公开(公告)号：US20240103028A1

公开(公告)日：2024-03-28

申请号：US18262469

申请日：2022-02-17

Applicant: LEADWAY (HK) LIMITED

Inventor： Wei FANG ,  Linyong TANG ,  Shengqiang LIU ,  Yongchao WEI ,  Tao SHANG

IPC: G01N35/04 ,  G01N21/13

CPC classification number: G01N35/04 ,  G01N21/13 ,  G01N2035/00742 ,  G01N2035/0475

Abstract: An analyzer and a method for reading a test result of a test apparatus are provided. The analyzer includes an analyzer (1) housing, and a drive system, a photoelectric system, a data processing system and a result output system disposed in the analyzer (1) housing. The test apparatus is carried by an objective stage (10) of the drive system to get in and out of the analyzer (1) to read the test result. The analyzer (1) compact in size and stable in operation is applicable to testing of various biochemical indicators and can improve the efficiency of medical testing.

公开(公告)号：US20240044807A1

公开(公告)日：2024-02-08

申请号：US18356096

申请日：2023-07-20

Applicant: TOKYO ELECTRON LIMITED

Inventor： Tomoya ENDO ,  Kentaro Konishi ,  Yuki Ishida ,  Jun Fujihara

IPC: G01N21/95 ,  H01L21/66 ,  G01N21/13

CPC classification number: G01N21/9501 ,  H01L22/12 ,  G01N21/13 ,  G01N2201/0461 ,  G01N2201/025 ,  G01N2201/0227 ,  G01N2021/0112

Abstract: There is an inspection system including multiple inspection units configured to inspect substrates, wherein each of the inspection units includes: a tester configured to inspect a substrate; a moving part configured to hold and move the substrate relative to the tester; and a frame structure configured to accommodate the tester and the moving part, wherein the frame structure of one inspection unit includes: a first frame to be connected to a frame structure of another inspection unit; and a second frame that accommodates at least the moving part and is configured to move relative to the first frame to extract the moving part from the first frame.

公开(公告)号：US11815446B2

公开(公告)日：2023-11-14

申请号：US16072427

申请日：2017-01-24

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Patrick Wissmann ,  Benjamin S. Pollack ,  Ludwig Listl

IPC: G01N21/13 ,  G01N21/25 ,  G01N15/04 ,  G01N35/00 ,  G01N21/88

CPC classification number: G01N21/13 ,  G01N15/042 ,  G01N21/253 ,  G01N21/255 ,  G01N21/88 ,  G01N35/00663 ,  G01N35/00613 ,  G01N2015/045 ,  G01N2021/8845 ,  G01N2201/0627

Abstract: A quality check module for characterizing a specimen and/or a specimen container. The quality check module includes an imaging location within the quality check module configured to receive a specimen container containing a specimen, one or more cameras located at one or more viewpoints adjacent to the imaging location, and one or more spectrally-switchable light source including a light panel assembly located adjacent the imaging location and configured to provide lighting for the one or more cameras, the spectrally-switchable light source configured to be operatively switchable between multiple different spectra. Methods of imaging a specimen and/or specimen container and specimen, and specimen testing apparatus including a quality check module adapted to carry out the method are described herein, as are other aspects.

公开(公告)号：US11714049B2

公开(公告)日：2023-08-01

申请号：US17673051

申请日：2022-02-16

Applicant: Otsuka Pharmaceutical Co., Ltd.

Inventor： Nobuhiro Yamauchi ,  Yuichi Kyogoku

IPC: G01N21/64 ,  G01N21/13 ,  G01N21/41 ,  G01N21/552 ,  G01N21/84

CPC classification number: G01N21/648 ,  G01N21/13 ,  G01N21/41 ,  G01N21/553 ,  G01N2021/8455

Abstract: The present invention includes a prism having a light incidence surface and a film formation surface, a metal film disposed on the film formation surface, and a trapping body secured to the metal film. Excitation light is irradiated from an excitation light irradiation part onto an analysis chip installed in a chip holder, and excitation light reflected by the analysis chip is detected. The information outputted by the excitation light irradiation part is acquired.

公开(公告)号：US20190194765A1

公开(公告)日：2019-06-27

申请号：US16287275

申请日：2019-02-27

Applicant: GeneWeave Biosciences, Inc.

Inventor： Diego Ariel REY ,  Shaunak ROY ,  Leonardo Maestri TEIXEIRA ,  Ryan C. GRISWOLD ,  Kenneth G. OLSON ,  Bruce J. RICHARDSON ,  Victor H. YEE ,  Werner FREI

IPC: C12Q1/6897 ,  B01L3/00 ,  G01N21/13 ,  B01L7/00 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/06 ,  C12Q1/10 ,  C12Q1/14 ,  C12Q1/66 ,  G01N21/76 ,  G01N21/03 ,  G01N21/01 ,  G01J1/00

CPC classification number: C12Q1/6897 ,  B01L3/502 ,  B01L3/50825 ,  B01L3/52 ,  B01L3/523 ,  B01L3/54 ,  B01L3/545 ,  B01L7/00 ,  B01L2200/028 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/042 ,  B01L2300/047 ,  B01L2300/049 ,  B01L2300/0672 ,  B01L2400/0478 ,  B01L2400/06 ,  B01L2400/0683 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/06 ,  C12Q1/10 ,  C12Q1/14 ,  C12Q1/66 ,  G01J1/00 ,  G01N21/01 ,  G01N21/03 ,  G01N21/13 ,  G01N21/76 ,  G01N21/763 ,  G01N2035/00346 ,  G01N2035/0405 ,  G01N2333/195

Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.

公开(公告)号：US20180333714A1

公开(公告)日：2018-11-22

申请号：US16031181

申请日：2018-07-10

Applicant: Dale Lee Heintzelman ,  John Lloyd Bowman ,  Rick Jackson

Inventor： Dale Lee Heintzelman ,  John Lloyd Bowman ,  Rick Jackson

IPC: B01L3/02 ,  G01N1/14 ,  B01L9/00 ,  G01N21/01 ,  G01N21/03 ,  G01N21/13 ,  G01N21/59 ,  G01N35/10

CPC classification number: B01L3/0275 ,  G01N21/01 ,  G01N21/03 ,  G01N21/031 ,  G01N21/13 ,  G01N21/59

Abstract: This disclosure is directed to exemplary embodiments of systems, methods, techniques, processes, products and product components that can facilitate users making improved absorbance or fluorescence measurements in the field of spectroscopy with reduced (minimal) sample waste, and increased throughput, particularly in the study of biological sciences. A method and device for photometric measurement of liquids. The method includes the steps of: The method includes the steps of: providing a pipette tip, the pipette tip being made of an optically clear body having an outer wall and an inner wall, the inner wall defining an inner space for receiving a liquid sample, the inner space providing a cross-sectional path length for light; positioning the pipette tip between a light source and a light collector; measuring light transmission through the liquid sample; adjusting the inner space of the pipette tip to change the cross-sectional length, and measuring light transmission through the liquid sample. This can be accomplished by moving the light source from a first position to at least a second position to provide a plurality of cross-sectional path lengths through the liquid sample or by moving the pipette tip from a first position to at least a second position to provide a plurality of cross-sectional path lengths through the liquid sample.

公开(公告)号：US09976174B2

公开(公告)日：2018-05-22

申请号：US15077182

申请日：2016-03-22

Applicant: Illumina Cambridge Limited

Inventor： Stephen Rawlings ,  Venkatesh Mysore Nagaraja Rao ,  Beng Keong Ang ,  Nitin Udpa

IPC: C12M1/00 ,  C12Q1/68 ,  G01N21/13 ,  G01N21/25 ,  G01N21/64 ,  G02B21/34 ,  G01N35/10 ,  B01L9/00 ,  G01N35/00 ,  B01L3/00 ,  B01L7/00

CPC classification number: C12Q1/6837 ,  B01L3/5027 ,  B01L7/52 ,  B01L9/52 ,  B01L9/527 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0822 ,  B01L2300/0877 ,  C12Q1/6869 ,  G01N21/13 ,  G01N21/253 ,  G01N21/6452 ,  G01N35/04 ,  G01N35/1095 ,  G01N2035/00356 ,  G01N2035/00752 ,  G01N2035/0091 ,  G01N2201/025 ,  G02B21/34

Abstract: Method includes positioning a first carrier assembly on a system stage. The carrier assembly includes a support frame having an inner frame edge that defines a window of the support frame. The first carrier assembly includes a first substrate that is positioned within the window and surrounded by the inner frame edge. The first substrate has a sample thereon. The method includes detecting optical signals from the sample of the first substrate. The method also includes replacing the first carrier assembly on the system stage with a second carrier assembly on the system stage. The second carrier assembly includes the support frame and an adapter plate held by the support frame. The second carrier assembly has a second substrate held by the adapter plate that has a sample thereon. The method also includes detecting optical signals from the sample of the second substrate.

公开(公告)号：US20170058321A1

公开(公告)日：2017-03-02

申请号：US15263463

申请日：2016-09-13

Applicant: UNIVERSAL BIO RESEARCH CO., LTD.

Inventor： Hideji Tajima

IPC: C12Q1/68 ,  G01N21/64 ,  G01N21/13 ,  G01N21/31 ,  G01N35/00 ,  G01N35/10

CPC classification number: C12Q1/686 ,  B01L7/52 ,  B01L7/54 ,  B01L2300/1805 ,  C12Q1/6848 ,  G01N21/13 ,  G01N21/31 ,  G01N21/6428 ,  G01N21/6452 ,  G01N35/0098 ,  G01N35/10 ,  G01N35/1065 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2035/00366 ,  G01N2035/00376 ,  G01N2035/103 ,  G01N2035/1076 ,  G01N2201/08 ,  G01N2203/0226

Abstract: The invention relates to an automatic response/light measurement device and a method therefor, and the purpose is to effectively and quickly perform an optical measurement relating to a reaction with high reliability without increasing a device size. The device is configured to have: a container group in which a plurality of reaction containers are arranged; a measurement mount provided with a plurality of coupling ends that are joinable with apertures of the reaction containers, and have light guide portions that optically connect with the interior of the joined reaction containers; a mount transfer mechanism; a measuring device having a measuring end having at least one light guide portion that is optically connectable to the light guide portions of the coupling ends, that is able to receive light based on an optical state within the reaction containers; an on-mount measuring end transfer mechanism; and a measurement control portion.

公开(公告)号：US09551649B2

公开(公告)日：2017-01-24

申请号：US14723628

申请日：2015-05-28

Applicant: SRC, Inc.

Inventor： Stephen R. Houghton ,  Marc P. Roberts ,  Nicole J. Surace Clayton ,  James W. McLean ,  Robert M. Cannon

IPC: G01J3/44 ,  G01N21/03 ,  G01N1/10 ,  G01N33/22 ,  G01N21/65 ,  G01N1/02

CPC classification number: G01N21/0303 ,  G01N1/02 ,  G01N1/10 ,  G01N21/13 ,  G01N21/65 ,  G01N33/227 ,  G01N2001/022 ,  G01N2001/027 ,  G01N2001/028 ,  G01N2021/651 ,  G01N2201/0221

Abstract: A system, method, and device for analyzing a sample using spectroscopy. The system includes a spectroscope, a sample vial with a swab removably sealable within a transparent enclosure, the swab including an absorbent collection substrate. The system further includes a sample vial adaptor configured to affix to the spectroscope, and a sample vial receptacle that receives the sample vial. The adaptor is configured to position the sample vial such that the transparent portion of the enclosure is between the swab and the laser of the Raman instrument, and such that the swab is positioned at the focal distance of the laser.

Abstract translation: 用于使用光谱分析样品的系统，方法和装置。 该系统包括分光镜，具有可拆卸地密封在透明外壳内的拭子的样品瓶，拭子包括吸收收集基底。 该系统还包括配置成附着到分光镜的样品瓶适配器和接收样品瓶的样品瓶容器。 适配器被配置为定位样品瓶，使得外壳的透明部分在拭子和拉曼仪器的激光之间，并且使得棉签位于激光器的焦距处。

公开(公告)号：US09481903B2

公开(公告)日：2016-11-01

申请号：US13802461

申请日：2013-03-13

Applicant: GeneWeave Biosciences, Inc.

Inventor： Diego Ariel Rey ,  Shaunak Roy ,  Leonardo Maestri Teixeira ,  Ryan C. Griswold ,  Kenneth G. Olson ,  Bruce J. Richardson ,  Victor Yee

IPC: C12Q1/70 ,  C12Q1/66 ,  C12Q1/02 ,  C12Q1/68 ,  G01N21/00 ,  C12Q1/04 ,  B01L3/00 ,  G01N21/01 ,  G01N21/76 ,  G01N21/03 ,  G01N21/13 ,  B01L7/00 ,  G01J1/00 ,  G01N35/00 ,  G01N35/04

CPC classification number: C12Q1/6897 ,  B01L3/502 ,  B01L3/50825 ,  B01L3/52 ,  B01L3/523 ,  B01L3/54 ,  B01L3/545 ,  B01L7/00 ,  B01L2200/028 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/042 ,  B01L2300/047 ,  B01L2300/049 ,  B01L2300/0672 ,  B01L2400/0478 ,  B01L2400/06 ,  B01L2400/0683 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/06 ,  C12Q1/10 ,  C12Q1/14 ,  C12Q1/66 ,  G01J1/00 ,  G01N21/01 ,  G01N21/03 ,  G01N21/13 ,  G01N21/76 ,  G01N21/763 ,  G01N2035/00346 ,  G01N2035/0405 ,  G01N2333/195

Abstract: Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.