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    DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS
    4.
    发明申请
    DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS 有权

    公开(公告)号：US20230050453A1

    公开(公告)日：2023-02-16

    申请号：US17967259

    申请日：2022-10-17

    申请人： Urotronic, Inc.

    发明人： Lixiao Wang ,  Peter Barnett ,  David Hendrickson

    IPC分类号： A61L29/08 ,  A61M25/10 ,  A61L29/16 ,  A61L29/06 ,  A61M29/02 ,  A61B1/307

    摘要： Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

    Drug coated balloon catheters for nonvascular strictures
    5.
    发明授权
    Drug coated balloon catheters for nonvascular strictures 有权

    公开(公告)号：US10888640B2

    公开(公告)日：2021-01-12

    申请号：US15568614

    申请日：2016-04-21

    申请人： Urotronic, Inc.

    发明人： Lixiao Wang ,  Peter Barnett

    IPC分类号： A61L29/16 ,  A61L29/08 ,  A61K31/337 ,  A61K31/439 ,  A61P31/00 ,  A61P37/06 ,  A61M25/10

    摘要： Embodiments of the present invention provide a method of treating a stricture in a nonvascular body lumen such as urethral strictures, benign prostatic hyperplasia (BPH) strictures, ureteral strictures, esophageal strictures, sinus strictures, and biliary tract strictures. Embodiments of the present invention provide a method for treating at least one of benign prostatic hyperplasia (BPH), prostate cancer, asthma, and chronic obstructive pulmonary disease (COPD). The method can include delivering, for example, via drug coated balloon catheters, anti-inflammatory and anti-proliferative drugs (e.g., rapamycin, paclitaxel, and their analogues) and one or more additives.

    Drug Coated Balloon Catheters for Nonvascular Strictures
    7.
    发明申请
    Drug Coated Balloon Catheters for Nonvascular Strictures 审中-公开
    用于非血管狭窄的药物涂层气球导管

    公开(公告)号：US20150273117A1

    公开(公告)日：2015-10-01

    申请号：US14438327

    申请日：2013-10-14

    申请人： Lixiao WANG ,  Urotronic, Inc.

    发明人： Lixiao Wang

    IPC分类号： A61L29/16 ,  A61L29/08

    摘要： Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.

    摘要翻译： 本发明的实施方案提供了一种用于治疗诸如良性前列腺增生（BPH），尿道狭窄，输尿管狭窄，前列腺癌，食管狭窄，窦狭窄，胆道狭窄，哮喘和慢性阻塞性肺病的非血管性体腔狭窄的方法 COPD）。 该方法优选通过药物涂覆的气囊导管递送抗炎和抗增殖药物（雷帕霉素或紫杉醇及其类似物）和一种或多种添加剂。