公开(公告)号：US20240325583A1

公开(公告)日：2024-10-03

申请号：US18629690

申请日：2024-04-08

Applicant: Fisher & Paykel Healthcare Limited

Inventor： Nordyn ALAMI

IPC: A61L2/24 ,  A61L2/10 ,  A61L2/26 ,  A61M16/00 ,  A61M16/16 ,  C12Q1/04

CPC classification number: A61L2/24 ,  A61L2/10 ,  A61L2/26 ,  A61M16/0051 ,  A61M16/0066 ,  A61M16/16 ,  C12Q1/04 ,  A61L2202/11 ,  A61L2202/14 ,  A61L2202/24 ,  A61L2209/111 ,  A61M2202/203 ,  A61M2205/0205 ,  A61M2205/11 ,  A61M2205/3303 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/60 ,  A61M2205/6018 ,  A61M2205/7563 ,  A61M2209/10

Abstract: A breathing treatment apparatus delivers breathing gas to a user. The apparatus May be configured to comprise one or more sensors for sensing microbial growth within the apparatus.

公开(公告)号：US20240299149A1

公开(公告)日：2024-09-12

申请号：US17951483

申请日：2022-09-23

Applicant: Cell and Molecular Tissue Engineering, LLC

Inventor： Ulrike W. Klueh ,  Donald L. Kreutzer

IPC: A61F2/00 ,  A61L31/10 ,  A61L31/16 ,  A61M5/158

CPC classification number: A61F2/0063 ,  A61L31/10 ,  A61L31/16 ,  A61M5/158 ,  A61B5/14532 ,  A61B5/686 ,  A61B2562/18 ,  A61F2240/001 ,  A61F2250/0067 ,  A61L2300/414 ,  A61L2300/64 ,  A61M2005/1581 ,  A61M2205/0205

Abstract: Disclosed herein are medical products, including an implantable device coated with an extracellular matrix comprising Type IV collagen and laminin, wherein the implantable device comprises at least one member selected from the group consisting of sensors, meshes and cannulas, and the extracellular matrix contains no more than 0.024 mg/ml total concentration of glucose, amino acids and salts having a molecular weight of 2000 daltons or less. Corresponding systems and method also are disclosed.

公开(公告)号：US12083309B2

公开(公告)日：2024-09-10

申请号：US17390859

申请日：2021-07-30

Applicant: Medline Industries, Inc.

Inventor： Scott Bedoe ,  James Burgess ,  Brent Skupien ,  Christopher Dalton ,  Pere Berkowitz ,  David Noskowicz

IPC: A61M39/16 ,  A61M39/20

CPC classification number: A61M39/20 ,  A61M39/16 ,  A61M2205/0205

Abstract: A device for cleaning medical implements is disclosed, in particular a device for cleaning vascular or other fluid access sites. The device includes a cap having an opening to receive an access site. The cap may be used in the following manner: A healthcare worker may, with gloved hands, open the cap packaging and place the cap over the port of a medical implement to be cleaned. The healthcare worker may wipe the site by either applying a turning motion or by simply pushing the cap onto the port. The cap could then remain secured in place by threads other mechanisms. A cap in place on a medical implement may be a positive indication that a desired site of the medical implement is clean. The cap may include a disinfecting substance.

公开(公告)号：US20240261548A1

公开(公告)日：2024-08-08

申请号：US18577719

申请日：2022-03-22

Applicant: NANTONG TEXTILE & SILK INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE ,  SOOCHOW UNIVERSITY

Inventor： Gang LI ,  Lu LI ,  Feng LI ,  Lirong DUAN

IPC: A61M27/00 ,  A61L31/02 ,  A61L31/04 ,  A61L31/10 ,  A61L31/16

CPC classification number: A61M27/008 ,  A61L31/022 ,  A61L31/04 ,  A61L31/10 ,  A61L31/16 ,  A61M2205/0205 ,  A61M2205/0216 ,  A61M2207/00 ,  A61M2210/1089

Abstract: A long-acting antibacterial anti-stenosis functional urethral stent and preparation method thereof is provided; the urethral stent is a tubular structure consisting of three layers: inner, middle and outer layers; the middle layer is a fabric tube; the outer layer is a silk fibroin film carrying anti-stenosis drugs; the inner layer is an antibacterial antifouling coating, consisting of chitosan-nanosilica arrays, villi, microvilli and antibacterial drugs; the preparation method includes: after making yarns into the fabric tube by textile molding, preparing the antibacterial and anti-fouling coating on the inner surface, and the silk fibroin film carrying anti-stenosis drugs on the outer surface respectively, to obtain the long-acting antibacterial anti-stenosis functional urethral stent. The method is simple, and the prepared urethral stent has a smooth surface and good biocompatibility, which has excellent properties such as radial compression force, circumferential expansion force, resistance to bending and torsion and elastic recovery.

公开(公告)号：US12029835B2

公开(公告)日：2024-07-09

申请号：US16785342

申请日：2020-02-07

Applicant: CareFusion 303, Inc.

Inventor： Todd Oda ,  George Mansour ,  Ali Saleh ,  Tomas Frausto ,  Siddarth K. Shevgoor ,  Archana Nagaraja Rao

IPC: A61L29/16 ,  A61K31/155 ,  A61L29/08 ,  A61M39/00 ,  A61M39/02 ,  A61M39/10 ,  A61M39/24 ,  A61M39/26

CPC classification number: A61L29/16 ,  A61K31/155 ,  A61L29/085 ,  A61M39/02 ,  A61M39/10 ,  A61M39/24 ,  A61M39/26 ,  A61L2300/206 ,  A61L2300/404 ,  A61M2039/0036 ,  A61M2039/027 ,  A61M2039/0285 ,  A61M2039/2433 ,  A61M2205/0205

Abstract: A valve including an antimicrobial agent can be used with needleless access connectors. The valve can have an insert that includes an antimicrobial coating thereon and/or the valve can have physical features, such as a series of tunnels or groves or a patterned surface, containing an antimicrobial formulation and/or the valve can be made of a material that includes an antimicrobial agent.

公开(公告)号：US20240165303A1

公开(公告)日：2024-05-23

申请号：US18431234

申请日：2024-02-02

Applicant: Urotronic, Inc.

Inventor： Lixiao Wang ,  Peter Barnett ,  David Hendrickson

IPC: A61L29/08 ,  A61L29/06 ,  A61L29/16 ,  A61M25/10 ,  A61M29/02 ,  A61B1/307

CPC classification number: A61L29/08 ,  A61L29/06 ,  A61L29/085 ,  A61L29/16 ,  A61M25/1002 ,  A61M25/10185 ,  A61M29/02 ,  A61B1/307 ,  A61L2300/416 ,  A61L2300/426 ,  A61M2025/105 ,  A61M2025/1075 ,  A61M2202/0488 ,  A61M2205/0205 ,  A61M2210/0681 ,  A61M2210/1032 ,  A61M2210/1039 ,  A61M2210/105 ,  A61M2210/1053 ,  A61M2210/1057 ,  A61M2210/106 ,  A61M2210/1064 ,  A61M2210/1078 ,  A61M2210/1085 ,  A61M2210/1096 ,  A61M2210/166

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

公开(公告)号：US20240164708A1

公开(公告)日：2024-05-23

申请号：US18524346

申请日：2023-11-30

Applicant: Eyenovia, Inc.

Inventor： Bernard L. Ballou, JR. ,  Mark Packer ,  Russell John Mumper ,  Tsontcho Ianchulev

IPC: A61B5/00 ,  A61B3/14 ,  A61B5/11 ,  A61F9/00 ,  A61K8/06 ,  A61K9/00 ,  A61M11/00 ,  A61M11/04 ,  A61M15/00 ,  A61M15/02 ,  B05B17/00 ,  B05B17/06 ,  G16H10/60 ,  G16H15/00 ,  G16H20/10 ,  G16H20/17 ,  G16H30/20 ,  G16H40/63 ,  G16H40/67 ,  G16Z99/00

CPC classification number: A61B5/4839 ,  A61B3/14 ,  A61F9/0008 ,  G16H20/10 ,  A61B5/0059 ,  A61B5/0079 ,  A61B5/1103 ,  A61F9/00 ,  A61F9/0026 ,  A61K8/06 ,  A61K9/0048 ,  A61M11/00 ,  A61M11/005 ,  A61M11/042 ,  A61M15/008 ,  A61M15/0083 ,  A61M15/025 ,  A61M2205/0205 ,  A61M2205/0238 ,  A61M2205/3306 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/36 ,  A61M2205/3673 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/587 ,  A61M2205/8206 ,  A61M2209/086 ,  A61M2210/0612 ,  B05B17/0646 ,  B05B17/0661 ,  B05B17/0676 ,  G16H10/60 ,  G16H15/00 ,  G16H20/17 ,  G16H30/20 ,  G16H40/63 ,  G16H40/67 ,  G16Z99/00

Abstract: The present invention includes and provides a method of delivering a medicament to an eye of a subject in need thereof a solution, the method comprising: (a) providing droplets containing the medicament with a specified average size and average initial ejecting velocity, and (b) delivering the medicament to the eye, where the droplets deliver a percentage of the ejected mass of the droplets to the eye.

公开(公告)号：US11938297B2

公开(公告)日：2024-03-26

申请号：US16994584

申请日：2020-08-15

Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION

Inventor： Dustin Williams ,  Nicholas Ashton

IPC: A61M39/02 ,  A61M31/00 ,  A61M39/10

CPC classification number: A61M39/0247 ,  A61M31/002 ,  A61M39/1011 ,  A61M2039/0205 ,  A61M2039/0276 ,  A61M2039/0288 ,  A61M2205/0205 ,  A61M2205/04 ,  A61M2209/045 ,  A61M2210/02

Abstract: Methods and devices for eradicating biofilms and planktonic bacteria are provided. In on embodiment, a therapeutic delivery device comprised of at least a port and a antimicrobial releasing pouch and one or more therapeutic agents is provided to the mammal. In one aspect of at least one embodiment the releasing pouch has an internal reservoir comprised of a membrane that is configured to contain the one or more therapeutic agents that is to be administered to the mammal and the port is in fluid communication with the pouch and configured such that the pouch can be refilled with one or more therapeutic agents via the port. In other aspect of at least one embodiment the method is able to fully eradicate 109 colony forming units (CFU) of methicillin-resistant Staphylococcus aureus (MRSA) within a 24 hr period.

公开(公告)号：US11938287B2

公开(公告)日：2024-03-26

申请号：US17944259

申请日：2022-09-14

Applicant: Urotronic, Inc.

Inventor： Lixiao Wang ,  Peter Barnett ,  David Hendrickson

IPC: A61M25/10 ,  A61B1/00 ,  A61B1/307 ,  A61L29/06 ,  A61L29/08 ,  A61L29/16 ,  A61M25/00

CPC classification number: A61M25/1002 ,  A61L29/06 ,  A61L29/08 ,  A61L29/085 ,  A61L29/16 ,  A61B1/00082 ,  A61B1/307 ,  A61L2300/416 ,  A61L2300/426 ,  A61M2025/0081 ,  A61M25/10185 ,  A61M2025/105 ,  A61M2025/1059 ,  A61M2025/1075 ,  A61M2202/0488 ,  A61M2205/0205 ,  A61M2210/0681 ,  A61M2210/105 ,  A61M2210/1085 ,  A61M2210/1096 ,  A61M2210/166

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

公开(公告)号：US11925729B2

公开(公告)日：2024-03-12

申请号：US17967259

申请日：2022-10-17

Applicant: Urotronic, Inc.

Inventor： Lixiao Wang ,  Peter Barnett ,  David Hendrickson

IPC: A61L29/08 ,  A61B1/307 ,  A61L29/06 ,  A61L29/16 ,  A61M25/10 ,  A61M29/02

CPC classification number: A61L29/08 ,  A61L29/06 ,  A61L29/085 ,  A61L29/16 ,  A61M25/1002 ,  A61M25/10185 ,  A61M29/02 ,  A61B1/307 ,  A61L2300/416 ,  A61L2300/426 ,  A61M2025/105 ,  A61M2025/1075 ,  A61M2202/0488 ,  A61M2205/0205 ,  A61M2210/0681 ,  A61M2210/1032 ,  A61M2210/1039 ,  A61M2210/105 ,  A61M2210/1053 ,  A61M2210/1057 ,  A61M2210/106 ,  A61M2210/1064 ,  A61M2210/1078 ,  A61M2210/1085 ,  A61M2210/1096 ,  A61M2210/166

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.