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    HARVESTING BONE GRAFT MATERIAL FOR USE IN SPINAL AND OTHER BONE FUSION SURGERIES
    3.
    发明申请
    HARVESTING BONE GRAFT MATERIAL FOR USE IN SPINAL AND OTHER BONE FUSION SURGERIES 审中-公开
    用于脊柱和其他骨融合手术的骨折材料

    公开(公告)号：US20160113780A1

    公开(公告)日：2016-04-28

    申请号：US14688544

    申请日：2015-04-16

    Applicant: Seth L. Neubardt

    Inventor： Seth L. Neubardt

    IPC: A61F2/44 ,  A61B17/32 ,  A61B17/16

    CPC classification number: A61F2/4601 ,  A61B17/1635 ,  A61B17/1671 ,  A61B17/320068 ,  A61B2017/320072 ,  A61F2/442 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2/4644 ,  A61F2002/30471 ,  A61F2002/30845 ,  A61F2002/445 ,  A61F2002/4648 ,  A61F2002/4649

    Abstract: A system for harvesting bone graft material for use during bone fusion surgery. In one embodiment, a bone cutting tool has a blade fixed on a distal end of a shaft. The distal end of the shaft is pivoted on a cage set between two bones to be fused, and the blade is activated to cut into the bones and form a solid bone segment in each bone as the tool shaft turns. A paddle is arranged to be inserted between the bones, and to displace the cut bone segments so that a leading portion of each segment enters the bone opposite the bone from which the segment was cut, a central portion of the segment spans across the bones, and a trailing portion of the segment remains in the bone from which it was cut. The displaced segments act as strut grafts to fuse the bones to one another.

    Abstract translation: 骨融合手术期间采集骨移植材料的系统。 在一个实施例中，骨切割工具具有固定在轴的远端上的刀片。 轴的远端在两个骨头之间的笼子上枢转以被熔化，并且刀片被激活以切割成骨骼，并且随着工具轴转动而在每个骨中形成固体骨段。 桨被布置成插入骨头之间，并且移动切割的骨段，使得每个段的前导部分进入与骨骼切割的骨相对的骨，该段的中心部分跨越骨骼， 并且该段的尾部保留在被切割的骨中。 移位的部分作为支柱移植物将骨骼彼此融合。

    Intervertebral disc
    6.
    发明授权
    Intervertebral disc 失效
    椎间盘

    公开(公告)号：US08163554B2

    公开(公告)日：2012-04-24

    申请号：US11858716

    申请日：2007-09-20

    Applicant: Rita Kandel

    Inventor： Rita Kandel

    IPC: C12N5/077

    CPC classification number: A61L27/3856 ,  A61F2/28 ,  A61F2002/30678 ,  A61F2002/4435 ,  A61F2002/4445 ,  A61F2002/445 ,  A61F2310/00359 ,  A61L27/3612 ,  A61L27/3633 ,  A61L27/3817 ,  A61L2430/38

    Abstract: The present invention relates to an engineered biological material comprising or enriched for tissue of intervertebral disc; tissue derived from an engineered biological material; constructs comprising one or more tissues from an engineered biological material; methods for producing the engineered biological materials and constructs; and methods of using the engineered biological materials and constructs.

    Abstract translation: 本发明涉及包含或富集椎间盘组织的工程生物材料; 衍生自工程生物材料的组织; 包含来自工程生物材料的一种或多种组织的构建体; 用于生产工程生物材料和构建体的方法; 以及使用工程化生物材料和构建体的方法。

    In situ bioprosthetic filler and method, particularly for the in situ formation of vertebral disc bioprosthetics
    8.
    发明授权
    In situ bioprosthetic filler and method, particularly for the in situ formation of vertebral disc bioprosthetics 有权
    原位生物假体填充剂和方法，特别是用于原位形成椎间盘生物假体

    公开(公告)号：US07896920B2

    公开(公告)日：2011-03-01

    申请号：US11932066

    申请日：2007-10-31

    Applicant: K. Umit Yuksel ,  Steven P. Walsh ,  Kirby S. Black

    Inventor： K. Umit Yuksel ,  Steven P. Walsh ,  Kirby S. Black

    IPC: A61F2/44 ,  A61B17/68

    CPC classification number: A61L27/3691 ,  A61F2002/4445 ,  A61F2002/445 ,  A61L27/18 ,  A61L27/22 ,  A61L27/227 ,  A61L27/3604 ,  A61L27/3658 ,  A61L27/40 ,  C08L71/02

    Abstract: Bioprosthetic devices include an exterior biological tissue member which at least partly defines a cavity, and a proteinaceous biopolymer which fills the cavity, and intercalates and is chemically bound (fixed) to the tissue of the surrounding biological tissue member. In preferred forms, the bioprosthetic device is a bioprosthetic vertebral disc having a fibrillar outer annulus which surrounds and defines an interior cavity and is formed by removal of at least a substantial portion of the natural gelatinous core therefrom. The cavity defined by the fibrillar outer annulus may then be filled with a flowable proteinaceous biopolymer. Preferably, the proteinaceous biopolymer is a liquid mixture comprised of human or animal-derived protein material and a di- or polyaldehyde, which are allowed to react in situ to form a cross-linked biopolymer within the cavity. The liquid mixture may be formed in advance of being introduced into the cavity, or may be formed simultaneously during introduction into the cavity.

    Abstract translation: 生物假体装置包括至少部分地限定空腔的外部生物组织构件和填充空腔并插入并化学结合（固定）到周围生物组织构件的组织的蛋白质生物聚合物。 在优选形式中，生物假体装置是具有纤维外环的生物假体椎间盘，其围绕并限定内腔，并且通过从其中去除至少大部分天然胶状核而形成。 然后可以用可流动的蛋白质生物聚合物填充由纤维状外环形成的空腔。 优选地，蛋白质生物聚合物是由人或动物衍生的蛋白质材料和二醛或多醛组成的液体混合物，其允许在原位反应以在腔内形成交联的生物聚合物。 液体混合物可以在引入空腔之前形成，或者可以在引入空腔期间同时形成。

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