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1.
公开(公告)号:US20240399024A1
公开(公告)日:2024-12-05
申请号:US18572312
申请日:2022-06-21
Applicant: BIO-CHANGE LTD.
Inventor: Ishay ATTAR , Sinik KEREN , Shani COHEN
Abstract: Embodiments of the present disclosure relate to particles. compositions. tissue scaffolds. apparatuses. and uses and methods thereof for body contouring. tissue engineering, regenerative medicine, aesthetic dermatology, and reconstructive procedures or surgery.
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公开(公告)号:US20240398546A1
公开(公告)日:2024-12-05
申请号:US18678297
申请日:2024-05-30
Applicant: RxSight, Inc.
Inventor: Ilya Goldshleger , John Kondis , Victoria Piunova , Christian Sandstedt
Abstract: Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.
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公开(公告)号:US20240374788A1
公开(公告)日:2024-11-14
申请号:US18604284
申请日:2024-03-13
Applicant: Mark A. Anton
Inventor: Mark A. Anton
Abstract: Methods, systems, apparatuses and devices for implantation in a soft-tissue biological environment that include a primary layer for containing a filler substance, an interface and a secondary layer, including embodiments where the secondary layer an ePTFE layer, the primary layer is a silicone layer, the interface is mechanical or adhesive and the filler substance can include particulates and lattices.
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公开(公告)号:US12115275B2
公开(公告)日:2024-10-15
申请号:US17179971
申请日:2021-02-19
Applicant: Boston Scientific Scimed, Inc.
Inventor: Joseph Thomas Delaney, Jr. , Patrick Willoughby , David Robert Wulfman , Andrew J. Ro , Niraj Gurung
CPC classification number: A61L27/16 , A61L27/48 , C08J3/246 , C08L53/00 , D01D5/0023 , D01D5/003 , D01D5/0985 , A61L2430/20 , C08J2323/18 , C08J2323/22 , C08J2337/00 , C08J2479/02 , C08L2203/02 , D10B2509/06 , A61L27/48 , C08L23/22
Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.
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公开(公告)号:US12070384B2
公开(公告)日:2024-08-27
申请号:US18079345
申请日:2022-12-12
Applicant: CONMED Corporation
Inventor: Kevin A. Rocco , Bhavana Mohanraj , Jeffrey Ott , Justin Bendigo , Jacob Edward Komenda , Mark Theodore Aronson , Andrew James Carter
IPC: A61F2/08 , A61F2/00 , A61L27/14 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/48 , A61L27/52 , A61L27/56 , A61L27/58 , D06N3/00 , A61L27/34 , A61L27/50 , D04B21/12
CPC classification number: A61F2/08 , A61F2/0063 , A61L27/14 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/48 , A61L27/52 , A61L27/56 , A61L27/58 , D06N3/0043 , A61F2002/0068 , A61F2002/0081 , A61F2210/0004 , A61F2210/0057 , A61F2210/0061 , A61F2210/0076 , A61F2240/001 , A61L27/34 , A61L27/50 , A61L2430/10 , D04B21/12 , D10B2509/08 , Y10T428/249921 , Y10T428/249978 , Y10T442/2484 , Y10T442/419
Abstract: A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.
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6.
公开(公告)号:US20240277904A1
公开(公告)日:2024-08-22
申请号:US18681556
申请日:2022-08-05
Applicant: NOVOCHIZOL SA
Inventor: VLADISLAV FOMENKO , YURIY KARGAPOLOV , ALEXEY KHARCHENKO , DAVID SERGEEVICHEV
CPC classification number: A61L27/52 , A61L27/26 , A61L27/48 , A61L27/56 , B33Y70/00 , C08J9/0061 , C08L5/08 , C12N5/0062 , C08J2405/08 , C12N2533/72 , C12N2537/10
Abstract: The present invention is directed to gels, cryogels and other polymer scaffolds, solid surfaces, aggregates, films and coatings comprising a soluble chemically modified cross-linked chitosan useful for 3D cell and organoid bioprinting and other uses in biology, medicine, bioanalytics and environmental sciences and methods of preparation thereof.
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公开(公告)号:US12064533B2
公开(公告)日:2024-08-20
申请号:US18324951
申请日:2023-05-26
Applicant: Duke University
Inventor: Benjamin J. Wiley , Huayu Tong , Jiacheng Zhao
CPC classification number: A61L27/48 , A61F2/30756 , A61F2/3094 , A61L27/52 , A61F2002/30024 , A61F2002/30471 , A61F2002/30761 , A61L2400/12 , A61L2430/06
Abstract: Cellulose-reinforced hydrogels may include a cellulose nanofiber network and an interstitial hydrogel portion within interstitial regions of the cellulose nanofiber network, the interstitial hydrogel portion comprising polyvinyl alcohol (PVA), wherein the hydrogel component has a crystallinity of 20% or greater.
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公开(公告)号:US12059509B1
公开(公告)日:2024-08-13
申请号:US16866966
申请日:2020-05-05
Applicant: Integra LifeSciences Corporation
Inventor: Kenneth Burhop , Sunil Saini , Ankur Gandhi , Angana Kharge , Brandon Johnson , Paul Bonvallet
CPC classification number: A61L27/60 , A61F2/105 , A61L27/362 , A61L27/48 , A61L27/56 , A61L27/58 , A61F2210/0004
Abstract: Disclosed is a method of regenerating a skin wound using a perforated dermal regeneration matrix combined with autograft in a single-stage procedure. The size of the perforations and the spacing between perforations in the dermal matrix are selected to facilitate drainage, encourage vessel growth and minimize scar tissue formation.
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公开(公告)号:US11986384B2
公开(公告)日:2024-05-21
申请号:US16923782
申请日:2020-07-08
Applicant: Biorez, Inc.
Inventor: Kevin A. Rocco , Bhavana Mohanraj , Jeffrey Ott , Justin Bendigo , Jacob Edward Komenda , Mark Theodore Aronson , Andrew James Carter
IPC: A61F2/08 , A61F2/00 , A61L27/14 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/48 , A61L27/52 , A61L27/56 , A61L27/58 , D06N3/00 , A61L27/34 , A61L27/50 , D04B21/12
CPC classification number: A61F2/08 , A61F2/0063 , A61L27/14 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/48 , A61L27/52 , A61L27/56 , A61L27/58 , D06N3/0043 , A61F2002/0068 , A61F2002/0081 , A61F2210/0004 , A61F2210/0057 , A61F2210/0061 , A61F2210/0076 , A61F2240/001 , A61L27/34 , A61L27/50 , A61L2430/10 , D04B21/12 , D10B2509/08 , Y10T428/249921 , Y10T428/249978 , Y10T442/2484 , Y10T442/419
Abstract: A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.
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公开(公告)号:US20240156604A1
公开(公告)日:2024-05-16
申请号:US18507460
申请日:2023-11-13
Applicant: Arthrex, Inc.
Inventor: Patrick A. Smith , Reinhold Schmieding , Andrew Osika
CPC classification number: A61F2/30756 , A61L27/18 , A61L27/34 , A61L27/48 , A61L27/56 , A61F2002/0068 , A61F2002/30131
Abstract: The present disclosure provides a prosthetic device for replacing or augmenting a damaged meniscus.
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