公开(公告)号：US20240123115A1

公开(公告)日：2024-04-18

申请号：US18395521

申请日：2023-12-23

申请人： 206 ORTHO, INC.

发明人： Jeffrey A. D'Agostino ,  Andrew J. CARTER ,  Craig M. Jones ,  Arthur Watterson

IPC分类号： A61L27/18 ,  A61K9/00 ,  A61K47/34 ,  A61L27/16 ,  A61L27/26 ,  A61L27/44 ,  A61L27/46 ,  A61L27/48 ,  A61L27/52 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58

CPC分类号： A61L27/18 ,  A61K9/0024 ,  A61K47/34 ,  A61L27/16 ,  A61L27/26 ,  A61L27/446 ,  A61L27/46 ,  A61L27/48 ,  A61L27/52 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/406 ,  A61L2300/604 ,  A61L2400/06 ,  A61L2430/02

摘要： A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.