公开(公告)号：US20240141537A1

公开(公告)日：2024-05-02

申请号：US18014148

申请日：2022-11-08

申请人： Anhui Medical University

发明人： Shunli ZHENG ,  Qin RAO ,  Ling WENG ,  Jinshuang ZHANG ,  Donghao LIU ,  Quanli LI ,  Ying CAO ,  Jialong CHEN ,  Xiangyang LI ,  Hua QIU ,  Shengzhuo ZHANG ,  Daojun SHEN

IPC分类号： C25D11/26

CPC分类号： C25D11/26

摘要： The present disclosure provides a superhydrophobic and self-cleaning anticoagulant composite coating material and a preparation method and use thereof, and relates to the technical field of biomedical materials. In the coating material provided by the present disclosure, a titanium dioxide nanotube-based structure increases microscopic roughness of a surface of a titanium-based metal substrate, and a hydrophobic modification layer reduces surface energy of the material. The rough structure and the hydrophobic modification layer have a synergistic effect to construct a superhydrophobic surface, making the surface of the material have self-cleaning characteristics and low adhesion. Air can be retained on the surface of the material to form an air layer, thereby reducing the contact area between the material and bacteria and platelets in the blood, and inhibiting adhesion of the bacteria, platelets, and plasma proteins to the material.

公开(公告)号：US20240189480A1

公开(公告)日：2024-06-13

申请号：US18295378

申请日：2023-04-04

申请人： Anhui Medical University

发明人： Hua QIU ,  Zhaojia LIANG ,  Quanli LI ,  Zirui CHEN ,  Jialong CHEN ,  Xiangyang LI ,  Shuang TAN

IPC分类号： A61L27/36

CPC分类号： A61L27/3637

摘要： The present disclosure relates to the technical field of coatings. In order to prepare a polyphenol coating more efficiently and gently on the surface of a material, the present disclosure provides a preparation method of a polyphenol coating, including the following steps: (1) preparing a Tanfloc aqueous solution; (2) adjusting the Tanfloc aqueous solution obtained in step (1) to be in a colloidal suspension state to obtain a modified solution; and (3) placing a carrier material in the modified solution prepared in step (2) to obtain a modified coating on a surface of the carrier material. In the present disclosure, by the preparation method of a polyphenol coating, the polyphenol coating can be efficiently prepared on a material surface under mild conditions.