-
公开(公告)号：US20240131218A1
公开(公告)日：2024-04-25
申请号：US18401983
申请日：2024-01-02
申请人： NFS IP Holdings, LLC
发明人： Jed K. JOHNSON , Ross KAYUHA
IPC分类号： A61L17/00 , A61B17/12 , A61F2/04 , A61L27/38 , A61L27/54 , A61L27/56 , D01D5/00 , D01D11/00 , D04C1/02 , D04C1/12
CPC分类号： A61L17/005 , A61B17/12022 , A61B17/12186 , A61F2/04 , A61L27/3834 , A61L27/54 , A61L27/56 , D01D5/0023 , D01D11/00 , D04C1/02 , D04C1/12 , A61B2017/00526 , A61L2400/12 , D01D5/0007
摘要： A composition comprising a plurality of electrospun fiber fragments comprising at least one polymer, a plurality of electrospun fiber fragment clusters comprising at least one polymer, and, optionally, a carrier medium, is disclosed. Also disclosed is a kit comprising a first component of a plurality of electrospun fiber fragments, and a second component of a carrier medium. Also disclosed is a composition comprising a plurality of micronized electrospun fiber fragments, a carrier medium, and, optionally, a plurality of cells. Also disclosed is a biocompatible textile comprising a plurality of micronized electrospun fiber fragments. Also disclosed is a biocompatible suture comprising at least one electrospun fiber. Also disclosed is a method for making a biocompatible suture, comprising electrospinning a polymer solution onto a receiving surface, forming one or more non-overlapping nanofiber threads, removing the nanofiber threads from the receiving surface, and cutting the nanofiber threads into one or more biocompatible sutures.
-
公开(公告)号：US20240123115A1
公开(公告)日：2024-04-18
申请号：US18395521
申请日：2023-12-23
申请人： 206 ORTHO, INC.
IPC分类号： A61L27/18 , A61K9/00 , A61K47/34 , A61L27/16 , A61L27/26 , A61L27/44 , A61L27/46 , A61L27/48 , A61L27/52 , A61L27/54 , A61L27/56 , A61L27/58
CPC分类号： A61L27/18 , A61K9/0024 , A61K47/34 , A61L27/16 , A61L27/26 , A61L27/446 , A61L27/46 , A61L27/48 , A61L27/52 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/406 , A61L2300/604 , A61L2400/06 , A61L2430/02
摘要： A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.
-
公开(公告)号：US20240115766A1
公开(公告)日：2024-04-11
申请号：US18377546
申请日：2023-10-06
CPC分类号： A61L27/306 , A61F2/38 , A61L27/045 , A61L27/06 , A61L27/427 , A61L27/54 , A61L27/56 , A61F2310/00023 , A61F2310/00029 , A61F2310/00059 , A61F2310/00598 , A61L2300/404 , A61L2400/12
摘要： An orthopaedic implant having a bone-engaging layer configured to contact bone and provide antimicrobial properties and methods for making the same.
-
公开(公告)号：US11955321B2
公开(公告)日：2024-04-09
申请号：US17227934
申请日：2021-04-12
申请人： NOVA PLASMA LTD.
发明人： Amnon Lam , Aviad Harhol , Eliezer Fuchs , Chen Porat
CPC分类号： H01J37/32798 , A61L27/18 , A61L27/50 , A61L27/54 , H01J37/321 , H01J37/32403 , H01J37/32449 , H01J37/32568 , H01J37/32715 , H01J37/32733 , H01J37/32825 , A61L2300/406 , A61L2400/18 , A61L2430/04 , H01J37/32091 , H01J37/32348 , A61L27/18 , C08L83/04
摘要： An apparatus for plasma treatment of an implant prior to installing the implant in a live subject is provided. The apparatus comprises an activation device and a portable container detachable from the activation device. The portable container comprises a closed compartment containing the implant immersed in a fluid, and the activation device comprises a slot configured to receive the portable container. The activation device further comprises an electrical circuit configured to be electrically associated with at least one electrode and configured to provide to the at least one electrode electric power suitable for applying a plasma generating electric field in the closed compartment, when the portable container is disposed in the slot. A container suitable for providing plasma treatment to a silicone implant and a method for preparing an implant for implantation surgery are also provided.
-
公开(公告)号：US11952439B2
公开(公告)日：2024-04-09
申请号：US16911831
申请日：2020-06-25
发明人： Zongtao Zhang
IPC分类号： C08F110/02 , A61K31/355 , A61L27/16 , A61L27/54
CPC分类号： C08F110/02 , A61K31/355 , A61L27/16 , A61L27/54 , A61L2430/24 , C08F2500/01 , C08F2810/20
摘要： The invention relates to a surface gradient cross-linked method of a ultra-high molecular weight polyethylene and the application thereof. The surface gradient crosslinked method of ultrahigh molecular weight polyethylene includes a n ultra-high molecular weight polyethylene surface photoinitiator diffusion step and an ultraviolet light irradiation crosslinking step. In this method, the photoinitiator is diffused deeply into the surface of ultra-high molecular weight polyethylene, the body material shows a gradient cross-linking from the surface to the inside after ultraviolet irradiation so that the whole bulk has a high toughness and the surface there of has a high wear resistance.
-
公开(公告)号：US20240108790A1
公开(公告)日：2024-04-04
申请号：US18142503
申请日：2023-05-02
发明人： Adam Feinberg , Thomas Hinton
IPC分类号： A61L27/54 , A61L27/04 , A61L27/10 , A61L27/14 , A61L27/18 , A61L27/20 , A61L27/22 , A61L27/24 , A61L27/38 , A61L27/52 , B29C64/112 , B29C64/118 , B29C64/40 , B33Y10/00 , B33Y70/00
CPC分类号： A61L27/54 , A61L27/04 , A61L27/10 , A61L27/14 , A61L27/18 , A61L27/20 , A61L27/22 , A61L27/222 , A61L27/225 , A61L27/227 , A61L27/24 , A61L27/38 , A61L27/52 , B29C64/112 , B29C64/118 , B29C64/40 , B33Y10/00 , B33Y70/00 , B29K2005/00 , B29K2089/00 , B29L2031/7532
摘要： In one aspect, a method includes providing support material within which the structure is fabricated, depositing, into the support material, structure material to form the fabricated structure, and removing the support material to release the fabricated structure from the support material. The provided support material is stationary at an applied stress level below a threshold stress level and flows at an applied stress level at or above the threshold stress level during fabrication of the structure. The provided support material is configured to mechanically support at least a portion of the structure and to prevent deformation of the structure during the fabrication of the structure. The deposited structure material is suspended in the support material at a location where the structure material is deposited. The structure material comprises a fluid that transitions to a solid or semi-solid state after deposition of the structure material.
-
公开(公告)号：US11944723B2
公开(公告)日：2024-04-02
申请号：US16980247
申请日：2019-03-13
IPC分类号： A61F2/06 , A61F2/00 , A61L27/18 , A61L27/26 , A61L27/34 , A61L27/36 , A61L27/50 , A61L27/54 , A61L27/58
CPC分类号： A61L27/507 , A61F2/0095 , A61F2/06 , A61L27/18 , A61L27/26 , A61L27/34 , A61L27/3633 , A61L27/54 , A61L27/58 , A61F2220/0016 , A61L2300/418 , A61L2420/02
摘要： A vascular repair patch with a polymeric substrate having first and second major surfaces, and at least first and second polymer filament layers, wherein the polymer filaments of the first polymer filament layer are oriented in parallel and the polymer filaments of the second polymer filament layer are oriented randomly. The patch may further include thrombogenic agents and/or extracellular matrix compounds to promote vascular tissue regeneration at the repair site. Further, included are methods of making and using the patch.
-
公开(公告)号：US11944719B2
公开(公告)日：2024-04-02
申请号：US16470548
申请日：2017-12-18
申请人： IVIVA Medical, Inc.
发明人： Charles C. Klassen
CPC分类号： A61L27/3808 , A61L27/18 , A61L27/3813 , A61L27/40 , A61L27/52 , A61L27/54 , A61L27/56
摘要： Disclosed are compositions and methods of making basement membrane constructs having interior or luminal volumes. The interior or luminal volumes may be in the form of vascular networks for liquid (e.g., blood) or gas perfusion. The interior spaces may also contain cells, such as epithelial cells. Also disclosed are tissues and organs, and methods of making thereof, comprising basement membrane constructs.
-
59.发明公开公开(公告)号：US20240100118A1
公开(公告)日：2024-03-28
申请号：US18452724
申请日：2023-08-21
IPC分类号： A61K38/01 , A61K9/00 , A61K38/39 , A61K45/06 , A61L17/08 , A61L27/10 , A61L27/24 , A61L27/54 , A61L29/04 , A61L29/08 , A61L29/16 , A61L31/04 , A61L31/10 , A61L31/16 , C07K14/78
CPC分类号： A61K38/014 , A61K9/0014 , A61K38/39 , A61K45/06 , A61L17/08 , A61L27/10 , A61L27/24 , A61L27/54 , A61L29/045 , A61L29/085 , A61L29/16 , A61L31/044 , A61L31/10 , A61L31/16 , C07K14/78 , A61P17/00
摘要： The present invention is in the fields of medicinal chemistry, biotechnology and pharmaceuticals. The invention provides compositions comprising one or more collagen mimetic peptides, optionally attached to one or more therapeutic compounds or one or more imaging compounds, for use in methods of treating, preventing, ameliorating, curing and diagnosing certain diseases and physical disorders in humans and veterinary animals, as well as methods of manufacturing such composition. The invention also provides medical devices comprising one or more such compositions of the invention. The invention also provides methods of use of such compositions and devices in treating and diagnosing certain diseases and physical disorders in humans and veterinary animals, including ocular diseases or disorders, skin diseases or disorders, certain cancers, particularly intraluminal cancers, gastrointestinal diseases or disorders, genitourinary tract diseases or disorders, fibrotic diseases/disorders and rheumatic diseases/disorders.
-
公开(公告)号：US11938250B2
公开(公告)日：2024-03-26
申请号：US16272808
申请日：2019-02-11
申请人： Surmodics, Inc.
发明人： David E. Babcock , Sean Lundquist , Gary Opperman , Adriyn Torguson , Tim Jentz
IPC分类号： A61L29/08 , A61K31/7024 , A61L15/44 , A61L27/34 , A61L27/54 , A61L29/06 , A61L29/16 , A61L31/10 , A61L31/16 , G01N33/543
CPC分类号： A61L29/085 , A61K31/7024 , A61L15/44 , A61L27/34 , A61L27/54 , A61L29/06 , A61L29/16 , A61L31/10 , A61L31/16 , G01N33/54393 , A61L2300/216 , A61L2300/418 , A61L2300/42 , A61L2400/04 , A61L2400/18 , A61L2420/02 , A61L2420/08
摘要： Embodiments of the disclosure include coatings comprising an oligomerized polyphenol layer. The oligomerized polyphenol layer can be used as an intermediate coated layer on a medical device that hydrogen bonds to a synthetic or natural polymer, which in turn can be used as a top coat or further associated with another coated layer. The multilayered coatings can provide properties such as hemocompatibility or lubricity. In other embodiments, the oligomerized polyphenol layer is used on a medical device as a hemostatic layer configured to contact blood and promote coagulation. The oligomerized polyphenol layer can also be used on the inner surface (e.g., inner diameter) of a medical device to prevent bacterial adherence. The oligomerized polyphenol layer can also be used on the surface of a in vitro diagnostic article, or a cell culture device to, promote adsorption of a biological molecule.
-
-
-
-
-
-
-
-
-
搜索结果
6623 条记录 (耗时 0.046 秒)
