公开(公告)号：US20230414842A1

公开(公告)日：2023-12-28

申请号：US18463338

申请日：2023-09-08

申请人： Imam Abdulrahman Bin Faisal University

发明人： Khaled Fikry SALAMA ,  Arwa Abdulrahman AL THUMARI

IPC分类号： A61L31/08 ,  A61L31/02 ,  A61L31/12 ,  A61L31/16

CPC分类号： A61L31/088 ,  A61L31/028 ,  A61L31/124 ,  A61L31/16 ,  A61L2420/08 ,  A61L2400/12 ,  A61L2420/06

摘要： A health care and/or entertainment device protective film may be configured to contact human skin, e.g., to limit the transmission of infection by bacteria, fungi, protozoa, prions, and/or viruses. The film may be formed as a nanocomposite film including at least 75 wt. %, relative to total organic matrix weight, of polyethylene, silver particles, and TiO2 particles, wherein the silver particles and TiO2 particles are distributed within and/or on an outer surface of the polyethylene, wherein the silver particles have a size of 1 to 1,000 nm, and wherein the TiO2 particles have a size of 1 to 50 nm. Such films may be applied to health care and/or entertainment devices, including virtual reality googles.

公开(公告)号：US20230414841A1

公开(公告)日：2023-12-28

申请号：US18463335

申请日：2023-09-08

申请人： Imam Abdulrahman Bin Faisal University

发明人： Khaled Fikry SALAMA ,  Arwa Abdulrahman AL THUMARI

IPC分类号： A61L31/08 ,  A61L31/02 ,  A61L31/12 ,  A61L31/16

CPC分类号： A61L31/088 ,  A61L31/028 ,  A61L31/124 ,  A61L31/16 ,  A61L2420/08 ,  A61L2400/12 ,  A61L2420/06

摘要： A health care and/or entertainment device protective film may be configured to contact human skin, e.g., to limit the transmission of infection by bacteria, fungi, protozoa, prions, and/or viruses. The film may be formed as a nanocomposite film including at least 75 wt. %, relative to total organic matrix weight, of polyethylene, silver particles, and TiO2 particles, wherein the silver particles and TiO2 particles are distributed within and/or on an outer surface of the polyethylene, wherein the silver particles have a size of 1 to 1,000 nm, and wherein the TiO2 particles have a size of 1 to 50 nm. Such films may be applied to health care and/or entertainment devices, including virtual reality googles.

公开(公告)号：US11813007B2

公开(公告)日：2023-11-14

申请号：US16756271

申请日：2018-10-15

申请人： ARCTIC BIOMATERIALS OY

发明人： Harri Heino ,  Timo Lehtonen ,  Mikko Huttunen ,  Miika Lehtola

IPC分类号： A61B17/80 ,  A61L31/02 ,  A61L31/12 ,  A61L31/14 ,  A61B17/00 ,  A61B17/56

CPC分类号： A61B17/8061 ,  A61L31/026 ,  A61L31/124 ,  A61L31/148 ,  A61B2017/00004 ,  A61B2017/00526 ,  A61B2017/564

摘要： The present invention provides an orthopedic implant comprising a continuous reinforced composite filament in a freely predetermined fiber orientation in multiple continuous successive layers, wherein the continuous reinforced composite filament comprises a bioabsorbable polymer matrix and a continuous bioabsorbable reinforcing fiber or fiber bundle, and whereby the continuous bioabsorbable reinforcing fiber or fiber bundle of consecutive layers at least partly intermingles and/or intertwines forming a three dimensionally interlocked continuous fiber structure.

公开(公告)号：US20230250520A1

公开(公告)日：2023-08-10

申请号：US18007733

申请日：2021-06-24

申请人： W&M GMBH

发明人： Bernhard WEINBERG ,  Heinz MOITZI ,  Oliver RENK ,  Reinhard PIPPAN

IPC分类号： C22C38/00 ,  C22C33/02 ,  C22C23/00 ,  C22C18/00 ,  C22C1/04 ,  B22F3/105 ,  A61L31/12

CPC分类号： C22C38/002 ,  C22C33/0257 ,  C22C23/00 ,  C22C18/00 ,  C22C1/0483 ,  C22C1/0408 ,  B22F3/105 ,  A61L31/124 ,  B22F2003/1051 ,  B22F2202/13 ,  B22F2301/058 ,  B22F2301/30 ,  B22F2301/35 ,  B22F2999/00 ,  B22F2009/041

摘要： The present disclosure relates to a composite material, in particular a composite material of metals, a process for producing a composite material, and a medical device, in particular an implant, based on the composite material. The composite material comprises at least 5 vol-% of Fe and at least 1 vol-% of Mg or Zn, wherein the composite material comprises a Mg or Zn phase and an Fe phase, wherein the average size of the Mg or Zn phase in at least one dimension is less than 20 μm, in particular less than 10 μm. The medical device, in particular an implant, may be suitable for fixing of bone fractures (as well as fractions of a tendon or a ligament, etc.) and/or corrections and may be capable of exhibiting a targeted failure representing a complete paradigm shift in the treatment of bone fractures and the like.

公开(公告)号：US09700657B2

公开(公告)日：2017-07-11

申请号：US14337492

申请日：2014-07-22

申请人： HERAEUS MEDICAL GMBH ,  MEDIZINISCHE UNIVERSITÄT GRAZ

发明人： Klaus-Dieter Kühn ,  Annelie Weinberg ,  Peter Uggowitzer ,  Sebastian Vogt ,  Jörg Löffler

IPC分类号： A61L31/12 ,  A61F2/88 ,  A61L27/04 ,  A61L27/54 ,  A61L27/58 ,  A61L31/02 ,  A61L31/14 ,  A61L31/16 ,  C22C21/06

CPC分类号： A61L31/124 ,  A61F2/885 ,  A61F2220/005 ,  A61L27/047 ,  A61L27/54 ,  A61L27/58 ,  A61L31/028 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/206 ,  A61L2300/23 ,  A61L2300/406 ,  A61L2300/414 ,  C22C21/06

摘要： The invention relates to a composite material that comprises at least one magnesium component, whereby the magnesium component consists of pure magnesium or a magnesium-calcium alloy or a magnesium-calcium-X alloy, whereby X is another biodegradable element. The composite material also contains at least one organic anti-infective agent having a solubility in water at room temperature of less than 10 grams per liter.

公开(公告)号：US09592206B2

公开(公告)日：2017-03-14

申请号：US14168975

申请日：2014-01-30

申请人： AMxTek LLC

发明人： James A Walls

IPC分类号： A61F2/02 ,  A61K9/70 ,  A61K33/38 ,  A61K33/42 ,  A61L24/00 ,  A61L31/12 ,  A61L31/14 ,  A61L31/16 ,  A61L27/42 ,  A61L27/44 ,  A61F2/30 ,  A61F2/46 ,  A61L27/10 ,  A61B17/60 ,  A61B17/86 ,  A61F2/44

CPC分类号： A61L31/086 ,  A61B17/60 ,  A61B17/8625 ,  A61B17/866 ,  A61F2/28 ,  A61F2/32 ,  A61F2/4455 ,  A61F2/4644 ,  A61F2002/30013 ,  A61F2002/30032 ,  A61F2002/30034 ,  A61F2002/30036 ,  A61F2002/30677 ,  A61F2002/3068 ,  A61F2310/00329 ,  A61F2310/00359 ,  A61F2310/00928 ,  A61K9/70 ,  A61K33/38 ,  A61K33/42 ,  A61L24/0036 ,  A61L24/0042 ,  A61L24/0063 ,  A61L24/0068 ,  A61L24/0084 ,  A61L24/0089 ,  A61L27/10 ,  A61L27/425 ,  A61L27/427 ,  A61L27/446 ,  A61L31/022 ,  A61L31/082 ,  A61L31/123 ,  A61L31/124 ,  A61L31/127 ,  A61L31/128 ,  A61L31/146 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2400/18 ,  A61L2420/04 ,  A61L2430/02 ,  A61L2430/10 ,  A61L2430/34

摘要： A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic material having a desired particle size and solubility, and mixing the water-soluble inorganic material with at least one poorly-water-soluble or biodegradable matrix material. The matrix material, after it is mixed with the water-soluble inorganic material, is placed into the patient in proximity to tissue so that the water-soluble inorganic material dissolves at a predetermined rate to generate biologically desirable voids in the matrix material into which bone or other tissue can then grow.

摘要翻译： 通过选择至少一种具有所需粒径和溶解度的水溶性无机材料，并将水溶性无机材料与 至少一种难溶于水或可生物降解的基质材料。 将基质材料与水溶性无机材料混合后，在组织附近放置在患者体内，使得水溶性无机材料以预定的速率溶解，以在基质材料中产生生物上希望的空隙，骨中的骨骼 或其他组织然后可以生长。

公开(公告)号：US09446174B2

公开(公告)日：2016-09-20

申请号：US14456254

申请日：2014-08-11

申请人： Boston Scientific Scimed, Inc.

发明人： Jan Weber ,  Jacob Drew Edick

IPC分类号： A61L31/14 ,  A61F2/82 ,  B21C23/00 ,  C22F1/06 ,  A61L31/12

CPC分类号： A61L31/148 ,  A61F2/82 ,  A61L31/124 ,  A61L2400/12 ,  B21C23/001 ,  C22F1/06

摘要： A bioerodible endoprosthesis includes a composite including a matrix comprising a bioerodible magnesium alloy and a plurality of ceramic nanoparticles within the matrix. The bioerodible magnesium alloy has a microstructure including equiaxed Mg-rich solid solution-phase grains having an average grain diameter of less than or equal to 5 microns. The microstructure can be produced by one or more equal-channel high-strain processes.

摘要翻译： 生物腐蚀性内用假体包括包含基质的复合物，所述基质包含生物可腐蚀的镁合金和所述基质内的多个陶瓷纳米颗粒。 生物腐蚀性镁合金具有包括平均粒径小于或等于5微米的等轴Mg富集固相晶粒的微结构。 微结构可通过一个或多个等通道高应变过程产生。

公开(公告)号：US09089408B2

公开(公告)日：2015-07-28

申请号：US13764816

申请日：2013-02-12

申请人： Zhiyue Xu

发明人： Zhiyue Xu

IPC分类号： A61F2/02 ,  A61F2/08 ,  A61F2/28 ,  A61L27/58 ,  A61L27/42 ,  A61L31/12 ,  A61L31/14 ,  A61L17/06 ,  A61B17/68 ,  A61B17/00

CPC分类号： A61F2/02 ,  A61B17/68 ,  A61B2017/00004 ,  A61F2210/0004 ,  A61L17/06 ,  A61L27/427 ,  A61L27/58 ,  A61L31/124 ,  A61L31/148 ,  A61L2400/12

摘要： A medical implant includes a metal composite that contains a cellular nanomatrix having a metallic nanomatrix material and a metal matrix disposed in the cellular nanomatrix, the medical implant being configured to disintegrate in response to contact with a fluid. A method for repairing tissue includes disposing an implant in a patient, the implant including a metal composite which contains: a cellular nanomatrix having a metallic nanomatrix material; and a metal matrix disposed in the cellular nanomatrix; contacting tissue of the patient with the implant, the tissue being in need of repair; and non-operatively removing the implant to repair the tissue.

摘要翻译： 医疗植入物包括金属复合物，其包含具有金属纳米线材料的细胞纳米线性矩阵和设置在细胞纳米基质中的金属基体，所述医疗植入物构造成响应于与流体的接触而分解。 修复组织的方法包括将植入物放置在患者体内，所述植入物包括金属复合物，其包含：具有金属纳米线材料的细胞纳米线; 和设置在所述细胞纳米基质中的金属基质; 使患者的组织与植入物接触，所述组织需要修复; 并且非操作地移除植入物以修复组织。

公开(公告)号：US09039963B2

公开(公告)日：2015-05-26

申请号：US13650877

申请日：2012-10-12

申请人： Andrew E. Fisk ,  Anatolii Demchyshyn ,  Mykola Kuzmenko ,  Sergei Firstov ,  Leonid Kulak

发明人： Andrew E. Fisk ,  Anatolii Demchyshyn ,  Mykola Kuzmenko ,  Sergei Firstov ,  Leonid Kulak

IPC分类号： C22C14/00 ,  B22D25/06 ,  A61L31/12 ,  B22D7/00 ,  B22D21/00 ,  A61L31/02

CPC分类号： A61L31/124 ,  A61L31/022 ,  B22D7/005 ,  B22D21/005 ,  B22D25/06 ,  C22C14/00

摘要： A titanium based, ceramic reinforced alloy ingot for use in producing medical implants. An ingot is formed from an alloy having comprising from about 5 to about 35 wt. % niobium, from about 0.5 to about 3.5 wt. % silicon, and from about 61.5 to about 94.5 wt. % of titanium. The alloy has a hexagonal crystal lattice α phase of from about 20 vol % to about 70 vol %, and a cubic body centered β crystal lattice phase of from about 30 vol. % to about 80 vol. %. The ingot has an ultimate tensile strength of about 940 MPa or more, and a Young's modulus of about 150 GPa or less. A molten substantially uniform admixture of a niobium, silicon, and titanium alloy is formed, cast into a shape, and cooled into an ingot. The ingot may then be formed into a medical implant and optionally annealed.

摘要翻译： 用于生产医疗植入物的钛基陶瓷增强合金锭。 锭由合金形成，该合金包含约5至约35重量％ ％铌，约0.5-约3.5wt。 ％硅，和约61.5至约94.5wt。 ％的钛。 该合金具有约20体积％至约70体积％的六方晶系晶格α相和以体积为中心的立方体。 晶格相约为30体积％。 ％至约80体积％ ％。 该锭的极限拉伸强度为约940MPa以上，杨氏模量为约150GPa以下。 形成熔融的大体均匀的铌，硅和钛合金的混合物，铸成一种形状并冷却成锭。 然后可以将锭形成医疗植入物并任选地退火。

公开(公告)号：US20150112447A1

公开(公告)日：2015-04-23

申请号：US14584130

申请日：2014-12-29

申请人： Zhiyue Xu

发明人： Zhiyue Xu

IPC分类号： A61F2/02 ,  A61B17/68

CPC分类号： A61F2/02 ,  A61B17/68 ,  A61B2017/00004 ,  A61F2210/0004 ,  A61L17/06 ,  A61L27/427 ,  A61L27/58 ,  A61L31/124 ,  A61L31/148 ,  A61L2400/12

摘要： A medical implant includes a metal composite that contains a cellular nanomatrix having a metallic nanomatrix material and a metal matrix disposed in the cellular nanomatrix, the medical implant being configured to disintegrate in response to contact with a fluid. A method for repairing tissue includes disposing an implant in a patient, the implant including a metal composite which contains: a cellular nanomatrix having a metallic nanomatrix material; and a metal matrix disposed in the cellular nanomatrix; contacting tissue of the patient with the implant, the tissue being in need of repair; and non-operatively removing the implant to repair the tissue.

摘要翻译： 医疗植入物包括金属复合物，其包含具有金属纳米线材料的细胞纳米线性矩阵和设置在细胞纳米基质中的金属基体，所述医疗植入物构造成响应于与流体的接触而分解。 修复组织的方法包括将植入物放置在患者体内，所述植入物包括金属复合物，其包含：具有金属纳米线材料的细胞纳米线; 和设置在所述细胞纳米基质中的金属基质; 使患者的组织与植入物接触，所述组织需要修复; 并且非操作地移除植入物以修复组织。