-
公开(公告)号：US20130064827A1
公开(公告)日：2013-03-14
申请号：US13593362
申请日：2012-08-23
申请人： Jian Chen , Ellen Filvaroff , Sherman Fong , Dorothy French , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gumey , Kenneth J. Hillan , Sarah G. Hymowitz , Hanzhong Li , James Pan , Melissa A. Starovasnik , Daniel Tumas , Menno Van Lookeren , Richard Vandlen , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Daniel G. Yansura
发明人： Jian Chen , Ellen Filvaroff , Sherman Fong , Dorothy French , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gumey , Kenneth J. Hillan , Sarah G. Hymowitz , Hanzhong Li , James Pan , Melissa A. Starovasnik , Daniel Tumas , Menno Van Lookeren , Richard Vandlen , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Daniel G. Yansura
IPC分类号： A61K39/395 , C07K16/24 , C07H21/02 , A61P19/04 , A61P29/00 , C07H21/04 , A61K31/7088
CPC分类号： C07K16/244 , A61K38/00 , C07H21/04 , C07K14/54 , C07K14/7155 , C07K2317/21 , C07K2317/24 , C07K2317/35 , C07K2317/54 , C07K2317/55 , C07K2317/62 , G01N33/505 , G01N33/564 , G01N33/574 , G01N33/57407 , G01N33/57423 , G01N33/57438 , G01N33/57492 , G01N2333/54 , G01N2333/7155
摘要： The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
摘要翻译： 本发明涉及与IL-17，IL-17受体和编码那些多肽的核酸分子具有序列同一性的新型多肽。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本文还提供了治疗退行性软骨疾病和其它炎性疾病的方法。
-
公开(公告)号：US20110243930A1
公开(公告)日：2011-10-06
申请号：US13025008
申请日：2011-02-10
申请人： SARAH C. BODARY-WINTER , Hilary Clark , Brisdell Hunte , Janet K. Jackman , Jill R. Schoenfeld , P. Mickey Williams , William I. Wood , Thomas D. Wu
发明人： SARAH C. BODARY-WINTER , Hilary Clark , Brisdell Hunte , Janet K. Jackman , Jill R. Schoenfeld , P. Mickey Williams , William I. Wood , Thomas D. Wu
IPC分类号： A61K39/395 , C12Q1/68 , C40B30/00 , G01N33/68 , A61K38/17 , A61P19/02 , A61P31/12 , A61P31/14 , A61P31/20 , A61P31/22 , A61P31/04 , A61P31/10 , A61P33/00 , A61P33/02 , A61P17/06 , A61P11/06 , A61P37/08 , A61P29/00 , A61P3/10 , A61P37/04 , A61P37/06 , A61P7/06
CPC分类号： C12Q1/6883 , C07K14/47 , C12Q2600/158
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
-
73.发明申请公开(公告)号：US20110142841A1
公开(公告)日：2011-06-16
申请号：US12589398
申请日：2009-10-22
申请人： Alexander Abbas , Sarah C. Bodary , Hilary Clark , Jill R. Schoenfeld , P. Mickey Williams , William I. Wood , Thomas D. Wu
发明人： Alexander Abbas , Sarah C. Bodary , Hilary Clark , Jill R. Schoenfeld , P. Mickey Williams , William I. Wood , Thomas D. Wu
IPC分类号： A61K39/395 , C07H21/04 , C12N15/63 , C12N5/10 , C12P21/00 , C07K14/00 , C07K16/00 , G01N33/53 , A61K39/00 , A61P37/06
CPC分类号： C07K14/435 , A61K38/00
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
-
公开(公告)号：US07951546B2
公开(公告)日：2011-05-31
申请号：US12156180
申请日：2008-05-29
申请人： Gretchen Frantz , Kenneth J. Hillan , Heidi Phillips , Paul Polakis , Susan D. Spencer , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
发明人： Gretchen Frantz , Kenneth J. Hillan , Heidi Phillips , Paul Polakis , Susan D. Spencer , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
IPC分类号： G01N33/53
CPC分类号： C07K14/4748 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505 , C07K14/705 , C07K14/71 , C07K16/18 , C07K16/30 , G01N33/574
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
-
公开(公告)号：US07803915B2
公开(公告)日：2010-09-28
申请号：US10936626
申请日：2004-09-08
申请人： Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang , Chie Sakanaka , Anan Chuntharapai , Chae Janeka Reed
发明人： Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang , Chie Sakanaka , Anan Chuntharapai , Chae Janeka Reed
IPC分类号： C07K16/00 , C12P21/08 , A61K39/395 , C12P21/04
CPC分类号： G01N33/57484 , A61K47/60 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6839 , A61K47/6851 , A61K47/6859 , A61K51/1006 , A61K51/1018 , A61K2039/505 , C07K16/1072 , C07K16/18 , C07K16/30 , C07K16/303 , C07K2317/73 , C07K2317/76 , C07K2317/77
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译： 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物，以及使用这些物质组合物的方法。
-
公开(公告)号：US07749504B2
公开(公告)日：2010-07-06
申请号：US11733861
申请日：2007-04-11
申请人： Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
发明人： Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
IPC分类号： A61K39/395 , C12P21/04 , C12P21/08 , C07K16/00
CPC分类号： G01N33/57484 , A61K47/60 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6839 , A61K47/6851 , A61K47/6859 , A61K51/1006 , A61K51/1018 , A61K2039/505 , C07K16/1072 , C07K16/18 , C07K16/30 , C07K16/303 , C07K2317/73 , C07K2317/76 , C07K2317/77
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译： 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物，以及使用这些物质组合物的方法。
-
77.发明申请公开(公告)号：US20100034817A1
公开(公告)日：2010-02-11
申请号：US12574818
申请日：2009-10-07
申请人： Alexander Abbas , Hilary Clark , Wenjun Ouyang , P. Mickey Williams , William I. Wood , Thomas D. Wu
发明人： Alexander Abbas , Hilary Clark , Wenjun Ouyang , P. Mickey Williams , William I. Wood , Thomas D. Wu
IPC分类号： A61K39/395 , C12Q1/68 , A61P37/04 , A61P37/06
CPC分类号： C12Q1/6837 , C07K14/47 , C12N9/2417 , C12Y302/01001 , G01N33/53 , G01N33/564 , G01N33/6893 , G01N2800/24
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
-
公开(公告)号：US20090324490A1
公开(公告)日：2009-12-31
申请号：US12380124
申请日：2009-02-23
申请人： Belinda Caims , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
发明人： Belinda Caims , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
IPC分类号： A61K51/10 , A61K39/395 , A61K39/00 , A61P35/00
CPC分类号： C07K16/18 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505 , C07K16/30 , C07K16/3023 , C07K16/40 , C07K2317/73 , G01N33/57407
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
-
公开(公告)号：US20090318340A1
公开(公告)日：2009-12-24
申请号：US11976812
申请日：2007-10-29
申请人： Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul Godowski , Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Daniel Tumas , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
发明人： Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul Godowski , Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Daniel Tumas , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
IPC分类号： A61K38/17 , C07K14/435 , C07K16/00
CPC分类号： C07K14/705 , A61K38/00 , C07K14/54 , G01N33/57415 , G01N33/57419 , G01N33/57423 , G01N2500/04
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
-
公开(公告)号：US20090246129A1
公开(公告)日：2009-10-01
申请号：US12323000
申请日：2009-02-09
申请人： Belinda Caims , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillps , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
发明人： Belinda Caims , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillps , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
IPC分类号： A61K51/10 , C12N5/02 , C12N9/96 , A61K39/395 , A61K39/00
CPC分类号： C07K16/18 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505 , C07K16/30 , C07K16/3023 , C07K16/40 , C07K2317/73 , G01N33/57407
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
-
-
-
-
-
-
-
-
-
搜索结果
98 条记录 (耗时 0.08 秒)
