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公开(公告)号：US20240334935A1
公开(公告)日：2024-10-10
申请号：US18293475
申请日：2022-08-02
Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.
Inventor： Mari SHIOZAKI , Akifumi HAGI , Hisae NISHIOKA
CPC classification number: A01N47/44 , A01N25/02 , A01P1/00 , A61L24/00 , A61L24/0015 , A61L2300/206 , A61L2300/404 , A61L2300/802
Abstract: The object of the present invention is to provide an antiseptic composition that can reduce the risk of an incise drape coming off from the skin, without adversely affecting microbicidal activity, even when the incise drape is affixed to skin surface after application of the antiseptic composition, and/or exerts more effective microbicidal activity. A composition comprising a microbicide and a sugar alcohol is used as the antiseptic composition.
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2.发明公开公开(公告)号：US20240325108A1
公开(公告)日：2024-10-03
申请号：US18194007
申请日：2023-03-31
Applicant: C.R. Bard, Inc.
Inventor： Aaron Blank , Hiep Q. Do
CPC classification number: A61B90/39 , A61L31/041 , A61L31/145 , A61L31/146 , A61B2090/3908 , A61B2090/3925 , A61B2090/3995 , A61L2300/802 , A61L2400/04 , A61L2420/02
Abstract: A tissue marker is provided having a permanent portion and a biodegradable portion. The permanent portion includes a material detectable by an imaging modality. The biodegradable portion surrounds the permanent portion. The biodegradable portion includes a polymer body, a coating, and a plurality of distinct structures dispersed in the polymer body. The coating covers an outer surface of the polymer body. Each of the distinct structures include an outer shell designed to open upon the application of focused ultrasound to release a therapeutic agent within the outer shell into the polymer body. Therapeutic agents may be introduced into the biodegradable portion of the tissue marker after a period of time after introduction of the tissue marker into the tissue. In addition, methods of fabricating a three-layer tissue marker are provided.
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3.发明公开公开(公告)号：US20240226376A9
公开(公告)日：2024-07-11
申请号：US18483493
申请日：2023-10-09
CPC classification number: A61L27/26 , A61L27/52 , A61L2300/252 , A61L2300/412 , A61L2300/802 , A61L2430/34
Abstract: The present invention relates to a transdermal photocuring forming hydrogel with biological activity. The hydrogel can release recombinant collagen with biological activity, the recombinant collagen includes a sequence as shown in SEQ ID No. 1, an amino acid sequence of the recombinant collagen includes N basic repetitive units, and each basic repetitive unit includes n1 of the following characteristic amino acid sequences: “G-Xaa1-Xaa2-G-E-Xaa3”; the 3′ end and the 5′ end of the basic repetitive unit are connected to form the above characteristic amino acid sequence. The recombinant collagen provided by the present invention has relatively obvious integrin binding activity, and has the effects of promoting cell adhesion, proliferation and differentiation. The hydrogel of the present invention has good biocompatibility and stable quality, which can be cured and formed in situ in a transdermal photo-crosslinking manner after injection, with simple, convenient and controllable operation.
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公开(公告)号：US20240181136A1
公开(公告)日：2024-06-06
申请号：US18551535
申请日：2022-03-25
Inventor： Jeanne E. PEMBERTON , Laurel L. KEGEL , Yu-Cheng WANG
CPC classification number: A61L27/52 , A61L27/54 , A61L2300/232 , A61L2300/602 , A61L2300/802
Abstract: The present invention provides a biocompatible low molecular weight (LMW) hydrogel having a high storage modulus that comprises water and thioglycolipid. The invention also provides a carrier material and an article of manufacture comprising said LMW hydrogel. The present invention also provides methods for producing and using the same. The LMW hydrogels are made of aggregates of thioglycolipid via noncovalent interactions.
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公开(公告)号：US11998656B2
公开(公告)日：2024-06-04
申请号：US17549131
申请日：2021-12-13
Applicant: GUANGZHOU BIOSEAL BIOTECH CO. LTD.
Inventor： Shuang Chen , Yufu Li , Dengmin Feng , Xiang Wan
IPC: A61L24/10 , A61K9/16 , A61K31/717 , A61K38/36 , A61K38/48 , A61K47/18 , A61L24/00 , A61L24/02 , A61L24/08 , C08J3/12
CPC classification number: A61L24/108 , A61K9/16 , A61K9/1611 , A61K9/1682 , A61K31/717 , A61K38/363 , A61K38/4833 , A61K47/18 , A61L24/0042 , A61L24/02 , A61L24/08 , A61L24/106 , C08J3/12 , C12Y304/21005 , A61L2300/232 , A61L2300/252 , A61L2300/418 , A61L2300/802 , A61L2400/04 , A61L2430/36 , C08J2301/02 , C08J2389/00
Abstract: The present invention is directed to hemostatic compositions comprising at least partially integrated agglomerated ORC fibers, fibrinogen, and thrombin and methods of forming a powdered hemostatic composition, comprising the steps of: forming a suspension of a mixture comprising particles of fibrinogen, thrombin, ORC fibers in a non-aqueous low boiling solvent; spraying the suspension through a nozzle onto a substrate, allowing the non-aqueous solvent to evaporate; separating from the substrate and sieving the composition.
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Patent Agency Ranking
6.发明公开公开(公告)号：US20240100216A1
公开(公告)日：2024-03-28
申请号：US18263145
申请日：2022-03-22
Applicant: MÖLNLYCKE HEALTH CARE AB
Inventor： Erik Carlsson
IPC: A61L15/44
CPC classification number: A61L15/44 , A61L2300/104 , A61L2300/404 , A61L2300/606 , A61L2300/802 , A61L2420/02
Abstract: Described are fiber materials with improved properties and a process for producing the same. The fiber materials have, at the same time, improved mechanical and antimicrobial properties as well as improved wear properties (i.e. “softness”), without the occurrence of severe discoloration imparted by the antimicrobial agent added.
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公开(公告)号：US20240066180A1
公开(公告)日：2024-02-29
申请号：US18453663
申请日：2023-08-22
Applicant: Keranetics, Inc.
Inventor： Luke Burnett
IPC: A61L26/00
CPC classification number: A61L26/0066 , A61L26/008 , A61L2300/25 , A61L2300/802
Abstract: Described herein are therapeutic compositions comprising a wound healing agent such as keratin, and a bitterant, that can be used for skin care applications or to treat and heal wounds in veterinary medicine while preventing licking without the use of an Elizabethan collar.
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公开(公告)号：US20240000996A1
公开(公告)日：2024-01-04
申请号：US18463056
申请日：2023-09-07
Applicant: Zetagen Therapeutics, Inc.
Inventor： Bryan S. Margulies , Nikhil A. Thakur
IPC: A61L27/12 , A61L27/54 , A61K31/485 , A61L27/04 , A61L27/24
CPC classification number: A61L27/12 , A61L27/54 , A61K31/485 , A61L27/042 , A61L27/24 , A61L2300/602 , A61L2300/204 , A61K2300/00 , A61L2300/802 , A61L2430/38 , A61L2430/02
Abstract: A bone graft composition comprising a calcium phosphate putty is provided. A method of repairing a bone defect in a patient by applying the bone graft composition is also provided.
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公开(公告)号：US20230381371A1
公开(公告)日：2023-11-30
申请号：US18033371
申请日：2022-03-11
Inventor： Qian CHEN , Litao FAN , Chengyu ZHANG , Yong YOU , Yajian WU
IPC: A61L26/00
CPC classification number: A61L26/008 , A61L26/0066 , A61L26/0052 , A61L2300/204 , A61L2300/216 , A61L2300/602 , A61L2300/802
Abstract: A polymer hydrogel with a slow-release function, and a preparation method and use thereof are provided. The polymer hydrogel includes the following components in mass percentage contents: 0.01% to 15% of an active ingredient, 0.01% to 15% of an ion inhibitor, 0.01% to 1% of a crosslinking agent, 0.1% to 10% of a polymer resin, 10% to 35% of a solvent, 0.1% to 15% of a skin-touch regulator, 10% to 55% of deionized water, 0.1% to 3% of an appearance modifier, 0.01% to 1% of a crosslinking regulator, 0.01% to 1% of a preservative, and 0.01% to 5% of a transdermal absorption enhancer. The polymer hydrogel prepared by the present disclosure has excellent skin adaptability and skin permeability, long drug slow-release time, and excellent bioadhesion to the skin, and can be repeatedly peeled off without residue.
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公开(公告)号：US20230364016A1
公开(公告)日：2023-11-16
申请号：US18222825
申请日：2023-07-17
Applicant: Biotronik AG
Inventor： Ronald E Betts
IPC: A61K9/00 , A61K31/436 , A61L29/16 , A61L29/08 , C08L89/00
CPC classification number: A61K9/0085 , A61K31/436 , A61L29/16 , A61L29/085 , C08L89/00 , A61L2420/08 , A61L2300/416 , A61L2300/802 , A61L2300/608
Abstract: This application relates generally to the field of minimally invasive delivery of therapeutic agents. Specifically, the present invention provides for materials and methods directed to minimally invasive, targeted delivery of agents such as drugs, penetrants, blood barrier augmentation agents or other compounds to certain localized brain regions through the use of delivery balloon catheters.
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