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    Drug Coated Balloon Catheters for Nonvascular Strictures
    1.
    发明申请
    Drug Coated Balloon Catheters for Nonvascular Strictures 审中-公开
    用于非血管狭窄的药物涂层气球导管

    公开(公告)号：US20150273117A1

    公开(公告)日：2015-10-01

    申请号：US14438327

    申请日：2013-10-14

    申请人： Lixiao WANG ,  Urotronic, Inc.

    发明人： Lixiao Wang

    IPC分类号： A61L29/16 ,  A61L29/08

    摘要： Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.

    摘要翻译： 本发明的实施方案提供了一种用于治疗诸如良性前列腺增生（BPH），尿道狭窄，输尿管狭窄，前列腺癌，食管狭窄，窦狭窄，胆道狭窄，哮喘和慢性阻塞性肺病的非血管性体腔狭窄的方法 COPD）。 该方法优选通过药物涂覆的气囊导管递送抗炎和抗增殖药物（雷帕霉素或紫杉醇及其类似物）和一种或多种添加剂。

    Drug releasing coatings for medical devices
    5.
    发明授权
    Drug releasing coatings for medical devices 有权

    公开(公告)号：US08244344B2

    公开(公告)日：2012-08-14

    申请号：US13272432

    申请日：2011-10-13

    申请人： Lixiao Wang

    发明人： Lixiao Wang

    IPC分类号： A61M37/00 ,  A61M25/10 ,  A61B18/20

    CPC分类号： A61L31/16 ,  A61K31/337 ,  A61K31/436 ,  A61L29/16 ,  A61L31/08 ,  A61L2300/416 ,  A61L2300/80 ,  A61L2300/802 ,  A61K2300/00

    摘要： The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.

    Catheter having an improved balloon-to-catheter bond
    6.
    发明授权
    Catheter having an improved balloon-to-catheter bond 有权
    导管具有改善的气球与导管接合

    公开(公告)号：US07914486B2

    公开(公告)日：2011-03-29

    申请号：US10764405

    申请日：2004-01-23

    申请人： John Chen ,  Nie Tang ,  Ed Parsonage ,  Paul Miller ,  Lixiao Wang

    发明人： John Chen ,  Nie Tang ,  Ed Parsonage ,  Paul Miller ,  Lixiao Wang

    IPC分类号： A61M29/00

    CPC分类号： A61L29/04 ,  A61L29/06 ,  A61M25/10 ,  A61M25/1034 ,  C08L77/00 ,  C08L67/02

    摘要： A balloon catheter assembly includes a first tubular member with a proximal portion and a distal portion and a lumen extending between the proximal portion and the distal portion. A balloon has a proximal waist length, a distal waist length and an expandable region therebetween disposed about the distal portion. A tie layer is disposed between the proximal waist length or distal waist length and the first tubular member. The tie layer comprises a polyester polymer and a polyamide polymer.

    摘要翻译： 球囊导管组件包括具有近端部分和远端部分的第一管状部件和在近端部分和远端部分之间延伸的内腔。 气球具有近端腰部长度，远端腰围长度和围绕远侧部分设置的可扩张区域。 连接层设置在近端腰部长度或远端腰部长度与第一管状部件之间。 连结层包含聚酯聚合物和聚酰胺聚合物。