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    POLYPHENOL COATING AND PREPARATION METHOD AND USE THEREOF
    2.
    发明公开
    POLYPHENOL COATING AND PREPARATION METHOD AND USE THEREOF 审中-公开

    公开(公告)号：US20240189480A1

    公开(公告)日：2024-06-13

    申请号：US18295378

    申请日：2023-04-04

    申请人： Anhui Medical University

    发明人： Hua QIU ,  Zhaojia LIANG ,  Quanli LI ,  Zirui CHEN ,  Jialong CHEN ,  Xiangyang LI ,  Shuang TAN

    IPC分类号： A61L27/36

    CPC分类号： A61L27/3637

    摘要： The present disclosure relates to the technical field of coatings. In order to prepare a polyphenol coating more efficiently and gently on the surface of a material, the present disclosure provides a preparation method of a polyphenol coating, including the following steps: (1) preparing a Tanfloc aqueous solution; (2) adjusting the Tanfloc aqueous solution obtained in step (1) to be in a colloidal suspension state to obtain a modified solution; and (3) placing a carrier material in the modified solution prepared in step (2) to obtain a modified coating on a surface of the carrier material. In the present disclosure, by the preparation method of a polyphenol coating, the polyphenol coating can be efficiently prepared on a material surface under mild conditions.

    Beta-glucan-based scaffold for biological tissue engineering using radiation fusion technology, and production method therefor
    6.
    发明授权
    Beta-glucan-based scaffold for biological tissue engineering using radiation fusion technology, and production method therefor 有权
    基于β-葡聚糖的支架用于生物组织工程的辐射融合技术及其生产方法

    公开(公告)号：US08592574B2

    公开(公告)日：2013-11-26

    申请号：US13144851

    申请日：2010-01-22

    申请人： Sung Ki Song ,  Yong Man Jang ,  In Ho Jeon ,  Sang Jin Ko ,  Jeong Rhan Jeon ,  Gie Taek Chun ,  Youn Mook Lim ,  Hui Jeong Kwon

    发明人： Sung Ki Song ,  Yong Man Jang ,  In Ho Jeon ,  Sang Jin Ko ,  Jeong Rhan Jeon ,  Gie Taek Chun ,  Youn Mook Lim ,  Hui Jeong Kwon

    IPC分类号： C07H3/06

    CPC分类号： A61L27/3637 ,  A61L27/20 ,  A61L27/3834 ,  A61L27/56 ,  C08L5/00

    摘要： The present invention relates to a beta-glucan-based scaffold for biological tissue engineering using radiation fusion technology, and to a production method therefor. According to the production method of the present invention for beta-glucan-based scaffold, radiation fusion tissue engineering, a beta-glucan-aqueous solution is cast and is then irradiated in a crosslinking reaction in such a way as to form a gel or solid scaffold, thereby facilitating cell attachment and making it easy to create a biomimetic environment coinductive to the growth and differentiation of stem cells. Consequently, the beta-glucan-based scaffold according to the present invention can be usefully employed as a filler for tissue regeneration, cell culturing and plastic surgery, as a filler for voids in biological tissue, as a scaffold for reconstructive and corrective plastic surgery, and for cell transplantation and drug delivery.

    摘要翻译： 本发明涉及使用辐射融合技术的生物组织工程的β-葡聚糖类支架及其制造方法。 根据本发明的β-葡聚糖类支架的制造方法，放射线融合组织工程，β-葡聚糖水溶液被浇铸，然后在交联反应中照射以形成凝胶或固体 支架，从而促进细胞附着，并且使得容易产生对干细胞生长和分化的诱导环境。 因此，根据本发明的β-葡聚糖类支架可用作组织再生，细胞培养和整形手术的填充剂，作为生物组织中空隙的填充剂，作为重建和矫正性整形手术的支架， 并用于细胞移植和药物递送。

    SOY-PROTEIN CONTAINING POROUS MATERIALS
    7.
    发明申请
    SOY-PROTEIN CONTAINING POROUS MATERIALS 审中-公开
    含多孔材料的大豆蛋白

    公开(公告)号：US20130302896A1

    公开(公告)日：2013-11-14

    申请号：US13798609

    申请日：2013-03-13

    申请人： Northwestern University

    发明人： Ramille N. Shah ,  Karpagavalli Sundaresan ,  Karen B. Chien

    IPC分类号： A61L27/60 ,  C12N5/0775 ,  A61L27/22

    CPC分类号： A61L27/60 ,  A61L27/22 ,  A61L27/3637 ,  A61L27/3834 ,  A61L27/3839 ,  A61L27/56 ,  A61L2430/40

    摘要： Porous soy protein-based materials are provided. Also provided are tissue growth scaffolds comprising the porous soy protein-based materials. Methods for forming the porous soy protein-based materials and methods for growing tissue on the tissue growth scaffolds are also provided. The porous soy protein-based materials comprise a plurality of soy protein chains that are crosslinked in a three-dimensional structure that provides a high degree of porosity. In order to achieve highly porous structures, the soy proteins, which are globular in nature, can be partially denatured in order to facilitate crosslinking between, and entanglement of, the soy protein chains.

    摘要翻译： 提供多孔大豆蛋白质材料。 还提供了包含多孔大豆蛋白质材料的组织生长支架。 还提供了形成多孔大豆蛋白质材料的方法和用于在组织生长支架上生长组织的方法。 基于多孔大豆蛋白的材料包括多个大豆蛋白链，其以提供高孔隙率的三维结构交联。 为了实现高度多孔的结构，本质上球状的大豆蛋白质可以部分变性，以促进大豆蛋白链之间的交联和缠结。

    BETA-GLUCAN-BASED SCAFFOLD FOR BIOLOGICAL TISSUE ENGINEERING USING RADIATION FUSION TECHNOLOGY, AND PRODUCTION METHOD THEREFOR
    8.
    发明申请
    BETA-GLUCAN-BASED SCAFFOLD FOR BIOLOGICAL TISSUE ENGINEERING USING RADIATION FUSION TECHNOLOGY, AND PRODUCTION METHOD THEREFOR 有权
    基于BETA-GLUCAN的生物组织工程利用辐射融合技术及其生产方法

    公开(公告)号：US20110275795A1

    公开(公告)日：2011-11-10

    申请号：US13144851

    申请日：2010-01-22

    申请人： Sung Ki Song ,  Yong Man Jang ,  In Ho Jeon ,  Sang Jin Ko ,  Jeong Rhan Jeon ,  Gie Taek Chun ,  Youn Mook Lim ,  Hui Jeong Kwon

    发明人： Sung Ki Song ,  Yong Man Jang ,  In Ho Jeon ,  Sang Jin Ko ,  Jeong Rhan Jeon ,  Gie Taek Chun ,  Youn Mook Lim ,  Hui Jeong Kwon

    IPC分类号： C07H3/06

    CPC分类号： A61L27/3637 ,  A61L27/20 ,  A61L27/3834 ,  A61L27/56 ,  C08L5/00

    摘要： The present invention relates to a beta-glucan-based scaffold for biological tissue engineering using radiation fusion technology, and to a production method therefor. According to the production method of the present invention for beta-glucan-based scaffold, radiation fusion tissue engineering, a beta-glucan-aqueous solution is cast and is then irradiated in a crosslinking reaction in such a way as to form a gel or solid scaffold, thereby facilitating cell attachment and making it easy to create a biomimetic environment coinductive to the growth and differentiation of stem cells. Consequently, the beta-glucan-based scaffold according to the present invention can be usefully employed as a filler for tissue regeneration, cell culturing and plastic surgery, as a filler for voids in biological tissue, as a scaffold for reconstructive and corrective plastic surgery, and for cell transplantation and drug delivery.

    摘要翻译： 本发明涉及使用辐射融合技术的生物组织工程的β-葡聚糖类支架及其制造方法。 根据本发明的β-葡聚糖类支架的制造方法，放射线融合组织工程，β-葡聚糖水溶液被浇铸，然后在交联反应中照射以形成凝胶或固体 支架，从而促进细胞附着，并且使得容易产生对干细胞生长和分化的诱导环境。 因此，根据本发明的β-葡聚糖类支架可用作组织再生，细胞培养和整形手术的填充剂，作为生物组织中空隙的填充剂，作为重建和矫正性整形手术的支架， 并用于细胞移植和药物递送。

    Use of a polysaccharide excreted by the vibrio diabolicus species in bone repair
    9.
    发明申请
    Use of a polysaccharide excreted by the vibrio diabolicus species in bone repair 有权
    使用由维管弧菌物种排泄的多糖在骨修复中的应用

    公开(公告)号：US20040030403A1

    公开(公告)日：2004-02-12

    申请号：US10312886

    申请日：2003-08-05

    发明人： Jean Guezennec ,  Philippe Zanchetta

    IPC分类号： A61F002/28

    CPC分类号： A61L27/54 ,  A61L27/20 ,  A61L27/34 ,  A61L27/3637 ,  A61L2300/232 ,  A61L2300/412 ,  A61L2430/02

    摘要： The invention concerns the use of a polysaccharide excreted by the Vibrio diabolicus species for making a medicine with cicatrising activity, in particular bone repair activity. The invention also concerns a bone reconstruction biomaterial comprising said polysaccharide and a bone endoprosthesis whereof the surface is coated with such a polysaccharide.

    摘要翻译： 本发明涉及由弧菌弧菌物种排泄的多糖用于制备具有c ing活动的药物，特别是骨修复活性。 本发明还涉及包含所述多糖和骨内用假体的骨重建生物材料，其中表面被这种多糖包被。