公开(公告)号：US20240350635A1

公开(公告)日：2024-10-24

申请号：US18757012

申请日：2024-06-27

申请人： AIM Targeted Therapies, Inc.

发明人： Glenn ABRAHMSOHN

IPC分类号： A61K47/02 ,  A61K8/19 ,  A61K8/20 ,  A61K8/22 ,  A61K8/40 ,  A61K8/43 ,  A61K8/46 ,  A61K8/49 ,  A61K8/86 ,  A61K9/00 ,  A61K9/06 ,  A61K31/155 ,  A61K31/18 ,  A61K33/40 ,  A61K47/16 ,  A61K47/26 ,  A61K47/32 ,  A61K47/42 ,  A61L15/18 ,  A61L15/20 ,  A61L15/44 ,  A61L29/08 ,  A61L29/10 ,  A61L29/16 ,  A61L31/08 ,  A61L31/16 ,  A61Q11/00 ,  A61Q17/00

CPC分类号： A61K47/02 ,  A61K8/19 ,  A61K8/20 ,  A61K8/22 ,  A61K8/40 ,  A61K8/43 ,  A61K8/466 ,  A61K8/498 ,  A61K8/86 ,  A61K9/0014 ,  A61K9/0053 ,  A61K9/06 ,  A61K31/155 ,  A61K31/18 ,  A61K33/40 ,  A61K47/16 ,  A61K47/26 ,  A61K47/32 ,  A61K47/42 ,  A61L15/18 ,  A61L15/20 ,  A61L15/44 ,  A61L29/08 ,  A61L29/106 ,  A61L29/16 ,  A61L31/08 ,  A61L31/088 ,  A61L31/16 ,  A61Q11/00 ,  A61Q17/005 ,  A61L2300/202 ,  A61L2300/206 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2420/00

摘要： Therapeutic compositions, primarily for topical application, and methods of making and using the composition. Pharmaceutical compositions formulated for specific forms of administration are also provided.

公开(公告)号：US12059466B2

公开(公告)日：2024-08-13

申请号：US17360968

申请日：2021-06-28

申请人： AIM Targeted Therapies, Inc.

发明人： Glenn Abrahmsohn

IPC分类号： A61K47/02 ,  A61K8/19 ,  A61K8/20 ,  A61K8/22 ,  A61K8/40 ,  A61K8/43 ,  A61K8/46 ,  A61K8/49 ,  A61K8/86 ,  A61K9/00 ,  A61K9/06 ,  A61K31/155 ,  A61K31/18 ,  A61K33/40 ,  A61K47/16 ,  A61K47/26 ,  A61K47/32 ,  A61K47/42 ,  A61L15/18 ,  A61L15/20 ,  A61L15/44 ,  A61L29/08 ,  A61L29/10 ,  A61L29/16 ,  A61L31/08 ,  A61L31/16 ,  A61Q11/00 ,  A61Q17/00

CPC分类号： A61K47/02 ,  A61K8/19 ,  A61K8/20 ,  A61K8/22 ,  A61K8/40 ,  A61K8/43 ,  A61K8/466 ,  A61K8/498 ,  A61K8/86 ,  A61K9/0014 ,  A61K9/0053 ,  A61K9/06 ,  A61K31/155 ,  A61K31/18 ,  A61K33/40 ,  A61K47/16 ,  A61K47/26 ,  A61K47/32 ,  A61K47/42 ,  A61L15/18 ,  A61L15/20 ,  A61L15/44 ,  A61L29/08 ,  A61L29/106 ,  A61L29/16 ,  A61L31/08 ,  A61L31/088 ,  A61L31/16 ,  A61Q11/00 ,  A61Q17/005 ,  A61L2300/202 ,  A61L2300/206 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2420/00 ,  A61K31/155 ,  A61K2300/00 ,  A61K31/18 ,  A61K2300/00

摘要： Therapeutic compositions, primarily for topical application, and methods of making and using the composition. Pharmaceutical compositions formulated for specific forms of administration are also provided.

公开(公告)号：US20190201681A1

公开(公告)日：2019-07-04

申请号：US16227651

申请日：2018-12-20

申请人： Pursuit Vascular, Inc.

发明人： Robert J. Ziebol ,  Keith J. Modert ,  Matthew Case Ziebol

IPC分类号： A61M39/20 ,  A61B50/30 ,  A61L2/18 ,  A61M25/00 ,  A61L29/16 ,  A61L31/16 ,  A61L29/08

CPC分类号： A61M39/20 ,  A61B50/30 ,  A61B2050/3008 ,  A61L2/186 ,  A61L29/08 ,  A61L29/16 ,  A61L31/16 ,  A61L2202/24 ,  A61L2300/206 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2420/02 ,  A61M1/3661 ,  A61M5/001 ,  A61M25/0017 ,  A61M25/002 ,  A61M25/0043 ,  A61M39/162 ,  A61M39/165 ,  A61M2025/0018 ,  A61M2025/0019 ,  A61M2025/0056 ,  A61M2209/10

摘要： Systems, methods, and articles for providing an antimicrobial composition to the proximal elements of a trans-dermal catheter and into the lumen of the transdermal catheter are disclosed. In an embodiment, an antimicrobial composition on surface a cap element transfers antimicrobial to the proximal end of the transdermal catheter. The system comprises an elongate member configured for insertion into a lumen of a catheter, the elongate member containing an antimicrobial.

公开(公告)号：US20190160209A1

公开(公告)日：2019-05-30

申请号：US16262981

申请日：2019-01-31

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： VINOD P. MENON ,  JOSEPH D. RULE ,  RICHARD B. ROSS ,  DEENA M. CONRAD-VLASAK ,  KATIE F. WLASCHIN

IPC分类号： A61L31/16 ,  A61L15/46 ,  A61L31/14 ,  A61L15/44 ,  A61L15/58

CPC分类号： A61L31/16 ,  A61L15/44 ,  A61L15/46 ,  A61L15/58 ,  A61L31/14 ,  A61L2300/206 ,  A61L2300/404

摘要： Compositions containing chlorhexidine gluconate solubilized in hydrophobic vehicles are described. Resin systems containing such chlorhexidine gluconate compositions, including adhesives and articles incorporating such resin systems, including medical articles such as drapes are also described.

公开(公告)号：US09981069B2

公开(公告)日：2018-05-29

申请号：US14564920

申请日：2014-12-09

申请人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

发明人： Shanta Modak ,  Arnab Kumar Ghosh ,  Ronald Citron ,  Santoshkumar Hanmantrao Dongre ,  Nayana Baiju

IPC分类号： A61L29/16 ,  A61L29/08 ,  A61L27/54 ,  A61L26/00 ,  A61L27/26 ,  A01N47/44 ,  A61L15/46 ,  A01N25/10 ,  A01N31/02 ,  A01N37/36

CPC分类号： A61L29/16 ,  A01N25/10 ,  A01N31/02 ,  A01N37/36 ,  A01N47/44 ,  A01N59/16 ,  A61L15/46 ,  A61L26/0052 ,  A61L26/0066 ,  A61L27/26 ,  A61L27/54 ,  A61L29/085 ,  A61L2300/104 ,  A61L2300/206 ,  A61L2300/216 ,  A61L2300/404 ,  A61L2420/06

摘要： The present invention relates to methods and compositions for rendering a surface resistant to bio-film formation by a combination of an alkanediol and an antimicrobial agent (and, optionally, an organic hydroxy acid). The invention provides for compositions which may be used to render surfaces bio-film resistant, articles having bio-film resistant surfaces, and methods for their preparation. The present invention may be advantageously applied to medical articles as well as articles used in non-medical contexts, such as child care or food preparation.

公开(公告)号：US20180015197A1

公开(公告)日：2018-01-18

申请号：US15717366

申请日：2017-09-27

申请人： BRIGHTWAKE LIMITED

发明人： Stephen COTTON

IPC分类号： A61L15/40 ,  A61F13/00 ,  A61F13/02 ,  A61F13/20 ,  A61L15/22 ,  B32B5/24 ,  A61L15/60 ,  B32B5/02 ,  D04B21/16 ,  D02G3/44 ,  D02G3/04 ,  A61L15/42 ,  A61L15/44

CPC分类号： A61L15/40 ,  A61F13/00012 ,  A61F13/00021 ,  A61F13/00063 ,  A61F13/00068 ,  A61F13/0209 ,  A61F13/2005 ,  A61F2013/00174 ,  A61F2013/00229 ,  A61F2013/00242 ,  A61F2013/00536 ,  A61F2013/0054 ,  A61F2013/0091 ,  A61L15/225 ,  A61L15/425 ,  A61L15/44 ,  A61L15/60 ,  A61L2300/206 ,  B32B5/024 ,  B32B5/026 ,  B32B5/245 ,  B32B2262/06 ,  B32B2556/00 ,  D02G3/04 ,  D02G3/448 ,  D04B21/16 ,  D10B2201/20 ,  D10B2509/022 ,  C08L1/02 ,  C08L5/00

摘要： Described herein are wound dressings, methods for their production and components for use therein. Described herein are a knitted structure including a blend of gelling fibres and non-gelling fibres wherein the yarn includes at least 50% w/w gelling fibres, a three-dimensional textile material including gelling fibres, and a yarn including a blend of gelling and non-gelling fibres which may be used in their production, the knitted structure and three-dimensional textile material being suitable for use as wound dressings or as components of composite wound dressings. The wound dressings may be adapted for use in negative pressure wound therapy (NPWT). It has been found that the incorporation of gel-forming fibres provides a material which has a high absorbency, enabling good transfer of exudates away from a wound, which retains structural integrity, and which is non-adherent and easily removed from the wound.

公开(公告)号：US20170304815A1

公开(公告)日：2017-10-26

申请号：US15509834

申请日：2015-09-09

申请人： David John VACHON ,  Scott Frithjof NORDAL ,  Dana Christopher WALTERS ,  IASIS MOLECULAR SCIENCES

发明人： David J. VACHON

IPC分类号： B01J45/00 ,  A01N25/10 ,  A01N25/16 ,  A01N33/12 ,  A01N41/04 ,  A01N41/12 ,  A01N43/40 ,  A01N59/00 ,  A01N59/16 ,  A61H19/00 ,  A61K31/14 ,  A61K31/155 ,  A61K31/616 ,  A61K47/58 ,  G01N33/18 ,  C09J183/04 ,  C09J11/08 ,  C09J9/00 ,  C09D201/00 ,  C09D5/16 ,  C09D5/14 ,  C08L83/04 ,  C08L75/04 ,  C08L63/00 ,  C08L57/06 ,  C08L23/12 ,  C08J9/36 ,  C08J3/12 ,  B65D65/42 ,  B65D65/40 ,  B01J39/20 ,  A61L29/16 ,  A61L29/08 ,  A61L27/54 ,  A61L27/18 ,  A61L26/00 ,  A61L15/58 ,  A61L15/44 ,  A61L15/24 ,  A61K33/38 ,  G01N33/24

CPC分类号： B01J45/00 ,  A01N25/10 ,  A01N25/16 ,  A01N33/12 ,  A01N41/04 ,  A01N41/12 ,  A01N43/40 ,  A01N59/00 ,  A01N59/16 ,  A61H19/44 ,  A61K31/14 ,  A61K31/155 ,  A61K31/616 ,  A61K33/38 ,  A61K47/585 ,  A61L15/24 ,  A61L15/44 ,  A61L15/46 ,  A61L15/58 ,  A61L26/0066 ,  A61L26/0085 ,  A61L27/18 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/11 ,  A61L2300/206 ,  A61L2300/208 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/43 ,  A61L2300/606 ,  B01J39/19 ,  B01J39/20 ,  B01J41/14 ,  B65D65/40 ,  B65D65/42 ,  C08J3/12 ,  C08J9/365 ,  C08J2205/05 ,  C08J2325/02 ,  C08J2325/08 ,  C08J2375/04 ,  C08J2425/02 ,  C08J2425/08 ,  C08L23/12 ,  C08L57/06 ,  C08L63/00 ,  C08L75/04 ,  C08L83/04 ,  C09D5/14 ,  C09D5/1637 ,  C09D201/00 ,  C09J9/00 ,  C09J11/08 ,  C09J183/04 ,  G01N33/18 ,  G01N33/24 ,  G01N2033/245 ,  A01N47/44 ,  A01N59/20

摘要： Biologically activated ion-exchange polymer salts are made by exchanging biologically active ionic agents onto ion-exchange polymers. The activated polymers are uniquely surface active and stable to thermal degradation and chemical and other forms of decomposition. The activated ion-exchange polymer salts may be processed and combined with polymer precursors using novel methods and materials to produce stable, biologically activated polymer composites, including antimicrobial and antifouling polymer composites.

公开(公告)号：US20170151314A1

公开(公告)日：2017-06-01

申请号：US15414182

申请日：2017-01-24

申请人： ROCHAL INDUSTRIES, LLC

发明人： Joseph Charles Salamone ,  Kelly Xiaoyu Chen Leung ,  Ann Beal Salamone ,  Katelyn Elizabeth Reilly

IPC分类号： A61K38/47 ,  A61K47/14 ,  A61K47/06 ,  A61K47/10 ,  A61K38/54 ,  A61K9/06

CPC分类号： A61K38/47 ,  A61K9/06 ,  A61K38/465 ,  A61K38/4873 ,  A61K38/54 ,  A61K45/06 ,  A61K47/06 ,  A61K47/10 ,  A61K47/14 ,  A61L15/38 ,  A61L15/44 ,  A61L26/0047 ,  A61L26/0066 ,  A61L2300/206 ,  A61L2300/254 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/45 ,  C12Y302/01 ,  C12Y302/01001 ,  C12Y302/01002 ,  C12Y304/22032 ,  C12Y304/24007 ,  A61K2300/00

摘要： A debridement enzyme for necrotic tissue is described that is not dependent upon proteolytic enzymatic activity but instead utilizes the amylase family of enzymes. The amylases (α-, β-, γ-amylase) are noted for the cleavage of the α-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that α-amylase is effective in the debridement of devitalized tissue.

公开(公告)号：US09649411B2

公开(公告)日：2017-05-16

申请号：US15086860

申请日：2016-03-31

申请人： Becton, Dickinson and Company

发明人： Minh Quang Hoang

IPC分类号： A61K9/14 ,  A61L29/16 ,  A01N31/02 ,  A61K31/045 ,  A61K31/135 ,  A61K31/155 ,  A61K31/205 ,  A61K31/496 ,  A61K31/60 ,  A61K31/612 ,  A61K33/38 ,  A61K45/06 ,  A61K47/10 ,  A61K47/32 ,  A61K47/34 ,  A61L29/08 ,  A61L29/14 ,  A61L29/10 ,  A61L2/00 ,  A61L2/18 ,  A61M25/00

CPC分类号： A61L29/16 ,  A01N31/02 ,  A61K31/045 ,  A61K31/135 ,  A61K31/155 ,  A61K31/198 ,  A61K31/205 ,  A61K31/496 ,  A61K31/60 ,  A61K31/612 ,  A61K33/38 ,  A61K45/06 ,  A61K47/10 ,  A61K47/32 ,  A61K47/34 ,  A61K2300/00 ,  A61L2/0088 ,  A61L2/186 ,  A61L29/08 ,  A61L29/085 ,  A61L29/106 ,  A61L29/14 ,  A61L2202/24 ,  A61L2300/206 ,  A61L2300/21 ,  A61L2300/214 ,  A61L2300/216 ,  A61L2300/404 ,  A61L2300/42 ,  A61M2025/0056 ,  A01N25/10 ,  A01N25/30 ,  A01N47/44 ,  A01N2300/00 ,  C08L71/02

摘要： Antimicrobial compositions for use in locking catheters and other devices are provided. In some embodiments, the composition includes at least one alcohol, at least one biocidal agent which is not an alcohol, and one or more poloxamers; in other embodiments, the composition comprises at least one poloxamer and at least one alcohol. The composition can provide long-lasting antimicrobial activity. Methods of using the composition are also provided.

公开(公告)号：US20170112691A1

公开(公告)日：2017-04-27

申请号：US15397250

申请日：2017-01-03

申请人： Medline Industries, Inc.

发明人： Min Yao ,  Daniel B. Love ,  Amin Setoodeh ,  Debashish Chakravarthy

IPC分类号： A61F13/84 ,  B32B38/04 ,  B32B27/32 ,  A61F13/511 ,  A61F13/15 ,  A61L15/46 ,  A61F13/53 ,  B32B37/18 ,  B32B27/06

CPC分类号： A61F13/8405 ,  A61F13/15723 ,  A61F13/15804 ,  A61F13/51113 ,  A61F13/53 ,  A61F2013/530481 ,  A61F2013/8414 ,  A61L15/46 ,  A61L2300/206 ,  A61L2300/404 ,  B32B27/065 ,  B32B27/32 ,  B32B33/00 ,  B32B37/182 ,  B32B38/04 ,  B32B2307/7145 ,  B32B2307/726 ,  B32B2307/7265 ,  B32B2323/10 ,  B32B2555/02

摘要： According to one embodiment, an absorbent article includes a moisture-impervious outer layer, an inner layer substantially co-extensive with the outer layer, and an absorbent layer interposed between the outer layer and the inner layer. The inner layer is treated with at least one antimicrobial booster. The absorbent layer is treated with at least one antimicrobial agent.