公开(公告)号：US20240335595A1

公开(公告)日：2024-10-10

申请号：US18747602

申请日：2024-06-19

申请人： RxFiber, llc

发明人： Robert D. TORGERSON

IPC分类号： A61L31/16 ,  A61L17/06 ,  A61L17/10 ,  A61L29/06 ,  A61L29/14 ,  A61L31/06

CPC分类号： A61L31/16 ,  A61L17/06 ,  A61L29/148 ,  A61L31/06 ,  A61L17/105 ,  A61L29/06

摘要： Medical grade yarns, medical devices constructed of such yarns, and methods for making such yarns and devices are described. Polyester drawn fibers, and more particularly high strength and high tenacity micro polyester fibers for use in medical devices, and methods of preparing the same are provided.

公开(公告)号：US20220202988A1

公开(公告)日：2022-06-30

申请号：US17497800

申请日：2021-10-08

申请人： Tepha, Inc.

发明人： Simon F. Williams ,  Said Rizk ,  David P. Martin

IPC分类号： A61L27/18 ,  A61F2/00 ,  A61F2/12 ,  A61L17/10 ,  A61L27/56 ,  A61L27/58 ,  A61L31/06 ,  A61L31/14 ,  A61L17/12 ,  A61L27/54 ,  D02G3/04 ,  D02G3/44 ,  A61L17/06 ,  C08L65/00 ,  C08L67/00

摘要： Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings and receptacles are made from meshes, webs, lattices, non-wovens, films, fibers, and foams, and contain antibiotics such as rifampin and minocycline.

公开(公告)号：US10106402B2

公开(公告)日：2018-10-23

申请号：US12985549

申请日：2011-01-06

申请人： Dong Keun Han ,  Kwi Deok Park ,  Jong Hee Kang ,  Bong Soo Lee ,  Ji Yeon Choi ,  Chang Hun Kum

发明人： Dong Keun Han ,  Kwi Deok Park ,  Jong Hee Kang ,  Bong Soo Lee ,  Ji Yeon Choi ,  Chang Hun Kum

IPC分类号： B32B5/16 ,  A61L31/10 ,  B82Y5/00 ,  A61L17/06 ,  A61L27/04 ,  A61L27/34 ,  A61L27/58 ,  A61L31/02 ,  A61L31/14

摘要： Disclosed are biomedical implants comprising surface-modified metal particles and biodegradable polymers; its use for suppressing inflammation; and a method for preparing a biomedical material, comprising: (a) modifying surface of basic metal particles with a polymer to obtain surface-modified metal particles; and (b) mixing the surface-modified metal particles with a biodegradable polymer, followed by manufacturing a biodegradable biomedical implant, or coating the resulting mixture on a conventional biomedical implant.

公开(公告)号：US09937156B2

公开(公告)日：2018-04-10

申请号：US15029222

申请日：2014-10-16

申请人： The Board of Regents of the University of Texas System

发明人： Eric M. Small ,  Eric N. Olson

IPC分类号： A61K31/42 ,  A61K45/06 ,  A61F13/00 ,  A61G10/02 ,  A61K9/06 ,  A61K9/08 ,  A61K9/14 ,  A61L17/00 ,  A61L17/06 ,  A61M1/00 ,  A61N1/04 ,  A61N5/06 ,  A61N7/00 ,  C07K16/18 ,  C12N15/113 ,  A61L15/44 ,  A61L26/00

CPC分类号： A61K31/42 ,  A61F13/00021 ,  A61G10/026 ,  A61K9/06 ,  A61K9/08 ,  A61K9/14 ,  A61K45/06 ,  A61L15/44 ,  A61L17/005 ,  A61L17/06 ,  A61L26/0066 ,  A61L2300/204 ,  A61L2300/412 ,  A61M1/0088 ,  A61N1/0468 ,  A61N5/062 ,  A61N7/00 ,  C07K16/18 ,  C12N15/113

摘要： The present disclosure concerns uses for isoxazole compounds or salts or analogs thereof for the treatment of wounds. The present disclosure also concerns devices for delivering a isoxazole compound or salts or an analogs thereof to a wound site.

公开(公告)号：US09888992B2

公开(公告)日：2018-02-13

申请号：US14755826

申请日：2015-06-30

申请人： NOVUS SCIENTIFIC AB

发明人： Per Egnelöv

IPC分类号： A61L17/00 ,  A61B17/04 ,  A61F2/00 ,  A61L17/06 ,  A61B17/06 ,  D02G3/44 ,  A61B17/00

CPC分类号： A61F2/0063 ,  A61B17/06166 ,  A61B2017/00004 ,  A61B2017/0618 ,  A61L17/06 ,  D02G3/448 ,  Y10T428/2929 ,  Y10T428/2931

摘要： The invention relates to a resorbable multifilament comprising a number of individual resorbable filaments of a first type having a first degradation time and a number of individual resorbable filaments of a second type having a second degradation time, wherein the filaments of the first type and the filaments of the second type are arranged in close relationship to form a composite multifilament having a length and a specific composite cross-section comprising cross-sections of the individual filaments of the first type and second type, wherein the cross-sections of the individual filaments of the first and second type are located at determined relative positions, wherein the relative positions amongst the individual cross-sections of the filaments of the first and second types are invariant over the length of the composite multifilament.

公开(公告)号：US20180008744A1

公开(公告)日：2018-01-11

申请号：US15269802

申请日：2016-09-19

申请人： BIOACTIVE SURGICAL, INC.

发明人： Richard H. Spedden ,  Laura J. Pingel ,  Lew C. Schon

IPC分类号： A61L17/00 ,  A61L17/06 ,  A61B17/06 ,  D06B1/10 ,  A61B17/00

CPC分类号： A61L17/005 ,  A61B17/06114 ,  A61B17/06166 ,  A61B2017/00884 ,  A61B2017/00893 ,  A61B2017/06185 ,  A61L17/06 ,  A61L2300/404 ,  A61L2300/414 ,  A61L2300/42 ,  A61L2300/45 ,  A61L2300/604 ,  A61L2300/64 ,  D06B1/10

摘要： Materials and methods for immobilizing bioactive molecules, stem and other precursor cells, and other agents of therapeutic value in surgical sutures and other tissue scaffold devices are described herein. Broadly drawn to the integration and incorporation of bioactive materials into suture constructs, tissue scaffolds and medical devices, the present invention has particular utility in the development of novel systems that enable medical personnel performing surgical and other medical procedures to utilize and subsequently reintroduce bioactive materials extracted from a patient (or their allogenic equivalents) to a wound or target surgical site.

公开(公告)号：US09861570B2

公开(公告)日：2018-01-09

申请号：US14947409

申请日：2015-11-20

申请人： Allergan Holdings France S.A.S.

发明人： Geoffrey C. Gurtner ,  Kenneth N. Horne ,  Jayakumar Rajadas

IPC分类号： A61L31/04 ,  A61L27/20 ,  A61Q19/08 ,  C08L5/08 ,  A61K8/73 ,  A61L15/28 ,  A61L17/06 ,  C08B37/08 ,  A61K8/02 ,  A61K8/42 ,  A61L17/00 ,  A61L17/04 ,  A61L27/54 ,  A61K8/65 ,  A61L17/10

CPC分类号： A61K8/735 ,  A61K8/0216 ,  A61K8/027 ,  A61K8/42 ,  A61K8/65 ,  A61K2800/805 ,  A61L15/28 ,  A61L17/005 ,  A61L17/04 ,  A61L17/06 ,  A61L17/10 ,  A61L27/20 ,  A61L27/54 ,  A61L31/042 ,  A61L2300/402 ,  A61L2430/34 ,  A61Q19/08 ,  C08B37/0072 ,  C08L5/08 ,  C08L2205/025 ,  Y10T428/2929

摘要： The present invention provides threads of hyaluronic acid, and/or derivatives thereof, methods of making thereof and uses thereof, for example, in aesthetic applications (e.g., dermal fillers), surgery (sutures), drug delivery, etc.

公开(公告)号：US09642930B2

公开(公告)日：2017-05-09

申请号：US14602601

申请日：2015-01-22

申请人： DePuy Mitek, LLC

发明人： Ilya Koyfman ,  Terry E. Lawler ,  Robert C. Di Luccio ,  Dennis D. Jamiolkowski

IPC分类号： A61B17/04 ,  A61L17/10 ,  A61B17/06 ,  A61L17/00 ,  A61L17/04 ,  A61L17/06 ,  A61L17/14 ,  D04C1/12 ,  A61B17/00

CPC分类号： A61L17/10 ,  A61B17/0401 ,  A61B17/06066 ,  A61B17/06166 ,  A61B2017/00004 ,  A61B2017/00893 ,  A61B2017/0414 ,  A61B2017/0458 ,  A61B2017/06171 ,  A61L17/005 ,  A61L17/04 ,  A61L17/06 ,  A61L17/105 ,  A61L17/145 ,  A61L2300/402 ,  A61L2300/406 ,  A61L2300/41 ,  D04C1/12 ,  D10B2509/04

摘要： A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.

公开(公告)号：US09228027B2

公开(公告)日：2016-01-05

申请号：US13060919

申请日：2009-09-02

申请人： Geoffrey C. Gurtner ,  Kenneth N. Horne ,  Jayakumar Rajadas

发明人： Geoffrey C. Gurtner ,  Kenneth N. Horne ,  Jayakumar Rajadas

IPC分类号： A61K31/728 ,  A61K9/70 ,  C08B37/08 ,  A61L15/28 ,  A61L17/06 ,  A61L27/20 ,  A61L31/04 ,  C08L5/08

CPC分类号： A61K8/735 ,  A61K8/0216 ,  A61K8/027 ,  A61K8/42 ,  A61K8/65 ,  A61K2800/805 ,  A61L15/28 ,  A61L17/005 ,  A61L17/04 ,  A61L17/06 ,  A61L17/10 ,  A61L27/20 ,  A61L27/54 ,  A61L31/042 ,  A61L2300/402 ,  A61L2430/34 ,  A61Q19/08 ,  C08B37/0072 ,  C08L5/08 ,  C08L2205/025 ,  Y10T428/2929

摘要： The present invention provides threads of hyaluronic acid, and/or derivatives thereof, methods of making thereof and uses thereof, for example, in aesthetic applications (e.g., dermal fillers), surgery (sutures), drug delivery, etc.

摘要翻译： 本发明提供透明质酸和/或其衍生物的丝线，其制备方法及其用途，例如在美学应用（例如真皮填充剂），手术（缝线），药物递送等中。

公开(公告)号：US09080263B2

公开(公告)日：2015-07-14

申请号：US13370433

申请日：2012-02-10

申请人： Per Egnelöv

发明人： Per Egnelöv

IPC分类号： A61L17/00 ,  A61B17/04 ,  D02G3/44 ,  A61L17/06 ,  A61F2/00 ,  A61B17/06 ,  A61B17/00

CPC分类号： A61F2/0063 ,  A61B17/06166 ,  A61B2017/00004 ,  A61B2017/0618 ,  A61L17/06 ,  D02G3/448 ,  Y10T428/2929 ,  Y10T428/2931

摘要： The invention relates to a resorbable multifilament comprising a number of individual resorbable filaments of a first type having a first degradation time and a number of individual resorbable filaments of a second type having a second degradation time, wherein the filaments of the first type and the filaments of the second type are arranged in close relationship to form a composite multifilament having a length and a specific composite cross-section comprising cross-sections of the individual filaments of the first type and second type, wherein the cross-sections of the individual filaments of the first and second type are located at determined relative positions, wherein the relative positions amongst the individual cross-sections of the filaments of the first and second types are invariant over the length of the composite multifilament.

摘要翻译： 本发明涉及一种可吸收复丝，其包含多个具有第一种降解时间的第一类型的单独可再吸收长丝和具有第二种降解时间的第二种类型的单独可再吸收长丝，其中第一类型的长丝和长丝 第二类型的横截面被布置成紧密关系以形成具有长度和特定复合截面的复合复丝，该复合复丝包括第一类型和第二类型的单丝的横截面，其中单根长丝的横截面 第一和第二类型位于确定的相对位置，其中第一和第二类型的长丝的各个横截面之间的相对位置在复合复丝的长度上是不变的。