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公开(公告)号：US12109335B2
公开(公告)日：2024-10-08
申请号：US16811636
申请日：2020-03-06
IPC分类号： A61K9/16 , A61B5/00 , A61B8/00 , A61B8/12 , A61L31/02 , A61L31/06 , A61L31/12 , A61L31/14 , C08G77/00 , C08L83/04 , G01S15/89 , G10K11/30
CPC分类号： A61L31/129 , A61B5/0095 , A61B8/12 , A61B8/4444 , A61L31/028 , A61L31/06 , A61L31/128 , A61L31/14 , C08G77/70 , C08L83/04 , G01S15/8906 , G10K11/30 , C08L2205/025 , C08L2205/03
摘要： A composition for an acoustic wave probe, containing the following ingredients (A) to (D): (A) a linear polysiloxane having a vinyl group; (B) a linear polysiloxane having two or more Si—H groups in a molecular chain; (C) a polysiloxane resin; and (D) surface-treated silica particles having an average primary particle diameter more than 16 nm and less than 100 nm, as well as, a silicone resin for an acoustic wave probe, an acoustic wave probe, an ultrasound probe, an acoustic wave measurement apparatus, an ultrasound diagnostic apparatus, a photoacoustic wave measurement apparatus, and an ultrasound endoscope, using the composition for an acoustic wave probe.
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2.发明公开公开(公告)号：US20240299626A1
公开(公告)日：2024-09-12
申请号：US18549437
申请日：2022-03-08
发明人： Dong Keun HAN , Kyoung-Won KO , So-Yeon PARK
IPC分类号： A61L27/44 , A61L27/10 , A61L27/36 , A61L27/54 , A61L27/56 , A61L27/58 , A61L31/00 , A61L31/02 , A61L31/12 , A61L31/14 , A61L31/16
CPC分类号： A61L27/446 , A61L27/10 , A61L27/3633 , A61L27/54 , A61L27/56 , A61L27/58 , A61L31/005 , A61L31/026 , A61L31/128 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/258 , A61L2400/18
摘要： Provided are a biodegradable polymer scaffold including bioactive materials and methods of manufacturing the same. The biodegradable polymer scaffold, preventing inflammatory responses caused by acidic substances produced during a degradation process, has easily controllable mechanical strength, and includes bioactive materials derived from cells of target tissues, and thus may induce tissue regeneration more effectively.
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3.发明公开公开(公告)号：US20240293150A1
公开(公告)日：2024-09-05
申请号：US18573512
申请日：2022-06-24
申请人： Wanliang Shan
发明人： Wanliang Shan
CPC分类号： A61B17/3421 , A61B10/04 , A61B34/30 , A61L31/128 , A61L31/14 , A61B2010/045 , A61B2017/00318 , A61B2017/00867 , A61B2017/00964 , A61B2034/301
摘要： A steerable robotic needle formed from a compliant wire that is surrounded by an inner layer having one or more tunable regions positioned in predetermined locations and an inert region extending over the rest of the wire. The tunable region changes stiffness in response to an external trigger, such as heating via electrical energy, so that the needle can bend more readily in the predetermined location. The inner layer may be encapsulated in an elastomeric tube to prevent heat from reaching the surrounding environment. The resulting change in stiffness allows the needle to perform maneuvers in a body that require a larger curvature.
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公开(公告)号：US20240139386A1
公开(公告)日：2024-05-02
申请号：US18404563
申请日：2024-01-04
申请人： OrthoMedex LLC
发明人： James A. WALLS
IPC分类号： A61L31/08 , A61K9/70 , A61K33/38 , A61K33/42 , A61L24/00 , A61L27/42 , A61L27/44 , A61L31/02 , A61L31/12 , A61L31/14 , A61L31/16
CPC分类号： A61L31/086 , A61K9/70 , A61K33/38 , A61K33/42 , A61L24/0036 , A61L24/0042 , A61L24/0063 , A61L24/0068 , A61L24/0084 , A61L24/0089 , A61L27/425 , A61L27/427 , A61L27/446 , A61L31/022 , A61L31/082 , A61L31/123 , A61L31/124 , A61L31/127 , A61L31/128 , A61L31/146 , A61L31/148 , A61L31/16 , A61F2002/30677
摘要： A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic material having a desired particle size and solubility, and mixing the water-soluble inorganic material with at least one poorly-water-soluble or biodegradable matrix material. The matrix material, after it is mixed with the water-soluble inorganic material, is placed into the patient in proximity to tissue so that the water-soluble inorganic material dissolves at a predetermined rate to generate biologically desirable voids in the matrix material into which bone or other tissue can then grow.
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公开(公告)号：US11730866B2
公开(公告)日：2023-08-22
申请号：US17152165
申请日：2021-01-19
申请人： OSSIO, LTD
IPC分类号： A61L31/12 , A61L31/14 , A61B17/86 , A61L27/44 , A61L27/58 , A61F2/44 , A61L31/06 , A61L31/08 , A61F2/30
CPC分类号： A61L31/128 , A61B17/864 , A61B17/866 , A61F2/447 , A61F2/4455 , A61L27/446 , A61L27/58 , A61L31/06 , A61L31/08 , A61L31/148 , A61F2002/30062 , A61F2002/30593 , A61F2002/4495 , A61L31/128 , C08L67/04 , A61L27/446 , C08L67/04
摘要： A medical implant comprising a plurality of biocomposite layers, each layer comprising a polymer and a plurality of uni-directionally aligned continuous reinforcement fibers. The medical implant is suitable for load-bearing orthopedic implant applications and comprises one or more biocomposite materials where sustained mechanical strength and stiffness are critical for proper implant function.
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公开(公告)号：US20230145308A1
公开(公告)日：2023-05-11
申请号：US17896474
申请日：2022-08-26
发明人： Taichi ITO , Seiichi OHTA , Norihiro KOKUDO , Mitsuko ISAJI , Satoshi SHIMIZU
CPC分类号： A61B90/08 , A61L31/14 , A61L31/12 , A61L31/04 , A61L31/128 , A61L31/146 , A61B2090/0816 , A61L2420/08
摘要： An adhesion-preventing material having a high adhesion-preventing effect has been demanded. An adhesion-preventing material including a sterilized biocompatible sponge-like laminate, wherein the sponge-like laminate comprises a sponge-like first layer and a sponge-like second layer each of which is at least partially crosslinked with a curing agent and comprises a low-endotoxin alginic acid monovalent metal salt, the alginic acid monovalent metal salt in the first layer has a weight average molecular weight of 10,000 to 2,000,000, the alginic acid monovalent metal salt in the second layer has a weight average molecular weight of 1,000 to 1,000,000, the weight average molecular weights are measured by a GPC-MALS method after a decrosslinking treatment, and the weight average molecular weight of the alginic acid monovalent metal salt in the first layer is higher than that in the second layer.
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公开(公告)号：US09981074B1
公开(公告)日：2018-05-29
申请号：US15274704
申请日：2016-09-23
发明人： David Mills , Christen Boyer
IPC分类号： B82Y30/00 , A61L31/12 , A61L31/04 , A61L31/08 , A61L31/16 , C09C1/42 , C09C3/06 , C25D3/46 , C25D3/48 , C25D3/50 , C25D3/38
CPC分类号： A61L31/128 , A61L31/04 , A61L31/088 , A61L31/16 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/606 , A61L2400/12 , B82Y30/00 , C01P2004/13 , C01P2004/80 , C09C1/42 , C09C3/066 , C25D3/38 , C25D3/46 , C25D3/48 , C25D3/50
摘要： A method for forming metal nanoparticles on halloysite nanotubes. The method provides a water-based suspension solution containing about 0.002% to about 0.1% by weight of halloysite nanotubes. The suspension solution is maintained between about 2° C. and about 98° C. and under sufficient mixing that the nanotubes are maintained in substantially constant suspension. At least one positive and at least one negative metal electrode is positioned in the suspension solution, wherein the metal electrodes are at least 98% pure metal. A voltage is maintained across the electrodes of between about 10 and about 300 volts for a time sufficient to form metal ions on at least about 10% of a surface of the halloysite nanotubes.
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公开(公告)号：US20180140304A1
公开(公告)日：2018-05-24
申请号：US15575896
申请日：2016-05-25
发明人： Sayyeda Marziya Hasan , Jennifer Nicole Rodriguez , Pooja Singhal , Thomas Stephen Wilson , Duncan J. Maitland
CPC分类号： A61B17/12113 , A61B17/12131 , A61B17/1219 , A61B2017/00526 , A61B2017/00871 , A61B2090/3966 , A61L31/128 , A61L31/14 , A61L31/146 , A61L31/18 , A61L2400/12 , A61L2400/16 , A61M31/002 , C08L2201/12
摘要： The invention relates to radiopaque shape memory foam compositions and methods of using the compositions. In certain embodiments, the compositions are used in neurovascular occlusion applications.
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公开(公告)号：US09883865B2
公开(公告)日：2018-02-06
申请号：US14728393
申请日：2015-06-02
发明人： Toby Freyman , Joseph Lomakin , John Marini , Jennifer Mortensen , Adam Rago , Rany Busold , Upma Sharma , Gregory T. Zugates
IPC分类号： A61F2/06 , A61B17/12 , A61M37/00 , A61L31/06 , A61L31/12 , A61L31/14 , A61L24/00 , A61L24/04 , A61F2/07 , A61J1/20
CPC分类号： A61B17/12181 , A61B17/12113 , A61B17/12118 , A61B17/1214 , A61B2017/1205 , A61F2/07 , A61F2002/065 , A61F2002/077 , A61F2210/0085 , A61J1/2093 , A61L24/0036 , A61L24/0089 , A61L24/046 , A61L31/06 , A61L31/128 , A61L31/146 , A61L2300/60 , A61L2400/06 , A61M37/00 , C08L67/04 , C08L83/04
摘要： Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
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公开(公告)号：US20170246356A1
公开(公告)日：2017-08-31
申请号：US15523389
申请日：2015-12-28
申请人： Orahn PREISS-BLOOM , Ossio Ltd
CPC分类号： A61L31/128 , A61B17/864 , A61B17/866 , A61F2/4455 , A61F2/447 , A61F2002/30062 , A61F2002/4475 , A61F2002/4495 , A61L27/446 , A61L27/58 , A61L31/06 , A61L31/08 , A61L31/148 , C08L67/04
摘要： A medical implant comprising a plurality of layers, each layer comprising a polymer and a plurality of uni-directionally aligned continuous reinforcement fibers.
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