公开(公告)号：US20240345074A1

公开(公告)日：2024-10-17

申请号：US18631488

申请日：2024-04-10

申请人： University of Pittsburgh - Of the Commonwealth System of Higher Education

发明人： Alexander Star ,  Wenting Shao

IPC分类号： G01N33/543 ,  G01N27/327 ,  G01N27/414 ,  G01N33/487

CPC分类号： G01N33/54346 ,  G01N27/3278 ,  G01N27/4145 ,  G01N27/4146 ,  G01N33/48714 ,  G01N2800/307

摘要： A sensor device for detecting an antigen in a fluid sample includes a sensor including a substrate and a sensor medium on the substrate. The sensor medium includes a plurality of single-walled carbon nanotubes having an enriched semiconducting content and one or more antibody fragments immobilized on the plurality of single-walled carbon nanotubes. Each of the one or more antibody fragments includes an active binding site for the antigen. The sensor device further includes electronic circuitry including at least one measurement system in operative connection with the sensor to measure a variable providing a measure of change in at least one property of the sensor medium which is dependent upon the presence of the antigen.

公开(公告)号：US20240332423A1

公开(公告)日：2024-10-03

申请号：US18739078

申请日：2024-06-10

申请人： Epinovatech AB

发明人： Martin Andreas Olsson

IPC分类号： H01L29/78 ,  G01N27/414 ,  G06N10/00 ,  H01L21/02 ,  H01L27/092 ,  H01L29/06 ,  H01L29/16 ,  H01L29/20 ,  H01L29/417 ,  H01L29/775 ,  H01L33/06 ,  H01L33/24 ,  H01L33/32 ,  H10N60/10 ,  H10N60/83 ,  H10N60/85

CPC分类号： H01L29/7851 ,  H01L21/02381 ,  H01L21/02527 ,  H01L21/02532 ,  H01L21/0254 ,  H01L21/02546 ,  H01L21/02603 ,  H01L21/0262 ,  H01L21/02639 ,  H01L27/0924 ,  H01L29/0676 ,  H01L29/16 ,  H01L29/1606 ,  H01L29/20 ,  H01L29/775 ,  H01L33/06 ,  H01L33/24 ,  H01L33/32 ,  H10N60/128 ,  H10N60/83 ,  H10N60/85 ,  G01N27/4146 ,  G06N10/00 ,  H01L29/41791

摘要： A reinforced thin-film device is disclosed. The reinforced thin-film device comprising: a substrate having a top surface for supporting an epilayer; a mask layer patterned with a plurality of nanosize cavities disposed on said substrate to form a needle pad; a thin-film of, relative to the substrate, lattice-mismatched semiconductor disposed on said mask layer, wherein said thin-film comprises a plurality of in parallel spaced semiconductor needles of said lattice-mismatched semiconductor embedded in said thin-film, wherein said plurality of semiconductor needles are vertically disposed in the axial direction towards said substrate in said plurality of nanosize cavities of said mask layer; a, relative to the substrate, lattice-mismatched semiconductor epilayer provided on said thin-film and supported thereby; and a FinFET transistor arranged on the lattice-mismatched semiconductor epilayer. The FinFET transistor comprising: a fin semiconductor structure comprising an elongate protruding core portion, the fin semiconductor structure being arranged on the lattice-mismatched semiconductor epilayer, a first and a second nanostructured electrode radially enclosing respectively a source end and a drain end of the protruding core portion, and a nanostructured gate electrode radially enclosing a central portion of the protruding core portion, the central portion being a portion of the protruding core portion between the source end and the drain end.

公开(公告)号：US12072313B2

公开(公告)日：2024-08-27

申请号：US17403915

申请日：2021-08-17

申请人： Murata Manufacturing Co., Ltd. ,  OSAKA UNIVERSITY

发明人： Naruto Miyakawa ,  Ayumi Shinagawa ,  Shota Ushiba ,  Masahiko Kimura ,  Kazuhiko Matsumoto ,  Takao Ono

IPC分类号： H01L23/00 ,  G01N27/414 ,  H01L29/16

CPC分类号： G01N27/4145 ,  G01N27/4146 ,  H01L29/1606

摘要： A graphene transistor includes a graphene layer including at least one sheet of graphene, a drain electrode and a source electrode each electrically connected to the graphene layer, a charge donor on at least one main surface of the graphene layer, the charge donor including an impurity charge, and a counter ion having a charge with a sign different from a sign of the impurity charge.

公开(公告)号：US12055517B2

公开(公告)日：2024-08-06

申请号：US16759432

申请日：2018-10-29

申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

发明人： Oh Seok Kwon ,  Chang Soo Lee ,  Seon Joo Park ,  Tai Hwan Ha ,  Chul Soon Park ,  Kyung Ho Kim ,  Jin Yeong Kim

IPC分类号： B32B9/00 ,  C01B32/186 ,  C01B32/194 ,  G01N27/414 ,  H10K85/20 ,  H10K85/60 ,  B82Y30/00

CPC分类号： G01N27/4145 ,  C01B32/186 ,  C01B32/194 ,  G01N27/4146 ,  H10K85/20 ,  H10K85/6572 ,  B82Y30/00 ,  C01B2204/02 ,  C01B2204/04 ,  C01B2204/22 ,  C01P2002/82 ,  C01P2002/86 ,  Y10T428/30

摘要： The present invention relates to a graphene transistor comprising: a substrate; a graphene channel layer arranged on the substrate; a pair of metals spaced from each other and respectively arranged at opposite ends of the graphene channel layer; and a linker layer arranged on the graphene channel layer and including an N-heterocyclic carbene compound, a fabrication method therefor, and a biosensor comprising the same. The graphene transistor according to the present invention in which the carbene group of the N-heterocyclic carbene compound forms a covalent bond with the graphene channel layer to modify the whole surface of the graphene channel layer exhibits excellent electric conductivity as a transistor and a biosensor comprising the transistor is improved in selectivity and sensitivity.

公开(公告)号：US20240219343A1

公开(公告)日：2024-07-04

申请号：US18149200

申请日：2023-01-03

申请人： GlobalFoundries Singapore Pte. Ltd.

发明人： Chia Ching Yeo ,  Khee Yong Lim ,  Kiok Boone Elgin Quek

IPC分类号： G01N27/414

CPC分类号： G01N27/4146 ,  G01N27/4148

摘要： A device for analyte sensing and method of forming the device. The device includes a first semiconductor layer including a source region, a drain region and a stack of semiconductor nanosheets extending between the source region and the drain region; a first dielectric layer on the semiconductor layer; and a cavity extending through the first dielectric layer and the first semiconductor layer. The semiconductor nanosheets are disposed within the cavity, and a portion of the cavity resides in between the semiconductor nanosheets.

公开(公告)号：US20240210350A1

公开(公告)日：2024-06-27

申请号：US18423977

申请日：2024-01-26

申请人： Government of the United States as Represented by the Secretary of the Air Force

发明人： Steve S Kim ,  Rajesh Naik ,  Claude C Grigsby ,  Jennifer A. Martin ,  Michael Brothers ,  Yen H Ngo

IPC分类号： G01N27/414

CPC分类号： G01N27/4141 ,  G01N27/4146

摘要： Disclosed is a selective chemical sensor, methods of production, and methods of use, where the sensor utilizes an electrochemical sensor element protected by a semi-selective polymeric matrix in conjunction with a selecting compound doped into the matrix along with an acid or base. The polymeric matrix serves as an analyte capture matrix, while the selecting compound reacts with the analyte, further improving the selectivity of the sensor.

公开(公告)号：US12007354B2

公开(公告)日：2024-06-11

申请号：US17090982

申请日：2020-11-06

申请人： Kenneth S. Burch ,  Tim van Opijnen ,  Jianmin Gao ,  Narendra Kumar ,  Juan C. Ortiz-Marquez ,  Wenjian Wang ,  Mason Gray

发明人： Kenneth S. Burch ,  Tim van Opijnen ,  Jianmin Gao ,  Narendra Kumar ,  Juan C. Ortiz-Marquez ,  Wenjian Wang ,  Mason Gray

IPC分类号： G01N27/414

CPC分类号： G01N27/4145 ,  G01N27/4146 ,  G01N27/4148

摘要： A method and system for label-free detection of pathogenic and antibiotic resistant bacteria is disclosed. The method includes fabricating a G-FET/peptide device having a synthesized peptide probe capable of recognizing and binding to a bacterial target; performing electric-field assisted binding of at least one bacterial cell of the bacterial target to the G-FET/peptide device; and electrically detecting the binding of the at least one bacterial cell to the G-FET/peptide device.

公开(公告)号：US20240165624A1

公开(公告)日：2024-05-23

申请号：US18359237

申请日：2023-07-26

申请人： PLENO, INC.

发明人： Pieter VAN ROOYEN ,  Lorenzo BERTI ,  Jeffrey BRODIN ,  Michael POLLACK

IPC分类号： B01L3/00 ,  G01N27/414

CPC分类号： B01L3/502792 ,  G01N27/4146 ,  G01N27/4148 ,  B01L2300/0645 ,  B01L2300/0829 ,  B01L2300/0893 ,  B01L2300/0896 ,  B01L2300/161 ,  B01L2400/0427

摘要： A droplet manipulation device comprising, which may, for example, include (a) a first substrate having a first layer comprising a first array of electrowetting electrodes, and a second layer atop a region of the first layer comprising a second array of electrowetting electrodes; and (b) a second substrate separated from the first substrate forming a droplet operations gap between the first and second substrates.

公开(公告)号：US11912577B2

公开(公告)日：2024-02-27

申请号：US17525873

申请日：2021-11-13

申请人： Lin Shao

发明人： Lin Shao

IPC分类号： C01B32/186 ,  C02F1/44 ,  H01L29/16 ,  H01L29/423 ,  G01N27/414 ,  B82Y40/00

CPC分类号： C01B32/186 ,  C02F1/442 ,  G01N27/4146 ,  H01L29/1606 ,  H01L29/42356 ,  B82Y40/00 ,  C01P2004/13 ,  C01P2004/64 ,  C01P2006/16

摘要： Provided herein are methods for creating or fabricating nanopore(s) on a membrane. The membrane is bombarded by ions, for example, C60 ions through at least one nanotunnel through a mask that is positioned on the membrane. Also provided is a two dimensional membrane with at least one nanopore thereon fabricated via these methods.

公开(公告)号：US11906459B2

公开(公告)日：2024-02-20

申请号：US17292844

申请日：2019-08-16

申请人： National Research Council of Canada

发明人： Jacques Lefebvre ,  François Lapointe

IPC分类号： G01N27/22 ,  G01N27/12 ,  G01N27/414

CPC分类号： G01N27/225 ,  G01N27/121 ,  G01N27/4141 ,  G01N27/4146

摘要： An electronic device for sensing a target analyte in a gas, liquid or vapor sample, the device has at least two sensing elements, each sensing element having an exposed layer of a transduction material supported on a dielectric substrate. The dielectric substrate of at least one of the sensing elements is made of a different dielectric material than the dielectric substrate of at least one other of the sensing elements. The different dielectric materials providing a different sensing response according to one or more transduction modes. The plurality of sensing elements in the device yield a specific transduction pattern for a specific target analyte in a gas, liquid or vapor sample.