021-10-14
申请号：US17357649
申请日：2021-06-24
Applicant: BioCardia, Inc.
Inventor： Cheryl Wong Po Foo , David Sanderson , Peter Altman
Abstract: Fluoroscopic imaging of a patient's heart is performed by positioning a patient in a sterile field and imaging the heart using a x-ray fluoroscopy system within the sterile to produce a two-dimensional image. The two-dimensional image is simultaneously displayed on an operative display within or adjacent the sterile filed and on a display of a remote image processor outside the operative field. The two-dimensional image of the remote display is manually marked or annotated to show anatomical or treatment information which is simultaneously shown on the operative display.
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公开(公告)号：US10035982B2
公开(公告)日：2018-07-31
申请号：US15664988
申请日：2017-07-31
Applicant: BioCardia, Inc.
Inventor： Didier Rouy , Peter A. Atlman , Benjamin Koziner
IPC: C12N5/00 , C12N5/0775 , A61K35/28 , A61K9/00 , A61K35/10 , A61K35/00 , C12Q1/6883 , A61K35/12
CPC classification number: C12N5/0663 , A61K9/0019 , A61K35/00 , A61K35/10 , A61K35/28 , A61K2035/124 , C12N2500/84 , C12N2502/11 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158
Abstract: A method for expanding mesenchymal cells derived from autologous bone marrow in autologous culture medium which can be used in a clinical setting, and a business method for performing such expansions in the future as a service for patients. A method for expanding mesenchymal cells derived from autologous bone marrow in autologous culture medium including a diagnostic kit for the autologous cell therapy to determine whether a patient will respond to the autologous cell therapy for treatment of a disease, in which said kit comprising a system for detecting gene and protein expression comprising at least two isolated DNA molecules wherein each isolated DNA molecule detects expression of a gene that is differentially expressed in the tissue of the patient that is intended to be the source of the autologous cell therapy.
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Patent Agency Ranking
公开(公告)号：US20130331932A1
公开(公告)日：2013-12-12
申请号：US13965800
申请日：2013-08-13
Applicant: BioCardia, Inc.
Inventor： Daniel C. Rosenman , Daniel Kayser , Michael Keleher , Nick Fravala , Richard Cook , Mark Tale , Frank Arko , Simon Stertzer , Peter A. Altman
IPC: A61F2/24
CPC classification number: A61M25/0113 , A61B17/0057 , A61F2/2427 , A61M25/0045 , A61M25/005 , A61M25/0051 , A61M25/0052 , A61M25/01 , A61M25/0136 , A61M25/0138 , A61M25/0141 , A61M25/0147 , A61M25/0152 , A61M2025/0687 , A61M2025/09133 , A61M2210/12
Abstract: Methods for easy, atraumatic access to areas of the vasculature that are otherwise difficult to access, using steerable guide catheters constructed with components that are selected to provide optimal navigability, torque transfer, and push ability for a variety of typical percutaneous access routes. The catheter wall thickness in the deflecting segment of the guide catheter is about 1 French (⅓ mm) or less, and includes a slotted deflection tube, and this construction allows a very tight turning radius which in turn enables guide catheter access to regions of the vasculature that are otherwise inaccessible.
Abstract translation: 使用由可选择的导向导管构成的导向导管，用于容易地，无创地进入否则难以进入的脉管系统区域的方法，以提供针对各种典型经皮通路的优化导航性，扭矩传递和推动能力。 引导导管的偏转部分中的导管壁厚度约为1法国（1/3毫米）或更小，并且包括开槽的偏转管，并且该结构允许非常紧的转动半径，这进而使引导导管进入区域 的血管系统，否则无法进入。
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公开(公告)号：US20030225338A1
公开(公告)日：2003-12-04
申请号：US10458769
申请日：2003-06-10
Applicant: BioCardia, Inc.
Inventor： Peter A. Altman
IPC: A61B005/0402 , A61M025/10
CPC classification number: A61F2/82 , A61B5/046 , A61F2002/821 , A61F2250/0067 , A61L31/022 , A61L31/16 , A61L2300/40 , A61M25/10 , A61M2025/0057 , A61M2025/105 , A61M2025/1086
Abstract: Devices and methods for testing a pulmonary vein to determine whether or not ablation would be effective in terminating atrial fibrillation. The devices and methods include a catheter having an expandable balloon attached to the distal end of the catheter. The balloon has pores on the distal end of the balloon for administering a fluid into the target pulmonary vein. The fluid inhibits the electrical impulses generated by the target pulmonary vein. Once the electrical impulses of the target pulmonary vein have been inhibited it can be determined whether or not the atrial fibrillation continues to occur. If the atrial fibrillation has been eliminated, then ablation or other therapy is appropriate. Thus, the devices and methods limit unnecessary treatment of a pulmonary vein.
Abstract translation: 用于测试肺静脉以确定消融是否有效终止心房颤动的装置和方法。 装置和方法包括具有附接到导管的远端的可扩张气囊的导管。 气囊在气囊的远端具有孔，用于将流体施用到目标肺静脉中。 流体抑制由目标肺静脉产生的电脉冲。 一旦目标肺静脉的电脉冲被抑制，可以确定心房颤动是否继续发生。 如果心房颤动已被消除，则消融或其他治疗是适当的。 因此，装置和方法限制了肺静脉的不必要的治疗。
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公开(公告)号：US20230355652A1
公开(公告)日：2023-11-09
申请号：US18343698
申请日：2023-06-28
Applicant: BioCardia, Inc.
Inventor： Ian McNiece
IPC: A61K31/7105 , A61K35/34
CPC classification number: A61K31/7105 , A61K35/34
Abstract: Cardiac stromal cells produce exosomes containing micro RNAs including: miR1, miR133a, and miR206. These micro RNAs have pivotal roles in development and physiology of muscle tissues including the heart. Exosomes containing these micro RNAs are delivered to result in regeneration of ischemic heart tissue.
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公开(公告)号：US20220305237A1
公开(公告)日：2022-09-29
申请号：US17831189
申请日：2022-06-02
Applicant: BioCardia, Inc.
Inventor： Wai Hsueh , Olin Jay Palmer , Scott Comiso , James B. Ross , Ken Vien , Julio Argentieri , Peter Altman
Abstract: A needle-injection catheter includes a catheter body having a distal end, a proximal end, a stiff proximal portion, a flexible distal portion, and a delivery lumen extending therethrough. In a first embodiment, a straight injection needle extends coaxially from a distal tip of the flexible portion of the catheter body, and a plurality of penetration limiting elements positioned circumferentially about a base of the straight injection needle and configured to fold radially inwardly against a shaft of the needle when constrained in a tubular lumen and to extend radially outwardly when unconstrained. In a second embodiment, a helical needle extends from the distal tip of the flexible portion of the catheter body. The helical needle has at least one helical delivery lumen connected to receive an injectable substance from the delivery lumen of the catheter body.
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公开(公告)号：US11141568B2
公开(公告)日：2021-10-12
申请号：US16113556
申请日：2018-08-27
Applicant: BioCardia, Inc.
Inventor： Wai Hsueh , Ken Vien , James B. Ross
Abstract: A bi-directional steerable catheter adapted for delivery into a patient's vasculature. The pull wires which are used to tension the deflectable segment of the steerable catheter are wound in parallel around the axis of the steerable catheter on opposite sides of the steerable catheter.
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