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公开(公告)号：US20240358893A1
公开(公告)日：2024-10-31
申请号：US18769827
申请日：2024-07-11
Applicant: LYRA THERAPEUTICS, INC.
Inventor： Changcheng You , Quynh Pham , Danny Concagh
IPC: A61L27/34 , A61F2/18 , A61F2/90 , A61K31/58 , A61L27/18 , A61L27/54 , A61L27/56 , A61L27/58 , A61M25/10 , A61M31/00
CPC classification number: A61L27/34 , A61F2/186 , A61F2/90 , A61K31/58 , A61L27/18 , A61L27/54 , A61L27/56 , A61L27/58 , A61M25/10 , A61M31/002 , A61F2210/0004 , A61F2250/0031 , A61F2250/0067 , A61L2300/222 , A61L2300/41 , A61L2300/604 , A61L2300/608 , A61M2025/105 , A61M2210/0681
Abstract: This disclosure describes, inter alia, materials, devices, kits and methods that may be used to treat chronic sinusitis. More specifically, a drug-eluting scaffold is implanted in the middle meatus to treat chronic sinusitis for weeks to months.
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2.发明公开
公开(公告)号：US20240358600A1
公开(公告)日：2024-10-31
申请号：US18556244
申请日：2022-04-19
Applicant: THE JOHNS HOPKINS UNIVERSITY
Inventor： Andrew Demmert , Clifford R Weiss , Christopher Ravi Bailey , Aryaman Gupta
CPC classification number: A61J15/0069 , A61J15/0023 , A61J15/0042 , A61J15/0061 , A61M2025/0047 , A61M25/0097 , A61M2025/0681 , A61M25/10
Abstract: A sleeved gastrojejunostomy (GJ) tube, according to the present invention, includes an inner cannula or feeding cannula that is housed in a sleeve. This arrangement allows the inner cannula to be replaced easily at the bedside by non-specialists. Traditional methods to insert the sleeved GJ tube are utilized, but in the event of feeding cannula damage or clogs, the inner cannula can be easily removed and a new one can be placed, without the need for fluoroscopy or anesthesia. The use of sleeved GJ tubes will expedite patient care, reduce complications, and decrease healthcare costs. The present invention aims to solve the common issue of a clogged GJ Tube. Clogged GJ tubes lead to emergency room visits, hospital admission, and interventional procedures. The present invention would enable exchanges of a clogged feeding cannula by providers or parents without radiation, sedation, or room time.
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公开(公告)号：US20240335459A1
公开(公告)日：2024-10-10
申请号：US18400993
申请日：2023-12-29
Applicant: Topical Sinus Therapeutics, Inc.
Inventor： Russell N. REITZ , John C. Tarrant
IPC: A61K31/58 , A61B17/24 , A61K9/00 , A61K9/06 , A61K9/50 , A61K31/7036 , A61K47/36 , A61K47/38 , A61M1/00 , A61M3/02 , A61M25/10 , A61M31/00
CPC classification number: A61K31/58 , A61B17/24 , A61K9/0043 , A61K9/06 , A61K9/5015 , A61K31/7036 , A61K47/36 , A61K47/38 , A61M3/0262 , A61M31/00 , A61B2017/246 , A61M1/84 , A61M25/10 , A61M2210/0618 , A61M2210/0681
Abstract: A medication or combination of medications for the treatment of a disease involving the sinuses is incorporated into a sterile medical gel. The viscosity of the gel or the adhesion of the gel to the patient's sinus cavity allows the gel to be maintained in the cavity for a sufficient length of time for treatment of the affected area, thereby reducing the amount of wasted medication that would otherwise result from other topical methods. In one embodiment, the medicated gel comprises a sterile viscous gel having a viscosity sufficient to be maintained within a paranasal sinus cavity after insertion, and a medication dispersed in the sterile viscous gel.
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公开(公告)号：US12102341B2
公开(公告)日：2024-10-01
申请号：US17549351
申请日：2021-12-13
Applicant: MIVI Neuroscience, Inc.
Inventor： Matthew F. Ogle
IPC: A61B17/22 , A61M1/00 , A61M25/00 , A61M25/09 , A61M25/10 , A61M27/00 , A61B17/00 , A61B17/221 , A61B17/3207 , A61B90/00
CPC classification number: A61B17/22 , A61M1/00 , A61M1/71 , A61M1/732 , A61M1/84 , A61M25/0068 , A61M25/0074 , A61M27/006 , A61B17/00234 , A61B2017/00331 , A61B2017/22079 , A61B17/221 , A61B2017/2212 , A61B2017/320716 , A61B2090/064 , A61B2217/005 , A61M1/74 , A61M1/85 , A61M25/09 , A61M25/10 , A61M2205/3344 , A61M2210/0693
Abstract: A suction catheter system is described with a suction extension interfaced with a guide catheter to form a continuous suction lumen extending through a portion of the guide catheter and through the suction extension. The suction extension can be positioned by tracking the suction nozzle through a vessel while moving a proximal portion of the suction extension within the lumen of the guide catheter. The suction extension can comprise a connecting section with a non-circular cross section for interfacing with the inner lumen of an engagement section of the guide catheter. The tubular body of the guide catheter can have a reduced diameter distal section the can be useful to restrain the movement of the suction extension. Proximal fittings attached to the guide catheter can facilitate safe removal of the catheter system from the patient by allowing for the removal of some or all of a tubular extension of the suction extension from the guide catheter behind a hemostatic seal. Pressure sensors connected to the proximal fittings can help to guide the procedures with reduced risk of embolizing thrombus.
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公开(公告)号：US12102331B2
公开(公告)日：2024-10-01
申请号：US16779514
申请日：2020-01-31
Applicant: Daniel Ezra Walzman
Inventor： Daniel Ezra Walzman
CPC classification number: A61B17/12186 , A61B17/12109 , A61M25/007 , A61B2017/1205 , A61M2025/0018 , A61M25/0075 , A61M25/10 , A61M2205/0266
Abstract: A device using side holes which creates a plug upstream of the distal-most portion of said micro-catheters and thereby ameliorates the suboptimal outcomes associated with creating a plug upstream of a distal end hole via injecting embolics only at the distal-most portion of said catheters.
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公开(公告)号：US12096938B2
公开(公告)日：2024-09-24
申请号：US18189847
申请日：2023-03-24
Applicant: LimFlow GmbH
Inventor： Rowan Olund Hettel , David Hugo Deaton , Sophie Humbert
CPC classification number: A61B17/11 , A61B17/12036 , A61B17/12109 , A61B17/12136 , A61F2/07 , A61M1/3613 , A61M1/3653 , A61M25/10 , A61B2017/1107 , A61B2017/1139 , A61B2090/3966
Abstract: Devices and methods divert blood flow from a first vessel to a second vessel and maintain blood flow in the first vessel. The device includes a first segment and a second segment. The first segment is configured to anchor in the first vessel. The first segment includes a window to allow blood to flow into the first segment, through the window, and distal in the first vessel. The second segment is configured to anchor in the second vessel. The second segment is configured to allow blood to flow into the first segment, through the second segment, and into the second vessel.
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7.发明公开
公开(公告)号：US20240307172A1
公开(公告)日：2024-09-19
申请号：US18434642
申请日：2024-02-06
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Michael R. Bialas , Kristen Hicks , Michael C. Murad , Gil Senesh , Quang Ngoc Vu , Gonzalo German Angelico , Carla Susana Cerqueira , Victoria Mariko Low , Andrea Fernandez , Jeanette Jasmine Corona Kelly (formerly Corona) , Taylor Michael Winters , Ashley Akemi Ishigo , Brendan Michael Dalbow , Kim D. Nguyen , Lien Huong Thi Hoang
CPC classification number: A61F2/24 , A61B50/30 , A61F2/2418 , A61F2/2436 , A61M25/10 , A61F2/2433 , A61F2/9517 , A61F2002/9583 , A61F2220/0025 , A61F2220/0075 , A61F2230/0002 , A61F2250/0098
Abstract: Methods and systems for rotationally aligning a commissure of a prosthetic heart valve with a commissure of a native valve are disclosed. In some examples, a method can include advancing a distal end portion of an assembly toward a native heart valve, the assembly comprising a delivery apparatus and a prosthetic heart valve, and including one or more radiopaque markers, where one radiopaque marker is suspended within a cell of a frame of the prosthetic heart valve and aligned with a commissure of the prosthetic heart valve. The method further includes receiving a fluoroscopic image in a selected imaging view of the prosthetic heart valve on the delivery apparatus, determining, based on the fluoroscopic image and the one or more radiopaque markers, whether the prosthetic heart valve is in a desired rotational orientation, and rotating the assembly until the prosthetic heart valve is in the desired rotational orientation.
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公开(公告)号：US20240277623A1
公开(公告)日：2024-08-22
申请号：US18631293
申请日：2024-04-10
Applicant: GIE Medical, Inc.
Inventor： Lixiao Wang , Peter Barnett
IPC: A61K9/48 , A61K31/337 , A61K31/436 , A61M25/10 , A61P1/00
CPC classification number: A61K9/4816 , A61K9/4833 , A61K31/337 , A61K31/436 , A61M25/10 , A61M25/1029 , A61P1/00 , A61M2025/1031 , A61M2025/105 , A61M2210/105
Abstract: Various embodiments disclosed relate to polymer-encapsulated drug particles and a drug-releasing coating including the same, as well as drug-coated balloon catheters for treating, preventing, or reducing the recurrence of strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes the polymer-encapsulated drug particles; or a drug-releasing coating including the polymer-encapsulated drug particles; or a therapeutic agent and a first and/or second additive; or a combination thereof.
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公开(公告)号：US20240269439A1
公开(公告)日：2024-08-15
申请号：US18645654
申请日：2024-04-25
Applicant: Urotronic, Inc.
Inventor： Lixiao Wang , Peter Barnett , David Hendrickson
CPC classification number: A61M25/10 , A61L29/16 , A61L2300/416 , A61M2025/105 , A61M2025/1059 , A61M2025/1068 , A61M2210/105 , A61M2210/1057 , A61M2210/106 , A61M2210/1064 , A61M2210/1085 , A61M2210/1089
Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.
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公开(公告)号：US12053590B2
公开(公告)日：2024-08-06
申请号：US17074299
申请日：2020-10-19
Applicant: Silk Road Medical, Inc.
Inventor： David W. Chang
CPC classification number: A61M19/00 , A61B6/487 , A61B18/1492 , A61M5/007 , A61M25/0084 , A61M25/04 , A61M25/10 , A61M25/1011 , A61M2025/009 , A61M2210/12
Abstract: Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure.
