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公开(公告)号：US12128091B2
公开(公告)日：2024-10-29
申请号：US17505689
申请日：2021-10-20
Applicant: PAW POWER, INC.
Inventor： Anja Skodda
IPC: A61K38/39 , A23K20/111 , A23K20/121 , A23K20/147 , A23K20/163 , A23K20/174 , A23K50/40 , A61K31/355 , A61K31/375 , A61K31/593 , A61K31/7008 , A61K31/728
CPC classification number: A61K38/39 , A23K20/111 , A23K20/121 , A23K20/147 , A23K20/163 , A23K20/174 , A23K50/40 , A61K31/355 , A61K31/375 , A61K31/593 , A61K31/7008 , A61K31/728
Abstract: A food supplement is disclosed that comprises an extracellular matrix composition of hydrolyzed collagen, hyaluronic acid and glucosamine, ascorbic acid and, optionally, a cannabinoid composition. The food supplement can be given to pet animals for the relief of or prophylaxis of degenerative joint diseases, such as arthritis.
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公开(公告)号：US12109241B2
公开(公告)日：2024-10-08
申请号：US18094148
申请日：2023-01-06
Applicant: OSIRIS THERAPEUTICS, INC.
Inventor： Samson Tom , Alla Danilkovitch , Dana Yoo , Timothy Jansen , Jin-Qiang Kuang , Jennifer Michelle Marconi
CPC classification number: A61K35/28 , A01N1/0221 , A61K35/50 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K38/57 , C12N5/0605 , C12N2500/02 , C12N2501/115 , C12N2502/025
Abstract: Provided herein is a placental product comprising an immunocompatible chorionic membrane. Such placental products can be cryopreserved and contain viable therapeutic cells after thawing. The placental product of the present invention is useful in treating a patient with a tissue injury (e.g. wound or burn) by applying the placental product to the injury. Similar application is useful with ligament and tendon repair and for engraftment procedures such as bone engraftment.
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公开(公告)号：US20240307482A1
公开(公告)日：2024-09-19
申请号：US18735024
申请日：2024-06-05
Applicant: Illustris Pharmaceuticals, Inc.
Inventor： Siak Khim TAN
CPC classification number: A61K38/08 , A61K9/0014 , A61K9/06 , A61K31/728 , A61K38/05 , A61K38/06 , A61K38/07 , A61K38/39
Abstract: Compositions for dermal delivery of a topical solution and methods for using such compositions are described herein. The compositions may contain extracellular matrix components and therapeutic peptides.
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公开(公告)号：US12083166B2
公开(公告)日：2024-09-10
申请号：US18057110
申请日：2022-11-18
Applicant: Takashi Saito
Inventor： Jia Tang , Takashi Saito
CPC classification number: A61K38/39 , A61K33/42 , A61K38/014
Abstract: A tooth dentin, pulp or pulp tissue composition for treating or preventing a disease, disorder, or symptom of a tooth dentin and/or pulp or pulp tissue includes: (a) an integrin binding fragment of Laminin, the Laminin being selected from the group consisting of Laminin 511 and Laminin 411, the integrin binding fragment comprising an integrin-binding domain of the Laminin; and (b) a mixture of odontoblast and mineralized nodules secreted from the odontoblast. A coating density of the integrin binding fragment is 1 to 8 μg/cm2. The material (b) has been mixed with the material (a) in the composition so as to form pulp capping applicable to a tooth, such that the composition is able to treat or prevent the disease, disorder or symptom of the tooth dentin and/or pulp tissue including dental caries when applied to the tooth.
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公开(公告)号：US20240285701A1
公开(公告)日：2024-08-29
申请号：US18635627
申请日：2024-04-15
Inventor： Virginia Cornish , Amirhossein JAFARIYAN
IPC: A61K36/064 , A61K9/00 , A61K9/06 , A61K38/18 , A61K38/19 , A61K38/20 , A61K38/39 , A61K38/55 , A61K45/06 , A61K47/36 , A61P17/00 , A61P17/02 , A61P17/06
CPC classification number: A61K36/064 , A61K9/0014 , A61K9/06 , A61K38/1808 , A61K38/1841 , A61K38/1866 , A61K38/195 , A61K38/2026 , A61K38/39 , A61K38/55 , A61K45/06 , A61K47/36 , A61P17/00 , A61P17/02 , A61P17/06
Abstract: The disclosed subject matter provides for genetically modified cells, e.g., fungal cells, that autonomously generates and/or secretes one or more skin therapeutics, and methods of use thereof. In certain embodiments, the present disclosure provides genetically-engineered fungal cells that generate and secrete growth factors, protease inhibitors, cytokines and/or chemokines and methods of use thereof, e.g., for treating skin conditions.
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Patent Agency Ranking
公开(公告)号：US20240261335A1
公开(公告)日：2024-08-08
申请号：US18632923
申请日：2024-04-11
Applicant: Osiris Therapeutics, Inc.
Inventor： Timothy JANSEN , Samson TOM , Alla DANILKOVITCH , Dana YOO , Jaime ZERHUSEN
CPC classification number: A61K35/28 , A01N1/0221 , A61K35/50 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K38/57 , C12N5/0605 , C12N2500/02 , C12N2501/115 , C12N2502/025
Abstract: This invention provides a fluid therapeutic placental product comprising placental cells and a placental dispersion comprising placental factors. The placental cells and the placental dispersion are derived from placental tissue. A placental tissue can optionally be an amnion, chorion, or a trophoblast-depleted chorion. The placental product of the present invention is useful in treating a patient with a tissue injury (e.g. wound or burn) by applying the placental product to the injury. Similar application is useful with ligament and tendon repair and for engraftment procedures such as bone engraftment.
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公开(公告)号：US20240245731A1
公开(公告)日：2024-07-25
申请号：US18593225
申请日：2024-03-01
Applicant: BioStem Technologies, Inc.
Inventor： Jason V. MATUSZEWSKI , Wendy W. Weston
IPC: A61K35/50 , A61K31/726 , A61K31/728 , A61K38/17 , A61K38/18 , A61K38/20 , A61K38/39 , A61K41/10
CPC classification number: A61K35/50 , A61K31/726 , A61K31/728 , A61K38/179 , A61K38/1833 , A61K38/2006 , A61K38/39 , A61K41/10
Abstract: A sterile micronized composition prepared from intact human placental tissue for wound healing. The sterile micronized composition includes micronized human amnion; micronized human chorion; and micronized human intermediate spongy layer. In certain aspects, the composition is prepared from intact placental tissue comprising a human amnion layer, human chorion layer, and an intact human intermediate spongy layer positioned between the human amnion layer and human chorion layer such that immediately before micronization the human amnion layer and the human chorion layer are not separated from one another.
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公开(公告)号：US12037625B2
公开(公告)日：2024-07-16
申请号：US17670300
申请日：2022-02-11
Applicant: Avant Meats Company Limited
Inventor： Po San Mario Chin , Kai Yi Carrie Chan , Chun Hei Poon
IPC: A61K38/39 , A23J3/04 , A23J3/34 , A23L33/18 , A61K8/65 , A61K38/18 , A61Q19/00 , C07K1/12 , C12P21/06
CPC classification number: C12P21/06 , A23J3/04 , A23J3/342 , A23L33/18 , A61K8/65 , A61K38/18 , A61K38/39 , A61Q19/00 , C07K1/12 , A23V2002/00
Abstract: A cell hydrolysate composition is described, wherein the composition comprises substantially all protein polypeptides and/or polypeptide fragments derived substantially from all the proteins in a cell from an in vitro cell culture.
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公开(公告)号：US20240226242A9
公开(公告)日：2024-07-11
申请号：US18548413
申请日：2022-02-25
Applicant: JELLAGEN LTD
Inventor： Andrew Mearns SPRAGG , Almero BARNARD
IPC: A61K38/39 , A61K35/614 , A61K45/06 , A61P17/02
CPC classification number: A61K38/39 , A61K35/614 , A61K45/06 , A61P17/02
Abstract: The present invention relates to a collagenous marine invertebrate extract for use in the treatment of Epidermolysis Bullosa, pharmaceutical compositions comprising said collagenous marine invertebrate extract, and methods for manufacturing the collagenous marine invertebrate extract of the invention.
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公开(公告)号：US20240226179A1
公开(公告)日：2024-07-11
申请号：US17801959
申请日：2021-03-01
CPC classification number: A61K35/39 , A61K31/198 , A61K33/00 , A61K38/38 , A61K38/39 , A61P3/10 , C12N5/0018 , C12N5/0677
Abstract: This disclosure provides a culture media that facilitates survival and/or engraftment of transplanted cells. In one embodiment, this culture media comprises collagen I, albumin, L-glutamine and NaHCO3. In one embodiment, this culture media promotes enhanced survival and engraftment of β-cells of human pancreatic islets transplanted under the skin. The protective effect of this culture media is mediated, at least partly, by upregulating anti-apoptotic signaling pathways.
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